Intensified early detection
As one of the 15 centers of the Breast and Ovarian Cancer Consortium, we at the Institute of Diagnostic and Interventional Radiology at the MHH are responsible for intensive early detection for women with an increased risk of breast cancer. Before the screening begins, the patient must present herself at the Institute of Human Genetics to have her individual risk determined. The human genetic findings are discussed in detail with the patient and an expert opinion is drawn up, which also specifies the screening intervals.
A distinction is made between three risk groups:
Group 1 - statistically increased (calculated) risk without evidence of a mutation
| Clinical examination | from the age of 30 - annually |
| Sonography | from the age of 30 - annually |
| MRI | from the age of 30 - annually |
| Mammography | from the age of 40 - every 1-2 years |
Int. early detection up to the age of 50. After that, regular care/screening (the risk of breast cancer is only slightly higher than the risk in the average population).
Group 2 - Detection of a mutation in so-called "moderate risk genes" such as CHEK 2 and RAD51 C gene
| Clinical examination | from the age of 30 - annually |
| Sonography | from the age of 30 - annually |
| MRI | from the age of 30 - annually |
| Mammography | from the age of 40 - every 1-2 years |
Int. early detection up to the age of 70.
Group 3 - Detection of a mutation in the BRCA 1 or 2 gene
| Clinical examination | from the age of 25 - every six months |
| Sonography | from the age of 25 - every six months |
| MRI | from the age of 25 - annually |
| Mammography | from the age of 40 - every 1-2 years |
Int. early detection up to the age of 70.
For family members who are diagnosed very early, early detection begins 5 years before the earliest age of onset.