- 2020-

Ackermann M *, Frohn J *, Reichardt M*, Osterhoff M, Sprung M, Westermeier F, Tzankov A, Kühnel M, Jonigk D *, Salditt T *. 3d Virtual Pathohistology of Lung Tissue from Covid-19 Patients based on Phase Contrast X-ray Tomography. eLife 2020 (Impact Factor 2019: 6.830)

*contributed equally

 

Derlin T, Jaeger B, Jonigk D, Apel R, Freise J, Shin HO, Weiberg D, Warnecke G, Ross T, Wester HJ, Seeliger B, Welte T, Bengel F, Prasse A. Clinical Molecular Imaging of Pulmonary CXCR4 Expression to Predict Outcome of Pirfenidone Treatment in IPF. CHEST 2020 (Impact Factor 2019: 9.657)

 

Willers M, Ulas T, Völlger L, Vogl T, Heinemann AS, Pirr S, Pagel J, Fehlhaber B, Halle O, Schöning J, Schreek S, Löber U, Essex M, Hombach P, Graspeuntner S, Basic M, Bleich A, Cloppenborg-Schmidt K, Künzel S, Jonigk D, Rupp J, Hansen G, Förster R, Baines JF, Härtel C, Schultze JL, Forslund SK, Roth J, Viemann D. S100A8 and S100A9 are Important for Postnatal Development of Gut Microbiota and Immune System in Mice and Infants. Gastroenterology. 2020 Aug 14:S0016-5085(20)35058-7. doi: 10.1053/j.gastro.2020.08.019. Online ahead of print. PMID: 32805279 (Impact Factor 2019: 15.130)

 

Calabrese F, Schiavon M, Perissinotto E, Lunardi F, Marulli G, Di Gregorio G, Pezzuto F, Vuljan SE, Forin E, Wiegmann B, Jonigk D, Warnecke G, Rea F. Organ care system lung resulted in lower apoptosis and inos expression in donor lungs.  Am J Transplant. 2020 Jul 11. doi: 10.1111/ajt.16187. Online ahead of print. PMID: 32652873 (Impact Factor 2018: 7.163)

 

Höfer A, Jonigk D, Hartleben B, Verboom M, Hallensleben M, Manns MP, Taubert R. Non-invasive screening for subclinical liver graft injury in adults via donor-specific anti-HLA antibodies. Scientific Reports 2020 (Impact Factor 2019: 4.12)

 

Kommoss F, Schwab C, Tavernar L, Schreck J, Wagner W, Merle U, Jonigk D, Schirmacher P, Longerich T. Pathologie der schweren COVID-19-bedingten Lungenschädigung - Hinweise auf Mechanismen und therapeutische Ansätze. Deutsches Ärzteblatt (Impact Factor 2019: 4,469)

 

Tumpara S, Martinez-Delgado B, Gomez-Mariano G, Liu B, DeLuca DS, Korenbaum E, Jonigk D, Jugert F, Wurm FM, Maria J, Welte T, Janciauskiene S. The delivery of α1-antitrypsin therapy through transepidermal route: worthwhile to explore. Front Pharmacol 2020 Jul 3;11:983. doi: 10.3389/fphar.2020.00983. eCollection 2020 PMID: 32719598 (Impact Factor: 3.831)

 

Ackermann M, Verleden SE, Kuehnel M, Haverich A, Welte T, Laenger F, Vanstapel A, Werlein C, Stark H, Tzankov A, Li WW, Li VW, Mentzer SJ, Jonigk D. Pulmonary Vascular Endothelialitis, Thrombosis and Angiogenesis in COVID-19. N Engl J Med. 2020 May 21. doi: 10.1056/NEJMoa2015432. PMID: 32437596. (Impact Factor 2019: 70.670)

 

Sieweke JT, Akin M, Stetskamp S, Riehle CM, Jonigk D, Flierl U, Pfeffer TJ, Hirsch VGW, Hoeper M, Kühn C. Mechanical Circulatory Support in Refractory Cardiogenic Shock due to Influenza Virus-Related Myocarditis. Eur Respir J. 2020 May 12. pii: 2000925. doi: 10.1183/13993003.00925-2020 (Impact Factor 2018: 12.242)

 

Schirmer B, Rother T, Brüsch I, Bleich A, Werlein C, Jonigk D, Seifert R, Neumann D*. Genetic deficiency of the histamine H4-receptor reduces experimental colorectal cancer in mice. Cancers (Basel) 2020 Apr 8;12(4). pii: E912. doi: 10.3390/cancers12040912 (Impact Factor 2018: 6.162)

 

Kamp JC, Jonigk D, Hinrichs JB, Hoeper M, Schönhofer B, Ernst D, Welte T, Suhling. Recurrent life-threatening pneumonitis in a 37-year-old woman. CHEST 2020 (Impact Factor 2018: 9.657)

 

Neubert L*, Borchert P*, Stark H, Hoefer A, Vogel-Claussen J, Warnecke G, Eubel H, Kuenzler P, Kreipe HH, Hoeper MM, Kuehnel M#, Jonigk D#. Molecular Profiling of Vascular Remodeling in Chronic Pulmonary Disease. Am J Pathol. 2020 Apr 7. pii: S0002-9440(20)30145-0. doi: 10.1016/j.ajpath.2020.03.008 (Impact Factor 2017: 4.189)

 

Ackermann M, Haake K, Kempf H, Kaschutnig P, Weiss A-C, Nguyen A HH, Abeln M, Merkert S, Kühnel MP, Hartmann D, Jonigk D, Thum T, Kispert A, Milsom MD, Lachmann N. A 3D iPSC-differentiation model identifies interleukin-3 as a regulator of early human hematopoietic specification. Haematologica 2020 Apr 23. pii: haematol.2019.228064. doi: 10.3324/haematol.2019.228064 (Impact Factor 2018: 7.570)

 

Haake K, Neehus AL, Buchegger T, Kühnel MP, Blank P, Philipp F, Oleaga-Quintas C, Schulz A, Grimley M, Goethe R, Jonigk D, Kalinke U, Boisson-Dupuis S, Casanova JL, Bustamante J, Lachmann N. Patient iPSC-derived macrophages to study inborn errors of the IFN-γ responsive pathway. Cells 2020 Feb 19;9(2):483. doi: 10.3390/cells9020483 (Impact Factor 2017: 4.826)

 

Verleden SE*, Vanstapel A*, De Sadeleer L, Weynand B, Boone M, Verbeken E, Piloni D, Van Raemdonck D, Ackermann M, Jonigk D, Verschakelen J, Wuyts WA. Quantitative analysis of airway obstruction in lymphangio-leio-myomatosis. Eur Respir J, 2020 Feb 27:1901965. doi: 10.1183/13993003.01965-2019 (Impact Factor 2018: 12.242)

 

Jiménez Delgado S ∗, Dehmel S ∗, Twisterling E, Wichmann J, Jonigk D, Warnecke G, Braubach P, Fieguth HG, Wilkens L, Dahlmann F, Kaup FJ, Eggel A ∗, Knauf S ∗,  Sewald K ∗, Braun A ∗. Disruptive anti-IgE inhibitors prevent mast cell–dependent early airway response in viable atopic lung tissue. JACI 2019  pii: S0091-6749(19)31485-X. doi: 10.1016/j.jaci.2019.11.002 (Impact Factor 2018: 14.110)

 

Bogaard HJ, Legchenko E, Ackermann M, Kühnel MP, Jonigk D, Chaudhary KR, Sun X, Stewart DJ, Hansmann G. The Adult Sprague-Dawley Sugen-Hypoxia Rat Is Still "the One:" A Model of Group 1 Pulmonary Hypertension: Reply to Le Cras and Abman. Am J Respir Crit Care Med. 2019 Nov 26. doi: 10.1164/rccm.201910-1983LE. (Impact Factor: 16.494)

 

Melchert J, Henningfeld KA, Richts S, Lingner T, Jonigk D, Pieler T. The secreted BMP antagonist ERFE is required for the development of a functional circulatory system in Xenopus. Dev Biol. 2019 Dec 14. pii: S0012-1606(19)30366-5. doi: 10.1016/j.ydbio.2019.12.007. (Impact Factor 2018: 3.262)

 

Ackermann M, Stark H, Neubert L, Schubert S, Borchert P, Linz F, Wagner W, Stiller W, Wielpütz M, Hoefer A, Haverich A, Mentzer S, Shah H, Welte T, Kuehnel M, Jonigk D. Morphomolecular motifs of pulmonary neoangiogenesis in interstitial lung diseases. Eur Respir J. 2020 Mar 12;55(3):1900933. doi: 10.1183/13993003.00933-2019 PMID: 31806721.  (Impact Factor 2018: 12.242)

 

Poehnert D, Neubert L, Klempnauer J, Borchert P, Jonigk D, Winny M. Comparison of adhesion prevention capabilities of the modified starch powder-based medical devices 4DryField® PH and Arista™ AH in the Optimized Peritoneal Adhesion Model. Int J Med Sci. 2019 Sep 19;16(10):1350-1355. doi: 10.7150/ijms.33277. (Impact Factor 2018: 2.399)

 

Höfer A, Jonigk D, Hartleben B, Verboom M, Hallensleben M, Hübscher SG, Manns MP, *Jaeckel E, *Taubert R. : DSA are associated with more graft injury, more fibrosis and upregulation of rejection associated transcripts in subclinical rejection. Transplantation 2019 doi: 10.1097/TP.0000000000003034. (Impact Factor 2018/19: 4.593)

Ercetin E, Richtmann S, Martinez-Delgado B, Gomez-Mariano G, Wrenger S, Korenbaum E, Liu B, DeLuca D, Kühnel MP, Jonigk D, Yuskaeva K, Warth A, Muley T, Winter H, Meister M, Welte T, Janciauskiene S, Schneider M. Clinical significance of SERPINA1 gene and its encoded alpha1-antitrypsin protein in NSCLC. Cancers 2019; 11(9). pii: E1306. doi: 10.3390/cancers11091306 (Impact Factor 2018: 6.162)

Jonigk D, Stark H, Braubach P, Neubert Lavinia, Shin HO, Izykowski N, Welte Tobias, Janciauskiene S, Warnecke G, Haverich A, Kuehnel M, Laenger F. Morphological and molecular motifs of fibrosing pulmonary injury patterns. J Pathol Clin Res. 2019 doi: 10.1002/cjp2.141. (Impact Factor 2015: 7.381)

Madrahimov N, Natanov R, Khalikov A, Boyle EC, Jonigk D, Knoefel AK, Siemeni T, Haverich A. Warming and cooling device using thermoelectric Peltier elements tested on male mice. Laboratory Animals 2019 doi: 10.1177/0023677219873687 (Impact Factor 2018: 1.117)

 

Kordes A, Preusse M, Willger S, Braubach P, Jonigk D, Haverich A, Warnecke G, Häussler S. Genetically diverse Pseudomonas aeruginosa populations display similar transciptomic profiles in a cystic fibrosis explanted lung. Nat Commun. 2019 10(1): 3397. doi: 10.1038/a41467-019-11414-3. (Impact Factor 2018: 11.88)

Schmidt H, Braubach P, Schilpp C, Lochbaum R, Neuland K, Thompson K, Jonigk D, Frick M, Dietl P, Wittekindt O. IL-13 impairs tight junctions in airway epithelia. Int J Mol Sci. 2019; 20(13). pii: E3222. doi: 10.3390/ijms20133222 (Impact Factor 2018: 4.183)

Bickes MS, Pirr S, Heinemann AS, Fehlhaber B, Halle S, Völlgrt L,Willers M, Richter M, Böhne C, Albrecht M, Langer M, Pfeifer S, Jonigk D, Vieten G, Ure B, von Kaisenberg  C, Förster R, von Köckritz-Blickwede M, Hansen G, Viemann D. Constitutive TNF-α signaling in neonates is essential for the development of tissue-resident leukocyte profiles at barrier sites. FASEB J. 2019: fj201900796R. doi: 10.1096/fj.201900796R. (Impact Factor 2016: 5.498)

Funken D, Schmidtmayer U, Durisin M, Jonigk D, Baumann U, Dittrich AM. Listen carefully - an unusual cause of neonatal stridor. American Journal of Respiratory and Critical Care Medicine 2019 (AJRCCM). doi: 10.1164/rccm.201811-2213IM. (Impact Factor 2018: 15.24)

Tort Tarres M, Aschenbrenner F, Maus R, Stolper J, Schuette L, Knudsen L, Lopez-Rodriguez E, Jonigk D, Kuehnel M, DeLuca D, Prasse A, Welte T, Gauldie J, Kolbm M, Maus U. The Fms-like tyrosine kinase-3 ligand/lung dendritic cell axis contributes to regulation of pulmonary fibrosis. Thorax 2019. pii: thoraxjnl-2018-212603. doi: 10.1136/thoraxjnl-2018-212603. (Impact Factor 2017: 9.655)

Eggers H, Krüger M, Stange K, Jonigk D, Biancosiono C, Rodt T, Fühner T, Murray T, Grünwald V, Ivanyi P. Sarcoid-like lesions mimicking pulmonary metastasis. Oncol Res Treat. 2019 28: 1-5. doi: 10.1159/000500206 (Impact Factor 2018: 1.292)

Weiss A, Neubauer MC, Yerabolu D, Kojonazarov B, Schlueter BC, Neubert L, Jonigk D, Baal N, Ruppert C, Dorfmuller P, Pullamsetti S, Weissmann N, Ghofrani HA, Grimminger F, Seeger W, Schermuly RT. Targeting cyclin-dependent kinases for the treatment of pulmonary arterial hypertension. Nat Commun 2019; 10(1): 2204. doi: 10.1038/s41467-019-10135-x. (Impact Factor 2017: 12.353)

 

Sarikouch S, Theodoridis K, Hilfiker A, Boethig D, Laufer G, Andreas M, Cebotari S, Tudorache I, Bobylev D, Neubert L, Teiken K, Robertus JL, Jonigk D, Beerbaum P, Haverich A, Horke A. Early insight into In-vivo recelluarization of cell-free allogenic heart valves. Ann Thorac Surg. pii: S0003-4975(19)30414-X. doi: 10.1016/j.athoracsur.2019.02.058. (Impact Factor 3.770)

 

Barman S, Li X, Haigh S, Kondrikov D, Mahboubi K, Bordan Z, Stepp DW, Zhou J, Wang Y, Weintraub DS, Traber P, Snider W, Jonigk D, Sullivan J, Crislip GR, Butcher JT, Thompson J, Su Y, Chen F, Fulton DJR. Galectin-3 is expressed in Vascular Smooth Muscle Cells and Promotes Pulmonary Hypertension through changes in Proliferation, Apoptosis and Fibrosis. Am J Physiol Lung Cell Mol Physiol. 2019; 316(5): L784-L797. doi: 10.1152/ajplung.00186.2018. (Impact Factor 2015: 4.47)

 

Neubert L*, Borchert P*, Shin H, Linz F, Wagner WL, Warnecke G, Laenger F, Haverich A, Stark H, Hoeper MM, Kuehnel M, Ackermann M°, Jonigk D°. Comprehensive Three-dimensional Morphology of Neoangiogenesis in Pulmonary Veno-occlusive Disease and Pulmonary Capillary Hemangiomatosis. J Pathol Clin Res 2019; 5(2): 108-114. doi: 10.1002/cjp2.125. (Impact Factor 2015: 7.381)

                *shared first author, °shared last author

 

Zimpfer A, Schneider B, Blanck O, Riedel K, Zhivov A, Jonigk D, Erbersdobler A, Jünemann A, Andratschke N, Hildebrandt G, Guthoff RF, Kakkassery V. Pathologic Features of Tumor Activity and Stability in Uveal Melanoma Specimens after Fractionated CyberKnife Radiosurgery. Pathol Oncol Res 2019; 25(2): 731-740. doi: 10.1007/s12253-018-00565-1. (Impact Factor 2017: 1.935)

 

Lippmann T, Braubach P, Ettinger M, Kuehnel MP, Länger F, Jonigk D. Fluorescence in situ hybridisation (FISH) for diagnosis of periprosthetic joint infection in formalin-fixed paraffin-embedded surgical tissues. J Bone Joint Surg Am. 2019; 101(2): e5. doi: 10.2106/JBJS.18.00243. (Impact Factor 2017: 4.583)

 

Serban KA, Mikosz A, Strange C, Janciauskiene SM, Stolk J, Jonigk D, Sandhaus RA, Petrache I. Lectin Complement Pathway in Emphysema. Am J Respir Crit Care Med. 2019; 199(5): 659-661. doi: 10.1164/rccm.201807-1380LE. (Impact Factor 2017: 15.239)

 

Renne J, Gutberlet M, Voskrebenzev A, Kern A, Kaireit T, Hinrichs J, Zardo P, Warnecke G, Krüger M, Braubach P, Jonigk D, Haverich A, Wacker F, Vogel-Claussen J, Zinne N. Multiparametric MRI for organ quality assessment in a porcine Ex-Vivo lung perfusion system. PLoS ONE 2018; 13(12): e0209103. doi: 10.1371/journal.pone.0209103. (Impact Factor 2017: 2.766)

 

Ackermann M, Kempf H, Hetzel M, Hesse C, Rafiei Hashtchin A, Brinkert K, Schott J, Haake K, Kühnel MP, Glage S, Ferreira de Figueiredo CS, Jonigk D, Sewald K, Schambach A, Wronski S, Moritz T, Martin U, Zweigerdt R, Munder A. Bioreactor-based mass production of human iPSC-derived macrophages enables immunotherapies against bacterial airway infections. Nat Commun 2018; 9(1): 5088. doi: 10.1038/s41467-018-07570-7. (Impact Factor 2017: 12.353)

 

Danov O, Jiménez Delgado SM, Obernolte H, Seehase S, Dehmel S, Braubach P, Fieguth HG, Matschiner G, Fitzgerald M, Jonigk D, Knauf S, Pfennig O, Warnecke G, Wichmann J, Braun A, Sewald K. Human lung tissue provides highly relevant data about efficacy of new anti-asthmatic drugs. PLoS ONE 2018; 13(11): e0207767. doi: 10.1371/journal.pone.0207767. (Impact Factor 2017: 2.766)

 

Figueiredo C, Carvalho Oliveira M, Chen-Wacker C, Jansson K, Höffler K, Yuzefovych Y, Pogozhykh O, Jin Z, Kühnel MP, Jonigk D, Wiegmann B, Sommer W, Haverich A, Warnecke G, Blasczyk R. Immunoengineering of the vascular endothelium to silence MHC expression during normothermic ex vivo lung perfusion. Hum Gene Ther 2018. doi: 10.1089/hum.2018.117. (Impact Factor 2017: 4.241)

 

Sommer W, Salman J, Avsar M, Hoeffler HK, Jansson K, Siemeni Monthe NT, Knoefel AK, Ahrens L, Poyanmehr R, Tudorache I, Braubach P, Jonigk D, Haverich A, Warnecke G. Prediction of transplant outcome after 24-hour ex vivo lung perfusion using the Organ Care System in a porcine lung transplantation model. Am J Transplant. 2019; 19(2): 345-355. doi: 10.1111/ajt.15075 (Impact Factor 2017: 6.493)

 

Eickhoff L, Golpon H, Zardo P, Suhling H, Welte T, Jonigk D, Gottlieb J, Fuehner T. Endobronchial Ultrasound in Suspected Non-Malignant Mediastinal Lymphadenopathy. Pneumologie 2018; 72(8): 559-567. doi: 10.1055/a-0583-0265. (Impact Factor 2015: 0.48)

 

Salman J, Jansson K, Siemeni T, Sommer W, Knoefel AK, Ahrens L, Nakagiri T, Ius F, Tudorache I, Kruse B, Thissen S, Jonigk D, Strüber M, Haverich A, Warnecke G, Avsar M. Role for primary immunosuppression with everolimus after pulmonary transplantation. Transpl Immunol 2018; 49: 12-19. doi: 10.1016/j.trim.2018.03.005. (Impact Factor 2016: 1.780)

 

Legchenko E, Chouvarine P, Borchert P, Fernandez-Gonzalez A, Snay E, Meier M, Maegel L, Mitsialis S.A, Rog-Zielinska E, Kourembanas S, Jonigk D, Hansmann G. The PPARγ Agonist Pioglitazone Reverses Pulmonary Hypertension and Prevents Right Heart Failure through Fatty Acid Oxidation. Sci Transl Med 2018; 10(438). doi: 10.1126/scitranslmed.aao0303. (Impact Factor 2016: 16.761)

 

Teiken K, Kuehnel MP, Rehkaemper J, Kreipe H, Laenger F, Hussein K, Jonigk D. Non-canonical WNT6/WNT10a Signal Factor Expression in EBV+ Post-transplant Smooth Muscle Tumors. Clin Sarcoma Res 2018; 8: 10. doi: 10.1186/s13569-018-0096-8. (Impact Factor 2015: 2.22)

 

Diestelhorst J, Junge N, Jonigk D, Schlue J, Falk C, Manns MP, Baumann U, Jaeckel E, Taubert R. Baseline IL-2 and the AIH score can predict the response to standard therapy in paediatric autoimmune hepatitis. Sci Rep 2018; 8(1): 419. doi: 10.1038/s41598-017-18818-5. (Impact Factor 2016: 4.259)

 

Neehus AL, Lam J, Haake K, Merkert S, Schmidt N, Mucci A, Ackermann M, Schubert M, Happle C, Kühnel MP, Blank P, Philipp F, Goethe R, Jonigk D, Martin U, Kalinke U, Baumann U, Schambach A, Roesler J, Lachmann N. Impaired IFNγ-Signaling and Mycobacterial Clearance in IFNγR1-Deficient Human iPSC-Derived Macrophages. Stem Cell Reports 2018; 10(1): 7-16. doi: 10.1016/j.stemcr.2017.11.011. (Impact Factor 2016: 7.338)

 

Hetzel M, Mucci A, Blank P, Hai Ha Nguyen A, Schiller J, Halle O, Kühnel MP, Billig S, Meineke R, Brand D, Herder V, Baumgärtner W, Bange FC, Goethe R, Jonigk D, Förster R, Gentner B, Casanova JL, Bustamante J, Schambach A, Kalinke U, Lachmann N. Hematopoietic stem cell gene therapy for IFNγR1 deficiency protects mice from mycobacterial infections. Blood 2018; 131(5): 533-545. doi: 10.1182/blood-2017-10-812859. (Impact Factor 2016: 13.164)

 

Neuhaus V, Danov O, Konzok S, Obernolte H, Dehmel S, Braubach P, Jonigk D, Fieguth H-G, Zardo P, Warnecke G, Martin C, Braun A, Sewald K. Assessment of the Cytotoxic and Immunomodulatory Effects of Substances in Human Precisioncut Lunge Slices. J Vis Exp 2018; 9(135). doi: 10.3791/57042. (Impact Factor 2016: 1.232)

 

Ackermann M, Gaumann A, Mentzer SJ, Hinrichs JB, Warnecke G, Hoeper MM, Braubach P, Kuehnel M, Mägel L, Jonigk D. Plexiform vasculopathy in chronic thromboembolic pulmonary hypertension. Am J Respir Crit Care Med 2017; 196(8). doi: 10.1164/rccm.201703-0591IM. (Impact Factor 2016: 13.204)

 

Aichler M, Kunzke T, Buck A, Sun N, Ackermann M, Jonigk D, Gaumann A, Walch A. Molecular similarities and differences from human pulmonary fibrosis and corresponding mouse model - MALDI imaging mass spectrometry in comparative medicine. Lab Invest 2017; 98(1): 141-149. doi: 10.1038/labinvest.2017.110. (Impact Factor 2016: 4.857)

 

Hess R, Wujak L, Hesse C, Sewald K, Jonigk D, Warnecke G, Fieguth H, Demaat S, Maas C, Bonella F, Preissner KT, Weiss B, Schaefer L, Kuebler W, Markart P, Wygrecka M. Coagulation factor XII regulates inflammatory responses in human lungs. Thromb Haemost 2017; 117(10): 1896-1907. doi: 10.1160/TH16-12-0904. (Impact Factor 2016: 5.627)

 

Braubach P, Lippmann T, Raoult D, Lagier J, Anagnostopoulos I, Zender S, Länger FP, Kreipe H, Kühnel MP, Jonigk D. Fluorescence in situ hybridisation for diagnosis of Whipple’s disease in formalin-fixed paraffin-embedded tissue. Front Med (Lausanne) 2017; 4: 87. doi: 10.3389/fmed.2017.00087. (Impact Factor 2016: 4.076)

 

Taubert R, Wolenski M, Noyan F, Jonigk D, Schlue J, Krech T, Lichtinghagen R, Falk C, Schlaphoff V, Bantel H, Muratori L, Manns M, Jaeckel E. Hyperferritinemia and hypergammaglobulinemia predict the treatment response to standard therapy in autoimmune hepatitis. PLoS ONE 2017; 12(6): e0179074. doi: 10.1371/journal.pone.0179074. (Impact Factor 2016: 3.54)

 

Wujak L, Hesse C, Sewald K, Jonigk D, Braubach P, Warnecke G, Fieguth HG, Braun A, Lochnit G, Markart P,Schaefer L, Wygrecka M. FXII promotes proteolytic processing of the LRP1 ectodomain. BBA - General Subjects 2017; 1861(8): 2088-2098. doi: 10.1016/j.bbagen.2017.05.023. (Impact Factor 2016: 5.083)

 

Neuhaus V, Schaudien D, Golovina T, Temann UA, Thompson C, Lippmann T, Bersch C, Pfennig O, Jonigk D, Braubach P, Fieguth HG, Warnecke G, Yusibov V, Sewald K, Braun A. Assessment of long-term cultivated human precision-cut lung slices as an ex vivo system for
evaluation of chronic cytotoxicity and functionality. J Occup Med Toxicol 2017; 12: 13. doi: 10.1186/s12995-017-0158-5. (Impact Factor 2015/2016: 1.486)

 

Jeinsen N*, Mägel L, Jonigk D, Klingenberg M, Haverich A, Wilhelmi M, Böer U. Biocompatibility of intensified decellularized equine carotid arteries in a rat subcutaneous implantation model and in a human in vitro-model. Tissue Eng Part A 2017; 24(3-4): 310-321. doi: 10.1089/ten.TEA.2016.0542. (Impact Factor 2015/2016: 3.58)

 

Calvier L, Chouvarine P, Legchenko E, Hoffmann N, Geldner J, Borchert P, Jonigk D, Mozes MM, Hansmann G. PPARγ Links BMP2 and TGFβ1 Pathways in Vascular Smooth Muscle Cells, Regulating Cell Proliferation and Glucose Metabolism. Cell Metab 2017; 25(5): 1118-1134.e7. doi: 10.1016/j.cmet.2017.03.011. (Impact Factor 2016: 17.303)

 

Karadagi A, Johansson H, Zemack H, Salipalli S, Mörk L, Kannisto K, Jorns C, Stokkeland K, Gramignoli R, Strom S, Ericzon B, Jonigk D, Janciauskiene S, Nowak G, Ellis E. Exogenous alpha 1-antitrypsin down-regulates SERPINA1 expression. PLoS ONE 2017; 12(5): e0177279. doi: 10.1371/journal.pone.0177279. (Impact Factor 2016: 3.54)

 

Jansson K, Dreckmann K, Sommer W, Avsar M, Salman J1, Siemeni T, Knöfel AK, Pauksch L, Gottlieb J, Frühauf J, Werner M, Jonigk D, Strüber M, Haverich A, Warnecke G. Splenocyte infusion and whole body irradiation for induction of peripheral tolerance in porcine lung transplantation: modifications of the preconditioning regime for improved clinical feasibility. Transplantation Direct 2017; 3(7): e170. doi: 10.1097/TXD.0000000000000689. (Impact Factor 2016: n.a.)

 

Dommaschk A, Ding N, Tort Tarres M, Bittersohl LF, Maus R, Stolper J, Jonigk D, Braubach P, Lippmann T, Welte T, Maus UA. Nasopharyngeal colonization with Streptococcus pneumoniae triggers dendritic cell-dependent antibody responses against invasive disease in mice. Eur J Immunol 2017; 47(3): 540-551. doi: 10.1002/eji.201646700. (Impact Factor 2016: 4.179)

 

Sommer W, Buechler G, Jansson K, Avsar M, Knöfel A, Salman J, Hoeffler K, Siemeni T, Gottlieb J, Karstens JH, Jonigk D, Reising A, Haverich A, Strüber M, Warnecke G. Irradiation before and donor splenocyte infusion immediately after transplantation induce tolerance to lung, but not heart allografts in miniature swine. Transpl Int 2017; 30(4): 420-431. doi: 10.1111/tri.12916. (Impact Factor 2016: 3.079)

 

Zhang R, Maegel L, Jonigk D, Laenger F, Lippmann T, Zardo P, Poelzing F. Biosynthetic Nanostructured Cellulose Patch for Chest Wall Reconstruction: Five-Month Follow-up in a Porcine Model. J Invest Surg 2017; 30(5): 297-302. doi: 10.1080/08941939.2016.1244310. (Impact Factor 2016: 0.76)

 

Behler-Janbeck F, Takano T, Maus R, Stolper J, Jonigk D, Tarrés MT, Fuehner T, Prasse A, Welte T, Timmer MSM, Stocker BL, Nakanishi Y, Miyamoto T, Yamasaki S, Maus UA. C-type lectin Mincle recognizes glucosyl-diacylglycerol of Streptococcus pneumoniae and plays a protective role in pneumococcal pneumonia. PLoS Pathog 2016; 12(12): e1006038. doi: 10.1371/journal.ppat.1006038. (Impact Factor 2016: 7.64)

 

Jonigk D, Rath B, Borchert P, Braubach P, Maegel L, Izykowski N, Warnecke G, Sommer W, Kreipe H, Blach R, Anklamm A, Haverich A, Eder M, Stadler M, Welte T, Gottlieb J, Kuehnel M, Laenger F. Comparative Analysis of Morphological and Molecular Motifs in Bronchiolitis Obliterans and Alveolar Fibroelastosis after Lung and Stem Cell Transplantation. J Pathol Clin Res 2016; 3(1): 17-28. doi: 10.1002/cjp2.60. (Impact Factor 2015: 7.381)

 

Christgen M, van Luttikhuizen JL, Raap M, Braubach P, Schmidt L, Jonigk D, Feuerhake F, Lehmann U, Schlegelberger B, Kreipe HH, Steinemann D. Precise ERBB2 copy number assessment in breast cancer by means of molecular inversion probe array analysis. Oncotarget 2016; 7(50): 82733-82740. doi: 10.18632/oncotarget.12421. (Impact Factor 2014: 6.359)

 

Weissinger E, Human C, Metzger J, Hambach L, Wolff D, Greinix H, Dickinson A, Mullen W, Jonigk D, Kuzmina Z, Kreipe H, Schweier P, Boehm O, Turuchanow I, Ihlenburg-Schwarz D, Raad J, Durban A, Schiemann M, Koenecke C, Diedrich H, Holler E, Beutel G, Krauter J, Ganser A, Stadler M. The proteome pattern cGvHD_MS14 allows early and accurate prediction of chronic GvHD after allogeneic stem cell transplantation. Leukemia 2016; 31(3): 654-662. doi: 10.1038/leu.2016.259. (Impact Factor 2015: 4.33)

 

Poehnert D, Grethe L, Maegel L, Jonigk D, Lippmann T, Kaltenbirn A, Schrem H, Klempnauer J, Winny M. Evaluation of the Effectiveness of Peritoneal Adhesion Prevention Devices in a Rat Model. Int J Med Sci 2016; 13(7): 524-32. doi: 10.7150/ijms.15167. (Impact Factor 2015: 2.59)

 

Winny M, Maegel L, Grethe LV, Jonigk D, Borchert P, Kaltenborn A, Schrem H, Klempnauer J, Poehnert D. Treatment of de-peritonealized intestine with 4DryField® PH prevents adhesions between non-resorbable intra-peritoneal hernia mesh and bowel. Am J Transl Res 2016; 8(12): 5706-5714. (Impact Factor 2016: 2.829)

 

Dabral S, Tian X, Kojonazarov B, Savai R, Ghofrani HA, Weissmann N, Florio M, Sun J, Jonigk D, Maegel L, Grimminger F, Seeger W, Savai Pullamsetti S, Schermuly RT. Notch1 signalling regulates endothelial proliferation and apoptosis in pulmonary arterial hypertension. Eur Respir J 2016; 48(4): 1137-1149. doi: 10.1183/13993003.00773-2015. (Impact Factor 2015: 7.636)

 

Siemeni T, Knoefel AK, Madrahimov N, Sommer W, Avsar M, Salman J, Ius F, Frank N, Buechler G, Jonigk D, Jansson K, Maus U, Tudorache I, Falk CS, Haverich A, Warnecke G. In Vivo Development of Transplant Arteriosclerosis in Humanized Mice Reflects Alloantigen Recognition and Periphal Treg Phenotype of Lung Transplant Recipients. Am J Transplant 2016; 16(11): 3150-3162. doi: 10.1111/ajt.13905. (Impact Factor 2015: 4.21)

 

Izykowski N, Kuehnel M, Hussein K, Mitschke K, Gunn M, Janciauskiene S, Haverich A, Warnecke G, Laenger F, Maus U, Jonigk D. Organizing Pneumonia in Mice and Men. J Transl Med 2016; 14(1): 169. doi: 10.1186/s12967-016-0933-6. (Impact Factor 2015: 3.93)

 

Winny M, Maegel L, Grethe L, Lippmann T, Jonigk D, Schrem H, Kaltenborn A, Klempnauer J, Poehnert D. Adhesion Prevention Efficacy of Composite Meshes Parietex®, Proceed® and 4DryField® PH Covered Polypropylene Meshes in an IPOM Rat Model. Int J Med Sci 2016; 13(12): 936-941. (Impact Factor 2016: 2.399)

 

Krueger M, Zinne N, Biancosino C, Hoeffler K, Rajab TK, Waldmann KH, Jonigk D, Avsar M, Haverich A, Hoeltig D. Porcine pulmonary auto-transplantation for ex vivo therapy as a model for new treatment strategies. Interact Cariovasc Thorac Surg 2016; 23(3): 358-66. doi: 10.1093/icvts/ivw160. (Impact Factor 2015: 1.155)

 

Kellner M, Heidrich M, Lorbeer RA, Antonopoulos GC, Knudsen L, Wrede C, Izykowski N, Grothausmann R, Jonigk D, Ochs M, Ripken T, Kühnel MP, Meyer H. A combined method for correlative 3D imaging of biological samples from macro to nano scale. Sci Rep 2016; 6: 35606. doi: 10.1038/srep35606. (Impact Factor 2016: 4.259)

 

Gren ST, Janciauskiene S, Sandeep S, Jonigk D, Kvist PH, Gerwien JG, Hakansson K, Grip O. The protease inhibitor cystatin C down-regulates the release of IL-β and TNF-α in lipopolysaccharide activated monocytes. J Leukoc Biol 2016; 100(4): 811-822. (Impact Factor 2015: 4.289)

 

Winny M, Grethe L, Maegel L, Jonigk D, Lippmann T, Klempnauer J, Poehnert D. Impairment of the Peritoneal Surface as a Decisive Factor for Intestinal Adhesions in Intraperitoneal Onlay Mesh Surgery - Introducing a New Rat Model. Int J Med Sci 2016; 13(2): 108-12. doi: 10.7150/ijms.14056. (Impact Factor 2015: 2.003)

 

Rafikova O, Rafikov R, Kangath A, Qu N, Aggarwal S, Sharma S, Desai J, Fields T, Ludewig B, Yuan JX, Jonigk D, Black SM. Redox regulation of epidermal growth factor receptor signaling during the development of pulmonary hypertension. Free Radic Biol Med 2016; 95: 96-111. doi: 10.1016/j.freeradbiomed.2016.02.029 (Impact Factor 2015: 5.736)

 

Leo F, Bartels S, Maegel L, Framke T, Buesche G, Jonigk D, Christgen M, Lehmann U, Kreipe H. Prognostic factors in the myoepithelial-like spindle cell type of metaplastic breast cancer. Virchows Arch 2016; 469(2): 191-201. doi: 10.1007/s00428-016-1950-9. (Impact Factor 2013: 2.676)

 

Olsson KM, Olle S, Fuge J, Welte T, Hoeper MM, Lerch C, Maegel L, Haller H, Jonigk D, Schiffer L. CXCL13 in idiopathic pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension. Respir Res 2016; 17: 21. doi: 10.1186/s12931-016-0336-5. (Impact Factor 2015: 3.093)

 

Derlin T, Jonigk D, Bauersachs J, Bengel F. Molecular imaging of chemokine receptor CXCR4 in non-small cell lung cancer using 68Ga-Pentixafor PET/CT: comparison with 18F-FDG. Clin Nucl Med 2016; 41(4): e204-5. doi: 10.1097/RLU.0000000000001092. (Impact Factor 2014: 3.931)

 

Avsar M, Jansson K, Sommer W, Kruse B, Thissen S, Dreckmann K, Knoefel AK, Salman J, Hafer C, Hecker J, Buechler G, Karstens JH, Jonigk D, Länger F, Kaever V, Falk CS, Hewicker-Trautwein M, Ungefroren H, Haverich A, Strüber M, Warnecke G. Augmentation of Transient Donor Cell Chimerism and Alloantigen-Specific Regulation of Lung Transplants in Miniature Swine. Am J Transplant 2016; 16(5): 1371-82. doi: 10.1111/ajt.13629. (Impact Factor 2014: 5.683)

 

Schieck M, Schouten JP, Michel S, Suttner K, Toncheva AA, Gaertner V, Illig T, Lipinski S, Franke A, Klintschar M, Kalayci O, Sahiner UM, Birben E, Melén E, Pershagen G, Freidin MB, Ogorodova LM, Granell R, Henderson J, Brunekreef B, Smit HA, Vogelberg C, von Berg A, Bufe A, Heinzmann A, Laub O, Rietschel E, Simma B, Genuneit J, Jonigk D, Postma DS, Koppelman GH, Vonk JM, Timens W, Boezen HM, Kabesch M. Doublesex and mab-3 related transcription factor 1 (DMRT1) is a sex-specific genetic determinant of childhood onset asthma and is expressed in testis and macrophages. J Allergy Clin Immun 2016; 138(2): 421-31. doi: 10.1016/j.jaci.2015.12.1305. (Impact Factor 2014: 11.476)

 

Watermann I, Schmitt B, Stellmacher F, Müller J, Gaber R, Kugler C, Reinmuth N, Huber RM, Thomas M, Zabel P, Rabe KF, Jonigk D, Warth A, Vollmer E, Reck M, Goldmann T. Improved diagnostics targeting c-MET in non-small cell lung cancer: expression, amplification and activation? Diagn Pathol 2015; 10: 130. doi: 10.1186/s13000-015-0362-5. (Impact Factor 2014: 2.597)

 

Jonigk D, Izykowski N, Rische J, Braubach P, Kühnel M, Warnecke G, Lippmann T, Kreipe H, Haverich A, Welte T, Gottlieb J, Laenger F. Molecular Profiling in Lung Biopsies of Human Pulmonary Allografts to Predict Chronic Lung Allograft Dysfunction. Am J Pathol 2015; 185(12): 3178-88. doi: 10.1016/j.ajpath.2015.08.016. (Impact Factor 2014: 4.591)

 

Zhang R, Bures M, Höffler HK, Jonigk D, Haverich A, Krüger M. In Vitro Lung Model Assessing the Efficacy of Surgical Sealants in Treating Alveolar Air Leaks. J Invest Surg 2015; 28(6): 323-7. doi: 10.3109/08941939.2015.1010023. (Impact Factor 2014: 1.158)

 

Fuehner T, Clajus C, Fuge J, Jonigk D, Welte T, Haverich A, Greer M, Gottlieb J. Lung Transplantation after Endoscopic Lung Volume Reduction. Respiration 2015; 90(3): 243-50. doi: 10.1159/000434685. (Impact Factor 2014: 2.593)

 

Kellner M, Wehling J, Warnecke G, Heidrich M, Izykowski N, Vogel-Claussen J, Lorbeer RA, Antonopoulos G, Janciauskiene S, Grothausmann R, Knudsen L, Ripken T, Meyer H, Kreipe H, Ochs M, Jonigk D*, Kühnel MP*. Correlating 3D morphology with molecular pathology: fibrotic remodelling in human lung biopsies. Thorax 2015; 70(12): 1197-8. doi: 10.1136/thoraxjnl-2015-207131. (Impact-Factor 2014: 8.290)

*shared last author

 

Stammler A, Hau T, Bhushan S, Meinhardt A, Jonigk D, Lippmann T, Pilatz A, Schneider-Hüther I, Middendorff R. Epididymitis: ascending infection restricted by segmental boundaries. Hum Reprod 2015; 30(7): 1557-65. doi: 10.1093/humrep/dev112. (Impact Factor 2014: 4.569)

 

Rafikova O, Rafikov R, Meadows ML, Kangath A, Jonigk D, Black SM. The sexual dimorphism associated with pulmonary hypertension corresponds to a fibrotic phenotype. Pulm Circ 2015; 5(1): 184-97. doi: 10.1086/679724. (Impact Factor 2014: 2.66)

 

Knippenberg S, Ueberberg B, Maus R, Bohling J, Ding N, Tort Tarres M, Hoymann HG, Jonigk D, Izykowski N, Paton JC, Ogunniyi AD, Lindig S, Bauer M, Welte T, Seeger W, Guenther A, Sisson TH, Gauldie J, Kolb M, Maus UA. Streptococcus pneumoniae triggers progression of pulmonary fibrosis through pneumolysin. Thorax 2015; 70(7): 636-46. doi: 10.1136/thoraxjnl-2014-206420. (Impact Factor 2014: 8.290)

 

Sommer W, Knöfel AK, Madrahimov N, Avsar M, Jonigk D, Salman J, Dreckmann K, Jansson K, Haverich A, Warnecke G. Allogeneic CD4+CD25 high T cells regulate obliterative bronchiolitis of heterotopic bronchus allograft in both porcinized and humanized mouse models. Transplantation 2015; 99(3): 482-91. doi: 10.1097/TP.0000000000000632. (Impact Factor 2014: 3.781)

 

Sommer W, Knöfel AK, Izykowski N, Oldhafer F, Avsar M, Jonigk D, Warnecke G, Haverich A. Physical exercise reduces transplant arteriosclerosis in a mouse aorta transplantation model. J Thorac Cardiovasc Surg 2015; 149(1): 330-7. doi: 10.1016/j.jtcvs.2014.10.029. (Impact Factor 2014: 3.526)

 

Behler F, Maus R, Bohling J, Knippenberg S, Kirchhof G, Nagata M, Jonigk D, Izykowski N, Mägel L, Welte T, Yamasaki S, Maus UA. Macrophage-inducible C-type lectin Mincle expressing dendritic cells contribute to control splenic Mycobacterium bovis BCG infection in mice. Infect Immun 2015; 83(1): 184-96. doi: 10.1128/IAI.02500-14. (Impact Factor 2014: 4.074)

 

Zhang R, Bures M, Höffler K, Jonigk D, Haverich A, Krueger M. In vitro comparison of two widely used surgical sealants for treating alveolar air leak. Thorac Cardiovasc Surg 2014; 62(8): 705-9. doi: 10.1055/s-0034-1389272 (Impact Factor 2013: 0.925)

 

Abbas M, Ploch EM, Wehling J, Schipper E, Janciauskiene S, Kreipe HH, Jonigk D. α-Methylacyl-coenzyme A racemase (AMACR, p504s) is a marker to distinguish malignant melanomas from dysplastic nevi and melanocytic nevi. Tumor Biol 2014; 35(12): 12015-20. doi: 10.1007/s13277-014-2500-1. (Impact Factor 2013: 2.518)

 

Hussein K, Rath B, Ludewig B, Kreipe H, Jonigk D. Clinico-pathological characteristics of different types of immunodeficiency-associated smooth muscle tumours. Eur J Cancer 2014; 50(14): 2417-24. doi: 10.1016/j.ejca.2014.06.006. (Impact Factor 2013: 5.061)

 

Barman S, Chen F, Su Y, Dimitropoulou C, Wang Y, Catravas J, Han W, Orfi L, Szantai-Kis C, Keri G, Szabadkai I, Barabutis N, Black S, Jonigk D, Giannis A, Asmis R, Stepp D, Ramesh G, Rafikova O, Rafikov R, Fulton D. NADPH oxidase 4 is expressed in pulmonary artery adventitia and contributes to hypertensive vascular remodeling. Arterioscler Thromb Vasc Bio 2014; 34(8): 1704-15. doi: 10.1161/ATVBAHA.114.303848. (Impact Factor 2013: 6.338)

 

Alam S, Li Z, Atkinson C, Jonigk D, Janciauskiene S, Mahadeva R. Z alpha-1 antitrypsin confers a pro-inflammatory phenotype that contributes to COPD. Am J Respir Crit Care Med 2014; 189(8): 909-31. doi: 10.1164/rccm.201308-1458OC. (Impact Factor 2013: 11.041)

 

Liessem S, Winkens W, Jonigk D, Wasielewski R, Fisseler-Eckhoff A, Rüschoff J, Kreipe HH. Determination of tumor biological parameters in breast cancer: round robin testing for quality assurance. Pathologe 2014; 35(1):61-71. doi: 10.1007/s00292-013-1837-3. (Impact Factor 2013: 0.621)

 

Aggarwal S, Gross CM, Rafikov R, Kumar S, Fineman JR, Ludewig B, Jonigk D, Black SM. Nitration of tyrosine 247 inhibits protein kinase G-1α activity by attenuating cyclic guanosine monophosphate binding. J Biol Chem 2014; 289(11): 7948-61. doi: 10.1074/jbc.M113.534313. (Impact Factor 2013: 4.651)

 

Abbas M, Salem J, Stucki-Koch A, Rickmann M, Grünwald V, Herrmann T, Jonigk D, Kreipe H, Hussein K. Expression of angiogenic factors is increased in metastasised renal cell carcinomas. Virchows Arch 2014; 464(2): 197-202. doi: 10.1007/s00428-013-1529-7. (Impact Factor 2013: 2.676)

 

Jonigk D, Izykowski N, Maegel L, Schormann E, Ludewig B, Kreipe H, Hussein K. Tumour angiogenesis in Epstein-Barr virus-associated post-transplant smooth muscle tumours. Clin Sarcoma Res 2014; 4(1): 1. doi: 10.1186/2045-3329-4-1. (Impact Factor 2013: 5.2)

 

Atanasova S, Hirschburger M, Jonigk D, Obert M, Petri K, Evers A, Hecker A, Schmitz J, Kaufmann A, Wilhelm J, Chakraborty T, Warnecke G, Gottlieb J, Padberg W, Grau V. A relevant experimental model for human bronchiolitis obliterans syndrome. J Heart Lung Transplant 2013; 32(11): 1131-9. doi: 10.1016/j.healun.2013.07.016. (Impact Factor 2013: 5.112)

 

Hussein K, Maecker-Kolhoff B, Donnerstag F, Laenger F, Kreipe H, Jonigk D. Epstein-barr virus-associated smooth muscle tumours after transplantation, infection with human immunodeficiency virus and congenital immunodeficiency syndromes. Pathobiology 2013; 80(6): 297-301. doi: 10.1159/000351326. (Impact Factor 2013: 1.948)

 

Jonigk D, Al-Omari M, Maegel L, Müller M, Izykowski N, Hong J, Hong K, Kim SH, Dorsch M, Mahadeva R, Laenger F, Kreipe H, Braun A, Shahaf G, Lewis EC, Welte T, Dinarello CA, Janciauskiene S. Anti-inflammatory and immunomodulatory properties of α1-antitrypsin without inhibition of elastase. Proc Natl Acad Sci USA 2013; 110(37): 15007-12. doi: 10.1073/pnas.1309648110. (Impact Factor 2013: 9.737)

 

Neuhaus V, Schwarz K, Klee A, Seehase S, Förster C, Pfennig O, Jonigk D, Fieguth HG, Koch W, Warnecke G, Yusibov V, Sewald K, Braun A. Functional testing of an inhalable nanoparticle based influenza vaccine using a human precision cut lung slice technique. PLoS ONE 2013; 8(8): e71728. doi: 10.1371/journal.pone.0071728. (Impact Factor 2013: 3.73)

 

Jonigk D, Izykowski N, Maegel L, Schormann E, Maecker-Kolhoff B, Laenger F, Kreipe H, Hussein K. MicroRNA expression in Epstein-Barr virus-associated post-transplant smooth muscle tumours is related to leiomyomatous phenotype. Clin Sarcoma Res 2013; 3(1): 9. doi: 10.1186/2045-3329-3-9. (Impact Factor 2013: 5.2)

 

V Laffert M, Warth A, Penzel R, Schirmacher P, Jonigk D, Kreipe H, Schildhaus HU, Merkelbach-Bruse S, Büttner R, Reu S, Kerler R, Jung A, Kirchner T, Wölfel C, Petersen I, Rodriguez R, Jochum W, Bartsch H, Fisseler-Eckhoff A, Berg E, Lenze D, Dietel M, Hummel M. Anaplastic lymphoma kinase (ALK) gene rearrangement in non-small cell lung cancer (NSCLC): results of a multi-centre ALK-testing. Lung Cancer 2013; 81(2): 200-6. doi: 10.1016/j.lungcan.2013.04.015. (Impact Factor 2013: 3.392)

 

Hauck G, Jonigk D, Göhring G, Kreipe H, Hussein K. Myelofibrosis in Philadelphia chromosome-negative myeloproliferative neoplasms is associated with aberrant karyotypes. Cancer Genet 2013; 206(4): 116-23. doi: 10.1016/j.cancergen.2013.02.002. (Impact Factor 2013: 1.915)

 

Warth A, Fink L, Fisseler-Eckhoff A, Jonigk D, Keller M, Ott G, Rieker RJ, Sinn P, Söder S, Soltermann A, Willenbrock K, Weichert W. Pulmonary Pathology Working Group of the German Society of Pathology. Interobserver agreement of proliferation index (Ki-67) outperforms mitotic count in pulmonary carcinoids. Virchows Arch 2013; 462(5): 507-13. doi: 10.1007/s00428-013-1408-2. (Impact Factor 2013: 2.676)

 

Böer U, Spengler C, Jonigk D, Klingenberg M, Schrimpf C, Lützner S, Harder M, Kreipe HH, Haverich A, Wilhelmi M. Coating decellularized equine carotid arteries with CCN1 improves cellular repopulation, local biocompatibility, and immune response in sheep. Tissue Eng Part A 2013; 19(15-16): 1829-42. doi: 10.1089/ten.TEA.2012.0558. (Impact Factor 2013: 4.065)

 

Böer U, Spengler C, Klingenberg M, Jonigk D, Harder M, Kreipe HH, Haverich A, Wilhelmi M. Cytotoxic effects of polyphexanide on cellular repopulation and calcification of decellularized equine carotids in vitro and in vivo. Int J Artif Organs 2013; 36(3): 184-94. doi: 10.5301/IJAO.5000182. (Impact Factor 2013: 1.759)

 

Rafikova O, Rafikov R, Kumar S, Sharma S, Aggarwal S, Schneider F, Jonigk D, Black SM, Tofovic SP. Bosentan inhibits oxidative and nitrosative stress and rescues occlusive pulmonary hypertension. Free Radic Biol Med 2013; 56: 28-43. doi: 10.1016/j.freeradbiomed.2012.09.013. (Impact Factor 2013: 5.271)

 

Pilatz A, Altinkilic B, Schormann E, Maegel L, Izykowski N, Becker J, Weidner W, Kreipe H, Jonigk D. Congenital Phimosis With and Without Lichen Sclerosus: Distinct Expression Patterns of Tissue Remodeling-Associated Genes. J Urol 2013; 189(1): 268-74. doi: 10.1016/j.juro.2012.09.010. (Impact Factor 2013: 3.696)

 

Hauck G, Jonigk D, Kreipe H, Hussein K. Simultaneous and sequential concurrent myeloproliferative and lymphoproliferative neoplasms. Acta Haematologica 2012; 129(3): 187-96. doi: 10.1159/000342484. (Impact Factor 2013: 0.894)

 

Neumann D, Beermann S, Maegel L, Jonigk D, Weber-Steffens D, Maennel D, Seifert R. Problems associated with the use of commercial and non-commercial antibodies against the histamine H4-receptor. Naunyn-Schmiedeberg's Archives of Pharmacology. 2012; 385(9): 855-60. doi: 10.1007/s00210-012-0766-7. (Impact Factor 2013: 2.147)

 

Koczulla R*, Jonigk D*, Wolf T, Herr C, Noeske S, Klepetko W, Vogelmeier C, von Neuhoff N, Rische J, Wrenger S, Golpon H, Voswinckel R, Luisetti M, Ferrarotti I, Welte T, Janciauskiene S. Kruppel-like zinc finger proteins in end-stage COPD lungs with and without severe alpha1-antitrypsin deficiency. Orphanet J Rare Dis 2012; 7:29. doi: 10.1186/1750-1172-7-29. (Impact Factor 2013: 4.315)

* shared first author

 

Bockmeyer CL, Maegel L, Janciauskiene S, Rische J, Lehmann U, Maus UA, Nickel N, Haverich A, Hoeper MM, Golpon HA, Kreipe H, Laenger F, Jonigk D. Plexiform vasculopathy of severe pulmonary arterial hypertension and microRNA expression. J Heart Lung Transplant 2012; 31(7): 764-72. doi: 10.1016/j.healun.2012.03.010. (Impact Factor 2013: 5.112)

 

Hadem J, Bockmeyer CL, Lukasz A, Pischke S, Schneider AS, Wedemeyer H, Jonigk D, Manns MP, Kumpers P. Angiopoietin-2 in acute liver failure. Crit Care Med. 2012; 40(5): 1499-505. doi: 10.1097/CCM.0b013e318241e34e. (Impact Factor 2013: 6.124)

 

Jonigk D, Laenger F, Maegel L, Izykowski N, Rische J, Tiede C, Klein C, Maecker-Kolhoff B, Kreipe H, Hussein K. Molecular and Clinicopathological Analysis of Epstein-Barr Virus-Associated Posttransplant Smooth Muscle Tumors. Am J Transplant 2012; 12(7): 1908-17. doi: 10.1111/j.1600-6143.2012.04011.x. (Impact Factor 2013: 6.192)

 

Pilatz A, Altinkilic B, Rusz A, Izykowski N, Traenkenschuh W, Rische J, Lehmann U, Herbst C, Maegel L, Becker J, Weidner W, Jonigk D. Role of human papillomaviruses in persistent and feglucocorticoid-resistant juvenile phimosis. J Eur Acad Dermatol Venereol 2012; 27(6): 716-21. doi: 10.1111/j.1468-3083.2012.04542. (Impact Factor 2013: 2.694)

 

Beermann S, Glage S, Jonigk D, Seifert R, Neumann D. Opposite effects of mepyramine on JNJ 7777120-induced amelioration of experimentally induced asthma in mice in sensitization and provocation. PLoS ONE. 2012; 7(1): e30285. doi: 10.1371/journal.pone.0030285. (Impact Factor 2013: 3.73)

 

Nickel N*, Jonigk D*, Kempf T, Bockmeyer CL, Maegel L, Rische J, Laenger F, Lehmann U, Sauer C, Greer M, Welte T, Hoeper MM, Golpon HA. GDF-15 is abundantly expressed in plexiform lesions in patients with pulmonary arterial hypertension and affects proliferation and apoptosis of pulmonary endothelial cells. Respir Res 2011; 12:62. doi: 10.1186/1465-9921-12-62. (Impact Factor 2013: 3.642)

* shared first author

 

Jonigk D*, Golpon H*, Bockmeyer CL, Maegel L, Hoeper MM, Gottlieb J, Nickel N, Hussein K, Maus U, Lehmann U, Janciauskiene S, Welte T, Haverich A, Rische J, Kreipe H, Laenger F. Plexiform lesions in pulmonary arterial hypertension composition, architecture, and microenvironment. Am J Pathol 2011 179(1): 167-79. doi: 10.1016/j.ajpath.2011.03.040. (Impact 2013: 4.522)

* shared first author

 

Jonigk D, Merk M, Hussein K, Maegel L, Theophile K, Muth M, Lehmann U, Bockmeyer CL, Mengel M, Gottlieb J, Welte T, Haverich A, Golpon H, Kreipe H, Laenger F. Obliterative airway remodeling: molecular evidence for shared pathways in transplanted and native lungs. Am J Pathol 2011; 179(1): 167-79. doi: 10.1016/j.ajpath.2011.03.040. (Impact Factor 2013: 4.522)

 

Al-Omari M, Korenbaum E, Ballmaier M, Lehmann U, Jonigk D, Manstein DJ, Welte T, Mahadeva R, Janciauskiene S. Acute-phase protein alpha1-antitrypsin inhibits neutrophil calpain I and induces random migration. Mol Med 2011 17(9-10): 865-74. doi: 10.2119/molmed.2011.00089 (Impact Factor 2013: 4.469)

 

Traeder J, Jonigk D, Feist H, Brocker V, Laenger F, Kreipe H, Hussein K. Pathological characteristics of a series of rare chronic histiocytic intervillositis of the placenta. Placenta 2010; 31(12): 1116-9. doi: 10.1016/j.placenta.2010.09.012. (Impact Factor 2013: 3.117)

 

Kumpers P, Nickel N, Lukasz A, Golpon H, Westerkamp V, Olsson KM, Jonigk D, Maegel L, Bockmeyer CL, David S, Hoeper MM. Circulating angiopoietins in idiopathic pulmonary arterial hypertension. Eur Heart J 2010; 31(18): 2291-300. doi: 10.1093/eurheartj/ehq226. (Impact Factor 2013: 14.097)

 

Jonigk D, Theophile K, Hussein K, Bock O, Lehmann U, Bockmeyer CL, Gottlieb J, Fischer S, Simon A, Welte T, Maegel L, Kreipe H, Laenger F. Obliterative airway remodelling in transplanted and non-transplanted lungs. Virchows Arch 2010; 457(3): 369-80. doi: 10.1007/s00428-010-0949-x. (Impact Factor 2013: 2.676)

 

Kocks JR, Adler H, Danzer H, Hoffmann K, Jonigk D, Lehmann U, Forster R. Chemokine receptor CCR7 contributes to a rapid and efficient clearance of lytic murine gamma-herpes virus 68 from the lung, whereas bronchus-associated lymphoid tissue harbors virus during latency. J Immunol 2009; 182(11): 6861-9. doi: 10.4049/jimmunol.0801826. (Impact Factor 2013: 5.52)

 

Hussein K, Bock O, Theophile K, Schulz-Bischof K, Porwit A, Schlue J, Jonigk D, Kreipe H. MPLW515L mutation in acute megakaryoblastic leukaemia. Leukemia 2009; 23(5): 852-5. doi: 10.1038/leu.2008.371. (Impact Factor 2013: 10.164)

 

Theophile K, Jonigk D, Kreipe H, Bock O. Amplification of mRNA from laser-microdissected single or clustered cells in formalin-fixed and paraffin-embedded tissues for application in quantitative real-time PCR. Diagn Mol Pathol 2008; 17(2): 101-6. doi: 10.1097/PDM.0b013e318163f26e. (Impact Factor 2013: 1.861)

 

Stuht S, Gwinner W, Franz I, Schwarz A, Jonigk D, Kreipe H, Kerjaschki D, Haller H, Mengel M. Lymphatic neoangiogenesis in human renal allografts: results from sequential protocol biopsies. Am J Transplant 2007; 7(2): 377-84. doi: 10.1111/j.1600-6143.2006.01638.x. (Impact Factor 2013: 6.192)

 

Jonigk D, Lehmann U, Stuht S, Wilhelmi M, Haverich A, Kreipe H, Mengel M. Recipient-derived neoangiogenesis of arterioles and lymphatics in quilty lesions of cardiac allografts. Transplantation 2007; 84(10): 1335-42. doi: 10.1097/01.tp.0000287458.72440.75. (Impact Factor 2013: 3.781)

 

Mengel M, Jonigk D, Wilkens L, Radermacher J, von Wasielewski R, Lehmann U, Haller H, Mihatsch M, Kreipe H. Chimerism of metanephric adenoma but not of carcinoma in kidney transplants. Am J Pathol 2004; 165(6): 2079-85. doi: 10.1016/S0002-9440(10)63258-0. (Impact Factor 2013: 4.522)

 

Mengel M, Jonigk D, Marwedel M, Kleeberger W, Bredt M, Bock O, Lehmann U, Gwinner W, Haller H, Kreipe H. Tubular chimerism occurs regularly in renal allografts and is not correlated to outcome. J Am Soc Nephrol 2004; 15(4): 978-86. doi: 10.1097/01.ASN.0000120369.92378.54. (Impact Factor 2013: 8.987)        

 

 

Übersichtsartikel – peer-reviewed

 

 

Tzankov A, Jonigk D.  Unlocking the lockdown of science and demystifying COVID-19: howautopsies contribute to our understanding of a deadly pandemic. Virchows Arch. 2020 Jul 9:1-3. doi: 10.1007/s00428-020-02887-5. Online ahead of print. PMID: 32648040 (Impact Factor 2019: 2,920)

 

Greimelmaier K, Wohlschläger J, Probst A, Hager T, Wardelmann E, Werlein C,  Jonigk D, Müller KM. Mesotheliale Proliferate der Tunica vaginalis testis. Pathologe. 2020 May 29. doi: 10.1007/s00292-020-00797-6. Online ahead of print PMID: 32472158 (Impact Factor 2018/2019: 0.28)

 

Behr J, Günther A, Bonella F, Dinkel J, Fink L, Geiser T, Geißler K, Gläser S, Handzhhiev S, Jonigk D, Koschel D, Kreuter M, Leuschner G, Markart P, Prasse A, Schönfeld N, Schupp JC, Sitter H, Müller-Quernheim J, Costabel U. S2K Leitlinie zur Diagnostik der Idiopathischen Lungenfibrose. Pneumologie. 2020 May;74(5):e1. doi: 10.1055/a-1179-2905. Epub 2020 May 18.Pneumologie. 2020. PMID: 32422671 (Impact Factor: 0.840)

 

Greer M, Werlein C, Jonigk D. Surveillance for acute cellular rejection after lung transplantation. Ann Transl Med. 2020 Mar;8(6):410. doi: 10.21037/atm.2020.02.127.Ann Transl Med. 2020. PMID: 32355854 (Impact Factor 2018: 3.689)

 

Verleden S, Von der Thusen J, Roux A, Brouwer E, Braubach P, Kühnel M, Länger F, Jonigk D. When tissue is the issue: a histological review of chronic lung allograft dysfunction. Am J Transplant, 2020 Mar 17. doi: 10.1111/ajt.15864 (Impact Factor 2018: 7.163)

 

Bogaard HJ, Legchenko E, Ackermann M, Kühnel MP, Jonigk DD, Chaudhary KR, Sun X, Stewart DJ, Hansmann G. Reply to: Early Disruption of VEGF Receptor Signalling and the Risk for Adult Emphysema. Am J Respir Crit Care Med. 2019 Nov 26. doi: 10.1164/rccm.201910-1983LE (Impact Factor: 16.49)

 

Laenger F, Stark H, Braubach P, Ackermann A, Hussein K, Teiken K, Maegel, Kuehnel M, Jonigk D. Injury patterns in interstitial lung diseases. Pathologe 2018; 39(Suppl 2): 262-271. doi: 10.1007/s00292-018-0503-1. (Impact Factor 2013: 0.621)

 

Wohlschlaeger J, Laenger F, Gottlieb J, Thomas Hager T, Seidel A, Jonigk D. Lungentransplantation: Histomorphologische Diagnostik und klinische Aspekte. Der Pathologe 2019; 40(3): 281-291. doi: 10.1007/s00292-019-0598-z. (Impact Factor 2013: 0.621)

 

Olschewski A, Berghausen EM, Eichstaedt CA, Fleischmann BK, Grünig E, Grünig G, Hansmann G, Harbaum L, Hennigs JK, Jonigk D, Kübler WM, Kwapiszewska G, Pullamsetti SS, Stacher E, Weissmann N, Wenzel D, Schermuly RT. Pathobiologie, Pathologie und Genetik der pulmonalen Hypertonie: Empfehlungen der Kölner Konsensus-Konferenz 2016 [Pathobiology, pathology and genetics of pulmonary hypertension: Recommendations of the Cologne Consensus Conference 2016]. Dtsch med Wochenschr 2016; 141(S 01): S4-S9. doi: 10.1055/s-0042-114520. (Impact Factor 2015: 0.162)

 

Kuehnel M, Maegel L, Vogel-Claussen J, Robertus JL, Jonigk D. Airway remodelling in the transplanted lung. Cell and Tissue Research. 2017; 367(3):663-675. doi: 10.1007/s00441-016-2529-0. (Impact Factor 2017: 3.043)

 

Hussein K, Brix A, Matin E, Jonigk D. Tod am Nil. Ärzte Woche 2015 (Impact Factor 2015: n.a.)

 

Giagnorio R, Deindl P, Maiweg E, Ehrenberg K, Jonigk D, Hansmann G. Persistierende pulmonale Hypertonie des Neugeborenen und chronisch progressive pulmonale Hypertonie im ersten Lebensjahr. Kinder- und Jugendmedizin 2015; 15(05): 362-373.doi: 10.1055/s-0038-1629283. (Impact Factor 2015: n.a.)

 

Jonigk D. Aberrierender reparativer Gewebeumbau: Histopathologie und Molekularpathologie [Aberrant reparative tissue remodeling: Histopathology and molecular pathology]. Pathologe 2014; 35 Suppl 2: 254-63. doi: 10.1007/s00292-014-1955-6. (Impact Factor 2013: 0.621)

 

Hussein K, Brix A, Matin E, Jonigk D. Tutanchamun: Evidenzbasierte Paleopathologie versus "Fluch des Pharao". Pathologe 2014; 36(2): 186-92. doi: 10.1007/s00292-014-1940-0. (Impact Factor 2014: 0.406)

 

Jonigk D, Hoeper MM, Kreipe H, Laenger F. Histopathological aspects of pulmonary hypertension. Pathologe 2012; 33(3): 183-91. doi: 10.1007/s00292-011-1560-x. (Impact Factor 2013: 0.621)

 

Wohlschlager J, Sommerwerck U, Jonigk D, Rische J, Baba HA, Mueller KM. Lung transplantation and rejection. Basic principles, clinical aspects and histomorphology. Pathologe 2011; 32(2): 104-12. doi: 10.1007/s00292-010-1403-1. (Impact Factor 2011: 0.669)

 

Janciauskiene S, Ferrarotti I, Laenger F, Jonigk D, Luisetti M. Clinical utility gene card for: alpha-1-antitrypsin deficiency. Eur J Hum Genet 2011; 19(5). doi: 10.1038/ejhg.2010.246. (Impact Factor 2013: 4.319)

 

Soudah B, Schirakowski A, Jonigk D. Zytologie der Lunge und Differentialdiagnose der Lungentumoren. Lungentumoren Cyto-Info 2011; 30(3): 75-81 (Impact Factor 2015: n.a.)

 

 

Buchkapitel – peer-reviewed und PubMed gelistet

 

1.            Bockmeyer CL, Jonigk D, Kreipe H, Lehmann U. MicroRNA profiling using RNA from microdissected immunostained tissue. Methods Mol Biol 2011

 

2.            Jonigk D, Modde F, Bockmeyer CL, Becker JU, Lehmann U. Optimized RNA extraction from non-deparaffinized, laser-microdissected material. Methods Mol Biol 2011

 

Wissenschaftliche Präsentationen

 

 

Jonigk D. COVID-19-Auswirkungen auf die Lungen. COVID-19 Meeting 2020, Robert Koch Institut, Berlin.

 

Böhlen S, Konzok S, Sonntag F, Braubach P, Jonigk D, Warnecke G, Fieguth HG, Sewald K, Braun A, Dehmel S. Novel patient-specific immunocompetent ex-vivo models to study early metastasis and different cancer treatment approaches. DgfI Herbstschule 2020, Merseburg.

 

Schmitz J, Stark H, Bartels S, Jonigk D, Halloran PF, Einecke G, Braesen JH. Molecular analysis of renal graft biopsies: comparing the Edmonton Molecular Microscope with the NanoString Human Organ Transplant Panel. ASN Kidney Week 2020, Denver, USA.

 

Schmitz J, Senger S, Khalifa AA, Stark H, Jonigk D, Pape L, Braesen JH. Immunohistochemical and molecular characterization of immune cells in pediatric renal allografts: Mononuclear phagocytes correlate with rejection, re-transplantation, graft function and fibrosis. ASN Kidney Week 2020, Denver, USA.

 

Neubert L, Borchert P, Stark H, Höfer A, Vogel-Claussen J, Warnecke G, Eubel H, Kuenzler P, Kreipe HH, Höper M, Kuehnel M, Jonigk D. Molecular Profiling of Pulmonary Vascular Remodeling in Chronic Pulmonary Disease. DGP 2020, Berlin.

 

Jonigk D. Covid-19-and the lung. DGP 2020, Berlin.

 

Schmitz J, Stark H, Bartels S, Jonigk D, Halloran PF, Einecke G, Bräsen JH. Molecular analysis of renal transplant biopsies comparing the edmonton molecular microscope with the nanostring human organ transplant panel. DTG Tagung 2020, Köln.

 

Schmitz J, Stark H, Bartels S, Jonigk D, Halloran PF, Einecke G, Bräsen JH. Molecular analysis of renal transplant biopsies comparing the edmonton molecular microscope with the nanostring human organ transplant panel. ESP/IAP 2020, Glasgow Schottland.

 

Große G, Falk C, Kühnel MP, Jonigk D, Lichtinghagen R, Wilhelmi M, Neubert L, Schuppner R, Gabriel MM, Schrimpf C, Stauss R, Weißenborn K. Systemic cytokine network patterns in symptomatic and asymptomatic carotid artery stenosis. ESO-WSO 2020, Wien 2020.

 

Danov O, Boehlen S, Obernolte H, Knebel J, Ritter D, Braubach P, Jonigk D, Braun A, Wronski S, Sewald K. Acute cigarette smoke exposure suppresses antiviral immune response to influenza infection in human precision-cut lung slices. ECCMID 2020, Paris.

 

Endres A, Schubert R, Braubach P, Jonigk D, Hogardt M, Boland H, Rohde G, Bellinghausen C. Pseudomonas aeruginosa influences the inflammatory response of primary bronchial epithelial cells to rhinovirus infection. ERS 2020 Wien.

 

Khan P, Roux J, Savic S, Knudsen L, Jonigk D, Kuehnel MP, Gazdhar A, Geiser T, Tamm M, Hostettler KE. Fibrosis-specific stem-like cells in peripheral IPF lung: Characteristics and potential role. ERS 2020 Wien.

 

Theobald V, Grünig E, Benjamin N, Egenlauf B, Gall H, Halank M, Harutyunova S, Hoeper M, Jonigk D, Schneider M, Seyfahrt HJ, Richtmann S, Xanthouli P, Muckenthaler MU, Eichstaedt CA. Association between BMPR2 mutations and iron metabolism in pulmonary arterial hypertension patients. DZL 2020 Travemünde, DGP 2020 Berlin.
 

Endres A, Bellinghausen C, Hogardt M, Schubert R, Braubach P, Jonigk D, Rohde G. Pseudomonas aeruginosa influences the susceptibility and changes the inflammatory response of primary bronchial epithelial cells (pBECS) to rhinovirus infection. ECFS 2020, Lyon France.

 

Obernolte H,  Rade M, Reiche K, Ritter D, Knebel J, Reamon-Büttner SM, Niehof M, Braubach P, Jonigk D, Warnecke G, Zardo P, Fieguth HG, Pfennig O, Braun A, Sewald K. Cigarette smoke exposure of fresh human lung tissue of the lower respiratory tract shows early regulation of differentially expressed genes identified in emphysema. Models of Lung Disease 2020, Hannover.

 

Polzer M, Pasternack H, Kümpers C, Lazar-Karsten P, Kuehnel M, Jonigk D, Busch H, Gemoll T, Perner S, Kirfel J. Comparative analysis of expression profiles in primary lung adenocarcinomas and matched metastases. DGP 2020, Berlin.

 

Grosse GM, Stauss RD, Neubert L, Falk CS, Jonigk D, Kühnel MP, Gabriel MM, Schuppner R, Lichtinghagen R, Wilhelmi M, Weissenborn K, Schrimpf C. Systemic cytokine network patterns in symptomatic and asymptomatic carotid artery stenosis. ESOC 2020, Vienna.

 

Jonigk D, Stark H, Neubert L, Schubert S, Borchert P, Linz F, Wagner WL, Stiller W, Wielpütz M, Hoefer A, Haverich A, Mentzer SJ, Shah HR, Welte T, Kuehnel M, Ackermann M. Morphomolecular motifs of pulmonary neoangiogenesis in interstitial lung diseases. ATS 2020, Philadelphia.

 

Kuehnel M, Plucinsky E, Stark H, Haverich A, Shah HR, Welte T, Jonigk D. Pollution particle analysis from idiopathic pulmonary fibrosis lungs and their effect on macrophages. ATS 2020, Philadelphia.

 

Engel B, Höfer A, Jonigk D, Hartleben B, Manns MP, Jäckel E, Taubert R. Antibodies against huntingtin interacting protein 1-related protein are more prevalent in patients with antibody mediated rejection after liver transplantation. EASL-ILC 2020, London.

 

Derben FC, Engel B, Hartl J, Jonigk D, Geffers R, Lohse AW, Manns MP, Schramm C, Jaeckel E, Taubert R. Distinct intrahepatic molecular signature between relapse and sustained remission of autoimmune hepatitis before initiation of immunosuppression withdrawal. EASL-ILC 2020, London.

 

Höfer A, Werlein C, Volk V, Feuerhake F, Kühnel M, Jonigk D. Multiplex Immunohistochemistry as a new tool to analyze cell composition of ILDs. DZL Annual Meeting 2020, Travemünde.

 

Hesse C, Wollin SL, Leeming DJ, Sand JMB, Rønnow SR, Konzok S, Niehof M, Braubach P, Jonigk D, Kühnel M, Warnecke G, Pfennig O, Fieguth H-G, Braun A, Sewald K. Nintedanib mediates effective modulation of relevant pro-fibrotic biomarkers ex vivo. DZL Annual Meeting 2020, Travemünde.

 

Beneke V, Cleeves S,  Grahl N, Danov O, Führing J, Konzok S, Braubach P, Jonigk D, Warnecke G, Zardo P, Wilkens L, Fieguth H-G, Braun A, Sewald K, Häußler S,  Wronski S. Pseudomonas aeruginosa flagellin and UGP are determinants of bacterial virulence in an ex vivo model of lung infection. DGP Herbsttagung 2019, Berlin.

 

Kreutzer FP, Meinecke A, Mitzka S, Schmidt K, Perbellini F, Beneke V, Konzok S, Hesse C, Sewald K, Jonigk D, Warnecke G, Terracciano CM, Fiedler J, Thum T.  Treatment of cardiac fibrosis with anti-proliferative small molecules. 86. Annual Meeting DGK 2020, Mannheim.

 

Theobald V, Grünig E, Benjamin N, Egenlauf B, Gall H, Halank M, Harutyunova S, Hoeper M, Jonigk D, Seyfahrt HJ, Xanthouli P, Muckenthale MU, Eichstaedt CA. Association between BMPR2 mutations and iron metabolism in pulmonary arterial hypertension patients. 86. Annual Meeting DGK 2020, Mannheim.

 

Khan P, Roux J, Savic  S, Knudsen L, Jonigk D, Kuehnel MP, Gazdhar A, Geiser T, Tamm M, Hostettler KE. Fibrosis specific KRT5+ progenitor cells in peripheral IPF lung: Characteristics and potential role. ATS conference 2020, Philadelphia.

 

Beneke V, Grahl N, Danov O, Konzok S, Braubach P, Jonigk D, Warnecke G, Pfennig O, Fieguth HG, Braun A, Sewald K, Häußler S, Wronski S. Pseudomonas aeruginosa flagellin modulates the immune response in ex vivo lung tissue slices. ERS Congress 2019, Madrid.

 

Mischak-Weissinger E, Metzger, Schleuning M, Schmid C, Messinger D, Beutel G, Wagner E, Schetelig J, Baurmann H, Rank A, Stoelzl F, Schaefer-Eckart K, Bethge W, Harsdorf S, Bunjes D, Heidenreich D, Klein S, Holler E, Kreipe H, Jonigk D, Tueruechanow I, Raad, Papkalla, Vdleyen, Iyashamwi, Ehrlich S, Krauter J, Stadler M, Ganser A. Proteomic monitoring and pre-emptive therapy of patients with acute GVHD: results from a prospective, randomized, placebo-controlled, multicentre pre-GVHD trial. COSTEM Congress 2019, Berlin.

 

Theobald V, Benjamin N, Egenlauf B, Gall H, Grünig E, Halank M, Harutyunova S, Hoeper M, Jonigk D, Seyfahrt HJ, Xanthouli P, Muckenthaler M, Eichstaedt C.A. Association between BMPR2 mutations and iron metabolism in pulmonary arterial hypertension patients. DGP Kongress 2020, Leibzig.

 

Länger F, Seidel A, Warnecke G, Gottlieb J, Werlein C, Jonigk D. Histomorphology and molecular mechanisms in acute and chronic lung allograft dysfunction. 28. Jahrestagung der Deutschen Transplantationsgesellschaft 2019, Hannover.

 

Höfer A, Taubert R, Hubscher SG, Klawonn F, Jonigk D, Manns M, Verboom M, Hartleben B, Jäckel E, Hallensleben M, Geffers R. Molecular classifier for T cell-mediated and antibody-mediated rejection after liver transplantation. 28. Jahrestagung der Deutschen Transplantationsgesellschaft 2019, Hannover.

 

Bellmas Sanz R, Falk C, Haverich A, Hitz AM, Bläsing KA,  Tudorache I, Jonigk D, Ius F, Warnecke G, Knöfel AK. Donor T and NK cells are derived from the donor lung parenchyma and represent a subset of tissue-resident memory cells. 28. Jahrestagung der Deutschen Transplantationsgesellschaft 2019, Hannover.

 

Höfer A, Verboom M, Hartleben B, Jäckel E, Hallensleben M, Geffers R, Taubert R, Hubscher SG, Klawonn F, Jonigk D, Manns M. Molecular fingerprint of T cell-mediated and antibody-mediated rejection after liver transplantation. 28. Jahrestagung der Deutschen Transplantationsgesellschaft 2019, Hannover.

 

Strauß RD, Große G, Schrimpf C, Weißenborn K, Gabriel MM, Neubert L, Kühnel MP, Jonigk D, Wilhelmi M, Falk C. Die Rolle chemotaktischer Zytokine als mögliche Biomarker zur Identifikation vulnerabler Stenosen der Arteria carotis interna. DGN 2019, Stuttgart.

 

Werlein C, Seidel A, Warnecke G, Gottlieb J, Laenger F, Jonigk D. Histomorphology and molecular mechanisms in acute and chronic lung allograft dysfunction. DTG 2019, Hannover

 

Höfer A, Jonigk D, Hartleben B, Geffers R, Klawonn F, Verboom M, Hallensleben M, S. G. Hübscher SG, Manns MP, Jäckel E, Taubert R. Molecular fingerprint of T cell-mediated

and antibody-mediated rejection after liver transplantation. DTG 2019, Hannover.

 

Pirr S, Bickes MS, Heinemann AS, Fehlhaber B, Halle S, Völlger L, Willers M, Richter M, Böhne C, Albrecht M, Langer  M, Pfeifer S,  Jonigk D, Vieten G, Ure B, von Kaisenberg C, Förster R, von Köckritz-Blickwede M, Hansen G, Viemann D. TNF-α ist essentieller Mediator der postnatalen Einwanderung von Leukozyten in Organe und Grenzflächen. DGKJ 2019, München.

 

Jonigk D. Intersitial lung-diseases – comprehensive approchaes. Böhringer Ingelheim 2019, Ingelheim am Rhein.

 

Jonigk D. Pathologie der EAA. Allergieakademie der DGAKI, Exogene allergische Alveolitis 2019, Königswinter.

 

Stauß RD, Große GM, Neubert L, Falk CS, Jonigk D, Kühnel MP, Gabriel MM, Wilhelmi M, Weissenborn K, Schrimpf C. Die Rolle chemotaktischer Zytokine als mögliche Biomarker zur Identifikation vulnerabler Stenosen der Arteria carotis interna. Deutschen Gesellschaft für Neurologie (DGN) 2019, Stuttgart.

 

Stauß RD, Große GM, Neubert L, Falk CS, Jonigk D, Kühnel MP, Gabriel MM, Wilhelmi M, Weissenborn K, Schrimpf C. Die Rolle chemotaktischer Zytokine als mögliche Biomarker zur Identifikation vulnerabler Stenosen der Arteria carotis interna. Deutschen Gesellschaft für Gefäßchirurgie (DGG) 2019, Mannheim.

 

Jonigk D. Interstitial Lung Diseases, ILD Workshop 2019, Kathmandu University.

 

Jonigk D. Diagnose Worshop ILD 2019, Braunschweig.

 

Jonigk D. Comprehensive approaches to pulmonary pathology. Translational lung research center (TLRC) 2019, Heidelberg.

 

Jonigk D. Interstitielle Lungenerkrankungen aus Sicht des Pathologen. Roche Diagnose Workshop ILD 2019, Berlin.

 

Jonigk D. Molecular background of pulmonary patterns. Boehringer Ingelheim 2019, Biberach.

 

Beneke V, Grahl N, Danov O, Konzok S, Braubach P, Jonigk D, Warnecke G, Pfennig O, Fieguth HG, Braun A, Sewald K, Häußler S, Wronski S. Pseudomonas aeruginosa flagellin modulates the immune response in ex vivo lung tissue slices. ERS 2019, Madrid.

 

Khan P, Boesch M, Fang L, Knudsen L, Savic S, Jonigk D, Kühnel M, Tamm M, Brutsche M, Baty F, Hostettler KE. IPF lung resident mesenchymal stem cells differentiate into epithelial cells displaying a disease-specific transcriptome. ERS 2019, Madrid.

 

Jonigk D. Interstitielle Lungenerkrankungen. Forum Lungenfibrose 2019, Radebeul.

 

Jonigk D. (Molecular) Diagnostic at interstitial Lung Diseases. 18th Fraunhofer Seminar "Models of Lung Disease" 2019, Hannover.

 

Obernolte H, Ritter D, Knebel J, Niehof M, Braubach P, Jonigk D, Warnecke G, Zardo P, Fieguth HG, Pfennig O, Braun A, Sewald K. Induction of pathophysiological changes in the extracellular matrix but not inflammation as early events of cigarette smoking in fresh human lung tissue. DZL Annual Meeting 2019, Mannheim.

 

Höfer A, Jonigk D, Hartleben B, Geffers R, Klawonn F, Verboom M, Hallensleben M, Hübscher SG, Manns MP, Jaeckel E, Taubert R. Molecular classifier for T cell-mediated and antibody-mediated rejection after liver transplantation. EASL/ILC2019, Vienna.

 

Sewald K, Braun A, Braubach P, Jonigk D. Integrating Human Tissue into Research and Development: Fresh Lung Tissue for Basic and Applied Research. DZL Annual Meeting 2019, Mannheim.

 

Braubach P, Neubert L, Kühnel MP, Welte T, Gottlieb J, Warnecke G, Haverich A, Jonigk D. Hannover Lung Tissue Bank – Report 2018. DZL Annual Meeting 2019, Mannheim.

 

Neubert L, Borchert P, Shin H-O, Linz F, Wagner WL, Warnecke G, Laenger F, Haverich A, Stark H, Hoeper MM, Kuehnel MP, Ackermann M, Jonigk D. Comprehensive Three-dimensional Morphology of Neoangiogenesis in Pulmonary Veno-occlusive Disease and Pulmonary Capillary Hemangiomatosis. DZL Annual Meeting 2019, Mannheim.

 

Braubach P, Märzke I, Länger F, Kühnel MP, Jonigk D. Alveolar fibroelastosis – a proposition for a comprehensive histopathological definition. DZL Annual Meeting 2019, Mannheim.

 

Danov O, Greif A, Gael M, Bailly B, Braubach P, Jonigk D, Fieguth HG, Warnecke G, von Itzstein M, Sewald K, Wronski S, Braun A. Immune response to pandemic H1N1 Influenza virus infection in human precision-cut lung slices. 29th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 2019, Amsterdam.

 

Kamp J-C, Tudorache I, Jonigk D, Länger F, Haverich A, Welte T, Prasse A, Hoeper M, Warnecke G. ISHLT Konferenz 2019, Orlando, Florida/USA.

 

Schaadt N, Jonigk D. HiLF 2018, MHH Hanover.

 

Stanke F, Tamm S, Braubach P, Schreck F, Wyrwoll M, Jonigk D, Janciauskiene S. Analysis of alpha-1-antitrypsin as a modifying agent of CFTR Expression. DZL Annual Meeting 2018, Bad Nauheim.

 

Krupar R, Watermann C, Paternack H, Ribbat-Idel J, Kuehnel M, Jonigk D. Primary and Recurrent Head and Neck Squamous Carcinomas are Strkingly Different Regarding their Immun Microenviroment. 1st Symposium on Cancer-Immuno-Oncology 2018, Lübeck.

 

Jonigk D. Translation in Transplantation. Sechenov University 260th Anniversary Celebration Moskau/Russland 2018.

 

Jonigk D. Diagnosting interstitial lung disease. German-Mazedonian tutorial on updates in pathology 2018, Skopje.

 

Höfer A, Jonigk D, Hartleben B, Verboom M, Hallensleben M, Hübscher S, Manns M, Jaeckel E, Taubert R. Donor Specific Antibodies are Associated with more Inflammation, More Fibrosis and Higher Expression of Rejection Associated Transcripts in Subclinically Rejected Liver Allografts. TTS 2018, Madrid 2018.

 

Höfer A, Hartleben B, Jonigk D, Schlue J, Verboom M, Hallensleben M, Hübscher S, Manns M, Jaeckel E, Taubert R. Prospective Evaluation of Noninvasive Cell Death Marker and Donor Specific Antibodies as Predictors of Subclinical Graft Inflammation and Graft Fibrosis. Transplantation. TTS 2018, Madrid

 

Jonigk D. Histopathologische Aspekte interstitieller Lungenerkrankungen. DZL Expertenforum Lungenfibrose, Hannover 2018.

 

Jonigk D. Interstitielle Lungenerkrankungen aus Sicht der Pathologie.Roche Diagnoseworkshop interstitielle Lungenerkrankungen 2018, Berlin.

 

Borchert P, Mägel L, Stark H, Köper M, Hussein K, Kühnel M, Jonigk D. Pulmonary veno-occlusive disease: Reevaluation von 68 Fällen. DGP 2018.

 

Jonigk D. Interstitial lung diseases. DGP 2018.

 

Hesse C, Mang S, Wollin L, Niehof M, Braubach P, Jonigk D, Kühnel M, Warnecke G, Pfennig O, Fieguth H-G, Braun A, Sewald K. Unravelling specific mechanisms of wound healing and pulmonary fibrosis in human ex vivo lung tissue slices. ERS 2018.

 

Legchenko E, Chouvarine P, Borchert P, Fernandez-Gonzalez A, Snay E, Meier M, Maegel L, Mitsialis S.A, Rog-Zielinska E, Kourembanas S, Jonigk D, Hansmann G. The PPAR? Agonist Pioglitazone Reverses Pulmonary Arterial Hypertension (PAH) and Prevents Right Heart Failure through Fatty Acid Oxidation (FAO). 2018.

 

Twisterling E S, Dahlmann F, Dehmel S, Wronski S, Braubach P, Jonigk D, Warnecke G, Krüger M, Zardo P, Sewald K, Braun A. Comparison of IP-10 production induced by ex-vivo stimulation with Respiratory Syncytial Virus (RSV) and the TLR3 agonist Poly I:C in human and non-human primate lung tissues. EAACI Congress 2018.

 

Obernolte H, Braubach P, Jonigk D, Beinke S, Belyaev N N, Lennon M, Warnecke G, Fieguth H, Hessel E M, Braun A, Sewald K, Wronski S. Transcriptomic analyses reveal anti-viral responses of epithelial cells and multiple immune cell types in HRV infected human lung tissue. EAACI Congress 2018.

 

Hesse C, Mang S, Niehof M, Braubach P, Jonigk D, Warnecke G, Pfennig O, Fieguth HG, Braun A, Sewald K. Specific induction of pro-fibrotic biomarker in human ex vivo lung tissue slices. DZL annual meeting 2018.

 

Hesse C, Mang S, Wollin L, Hoymann HG, Niehof M, Braubach P, Jonigk D, Kühnel MP, Warnecke G, Pfennig O, Fieguth HG, Braun A, Sewald K. Pirfenidone attenuates pro-fibrotic biomarker in ex vivo lung tissue slices. ATS meeting 2018.

 

Albrecht M, Oluwaseun DI, Pallenberg S, Camargo-Neumann J, Witt M, Jonigk D, Braubauch P, Warnecke G, Hansen G, Dittrich AM. IL-17A producing lymphocytes in end stage lung disease. DZL Jahresmeeting 2018.

 

Diestelhorst J, Junge N, Jonigk D, Schlue J, Falk CS, Manns MP, Baumann U, Jaeckel E, Taubert R. Baseline IgG, AIH score and IL2 can predict subsequent biochemical remission in paediatric autoimmune hepatitis. 2017.

 

Wrede C, Knudsen L, Schneider JP, Faßbender S, Jonigk D, Mühlfeld C, Ochs M, Hegermann J. Volume Electron Microscopy of Human Lung Tissue. DZL 2017.

 

Teiken K, Kühnel M, Mägel L, Braubach P, Welte T, Gottlieb J, Warnecke G, Haverich A, Kreipe H, Jonigk D. Inflammation and fibrogenesis in early lesions of chronic lung allograft dysfunction. SFB International Symposium: Cellular and Molecular Mechanisms and New Therapeutic Concepts in Transplantation 2017.

 

Jonigk D (Invited Speaker). Morphological and molecular injury patterns of the transplanted lung. International Symposium: Cellular and Molecular Mechanisms and New Therapeutic Concepts in Transplantation. SFB International Symposium: Cellular and Molecular Mechanisms and New Therapeutic Concepts in Transplantation 2017.

 

Mikosz A, Strange C, Janciauskiene S, Stolk J, Braubach P, Jonigk D, Sandhaus R, Petrache I, Serban KA. Lectin complement pathway activation in COPD and alpha-1 antitrypsin (A1AT) deficiency. Abstract ATS 2018.

 

Jonigk D. Interstitial lung disease: The view of the pathologist. Roche Workshop: idiopathic pulmonary fibrosis. Berlin 2017.

 

Weissinger EM, Metzger J, Schleuning M, Schmid C, Messinger D, Beutel G, Wagner E, Schetelig J, Baurmann H, Rank A, Stölzl F, Schäfer-Eckhard K, Westphal K, Bethge W, Bunjes D, Heidenreich D, Klein S, Wolf D, Holler E, Kreipe H, Jonigk D, Türüchanow I, Rothmann C, Raad J, Durban A, Hamwi I, Erhlich S, Schweier P, Ihlenburg-Scharz D, Krauter J, Stadler M, Ganser A. Multicentre, double-blind, placebo-controlled clinical trial (Pre-GvHD) for prediction and pre-emptive treatment of acute GvHD. ASH 2017, Atlanta.

 

Lam J, Neehus A, Haake K, Merkert S, Mucci A, Ackermann M, Schubert M, Happle C, Kühnel MP, Goethe R, Jonigk D, Martin U, Baumann U, Schambach A, Roesler J, Lachmann N. Impaired IFNγ-Signaling and Mycobacterial Clearance in IFNγR1 Deficient Human iPSC-Derived Macrophages. European Students' Conference 2017.

 

Obernolte H, Ritter D, Knebel J, Braubach P, Jonigk D, Warnecke G, Zardo P, Fieguth H, Pfennig O, Braun A, Sewald K. Cigarette smoke induces biomarkers of COPD in fresh human lung tissue. 10th World Congress “Alternatives and Animal use in the Life Sciences” 2017.

 

Hesse C, Mang S, Hoymann HG, Niehof M, Braubach P, Jonigk D, Kühnel M, Warnecke G, Pfennig O, Fieguth HG, Braun A, Sewald K. Description of a pro-fibrotic biomarker pattern in ex vivo lung tissue slices with high clinical relevance. 10th World Congress “Alternatives and Animal Use In the Life Sciences” 2017.

 

Mitschke K, Mägel L, Müller Brechlin A, Engelhardt R, Izykowski N, Kühnel M, Kreipe H, Länger F, Hussein K, Jonigk D. NanoString nCounter™ gene expression analysis of tumour stem cell factors in EBV+ post-transplant smooth muscle tumours (PTSMT) and EBV angioleiomyomas show similar expression profiles. DGP 2017.

 

Obernolte H, Braubach P, Jonigk D, Beinke S, Belyaev NN, Lennon M, Fieguth H, Hessel EM, Braun A, Sewald K, Wronski S. Transcriptomic analyses reveal anti-viral responses of epithelial cells and multiple immune cell types in HRV infected human lung tissue. ERS 2017.

 

Braubach P, Rath B, Izykowski N, Länger F, Kühnel M, Jonigk D. Systematic evaluation of reference genes for non-neoplastic pulmonary diseases with RT-qPCR and nCounter technology. DGP 2017.

 

Jonigk D, Mägel L, Mitschke K, Braubach B, Golpon H, Welte T, Janciauskiene S, Gottlieb J, Eder M, Stadler M, Warnecke G, Haverich A, Kreipe H, Kühnel M, Länger F. Similar molecular subtypes of lung injury patterns in interstitial lung disease, stem cell and lung transplantation. 58. Kongress der Deutschen Gesellschaft für Pneumologie und Beatmungsmedizin e.V. 2017.

 

Hesse C, Mang S, Hoymann HG, Niehof M, Braubach P, Jonigk D, Kühnel M, Warnecke G, Pfennig O, Fieguth HG, Braun A, Sewald K. Description of a pro-fibrotic biomarker pattern in precision-cut lung slices (PCLS). JRS 2017.

 

Hesse C, Mang S, Hoymann HG, Niehof M, Braubach P, Jonigk D, Kühnel M, Warnecke G, Pfennig O, Fieguth HG, Braun A, Sewald K. Description of a pro-fibrotic biomarker pattern in precision-cut lung slices (PCLS). DZL Jahrestreffen 2017, Munich.

 

Höfer A, Verboom M, Hallensleben M, Hartleben B, Jonigk D, Schlue J, Lehner F, Hübscher S, Manns MP, Jaeckel E, Taubert R. Donor specific antibodies are associated with higher inflammatory activity, more fibrosis and higher expression of rejection associated transcripts in human liver allografts with subclinical rejection. International Liver Congress 2017, Amsterdam.

 

Höfer A, Verboom M, Hallensleben M, Hartleben B, Jonigk D, Schlue J, Lehner F, Hübscher S, Manns M, Jaeckel E, Taubert R. Donor specific antibodies are associated with higher inflammatory activity, more fibrosis and higher expression of rejection associated transcripts in subclinical rejected human liver allografts. Abstracts of the 26th Annual Meeting of the German Transplantation Society 2017.

 

Hesse C, Mang S, Hoymann HG, Niehof M, Braubach P, Jonigk D, Kühnel M, Warnecke G, Pfennig O, Fieguth HG, Braun A, Sewald K. Identification of pro-fibrotic biomarkers in precision-cut lung slices (PCLS). ATS 2017, Washington, DC.

 

Jonigk D, Rath B, Borchert P, Braubach P, Maegel L, Izykowski N, Warnecke G, Sommer W, Kreipe H, Blach R, Anklamm A, Haverich A, Eder M, Stadler M, Welte T, Gottlieb J, Kuehnel M, Laenger F. Alveolar fibroelastosis and bronchiolitis obliterans after lung and stem cell transplantation: comparative analysis of morphological and molecular motifs. ATS 2017, Washington, DC.

 

Maegel L, Kuehnel M, Ludewig B, Borchert P, Rafikova O, Janciausciene S, Warnecke G, Hoeper MM, Black SM, Jonigk D. Histomorphological and molecular characterization of human and Sugen 5416/hypoxia induced plexiform vasculopathy. ATS 2017, Washington, DC.

 

Jonigk D. Translational reasearch in lung diseases. DGP-Nachwuchsakademie 2016, Geisenheim (Rheingau).

 

Jonigk D. Lungenfibrose aus Sicht der Pathologie. 2. DZL Expertenforum Lungenfibrose 2016, Hanover.

 

Hesse C, Mang S, Hoymann HG, Niehof M, Braubach P, Jonigk D, Warnecke G, Pfennig O, Fieguth HG, Braun A, Sewald K. Identification of pro-fibrotic biomarkers in precision-cut lung slices (PCLS).EUSAAT 2016, Linz.

 

Besa V, Hager T, Länger F, Ennekes V, Jonigk D, Theegarten D. Classification of rejection in lung transplantation: Experience of second opinion evaluation. Deutsche Transplantationsgesellschaft 2016, Essen.

 

Jonigk D. Dissecting the pulmonary vasculature in PAH. Pulmonary Hypertension Symposium - Update 2016, Hanover.

 

Weissinger E, Metzger J, Schleuning M, Schmid C, Beutel G, Rank A, Wager E, Schetelig J, Stöltzl F, Schäfer-Eckhard K, Bethge W, Bunjes D, Heindenreich D, Holler E, Niederwieser D, Kreipe H, Westphal K, Wolff D, Rothmann C, Schweier P, Tueruechanow I, Ihlenburg-Schwarz D, Durban A, Raad J, Dakna M, Jonigk D, Hamwi I, Hambach L, Krauter J, Stadler M, Ganser A. First Analysis of the multicentre, blinded, Placebo-controlled PRE-GvHD crinical-trial for prediction and pre-emptive treatment of acute GvHD in 210 of 260 patients. EHA 2016, Copenhagen.

 

Hesse C, Mang S, Hoymann HG, Niehof M, Braubach P, Jonigk D, Warnecke G, Pfennig O, Hieguth HG, Braun A, Sewald K. Induction of pro-fibrotic biomarkers in precision-cut lung slices (PCLS). ERS 2016, London.

 

Obernolte H, Braubach P, Jonigk D, Fieguth HG, Braun A, Wronski S, Sewald K. Rhinovirus infection in human lung slices is reduced by Rupintrivir. ERS 2016, London.

 

Wichmann J, Jiménez-Delgado S, Curths C, Schmitt A, Dunker S, Jonigk D, Braubach P, Kaup F-J, Braun A, Dahlmann F, Eggel A, Sewald K, Knauf S. Non-human primate and human precision-cut lung slices: a model to study efficacy of a novel disruptive IgE inhibitor. WIRM 2016, Davos.

 

Wichmann J, Jiménez-Delgado S, Curths C, Schmitt A, Dunker S, Jonigk D, Braubach P, Kaup F-J, Braun A, Eggel A, Sewald K , Dahlmann F, Knauf S. Efficacy assessment of a novel disruptive IgE inhibitor in non-human primate and human precision-cut lung slices. ATS 2016, San Francisco.

 

Weissinger EM, Metzger J, Schleuning M, Schmid C, Rank A, Beutel G, Wagner E, Schetelig J, Stölzl F, Schäfer-Eckhard K, Westphal K, Bethge W, Bunjes D, Wolf D, Holler E, Niederwieser D, Kreipe H, Jonigk D, Hamwi I, Hambach L, Schweier P, Türüchanow I, Rothmann C, Ihlenburg-Scharz D, Papkalla A, Raad J, Durban A, Dakna M, Krauter J, Stadler M, Ganser A. Urine proteomics (aGvHD_MS17) predicts acute GvHD and non-relapse mortality (interim-analyses of Pre-GvHD-trial. 42nd Annual Meeting of the European Society for Blood and Marrow Transplantation 2016, Valencia (Spain).

 

Jonigk D, Rath B, Maegel L, Golpon H, Izykowski N, Welte T, Janciauskiene S, Gottlieb J, Warnecke G, Haverich A, Kreipe H, Kuehnel M, Laenger F. Remodelling-related molecular profiles in different subforms of chronic lung allograft dysfunction. DZL Annual Meeting 2016, Hanover.

 

Wichmann J, Jiménez-Delgado S, Curths C, Schmitt A, Dunker S, Jonigk D, Braubach P, Kaup F-J, Braun A, Dahlmann F, Eggel A, Sewald K, Knauf S. A novel disruptive IgE inhibitor: Efficacy assessment in non-human primate and human precision-cut lung slices. DZL Annual Meeting 2016, Hanover.

 

Konzok S, Jonigk D, Peter D, Braubach P, Pfennig O, Fieguth H-G, Braun A, Sewald K. Bacterial and viral PAMPs and cellular DAMPs lead to activation of the inflammasome in human lung tissue ex-vivo. DZL Annual Meeting 2016, Hanover.

 

Braubach P, Lippmann T, Kuehnel M, Häußler S, Maus U, Ding N, Lehmann U, Länger F, Kreipe H, Jonigk D. In situ molecular diagnostics of infectious diseases. DZL Annual Meeting 2016, Hanover.

 

Obernolte H, Braubach P, Jonigk D, Fieguth H-G, Müller M, Braun A, Sewald K, Wronski S. Rhinovirus infection in human Precision-Cut Lung Slices is reduced by therapeutic intervention. DZL Annual Meeting 2016, Hanover.

 

Braubach P , Schaadt N, Lippmann T, Kuehnel M, Jonigk D. Characterization of Pseudomonas aeruginosa biofilm morphology and host inflammation in explanted cystic fibrosis lungs. DZL Annual Meeting 2016, Hanover.

 

Braubach P, Lippmann T, Kuehnel M, Anagnostopoulos I, Kreipe HH, Jonigk D. Fluorescence in-situ hybridization as an aid in the diagnosis of Whipple’s disease. DGP 2016, Berlin.

 

Maegel L, Ludewig B, Borchert P, Rafikova O, Kellner M, Kuehnel M, Jonigk D. Histomorphological and molecular characterization of human plexiform vasculopathy and its Sugen (SU 5416)/hypoxia induced rat model. DGP 2016, Berlin.

 

Jonigk D, Rath B, Maegel L, Golpon H, Izykowski N, Welte T, Janciauskiene S, Gottlieb J, Warnecke G, Haverich A, Kreipe H, Kuehnel M, Laenger F. Remodelling-related molecular profiles in different subforms of chronic lung allograft dysfunction. ATS 2016, San Francisco.

 

Kuehnel M, Wehling J, Kellner M, Warnecke G, Heidrich M, Izykowski N, Grothausmann R, Knudsen L, Welte T, Haverich A, Laenger F, Kreipe H, Jonigk D. 3D MORPHOLOGY MEETS MOLECULAR PATHOLOGY: Chronic Lung Alveolar Dysfunction revisited. ATS 2016, San Francisco.

 

Laenger F, Izykowski N, Rische J, Braubach P, Gottlieb J, Welte T, Haverich A, Warnecke G, Kreipe H, Kuehnel M, Jonigk D. Prospective Molecular Profiling in Human Lung Allografts. ATS 2016, San Francisco.

 

Konzok S, Jonigk D, Peter D, Braubach P, Braun A, Sewald K. Different pathways of inflammasome activation in human Precision-Cut Lung Slices (PCLS). ATS 2016, San Francisco.

 

Wichmann J, Jiménez-Delgado S, Curths C, Schmitt A, Dunker S, Jonigk D, Braubach P, Kaup F-J, Braun A, Eggel A, Sewald K, Dahlmann F, Knauf S. Efficacy assessment of a novel disruptive IgE inhibitor in non-human primate and human precision-cut lung slices. ATS 2016, San Francisco.

 

Obernolte H, Ritter D, Knebel J, Braubach P, Jonigk D, Fieguth H-G, Braun A, Sewald K. Cigarette smoke and cigarette smoke condensate induce early biomarkers of inflammation and cytotoxicity in Precision-Cut Lung slices. ATS 2016, San Francisco.

 

Jonigk D. Companion diagnostics in Breastcancer covering all methods including IHC, CISH and FISH. Najaarscongres WIHC 2015, Netherlands.

 

Maegel L, Borchert P, Lippmann T, Hoeper M, Warnecke G, Schermuly R, Kreipe H, Kühnel M, Jonigk D. Three dimensional (3D) analysis of human plexiform vasculopathy in pulmonary hypertension. „MHH – 50 Jahre wissenschaftliche Exzellenz in der Medizin“ – Wissenschaftliches Symposium 2015.

 

Kühnel M, Kellner M, Wehling J, Warnecke G, Heidrich M, Izykowski N, Vogel-Claussen J, Lorbeer R, Antonopoulos G, Janciauskiene S, Grothausmann R, Knudsen L, Ripken T, Meyer H, Kreipe H, Ochs M, Jonigk D. Correlating 3D morphology with molecular pathology: fibrotic remodelling in human lung biopsies and animal models. „MHH – 50 Jahre wissenschaftliche Exzellenz in der Medizin“– Wissenschaftliches Symposium 2015.

 

Lippmann T, Braubach P, Müsken M, Häußler S, Kühnel M, Lehmann U, Länger F, Kreipe H, Jonigk D. In-situ Molecular Diagnostics of infectious diseases. „MHH – 50 Jahre wissenschaftliche Exzellenz in der Medizin“ – Wissenschaftliches Symposium 2015.

 

Mund E, Braubach P, Länger F, Lippmann T, Warnecke G, Haverich A, Vogel-Claussen J, Ruppert C, Seeger W, Welte T, Jonigk D. Workup and Biobanking of Fresh Human Lung Explants. „MHH – 50 Jahre wissenschaftliche Exzellenz in der Medizin“ – Wissenschaftliches Symposium 2015.

 

Maegel L, Lippmann T, Höper M, Warnecke G, Schermuly R, Kreipe H, Kühnel M, Jonigk D. Plexiforme Vaskulopathie bei pulmonaler Hypertonie. 99. Jahrestagung der DGP 2015, Frankfurt.

 

Lippmann T, Müsken M, Häußler S, Kühnel M, Lehmann U, Laenger F, Kreipe H, Jonigk D, Braubach P. In-situ Erreger Diagnostik. 99. Jahrestagung der DGP 2015, Frankfurt.

 

Braubach P, Lippmann T, Engelhardt R, Maus U, Ding N, Müsken M, Häußler S, Laenger F, Jonigk D. In situ diagnostic of bacterial infections. DZL Summer School 2015.

 

Mitschke K, Maegel L, Engelhardt R, Izykowski N, Kreipe H, Laenger F, Hussein K, Jonigk D. Molecularpathological Analysis of Angiogenesis in Angioleiomyomas. 99. Jahrestagung der DGP 2015, Frankfurt.

 

Weiss A, Gernert K, Schäfer S, Maegel L, Jonigk D, Ghofrani HA, Weissmann N, Grimminger F, Seeger W, Schermuly RT. MicroRNA-9 is a regulator of PDGFRβ expression in pulmonary arterial hypertension. TLRC Lung Conference-4th DZL International Symposium 2015.

 

Lippmann T, Braubach P, Laenger F, Mund E, Warnecke G, Haverich A, Vogel-Claussen J, Ruppert C, Ochs M, Seeger W, Welte T, Jonigk D. Workup and biobanking of fresh human lung explants. DZL-Jahrestreffen 2015, Hamburg.

 

Izykowski N, Kuehnel MP, Mund E, Ochs M, Gottlieb J, Warnecke G, Kreipe HH, Laenger F, Jonigk D. Three-dimensional (3D) reconstruction of human bronchiolitis obliterans lesions. DZL-Jahrestreffen 2015, Hamburg.

 

Lippmann T, Maegel L, Mund E, Hoeper MM, Ochs M, Warnecke G, Schermuly R, Jonigk D, Kuehnel MP. Three dimensional (3D) analysis of human plexiform vasculopathy in pulmonary hypertension. DZL-Jahrestreffen 2015, Hamburg.

 

Knöfel AK, Siemeni T, Frank N, Madrahimov N, Salman J, Sommer W, Jansson K, Jonigk D, Avsar M, Haverich A, Warnecke G. Lung transplant recipients with elevated peripheral blood counts of CD127 low, FoxP3+ and CTLA4+CD4+CD25 high T cells develop less severe donor specific transplant arteriosclerosis in humanized mice. DGTHG 2015, Freiburg.

 

Knöfel AK, Siemeni T, Frank N, Madrahimov N, Jonigk D, Salman J, Sommer W, Jansson K, Avsar M, Haverich A, Warnecke G. Elevated peripheral blood counts of CD127low, FoxP3+ CD4+CD25 high T cells in lung transplant recipients leads to less severe donor specifi transplant arteriosclerosis in humanized mice. ISHLT 2015, Nice.

 

Jonigk D. Luftwegsabstoßung und chronisches Transplantatversagen. Konsensustreffen Pathologie der Lungentransplantation 2014, Hanover.

 

Jonigk D. Myofibroblastäre genexpression bei fibrosierenden Lungengerüsterkrankungen.
20. Symposium zur Hochschulinternen Leistungsförderung (HiLF) 2014, Hanover.

 

Jonigk D. Interstitielle Lungenerkrankungen. Kasuistisches Forum Niedersächsischer Pathologen 2014, Hanover.

 

Jonigk D. Molekularpathologie des Mammakarzinoms. Internationale Akademie für Pathologie 2014, Bonn.

 

Wehling J, Kellner M, Izykowski N, Braubach P, Knudsen L, Haverich A, Warnecke G, Vogel-Claussen J, Ochs M, Laenger F, Kühnel M, Jonigk D. Integrative molekulare und anatomische Charakterisierung der idiopathischen Lungenfibrose. 98. Jahrestagung der Deutschen Gesellschaft für Pathologie 2014, Berlin.

 

Jonigk D. Aberrierender reparativer Gewebeumbau. 98. Jahrestagung der Deutschen Gesellschaft für Pathologie 2014, Berlin.

 

Izykowski N, Braubach P, Rische J, Rath B, Maegel L, Gottlieb J, Welte T, Haverich A, Kreipe H, Laenger F, Jonigk D. Molecular profiling in human pulmonary allografts. 98. Jahrestagung der Deutschen Gesellschaft für Pathologie 2014, Berlin.

 

Wehling J, Kellner M, Izykowski N, Braubach P, Knudsen L, Haverich A, Warnecke G, Vogel-Claussen J, Ochs M, Laenger F, Kühnel M, Jonigk D. Integrative molecular and anatomical characterization of idiopathic pulmonary fibrosis. Breath Lecture Series „Pneumology for lung researchers“ 2014, Hanover.

 

Danov O, Jimènez Delgado SM, Drake H, Seehase S, Hohlbaum AM, Bersch C, Jonigk D, Warnecke G, Braun A, Sewald K. IL-13 induced asthma model in human precision-cut lung slices. 9th World Congress on Alternatives and Animal Use in Life Sciences 2014, Prag.

 

McCormick Smith I., Sedlacek L, Jonigk D, Rickerts V. Identification of Scedosporium and other fungi in formalin fixed, paraffin embedded tissue from patients with cystic fibrosis by broadrange PCR and Fluorescence in situ hybridization (FISH). Uetrecht 2014.

 

Wiegmann B, Jonigk D, Maegel L, Braubach P, Höffler K, Bachmann S, Janke J, Haverich A. Miniaturization of the Organ Care System® into rat lungs for the establishment of ex-vivo therapy. Jahrestagung der DGTHG 2014.

 

Jansson K, Sommer W, Avsar M, Salman J, Knöfel A-K, Hewicker-Trautwein M, Jonigk D, Haverich A, Warnecke G. Pretreatment with donor alloantigen and anti-CD4-antibody 28 days befor lung transplantation leads to immunization rather than tolerance in miniature pigs. Jahrestagung der DGTHG 2014.

 

Wehling J, Braubach P, Kellner M, Izykowski N, Knudsen L, Meyer H, Haverich A, Warnecke G, Vogel-Claussen J, Ochs M, Kreipe H, Laenger F, Kuehnel M, Jonigk D. Integrative molecular and anatomical characterization of idiopathic pulmonary fibrosis. DZL-Jahrestreffen 2014, Heidelberg.

 

Izykowski N, Braubach P, Rische J, Rath B, Maegel L, Gottlieb J, Welte T, Haverich A, Kreipe H, Laenger F, Jonigk D. Prospective molecular profiling in human pulmonary allografts. DZL-Jahrestreffen 2014, Heidelberg.

 

Jansson K, Sommer W, Avsar M, Salman J, Knöfel A-K, Falk C, Hewicker-Trautwein M, Jonigk D, Haverich A, Warnecke G. Pretreatment with donor alloantigen and anti-CD4-antibody 28 days before lung transplantation leads to immunization rather than tolerance in miniature pigs. ISHLT 2014.

 

Fytili P, Krech T, Zell S, Bockmeyer CL, Jonigk D, Lehner F, Kreipe H, Manns MP, Becker JU, Wedemeyer H. miRNA based score for the correct diagnosis of rejection vs recurrent hepatitis C in liver transplanted patients. ILC 2014, London.

 

Ludewig B, Mägel L, Izykowski N, Rath B, Black S, Ratikova O, Haverich A, Golpon H, Warnecke G, Höper M, Kreipe H, Länger F, Jonigk D. Mechanisms of pulmonary arterial hypertension in humans and rats. DZL-Breath Retreat 2013.

 

Rath B, Ludewig B, Izykowski N, Braubach P, Golpon H, Welte T, Haverich A, Warnecke G, Gottlieb J, Kreipe H, Länger F, Jonigk D. Bronchiolitis obliterans after stem cell and lung transplantation. DZL-Breath Retreat 2013.

 

Izykowski N, Mägel L, Schormann E, Hussein K, Länger F, Kreipe H, Jonigk D. Expression profile of microRNA and angiogenesis-associated factors in Epstein-Barr virus-associated post-transplant smooth muscle tumours. DZL-Breath Retreat 2013.

 

Ludewig B, Izykowski N, Rath B, Black S.M, Rafikova O, Haverich A, Golpon H, Warnecke G, Hoeper M, Kreipe H, Länger F, Jonigk D. Experimental models of pulmonary arterial hypertension in humans. 97. Jahrestagung der Deutschen Gesellschaft für Pathologie 2013, Heidelberg.

 

Izykowski N, Jonigk D, Maegel L, Schormann E, Länger F, Kreipe H, Hussein K. MicroRNA expression profile in Epstein-Barr virus-associated posttransplanted smooth muscle tumours. 97. Jahrestagung der Deutschen Gesellschaft für Pathologie 2013, Heidelberg.

 

Rath B, Ludewig B, Izykowski N, Haverich A, Warnecke G, Gottlieb J, Kreipe H, Jonigk D, Länger F. Molecular characterization of bronchiolitis obliterans after stem cell transplantation as a manifestation of GvHD. 97. Jahrestagung der Deutschen Gesellschaft für Pathologie 2013, Heidelberg.

 

Jonigk D, Rische J, Izykowski N, Maegel L, Gottlieb J, Welte T, Haverich A, Kreipe H, Laenger F. Molecular profiling in human pulmonary allografts. 97. Jahrestagung der Deutschen Gesellschaft für Pathologie 2013, Heidelberg.

 

Länger F, Golpon H, Dickgreber N, Haverich A, Krüger M, Schormann E, Rath B, Jonigk D, Kreipe H, Lehmann U. Comparative analysis of detection methods of EML4-ALK translocation in NSCLC. 97. Jahrestagung der Deutschen Gesellschaft für Pathologie 2013, Heidelberg.

 

Krech T, Fytili P, Zell S, Bockmeyer C, Jonigk D, Wedemeyer HH, Kreipe H, Becker JU. Differentially expressed microRNAs as a prognostic marker of liver allograft survival in Hepatitis C patients. 97. Jahrestagung der Deutschen Gesellschaft für Pathologie 2013, Heidelberg.

 

Atanasova S, Evers A, Jonigk D, Wilker S, Fuchs-Moll G, Petri K, Zakrzewicz A, Fischer A, Obert M, Schmitz J, Hirschburger M, Padberg W, Grau V. Experimental chronic lung allograft damage. 15th International Congress of Immunology (ICI).

 

Zimpfer A, Wolff K, Jonigk D, Hildebrandt G, Zhivov A, Erbersdobler A, Guthoff RF. Aderhautmelanome nach fraktionierter CyberKnife Radiotherapie: eine prospektive klinisch-pathologische Studie. Deutschen Ophthalmologenkongress 2013.

 

Pilatz A, Altinkilic B, Schormann E, Maegel L, Izykowski N, Becker J, Weidner W, Kreipe H, Jonigk D. Molecular Profiling in Juvenile Phimosis. 64. Kongress der Deutschen Gesellschaft für Urologie 2012, Leipzig.

 

Boeer U, Luetzner S, Jonigk D, Klingenberg M, Haverich A, Wilhelmi M. Effect of CCN1 coating of decellularized equine carotid arteries on local biocompatibility and humoral immunogenicity in a heterogenous animal model. Biomed Tech 2012, Berlin.

 

Boeer U, Luetzner S, Jonigk D, Klingenberg M, Haverich A, Wilhelmi M. Effect of CCN1 coating of decellularized equine carotid arteries on local biocompatibility and humoral immunogenicity in a heterogenous animal model. 46th annual conference of the German Society for Biomedical Engineering 2012, Jena.

 

Jonigk D, Rische J, Maegel L, Golpon H, Izykowski N, Bockmeyer CL, Welte T, Janciauskiene S, Gottlieb J, Warnecke G, Haverich A, Kreipe H, Laenger F. Remodelling-related molecular profiles in interstitial pulmonary fibrosis. UGMLC / DZL Symposium 2012, Marburg.

 

Jonigk D, Rische J, Maegel L, Golpon H, Izykowski N, Bockmeyer CL, Welte T, Janciauskiene S, Gottlieb J, Warnecke G, Haverich A, Kreipe H, Laenger F. DGP Remodelling-related molecular profiles in interstitial pulmonary fibrosis. 96. Jahrestagung der Deutschen Gesellschaft für Pathologie 2012, Berlin.

 

Maegel L, Rische J, Tiede C, Salem J, Laenger F, Kreipe H, Hussein K, Jonigk D. Histomorphological and clinical characterization of Epstein-Barr-Virus-associated post-transplant smooth muscle tumours. 96. Jahrestagung der Deutschen Gesellschaft für Pathologie 2012, Berlin.

 

Jonigk D, Rische J, Maegel L, Golpon H, Izykowski N, Bockmeyer CL, Welte T, Janciauskiene S, Gottlieb J, Warnecke G, Haverich A, Kreipe H, Laenger F. Remodelling-related molecular profiles in interstitial pulmonary fibrosis. ATS International Conference 2012, San Francisco.

 

Rafikova O, Rafikova R, Aggarwal S, Jonigk D, Black SM. Ligand-independent EGFR activation in the development of pulmonary hypertension. ATS International Conference 2012, San Francisco.

 

Ueberberg B, Janze AK, Steinwede R, Maus R, Maegel L, Hoyman HG, Braun A, Laenger F, Jonigk D, Kolb M, Gauldie J, Welte T, Maus UA. Bacterial infection triggers exacerbation of established pulmonary fibrosis in mice: impact on lung protective immunity. ATS International Conference 2012, San Francisco.

 

Buechler G, Knoefel AK, Madrahimov N, Dreckmann K, Avsar M, Sommer M, Ziehme P, Jonigk D, Laenger F, Gottlieb J, Haverich A, Strueber M, Warnecke G. The induction of stable peripheral tolerance is a result of alloantigen priming and independent from pretransplant T cells in a porcine lung transplantation model. TTS 2012, Berlin.

 

Jonigk D, Rische J, Maegel L, Bockmeyer CL, Gottlieb J, Golpon H, Hoeper MM, Welte T, Haverich A, Lehmann U, Bock O, Kreipe H, Laenger F. Longitudinal molecular profiling in human pulmonary allografts. 95. Jahrestagung der Deutschen Gesellschaft für Pathologie 2011, Leipzig.

 

Bockmeyer CL, Maegel L, Rische J, Lehmann U, Nickel N, Hoeper MM, Golpon H, Kreipe H, Laenger F, Jonigk D. Expression der miRNA 143/145 und glattmuskulärer Marker in vaskulären Strukturen bei Patienten mit pulmonaler Hypertonie. 95. Jahrestagung der Deutschen Gesellschaft für Pathologie 2011, Leipzig.

 

Laenger F, Golpon H, Dickgreber N, Jonigk D, Kreipe H, Lehmann U. Heterogenität prognostischer und prädiktiver Marker im NSCLC in In-Situ-Läsionen, invasiven Karzinomen und Metastasen. 95. Jahrestagung der Deutschen Gesellschaft für Pathologie 2011, Leipzig.

 

Jonigk D, Rische J, Maegel L, Bockmeyer CL, Gottlieb J, Golpon H, Hoeper M, Welte T, Haverich A, Lehmann U, Bock O, Kreipe H, Laenger F. Longitudinal Profiling in Human Allografts. ATS International Conference 2011, Denver (USA).

 

Bockmeyer CL, Maegel L, Rische J, Lehmann U, Nickel N, Hoeper MM, Golpon H, Kreipe H, Laenger F, Jonigk, D. Expression of miR 143 / 145 and smooth muscle differentiation markers in vascular compartments of pulmonary hypertension. ATS International Conference 2011, Denver (USA).

 

Jonigk D, Bockmeyer CL, Maegel L, Nickel N, Gottlieb J, Welte T, Hoeper MM, Laenger F, Golpon H. Comparison of plexiform lesions in PAH and glomeruloid vascular structures in glioblastoma multiforme. ATS International Conference 2011, Denver (USA).

 

Nickel N, Jonigk D, Maegel L, Welte T, Hoeper MM, Laenger F, Golpon H. GDF-15 is abundantly expressed in plexiform lesions in patients with pulmonary arterial hypertension and affects proliferation and apoptosis of endothelial cells in vitro. ATS International Conference 2011, Denver (USA).

 

Knoefel AK, Madrahimov N, Dreckmann K, Avsar M, Sommer W, Jonigk D, Haverich A, Strueber M, Warnecke G. Rejection of bronchus transplants in third-party porcinized mice is regulated by allogenic CD4+ CD 25+ T cells. ISHL 31st Annual Meeting and Scientific Sessions 2011, San Diego (USA).

 

Jonigk D, Bockmeyer CL, Maegel L, Nickel N, Golpon H, Kreipe H, Laenger F. Angiogenic microenvironment / vascular remodelling in hypertensive pulmonary disease. ATS International Conference 2010, New Orleans (USA).

 

Jonigk D, Theophile K, Hussein K, Merk M, Maegel L, Lehmann U, Kreipe H, Laenger F. Aberrant Expression of TGF-β Superfamily Members in Fibrotic Airway Remodelling. ATS International Conference 2010, New Orleans (USA).

 

Laenger F, Jonigk D, Dickgreber N, Fischer S, Kreipe H, Lehmann. EGFR-Mutations in non-small cell lung cancer – prevalence, correlation with other biomarkers and intratumoral heterogeneity. 94. Jahrestagung der Deutschen Gesellschaft für Pathologie 2010, Berlin.

 

Bockmeyer CL, Jonigk D, Maegel L, Nickel N, Golpon H, Lehmann U, Kreipe H, Laenger F. MicroRNAs regulating neo-angiogenesis and vascular smooth muscle cell proliferation are differentially expressed in plexiform lesions of pulmonary arterial hypertension. 94. Jahrestagung der Deutschen Gesellschaft für Pathologie 2010, Berlin.

 

Jonigk D, Bockmeyer CL, Maegel L, Nickel N, Golpon H, Kreipe H, Laenger F. Angiogenic (micro)environment and vascular remodeling in high grade hypertensive pulmonary disease. 94. Jahrestagung der Deutschen Gesellschaft für Pathologie 2010, Berlin.

 

Schwerk N, Metzelder M, Weidemann J, Jonigk D, Hansen G, Dingemann J, Nustede R. Seltene Ursache eines persistierenden Stridors bei einem Kleinkind. 31. Jahrestagung der Gesellschaft für Pädiatrische Pneumologie 2009, Düsseldorf.

 

Jonigk D, Mark M, Theophile K, Laenger F, Hussein K, Bock O, Lehmann U, Kreipe H. Functional Compartments in diffuse fibrotic lung disease. 93. Jahrestagung der Deutschen Gesellschaft für Pathologie 2009, Freiburg.

 

Jonigk D, Theophile K, Hussein K, Lehmann U, Laenger F, Kreipe H. Recruitment and activation of (myo)fibroblasts in lung allografts undergoing chronic injury. 92. Jahrestagung der Deutschen Gesellschaft für Pathologie 2008, Berlin.

 

Jonigk D, Stuht S, Gwinner W, Franz I, Schwarz A, Kreipe H, Kerjaschki D, Hall H, Mengel M. Lymphatic Neoangiogenesis in Human Renal Allografts. 91. Jahrestagung der Deutschen Gesellschaft für Pathologie 2007, Magdeburg.

 

Jonigk D, Lehmann U, Stuht S, Wilhelmi M, Haverich A, Kreipe H, Mengel M. VEGF-alpha promotes recipient derived neoangiogenesis in inflammatory lesions in cardiac allograf. 91. Jahrestagung der Deutschen Gesellschaft für Pathologie 2007, Magdeburg.

 

Jonigk D, Lehmann U, Broecker V, Kreipe H, Mengel, M. Chimeric neoangiogenesis in recipient derived quilty lesions of the heart – Poster of Distinction. World Transplant Congress 2006, Boston.

 

Jonigk D, Mengel M, Lehmann U, Kreipe H. Quilty Lesions in Cardiac Allografts. 90. Jahrestagung der Deutschen Gesellschaft für Pathologie 2006, Berlin.

 

- 2019 -

 

Bogaard HJ, Legchenko E, Ackermann M, Kühnel MP, Jonigk DD, Chaudhary KR, Sun X, Stewart DJ, Hansmann G. The Adult Sprague-Dawley Sugen-Hypoxia Rat Is Still "the One:" A Model of Group 1 Pulmonary Hypertension: Reply to Le Cras and Abman. Am J Respir Crit Care Med. 2019 Nov 26. doi: 10.1164/rccm.201910-1983LE. (Impact Factor: 16.494)

 

Melchert J, Henningfeld KA, Richts S, Lingner T, Jonigk D, Pieler T. The secreted BMP antagonist ERFE is required for the development of a functional circulatory system in Xenopus. Dev Biol. 2019 Dec 14. pii: S0012-1606(19)30366-5. doi: 10.1016/j.ydbio.2019.12.007. (Impact Factor 2018: 3.262)

 

Ackermann M, Stark H, Neubert L, Schubert S, Borchert P, Linz F, Wagner W, Stiller W, Wielpütz M, Hoefer A, Haverich A, Mentzer S, Shah H, Welte T, Kuehnel M, Jonigk D. Morphomolecular motifs of pulmonary neoangiogenesis in interstitial lung diseases. ERJ 2019 (Impact Factor 2018: 12,242 / 5-year Impact Factor: 11,03)

 

Höfer A, Jonigk D, Hartleben B, Verboom M, Hallensleben M, Hübscher SG, Manns MP, *Jaeckel E, *Taubert R. : DSA are associated with more graft injury, more fibrosis and upregulation of rejection associated transcripts in subclinical rejection. Transplantation 2019 doi: 10.1097/TP.0000000000003034. (Impact Factor 2018/19: 4.593 / 5-year Impact Factor: n.a.)

Ercetin E, Richtmann S, Martinez-Delgado B, Gomez-Mariano G, Wrenger S, Korenbaum E, Liu B, DeLuca D, Kühnel MP, Jonigk D, Yuskaeva K, Warth A, Muley T, Winter H, Meister M, Welte T, Janciauskiene S, Schneider M. Clinical significance of SERPINA1 gene and its encoded alpha1-antitrypsin protein in NSCLC. Cancers 2019; 11(9). pii: E1306. doi: 10.3390/cancers11091306 (Impact Factor 2018: 6.162 / 5-year Impact Factor: n.a.)

Jonigk D, Stark H, Braubach P, Neubert Lavinia, Shin HO, Izykowski N, Welte Tobias, Janciauskiene S, Warnecke G, Haverich A, Kuehnel M, Laenger F. Morphological and molecular motifs of fibrosing pulmonary injury patterns. J Pathol Clin Res. 2019 doi: 10.1002/cjp2.141. (Impact Factor 2015: 7.381 / 5-year Impact Factor: n.a)

Madrahimov N, Haverich, A, Natanov R, Khalikov, A, Jonigk D, Knöfel A, Siemeni M, Norbert T. Warming and cooling device using thermoelectric Peltier elements tested on male mice. Laboratory Animals 2019 (Impact Factor 2018: 1.117 / 5-year impact Factor: n.a )

Kordes A, Preusse M, Willger S, Braubach P, Jonigk D, Haverich A, Warnecke G, Häussler S. Genetically diverse Pseudomonas aeruginosa populations display similar transciptomic profiles in a cystic fibrosis explanted lung. Nat Commun. 2019 10(1): 3397. doi: 10.1038/a41467-019-11414-3. (Impact Factor 2018: 11.88 / 5-year impact Factor: 5.435)

Schmidt H, Braubach P, Schilpp C, Lochbaum R, Neuland K, Thompson K, Jonigk D, Frick M, Dietl P, Wittekindt O. IL-13 impairs tight junctions in airway epithelia. Int J Mol Sci. 2019; 20(13). pii: E3222. doi: 10.3390/ijms20133222 (Impact Factor 2018: 4.183 / 5-year impact Factor 4.331)

Bickes MS, Pirr S, Heinemann AS, Fehlhaber B, Halle S, Völlgrt L,Willers M, Richter M, Böhne C, Albrecht M, Langer M, Pfeifer S, Jonigk D, Vieten G, Ure B, von Kaisenberg  C, Förster R, von Köckritz-Blickwede M, Hansen G, Viemann D. Constitutive TNF-α signaling in neonates is essential for the development of tissue-resident leukocyte profiles at barrier sites. FASEB J. 2019: fj201900796R. doi: 10.1096/fj.201900796R. (Impact Factor 2016: 5.498/ 5-year impact Factor: 5.435)

Funken D, Schmidtmayer U, Durisin M, Jonigk D, Baumann U, Dittrich AM. Listen carefully - an unusual cause of neonatal stridor. American Journal of Respiratory and Critical Care Medicine 2019 (AJRCCM). doi: 10.1164/rccm.201811-2213IM. (Impact Factor 2018: 15.24 / 5-year impact Factor: 14.53)

Tort Tarres M, Aschenbrenner F, Maus R, Stolper J, Schuette L, Knudsen L, Lopez-Rodriguez E, Jonigk D, Kuehnel M, DeLuca D, Prasse A, Welte T, Gauldie J, Kolbm M, Maus U. The Fms-like tyrosine kinase-3 ligand/lung dendritic cell axis contributes to regulation of pulmonary fibrosis. Thorax 2019. pii: thoraxjnl-2018-212603. doi: 10.1136/thoraxjnl-2018-212603. (Impact Factor 2017: 9.655 / 5-year impact Factor 7.719)

Eggers H, Krüger M, Stange K, Jonigk D, Biancosiono C, Rodt T, Fühner T, Murray T, Grünwald V, Ivanyi P. Sarcoid-like lesions mimicking pulmonary metastasis. Oncol Res Treat. 2019 28: 1-5. doi: 10.1159/000500206 (Impact Factor 2018: 1.292 / 5-year impact Factor­ 1.687)

Weiss A, Neubauer MC, Yerabolu D, Kojonazarov B, Schlueter BC, Neubert L, Jonigk D, Baal N, Ruppert C, Dorfmuller P, Pullamsetti S, Weissmann N, Ghofrani HA, Grimminger F, Seeger W, Schermuly RT. Targeting cyclin-dependent kinases for the treatment of pulmonary arterial hypertension. Nat Commun 2019; 10(1): 2204. doi: 10.1038/s41467-019-10135-x. (Impact Factor 2017: 12.353 / 5-year impact Factor: 13.691)

 

Sarikouch S, Theodoridis K, Hilfiker A, Boethig D, Laufer G, Andreas M, Cebotari S, Tudorache I, Bobylev D, Neubert L, Teiken K, Robertus JL, Jonigk D, Beerbaum P, Haverich A, Horke A. Early insight into In-vivo recelluarization of cell-free allogenic heart valves. Ann Thorac Surg. pii: S0003-4975(19)30414-X. doi: 10.1016/j.athoracsur.2019.02.058. (Impact Factor 3.770 / 5-year Impact: 3.854)

 

Barman S, Li X, Haigh S, Kondrikov D, Mahboubi K, Bordan Z, Stepp DW, Zhou J, Wang Y, Weintraub DS, Traber P, Snider W, Jonigk D, Sullivan J, Crislip GR, Butcher JT, Thompson J, Su Y, Chen F, Fulton DJR. Galectin-3 is expressed in Vascular Smooth Muscle Cells and Promotes Pulmonary Hypertension through changes in Proliferation, Apoptosis and Fibrosis. Am J Physiol Lung Cell Mol Physiol. 2019; 316(5): L784-L797. doi: 10.1152/ajplung.00186.2018. (Impact Factor 2015: 4.47 / 5-year Impact Factor: 4.09)

 

Neubert L*, Borchert P*, Shin H, Linz F, Wagner WL, Warnecke G, Laenger F, Haverich A, Stark H, Hoeper MM, Kuehnel M, Ackermann M°, Jonigk D°. Comprehensive Three-dimensional Morphology of Neoangiogenesis in Pulmonary Veno-occlusive Disease and Pulmonary Capillary Hemangiomatosis. J Pathol Clin Res 2019; 5(2): 108-114. doi: 10.1002/cjp2.125. (Impact Factor 2015: 7.381 / 5-year Impact Factor: n.a)

                *shared first author, °shared last author

 

Zimpfer A, Schneider B, Blanck O, Riedel K, Zhivov A, Jonigk D, Erbersdobler A, Jünemann A, Andratschke N, Hildebrandt G, Guthoff RF, Kakkassery V. Pathologic Features of Tumor Activity and Stability in Uveal Melanoma Specimens after Fractionated CyberKnife Radiosurgery. Pathol Oncol Res 2019; 25(2): 731-740. doi: 10.1007/s12253-018-00565-1. (Impact Factor 2017: 1.935 / 5-year impact Factor: 1.808 )

 

Lippmann T, Braubach P, Ettinger M, Kuehnel MP, Länger F, Jonigk D. Fluorescence in situ hybridisation (FISH) for diagnosis of periprosthetic joint infection in formalin-fixed paraffin-embedded surgical tissues. J Bone Joint Surg Am. 2019; 101(2): e5. doi: 10.2106/JBJS.18.00243. (Impact Factor 2017: 4.583 / 5-year Impact Factor: 6.416)

 

Serban KA, Mikosz A, Strange C, Janciauskiene SM, Stolk J, Jonigk D, Sandhaus RA, Petrache I. Lectin Complement Pathway in Emphysema. Am J Respir Crit Care Med. 2019; 199(5): 659-661. doi: 10.1164/rccm.201807-1380LE. (Impact Factor 2017: 15.239 / 5-year impact Factor: 13.077)

 

Renne J, Gutberlet M, Voskrebenzev A, Kern A, Kaireit T, Hinrichs J, Zardo P, Warnecke G, Krüger M, Braubach P, Jonigk D, Haverich A, Wacker F, Vogel-Claussen J, Zinne N. Multiparametric MRI for organ quality assessment in a porcine Ex-Vivo lung perfusion system. PLoS ONE 2018; 13(12): e0209103. doi: 10.1371/journal.pone.0209103. (Impact Factor 2017: 2.766 / 5-year impact Factor: 2.96)

 

Ackermann M, Kempf H, Hetzel M, Hesse C, Rafiei Hashtchin A, Brinkert K, Schott J, Haake K, Kühnel MP, Glage S, Ferreira de Figueiredo CS, Jonigk D, Sewald K, Schambach A, Wronski S, Moritz T, Martin U, Zweigerdt R, Munder A. Bioreactor-based mass production of human iPSC-derived macrophages enables immunotherapies against bacterial airway infections. Nat Commun 2018; 9(1): 5088. doi: 10.1038/s41467-018-07570-7. (Impact Factor 2017: 12.353 / 5-year impact Factor: 13.691)

 

Danov O, Jiménez Delgado SM, Obernolte H, Seehase S, Dehmel S, Braubach P, Fieguth HG, Matschiner G, Fitzgerald M, Jonigk D, Knauf S, Pfennig O, Warnecke G, Wichmann J, Braun A, Sewald K. Human lung tissue provides highly relevant data about efficacy of new anti-asthmatic drugs. PLoS ONE 2018; 13(11): e0207767. doi: 10.1371/journal.pone.0207767. (Impact Factor 2017: 2.766 / 5-year impact Factor: 2.965)

 

Figueiredo C, Carvalho Oliveira M, Chen-Wacker C, Jansson K, Höffler K, Yuzefovych Y, Pogozhykh O, Jin Z, Kühnel MP, Jonigk D, Wiegmann B, Sommer W, Haverich A, Warnecke G, Blasczyk R. Immunoengineering of the vascular endothelium to silence MHC expression during normothermic ex vivo lung perfusion. Hum Gene Ther 2018. doi: 10.1089/hum.2018.117. (Impact Factor 2017: 4.241/ 5-year impact Factor: 4.174)

 

Sommer W, Salman J, Avsar M, Hoeffler HK, Jansson K, Siemeni Monthe NT, Knoefel AK, Ahrens L, Poyanmehr R, Tudorache I, Braubach P, Jonigk D, Haverich A, Warnecke G. Prediction of transplant outcome after 24-hour ex vivo lung perfusion using the Organ Care System in a porcine lung transplantation model. Am J Transplant. 2019; 19(2): 345-355. doi: 10.1111/ajt.15075 (Impact Factor 2017: 6.493 / 5-year Impact Factor: 6.222)

 

Eickhoff L, Golpon H, Zardo P, Suhling H, Welte T, Jonigk D, Gottlieb J, Fuehner T. Endobronchial Ultrasound in Suspected Non-Malignant Mediastinal Lymphadenopathy. Pneumologie 2018; 72(8): 559-567. doi: 10.1055/a-0583-0265. (Impact Factor 2015: 0.48 / 5-year Impact Factor: 0.462)

 

Salman J, Jansson K, Siemeni T, Sommer W, Knoefel AK, Ahrens L, Nakagiri T, Ius F, Tudorache I, Kruse B, Thissen S, Jonigk D, Strüber M, Haverich A, Warnecke G, Avsar M. Role for primary immunosuppression with everolimus after pulmonary transplantation. Transpl Immunol 2018; 49: 12-19. doi: 10.1016/j.trim.2018.03.005. (Impact Factor 2016: 1.780 / 5-year Impact Factor: 1.731)

 

Legchenko E, Chouvarine P, Borchert P, Fernandez-Gonzalez A, Snay E, Meier M, Maegel L, Mitsialis S.A, Rog-Zielinska E, Kourembanas S, Jonigk D, Hansmann G. The PPARγ Agonist Pioglitazone Reverses Pulmonary Hypertension and Prevents Right Heart Failure through Fatty Acid Oxidation. Sci Transl Med 2018; 10(438). doi: 10.1126/scitranslmed.aao0303. (Impact Factor 2016: 16.761 / 5-year Impact Factor: 17.136)

 

Teiken K, Kuehnel MP, Rehkaemper J, Kreipe H, Laenger F, Hussein K, Jonigk D. Non-canonical WNT6/WNT10a Signal Factor Expression in EBV+ Post-transplant Smooth Muscle Tumors. Clin Sarcoma Res 2018; 8: 10. doi: 10.1186/s13569-018-0096-8. (Impact Factor 2015: 2.22 / 5-year Impact Factor: n.a.)

 

Diestelhorst J, Junge N, Jonigk D, Schlue J, Falk C, Manns MP, Baumann U, Jaeckel E, Taubert R. Baseline IL-2 and the AIH score can predict the response to standard therapy in paediatric autoimmune hepatitis. Sci Rep 2018; 8(1): 419. doi: 10.1038/s41598-017-18818-5. (Impact Factor 2016: 4.259 / 5-year Impact Factor: 4.847)

 

Neehus AL, Lam J, Haake K, Merkert S, Schmidt N, Mucci A, Ackermann M, Schubert M, Happle C, Kühnel MP, Blank P, Philipp F, Goethe R, Jonigk D, Martin U, Kalinke U, Baumann U, Schambach A, Roesler J, Lachmann N. Impaired IFNγ-Signaling and Mycobacterial Clearance in IFNγR1-Deficient Human iPSC-Derived Macrophages. Stem Cell Reports 2018; 10(1): 7-16. doi: 10.1016/j.stemcr.2017.11.011. (Impact Factor 2016: 7.338 / 5-year Impact Factor: 7.508)

 

Hetzel M, Mucci A, Blank P, Hai Ha Nguyen A, Schiller J, Halle O, Kühnel MP, Billig S, Meineke R, Brand D, Herder V, Baumgärtner W, Bange FC, Goethe R, Jonigk D, Förster R, Gentner B, Casanova JL, Bustamante J, Schambach A, Kalinke U, Lachmann N. Hematopoietic stem cell gene therapy for IFNγR1 deficiency protects mice from mycobacterial infections. Blood 2018; 131(5): 533-545. doi: 10.1182/blood-2017-10-812859. (Impact Factor 2016: 13.164 / 5-year Impact Factor: 10.891)

 

Neuhaus V, Danov O, Konzok S, Obernolte H, Dehmel S, Braubach P, Jonigk D, Fieguth H-G, Zardo P, Warnecke G, Martin C, Braun A, Sewald K. Assessment of the Cytotoxic and Immunomodulatory Effects of Substances in Human Precisioncut Lunge Slices. J Vis Exp 2018; 9(135). doi: 10.3791/57042. (Impact Factor 2016: 1.232 / 5-year Impact Factor: 1.659)

 

Ackermann M, Gaumann A, Mentzer SJ, Hinrichs JB, Warnecke G, Hoeper MM, Braubach P, Kuehnel M, Mägel L, Jonigk D. Plexiform vasculopathy in chronic thromboembolic pulmonary hypertension. Am J Respir Crit Care Med 2017; 196(8). doi: 10.1164/rccm.201703-0591IM. (Impact Factor 2016: 13.204 / 5-year Impact Factor: 11.946)

 

Aichler M, Kunzke T, Buck A, Sun N, Ackermann M, Jonigk D, Gaumann A, Walch A. Molecular similarities and differences from human pulmonary fibrosis and corresponding mouse model - MALDI imaging mass spectrometry in comparative medicine. Lab Invest 2017; 98(1): 141-149. doi: 10.1038/labinvest.2017.110. (Impact Factor 2016: 4.857 / 5-year Impact Factor: 4.648)

 

Hess R, Wujak L, Hesse C, Sewald K, Jonigk D, Warnecke G, Fieguth H, Demaat S, Maas C, Bonella F, Preissner KT, Weiss B, Schaefer L, Kuebler W, Markart P, Wygrecka M. Coagulation factor XII regulates inflammatory responses in human lungs. Thromb Haemost 2017; 117(10): 1896-1907. doi: 10.1160/TH16-12-0904. (Impact Factor 2016: 5.627 / 5-year Impact Factor: 5.538)

 

Braubach P, Lippmann T, Raoult D, Lagier J, Anagnostopoulos I, Zender S, Länger FP, Kreipe H, Kühnel MP, Jonigk D. Fluorescence in situ hybridisation for diagnosis of Whipple’s disease in formalin-fixed paraffin-embedded tissue. Front Med (Lausanne) 2017; 4: 87. doi: 10.3389/fmed.2017.00087. (Impact Factor 2016: 4.076 / 5-year Impact Factor: 4.502)

 

Taubert R, Wolenski M, Noyan F, Jonigk D, Schlue J, Krech T, Lichtinghagen R, Falk C, Schlaphoff V, Bantel H, Muratori L, Manns M, Jaeckel E. Hyperferritinemia and hypergammaglobulinemia predict the treatment response to standard therapy in autoimmune hepatitis. PLoS ONE 2017; 12(6): e0179074. doi: 10.1371/journal.pone.0179074. (Impact Factor 2016: 3.54 / 5-year Impact Factor: 4.112)

 

Wujak L, Hesse C, Sewald K, Jonigk D, Braubach P, Warnecke G, Fieguth HG, Braun A, Lochnit G, Markart P,Schaefer L, Wygrecka M. FXII promotes proteolytic processing of the LRP1 ectodomain. BBA - General Subjects 2017; 1861(8): 2088-2098. doi: 10.1016/j.bbagen.2017.05.023. (Impact Factor 2016: 5.083 / 5-year Impact Factor: 4.805)

 

Neuhaus V, Schaudien D, Golovina T, Temann UA, Thompson C, Lippmann T, Bersch C, Pfennig O, Jonigk D, Braubach P, Fieguth HG, Warnecke G, Yusibov V, Sewald K, Braun A. Assessment of long-term cultivated human precision-cut lung slices as an ex vivo system for
evaluation of chronic cytotoxicity and functionality. J Occup Med Toxicol 2017; 12: 13. doi: 10.1186/s12995-017-0158-5. (Impact Factor 2015/2016: 1.486 / 5-year Impact Factor: 2.17)

 

Jeinsen N*, Mägel L, Jonigk D, Klingenberg M, Haverich A, Wilhelmi M, Böer U. Biocompatibility of intensified decellularized equine carotid arteries in a rat subcutaneous implantation model and in a human in vitro-model. Tissue Eng Part A 2017; 24(3-4): 310-321. doi: 10.1089/ten.TEA.2016.0542. (Impact Factor 2015/2016: 3.58 / 5-year Impact Factor: 4.482)

 

Calvier L, Chouvarine P, Legchenko E, Hoffmann N, Geldner J, Borchert P, Jonigk D, Mozes MM, Hansmann G. PPARγ Links BMP2 and TGFβ1 Pathways in Vascular Smooth Muscle Cells, Regulating Cell Proliferation and Glucose Metabolism. Cell Metab 2017; 25(5): 1118-1134.e7. doi: 10.1016/j.cmet.2017.03.011. (Impact Factor 2016: 17.303 / 5-year Impact Factor: 16.707)

 

Karadagi A, Johansson H, Zemack H, Salipalli S, Mörk L, Kannisto K, Jorns C, Stokkeland K, Gramignoli R, Strom S, Ericzon B, Jonigk D, Janciauskiene S, Nowak G, Ellis E. Exogenous alpha 1-antitrypsin down-regulates SERPINA1 expression. PLoS ONE 2017; 12(5): e0177279. doi: 10.1371/journal.pone.0177279. (Impact Factor 2016: 3.54 / 5-year Impact Factor: 4.112)

 

Jansson K, Dreckmann K, Sommer W, Avsar M, Salman J1, Siemeni T, Knöfel AK, Pauksch L, Gottlieb J, Frühauf J, Werner M, Jonigk D, Strüber M, Haverich A, Warnecke G. Splenocyte infusion and whole body irradiation for induction of peripheral tolerance in porcine lung transplantation: modifications of the preconditioning regime for improved clinical feasibility. Transplantation Direct 2017; 3(7): e170. doi: 10.1097/TXD.0000000000000689. (Impact Factor 2016: n.a. / 5-year Impact Factor: n.a.)

 

Dommaschk A, Ding N, Tort Tarres M, Bittersohl LF, Maus R, Stolper J, Jonigk D, Braubach P, Lippmann T, Welte T, Maus UA. Nasopharyngeal colonization with Streptococcus pneumoniae triggers dendritic cell-dependent antibody responses against invasive disease in mice. Eur J Immunol 2017; 47(3): 540-551. doi: 10.1002/eji.201646700. (Impact Factor 2016: 4.179 / 5-year Impact Factor: 4.172)

 

Sommer W, Buechler G, Jansson K, Avsar M, Knöfel A, Salman J, Hoeffler K, Siemeni T, Gottlieb J, Karstens JH, Jonigk D, Reising A, Haverich A, Strüber M, Warnecke G. Irradiation before and donor splenocyte infusion immediately after transplantation induce tolerance to lung, but not heart allografts in miniature swine. Transpl Int 2017; 30(4): 420-431. doi: 10.1111/tri.12916. (Impact Factor 2016: 3.079 / 5-year Impact Factor: 2.9205)

 

Zhang R, Maegel L, Jonigk D, Laenger F, Lippmann T, Zardo P, Poelzing F. Biosynthetic Nanostructured Cellulose Patch for Chest Wall Reconstruction: Five-Month Follow-up in a Porcine Model. J Invest Surg 2017; 30(5): 297-302. doi: 10.1080/08941939.2016.1244310. (Impact Factor 2016: 0.76 / 5-year Impact Factor: 0.944)

 

Behler-Janbeck F, Takano T, Maus R, Stolper J, Jonigk D, Tarrés MT, Fuehner T, Prasse A, Welte T, Timmer MSM, Stocker BL, Nakanishi Y, Miyamoto T, Yamasaki S, Maus UA. C-type lectin Mincle recognizes glucosyl-diacylglycerol of Streptococcus pneumoniae and plays a protective role in pneumococcal pneumonia. PLoS Pathog 2016; 12(12): e1006038. doi: 10.1371/journal.ppat.1006038. (Impact Factor 2016: 7.64 / 5-year Impact Factor: n.a.)

 

Jonigk D, Rath B, Borchert P, Braubach P, Maegel L, Izykowski N, Warnecke G, Sommer W, Kreipe H, Blach R, Anklamm A, Haverich A, Eder M, Stadler M, Welte T, Gottlieb J, Kuehnel M, Laenger F. Comparative Analysis of Morphological and Molecular Motifs in Bronchiolitis Obliterans and Alveolar Fibroelastosis after Lung and Stem Cell Transplantation. J Pathol Clin Res 2016; 3(1): 17-28. doi: 10.1002/cjp2.60. (Impact Factor 2015: 7.381 / 5-year Impact Factor: n.a)

 

Christgen M, van Luttikhuizen JL, Raap M, Braubach P, Schmidt L, Jonigk D, Feuerhake F, Lehmann U, Schlegelberger B, Kreipe HH, Steinemann D. Precise ERBB2 copy number assessment in breast cancer by means of molecular inversion probe array analysis. Oncotarget 2016; 7(50): 82733-82740. doi: 10.18632/oncotarget.12421. (Impact Factor 2014: 6.359 / 5-year Impact Factor: 6.368)

 

Weissinger E, Human C, Metzger J, Hambach L, Wolff D, Greinix H, Dickinson A, Mullen W, Jonigk D, Kuzmina Z, Kreipe H, Schweier P, Boehm O, Turuchanow I, Ihlenburg-Schwarz D, Raad J, Durban A, Schiemann M, Koenecke C, Diedrich H, Holler E, Beutel G, Krauter J, Ganser A, Stadler M. The proteome pattern cGvHD_MS14 allows early and accurate prediction of chronic GvHD after allogeneic stem cell transplantation. Leukemia 2016; 31(3): 654-662. doi: 10.1038/leu.2016.259. (Impact Factor 2015: 4.33 / 5-year Impact Factor: 7.064)

 

Poehnert D, Grethe L, Maegel L, Jonigk D, Lippmann T, Kaltenbirn A, Schrem H, Klempnauer J, Winny M. Evaluation of the Effectiveness of Peritoneal Adhesion Prevention Devices in a Rat Model. Int J Med Sci 2016; 13(7): 524-32. doi: 10.7150/ijms.15167. (Impact Factor 2015: 2.59 / 5-year Impact Factor: 1.952)

 

Winny M, Maegel L, Grethe LV, Jonigk D, Borchert P, Kaltenborn A, Schrem H, Klempnauer J, Poehnert D. Treatment of de-peritonealized intestine with 4DryField® PH prevents adhesions between non-resorbable intra-peritoneal hernia mesh and bowel. Am J Transl Res 2016; 8(12): 5706-5714. (Impact Factor 2016: 2.829 / 5-year Impact Factor: 3.146)

 

Dabral S, Tian X, Kojonazarov B, Savai R, Ghofrani HA, Weissmann N, Florio M, Sun J, Jonigk D, Maegel L, Grimminger F, Seeger W, Savai Pullamsetti S, Schermuly RT. Notch1 signalling regulates endothelial proliferation and apoptosis in pulmonary arterial hypertension. Eur Respir J 2016; 48(4): 1137-1149. doi: 10.1183/13993003.00773-2015. (Impact Factor 2015: 7.636 / 5-year Impact Factor: 6.86)

 

Siemeni T, Knoefel AK, Madrahimov N, Sommer W, Avsar M, Salman J, Ius F, Frank N, Buechler G, Jonigk D, Jansson K, Maus U, Tudorache I, Falk CS, Haverich A, Warnecke G. In Vivo Development of Transplant Arteriosclerosis in Humanized Mice Reflects Alloantigen Recognition and Periphal Treg Phenotype of Lung Transplant Recipients. Am J Transplant 2016; 16(11): 3150-3162. doi: 10.1111/ajt.13905. (Impact Factor 2015: 4.21 / 5-year Impact Factor: 5.046)

 

Izykowski N, Kuehnel M, Hussein K, Mitschke K, Gunn M, Janciauskiene S, Haverich A, Warnecke G, Laenger F, Maus U, Jonigk D. Organizing Pneumonia in Mice and Men. J Transl Med 2016; 14(1): 169. doi: 10.1186/s12967-016-0933-6. (Impact Factor 2015: 3.93 / 5-year Impact Factor: 4.13)

 

Winny M, Maegel L, Grethe L, Lippmann T, Jonigk D, Schrem H, Kaltenborn A, Klempnauer J, Poehnert D. Adhesion Prevention Efficacy of Composite Meshes Parietex®, Proceed® and 4DryField® PH Covered Polypropylene Meshes in an IPOM Rat Model. Int J Med Sci 2016; 13(12): 936-941. (Impact Factor 2016: 2.399 / 5-year Impact Factor:2.232)

 

Krueger M, Zinne N, Biancosino C, Hoeffler K, Rajab TK, Waldmann KH, Jonigk D, Avsar M, Haverich A, Hoeltig D. Porcine pulmonary auto-transplantation for ex vivo therapy as a model for new treatment strategies. Interact Cariovasc Thorac Surg 2016; 23(3): 358-66. doi: 10.1093/icvts/ivw160. (Impact Factor 2015: 1.155 / 5-year Impact Factor: 1.597)

 

Kellner M, Heidrich M, Lorbeer RA, Antonopoulos GC, Knudsen L, Wrede C, Izykowski N, Grothausmann R, Jonigk D, Ochs M, Ripken T, Kühnel MP, Meyer H. A combined method for correlative 3D imaging of biological samples from macro to nano scale. Sci Rep 2016; 6: 35606. doi: 10.1038/srep35606. (Impact Factor 2016: 4.259 / 5-year Impact Factor: 5.228)

 

Gren ST, Janciauskiene S, Sandeep S, Jonigk D, Kvist PH, Gerwien JG, Hakansson K, Grip O. The protease inhibitor cystatin C down-regulates the release of IL-β and TNF-α in lipopolysaccharide activated monocytes. J Leukoc Biol 2016; 100(4): 811-822. (Impact Factor 2015: 4.289 / 5-year Impact Factor: 4.556)

 

Winny M, Grethe L, Maegel L, Jonigk D, Lippmann T, Klempnauer J, Poehnert D. Impairment of the Peritoneal Surface as a Decisive Factor for Intestinal Adhesions in Intraperitoneal Onlay Mesh Surgery - Introducing a New Rat Model. Int J Med Sci 2016; 13(2): 108-12. doi: 10.7150/ijms.14056. (Impact Factor 2015: 2.003 / 5-year Impact Factor: 1.966)

 

Rafikova O, Rafikov R, Kangath A, Qu N, Aggarwal S, Sharma S, Desai J, Fields T, Ludewig B, Yuan JX, Jonigk D, Black SM. Redox regulation of epidermal growth factor receptor signaling during the development of pulmonary hypertension. Free Radic Biol Med 2016; 95: 96-111. doi: 10.1016/j.freeradbiomed.2016.02.029 (Impact Factor 2015: 5.736 / 5-year Impact Factor: 5.569)

 

Leo F, Bartels S, Maegel L, Framke T, Buesche G, Jonigk D, Christgen M, Lehmann U, Kreipe H. Prognostic factors in the myoepithelial-like spindle cell type of metaplastic breast cancer. Virchows Arch 2016; 469(2): 191-201. doi: 10.1007/s00428-016-1950-9. (Impact Factor 2013: 2.676 / 5-year Impact Factor: 2.655)

 

Olsson KM, Olle S, Fuge J, Welte T, Hoeper MM, Lerch C, Maegel L, Haller H, Jonigk D, Schiffer L. CXCL13 in idiopathic pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension. Respir Res 2016; 17: 21. doi: 10.1186/s12931-016-0336-5. (Impact Factor 2015: 3.093 / 5-year Impact Factor: 3.313)

 

Derlin T, Jonigk D, Bauersachs J, Bengel F. Molecular imaging of chemokine receptor CXCR4 in non-small cell lung cancer using 68Ga-Pentixafor PET/CT: comparison with 18F-FDG. Clin Nucl Med 2016; 41(4): e204-5. doi: 10.1097/RLU.0000000000001092. (Impact Factor 2014: 3.931 / 5-year Impact Factor: 3.504)

 

Avsar M, Jansson K, Sommer W, Kruse B, Thissen S, Dreckmann K, Knoefel AK, Salman J, Hafer C, Hecker J, Buechler G, Karstens JH, Jonigk D, Länger F, Kaever V, Falk CS, Hewicker-Trautwein M, Ungefroren H, Haverich A, Strüber M, Warnecke G. Augmentation of Transient Donor Cell Chimerism and Alloantigen-Specific Regulation of Lung Transplants in Miniature Swine. Am J Transplant 2016; 16(5): 1371-82. doi: 10.1111/ajt.13629. (Impact Factor 2014: 5.683 / 5-year Impact Factor: 5.717)

 

Schieck M, Schouten JP, Michel S, Suttner K, Toncheva AA, Gaertner V, Illig T, Lipinski S, Franke A, Klintschar M, Kalayci O, Sahiner UM, Birben E, Melén E, Pershagen G, Freidin MB, Ogorodova LM, Granell R, Henderson J, Brunekreef B, Smit HA, Vogelberg C, von Berg A, Bufe A, Heinzmann A, Laub O, Rietschel E, Simma B, Genuneit J, Jonigk D, Postma DS, Koppelman GH, Vonk JM, Timens W, Boezen HM, Kabesch M. Doublesex and mab-3 related transcription factor 1 (DMRT1) is a sex-specific genetic determinant of childhood onset asthma and is expressed in testis and macrophages. J Allergy Clin Immun 2016; 138(2): 421-31. doi: 10.1016/j.jaci.2015.12.1305. (Impact Factor 2014: 11.476 / 5-year Impact Factor: 10.715)

 

Watermann I, Schmitt B, Stellmacher F, Müller J, Gaber R, Kugler C, Reinmuth N, Huber RM, Thomas M, Zabel P, Rabe KF, Jonigk D, Warth A, Vollmer E, Reck M, Goldmann T. Improved diagnostics targeting c-MET in non-small cell lung cancer: expression, amplification and activation? Diagn Pathol 2015; 10: 130. doi: 10.1186/s13000-015-0362-5. (Impact Factor 2014: 2.597 / 5-year Impact Factor: 1.976)

 

Jonigk D, Izykowski N, Rische J, Braubach P, Kühnel M, Warnecke G, Lippmann T, Kreipe H, Haverich A, Welte T, Gottlieb J, Laenger F. Molecular Profiling in Lung Biopsies of Human Pulmonary Allografts to Predict Chronic Lung Allograft Dysfunction. Am J Pathol 2015; 185(12): 3178-88. doi: 10.1016/j.ajpath.2015.08.016. (Impact Factor 2014: 4.591 / 5-year Impact Factor: 4.766)

 

Zhang R, Bures M, Höffler HK, Jonigk D, Haverich A, Krüger M. In Vitro Lung Model Assessing the Efficacy of Surgical Sealants in Treating Alveolar Air Leaks. J Invest Surg 2015; 28(6): 323-7. doi: 10.3109/08941939.2015.1010023. (Impact Factor 2014: 1.158 / 5-year Impact Factor: 1.141)

 

Fuehner T, Clajus C, Fuge J, Jonigk D, Welte T, Haverich A, Greer M, Gottlieb J. Lung Transplantation after Endoscopic Lung Volume Reduction. Respiration 2015; 90(3): 243-50. doi: 10.1159/000434685. (Impact Factor 2014: 2.593 / 5-year Impact Factor: 2.587)

 

Kellner M, Wehling J, Warnecke G, Heidrich M, Izykowski N, Vogel-Claussen J, Lorbeer RA, Antonopoulos G, Janciauskiene S, Grothausmann R, Knudsen L, Ripken T, Meyer H, Kreipe H, Ochs M, Jonigk D*, Kühnel MP*. Correlating 3D morphology with molecular pathology: fibrotic remodelling in human lung biopsies. Thorax 2015; 70(12): 1197-8. doi: 10.1136/thoraxjnl-2015-207131. (Impact-Factor 2014: 8.290 / 5-year Impact Factor: 7.719)

*shared last author

 

Stammler A, Hau T, Bhushan S, Meinhardt A, Jonigk D, Lippmann T, Pilatz A, Schneider-Hüther I, Middendorff R. Epididymitis: ascending infection restricted by segmental boundaries. Hum Reprod 2015; 30(7): 1557-65. doi: 10.1093/humrep/dev112. (Impact Factor 2014: 4.569 / 5-year Impact Factor: 4.5312)

 

Rafikova O, Rafikov R, Meadows ML, Kangath A, Jonigk D, Black SM. The sexual dimorphism associated with pulmonary hypertension corresponds to a fibrotic phenotype. Pulm Circ 2015; 5(1): 184-97. doi: 10.1086/679724. (Impact Factor 2014: 2.66 / 5-year Impact Factor: n.a.)

 

Knippenberg S, Ueberberg B, Maus R, Bohling J, Ding N, Tort Tarres M, Hoymann HG, Jonigk D, Izykowski N, Paton JC, Ogunniyi AD, Lindig S, Bauer M, Welte T, Seeger W, Guenther A, Sisson TH, Gauldie J, Kolb M, Maus UA. Streptococcus pneumoniae triggers progression of pulmonary fibrosis through pneumolysin. Thorax 2015; 70(7): 636-46. doi: 10.1136/thoraxjnl-2014-206420. (Impact Factor 2014: 8.290 / 5-year Impact Factor: 7.719)

 

Sommer W, Knöfel AK, Madrahimov N, Avsar M, Jonigk D, Salman J, Dreckmann K, Jansson K, Haverich A, Warnecke G. Allogeneic CD4+CD25 high T cells regulate obliterative bronchiolitis of heterotopic bronchus allograft in both porcinized and humanized mouse models. Transplantation 2015; 99(3): 482-91. doi: 10.1097/TP.0000000000000632. (Impact Factor 2014: 3.781 / 5-year Impact Factor: 3.548)

 

Sommer W, Knöfel AK, Izykowski N, Oldhafer F, Avsar M, Jonigk D, Warnecke G, Haverich A. Physical exercise reduces transplant arteriosclerosis in a mouse aorta transplantation model. J Thorac Cardiovasc Surg 2015; 149(1): 330-7. doi: 10.1016/j.jtcvs.2014.10.029. (Impact Factor 2014: 3.526 / 5-year Impact Factor: 3.539)

 

Behler F, Maus R, Bohling J, Knippenberg S, Kirchhof G, Nagata M, Jonigk D, Izykowski N, Mägel L, Welte T, Yamasaki S, Maus UA. Macrophage-inducible C-type lectin Mincle expressing dendritic cells contribute to control splenic Mycobacterium bovis BCG infection in mice. Infect Immun 2015; 83(1): 184-96. doi: 10.1128/IAI.02500-14. (Impact Factor 2014: 4.074 / 5-year Impact Factor: 4.062)

 

Zhang R, Bures M, Höffler K, Jonigk D, Haverich A, Krueger M. In vitro comparison of two widely used surgical sealants for treating alveolar air leak. Thorac Cardiovasc Surg 2014; 62(8): 705-9. doi: 10.1055/s-0034-1389272 (Impact Factor 2013: 0.925 / 5-year Impact Factor: 0.805)

 

Abbas M, Ploch EM, Wehling J, Schipper E, Janciauskiene S, Kreipe HH, Jonigk D. α-Methylacyl-coenzyme A racemase (AMACR, p504s) is a marker to distinguish malignant melanomas from dysplastic nevi and melanocytic nevi. Tumor Biol 2014; 35(12): 12015-20. doi: 10.1007/s13277-014-2500-1. (Impact Factor 2013: 2.518 / 5-year Impact Factor: 2.316)

 

Hussein K, Rath B, Ludewig B, Kreipe H, Jonigk D. Clinico-pathological characteristics of different types of immunodeficiency-associated smooth muscle tumours. Eur J Cancer 2014; 50(14): 2417-24. doi: 10.1016/j.ejca.2014.06.006. (Impact Factor 2013: 5.061 / 5-year Impact Factor: 5.257)

 

Barman S, Chen F, Su Y, Dimitropoulou C, Wang Y, Catravas J, Han W, Orfi L, Szantai-Kis C, Keri G, Szabadkai I, Barabutis N, Black S, Jonigk D, Giannis A, Asmis R, Stepp D, Ramesh G, Rafikova O, Rafikov R, Fulton D. NADPH oxidase 4 is expressed in pulmonary artery adventitia and contributes to hypertensive vascular remodeling. Arterioscler Thromb Vasc Bio 2014; 34(8): 1704-15. doi: 10.1161/ATVBAHA.114.303848. (Impact Factor 2013: 6.338 / 5-year Impact Factor: 6.986)

 

Alam S, Li Z, Atkinson C, Jonigk D, Janciauskiene S, Mahadeva R. Z alpha-1 antitrypsin confers a pro-inflammatory phenotype that contributes to COPD. Am J Respir Crit Care Med 2014; 189(8): 909-31. doi: 10.1164/rccm.201308-1458OC. (Impact Factor 2013: 11.041 / 5-year Impact Factor: 10.919)

 

Liessem S, Winkens W, Jonigk D, Wasielewski R, Fisseler-Eckhoff A, Rüschoff J, Kreipe HH. Determination of tumor biological parameters in breast cancer: round robin testing for quality assurance. Pathologe 2014; 35(1):61-71. doi: 10.1007/s00292-013-1837-3. (Impact Factor 2013: 0.621 / 5-year Impact Factor: 0.6)

 

Aggarwal S, Gross CM, Rafikov R, Kumar S, Fineman JR, Ludewig B, Jonigk D, Black SM. Nitration of tyrosine 247 inhibits protein kinase G-1α activity by attenuating cyclic guanosine monophosphate binding. J Biol Chem 2014; 289(11): 7948-61. doi: 10.1074/jbc.M113.534313. (Impact Factor 2013: 4.651 / 5-year Impact Factor: 5.023)

 

Abbas M, Salem J, Stucki-Koch A, Rickmann M, Grünwald V, Herrmann T, Jonigk D, Kreipe H, Hussein K. Expression of angiogenic factors is increased in metastasised renal cell carcinomas. Virchows Arch 2014; 464(2): 197-202. doi: 10.1007/s00428-013-1529-7. (Impact Factor 2013: 2.676 / 5-year Impact Factor: 2.655)

 

Jonigk D, Izykowski N, Maegel L, Schormann E, Ludewig B, Kreipe H, Hussein K. Tumour angiogenesis in Epstein-Barr virus-associated post-transplant smooth muscle tumours. Clin Sarcoma Res 2014; 4(1): 1. doi: 10.1186/2045-3329-4-1. (Impact Factor 2013: 5.2 / 5-year Impact Factor: n.a.)

 

Atanasova S, Hirschburger M, Jonigk D, Obert M, Petri K, Evers A, Hecker A, Schmitz J, Kaufmann A, Wilhelm J, Chakraborty T, Warnecke G, Gottlieb J, Padberg W, Grau V. A relevant experimental model for human bronchiolitis obliterans syndrome. J Heart Lung Transplant 2013; 32(11): 1131-9. doi: 10.1016/j.healun.2013.07.016. (Impact Factor 2013: 5.112 / 5-year Impact Factor: 3.627)

 

Hussein K, Maecker-Kolhoff B, Donnerstag F, Laenger F, Kreipe H, Jonigk D. Epstein-barr virus-associated smooth muscle tumours after transplantation, infection with human immunodeficiency virus and congenital immunodeficiency syndromes. Pathobiology 2013; 80(6): 297-301. doi: 10.1159/000351326. (Impact Factor 2013: 1.948 / 5-year Impact Factor: 2)

 

Jonigk D, Al-Omari M, Maegel L, Müller M, Izykowski N, Hong J, Hong K, Kim SH, Dorsch M, Mahadeva R, Laenger F, Kreipe H, Braun A, Shahaf G, Lewis EC, Welte T, Dinarello CA, Janciauskiene S. Anti-inflammatory and immunomodulatory properties of α1-antitrypsin without inhibition of elastase. Proc Natl Acad Sci USA 2013; 110(37): 15007-12. doi: 10.1073/pnas.1309648110. (Impact Factor 2013: 9.737 / 5-year Impact Factor: 10.6)

 

Neuhaus V, Schwarz K, Klee A, Seehase S, Förster C, Pfennig O, Jonigk D, Fieguth HG, Koch W, Warnecke G, Yusibov V, Sewald K, Braun A. Functional testing of an inhalable nanoparticle based influenza vaccine using a human precision cut lung slice technique. PLoS ONE 2013; 8(8): e71728. doi: 10.1371/journal.pone.0071728. (Impact Factor 2013: 3.73 / 5-year Impact Factor: 4.244)

 

Jonigk D, Izykowski N, Maegel L, Schormann E, Maecker-Kolhoff B, Laenger F, Kreipe H, Hussein K. MicroRNA expression in Epstein-Barr virus-associated post-transplant smooth muscle tumours is related to leiomyomatous phenotype. Clin Sarcoma Res 2013; 3(1): 9. doi: 10.1186/2045-3329-3-9. (Impact Factor 2013: 5.2 / 5-year Impact Factor: n.a.)

 

V Laffert M, Warth A, Penzel R, Schirmacher P, Jonigk D, Kreipe H, Schildhaus HU, Merkelbach-Bruse S, Büttner R, Reu S, Kerler R, Jung A, Kirchner T, Wölfel C, Petersen I, Rodriguez R, Jochum W, Bartsch H, Fisseler-Eckhoff A, Berg E, Lenze D, Dietel M, Hummel M. Anaplastic lymphoma kinase (ALK) gene rearrangement in non-small cell lung cancer (NSCLC): results of a multi-centre ALK-testing. Lung Cancer 2013; 81(2): 200-6. doi: 10.1016/j.lungcan.2013.04.015. (Impact Factor 2013: 3.392 / 5-year Impact Factor: 3.457)

 

Hauck G, Jonigk D, Göhring G, Kreipe H, Hussein K. Myelofibrosis in Philadelphia chromosome-negative myeloproliferative neoplasms is associated with aberrant karyotypes. Cancer Genet 2013; 206(4): 116-23. doi: 10.1016/j.cancergen.2013.02.002. (Impact Factor 2013: 1.915 / 5-year Impact Factor: 1.915)

 

Warth A, Fink L, Fisseler-Eckhoff A, Jonigk D, Keller M, Ott G, Rieker RJ, Sinn P, Söder S, Soltermann A, Willenbrock K, Weichert W. Pulmonary Pathology Working Group of the German Society of Pathology. Interobserver agreement of proliferation index (Ki-67) outperforms mitotic count in pulmonary carcinoids. Virchows Arch 2013; 462(5): 507-13. doi: 10.1007/s00428-013-1408-2. (Impact Factor 2013: 2.676 / 5-year Impact Factor: 2.655)

 

Böer U, Spengler C, Jonigk D, Klingenberg M, Schrimpf C, Lützner S, Harder M, Kreipe HH, Haverich A, Wilhelmi M. Coating decellularized equine carotid arteries with CCN1 improves cellular repopulation, local biocompatibility, and immune response in sheep. Tissue Eng Part A 2013; 19(15-16): 1829-42. doi: 10.1089/ten.TEA.2012.0558. (Impact Factor 2013: 4.065 / 5-year Impact Factor: 4.623)

 

Böer U, Spengler C, Klingenberg M, Jonigk D, Harder M, Kreipe HH, Haverich A, Wilhelmi M. Cytotoxic effects of polyphexanide on cellular repopulation and calcification of decellularized equine carotids in vitro and in vivo. Int J Artif Organs 2013; 36(3): 184-94. doi: 10.5301/IJAO.5000182. (Impact Factor 2013: 1.759 / 5-year Impact Factor: 1.54)

 

Rafikova O, Rafikov R, Kumar S, Sharma S, Aggarwal S, Schneider F, Jonigk D, Black SM, Tofovic SP. Bosentan inhibits oxidative and nitrosative stress and rescues occlusive pulmonary hypertension. Free Radic Biol Med 2013; 56: 28-43. doi: 10.1016/j.freeradbiomed.2012.09.013. (Impact Factor 2013: 5.271 / 5-year Impact Factor: 5.969)

 

Pilatz A, Altinkilic B, Schormann E, Maegel L, Izykowski N, Becker J, Weidner W, Kreipe H, Jonigk D. Congenital Phimosis With and Without Lichen Sclerosus: Distinct Expression Patterns of Tissue Remodeling-Associated Genes. J Urol 2013; 189(1): 268-74. doi: 10.1016/j.juro.2012.09.010. (Impact Factor 2013: 3.696 / 5-year Impact Factor: 3.914)

 

Hauck G, Jonigk D, Kreipe H, Hussein K. Simultaneous and sequential concurrent myeloproliferative and lymphoproliferative neoplasms. Acta Haematologica 2012; 129(3): 187-96. doi: 10.1159/000342484. (Impact Factor 2013: 0.894 / 5-year Impact Factor: 1.125)

 

Neumann D, Beermann S, Maegel L, Jonigk D, Weber-Steffens D, Maennel D, Seifert R. Problems associated with the use of commercial and non-commercial antibodies against the histamine H4-receptor. Naunyn-Schmiedeberg's Archives of Pharmacology. 2012; 385(9): 855-60. doi: 10.1007/s00210-012-0766-7. (Impact Factor 2013: 2.147 / 5-year Impact Factor: 2.23)

 

Koczulla R*, Jonigk D*, Wolf T, Herr C, Noeske S, Klepetko W, Vogelmeier C, von Neuhoff N, Rische J, Wrenger S, Golpon H, Voswinckel R, Luisetti M, Ferrarotti I, Welte T, Janciauskiene S. Kruppel-like zinc finger proteins in end-stage COPD lungs with and without severe alpha1-antitrypsin deficiency. Orphanet J Rare Dis 2012; 7:29. doi: 10.1186/1750-1172-7-29. (Impact Factor 2013: 4.315 / 5-year Impact Factor: 5.715)

* shared first author

 

Bockmeyer CL, Maegel L, Janciauskiene S, Rische J, Lehmann U, Maus UA, Nickel N, Haverich A, Hoeper MM, Golpon HA, Kreipe H, Laenger F, Jonigk D. Plexiform vasculopathy of severe pulmonary arterial hypertension and microRNA expression. J Heart Lung Transplant 2012; 31(7): 764-72. doi: 10.1016/j.healun.2012.03.010. (Impact Factor 2013: 5.112 / 5-year Impact Factor: 3.627)

 

Hadem J, Bockmeyer CL, Lukasz A, Pischke S, Schneider AS, Wedemeyer H, Jonigk D, Manns MP, Kumpers P. Angiopoietin-2 in acute liver failure. Crit Care Med. 2012; 40(5): 1499-505. doi: 10.1097/CCM.0b013e318241e34e. (Impact Factor 2013: 6.124 / 5-year Impact Factor: 6.401)

 

Jonigk D, Laenger F, Maegel L, Izykowski N, Rische J, Tiede C, Klein C, Maecker-Kolhoff B, Kreipe H, Hussein K. Molecular and Clinicopathological Analysis of Epstein-Barr Virus-Associated Posttransplant Smooth Muscle Tumors. Am J Transplant 2012; 12(7): 1908-17. doi: 10.1111/j.1600-6143.2012.04011.x. (Impact Factor 2013: 6.192 / 5-year Impact Factor: 6.014)

 

Pilatz A, Altinkilic B, Rusz A, Izykowski N, Traenkenschuh W, Rische J, Lehmann U, Herbst C, Maegel L, Becker J, Weidner W, Jonigk D. Role of human papillomaviruses in persistent and feglucocorticoid-resistant juvenile phimosis. J Eur Acad Dermatol Venereol 2012; 27(6): 716-21. doi: 10.1111/j.1468-3083.2012.04542. (Impact Factor 2013: 2.694 / 5-year Impact Factor: 2.959)

 

Beermann S, Glage S, Jonigk D, Seifert R, Neumann D. Opposite effects of mepyramine on JNJ 7777120-induced amelioration of experimentally induced asthma in mice in sensitization and provocation. PLoS ONE. 2012; 7(1): e30285. doi: 10.1371/journal.pone.0030285. (Impact Factor 2013: 3.73 / 5-year Impact Factor: 4.244)

 

Nickel N*, Jonigk D*, Kempf T, Bockmeyer CL, Maegel L, Rische J, Laenger F, Lehmann U, Sauer C, Greer M, Welte T, Hoeper MM, Golpon HA. GDF-15 is abundantly expressed in plexiform lesions in patients with pulmonary arterial hypertension and affects proliferation and apoptosis of pulmonary endothelial cells. Respir Res 2011; 12:62. doi: 10.1186/1465-9921-12-62. (Impact Factor 2013: 3.642 / 5-year Impact Factor: 3.574)

* shared first author

 

Jonigk D*, Golpon H*, Bockmeyer CL, Maegel L, Hoeper MM, Gottlieb J, Nickel N, Hussein K, Maus U, Lehmann U, Janciauskiene S, Welte T, Haverich A, Rische J, Kreipe H, Laenger F. Plexiform lesions in pulmonary arterial hypertension composition, architecture, and microenvironment. Am J Pathol 2011 179(1): 167-79. doi: 10.1016/j.ajpath.2011.03.040. (Impact 2013: 4.522 / 5-year Impact Factor: 5.327)

* shared first author

 

Jonigk D, Merk M, Hussein K, Maegel L, Theophile K, Muth M, Lehmann U, Bockmeyer CL, Mengel M, Gottlieb J, Welte T, Haverich A, Golpon H, Kreipe H, Laenger F. Obliterative airway remodeling: molecular evidence for shared pathways in transplanted and native lungs. Am J Pathol 2011; 179(1): 167-79. doi: 10.1016/j.ajpath.2011.03.040. (Impact Factor 2013: 4.522 / 5-year Impact Factor: 5.327)

 

Al-Omari M, Korenbaum E, Ballmaier M, Lehmann U, Jonigk D, Manstein DJ, Welte T, Mahadeva R, Janciauskiene S. Acute-phase protein alpha1-antitrypsin inhibits neutrophil calpain I and induces random migration. Mol Med 2011 17(9-10): 865-74. doi: 10.2119/molmed.2011.00089 (Impact Factor 2013: 4.469 / 5-year Impact Factor: 4.993)

 

Traeder J, Jonigk D, Feist H, Brocker V, Laenger F, Kreipe H, Hussein K. Pathological characteristics of a series of rare chronic histiocytic intervillositis of the placenta. Placenta 2010; 31(12): 1116-9. doi: 10.1016/j.placenta.2010.09.012. (Impact Factor 2013: 3.117 / 5-year Impact Factor: 3.179)

 

Kumpers P, Nickel N, Lukasz A, Golpon H, Westerkamp V, Olsson KM, Jonigk D, Maegel L, Bockmeyer CL, David S, Hoeper MM. Circulating angiopoietins in idiopathic pulmonary arterial hypertension. Eur Heart J 2010; 31(18): 2291-300. doi: 10.1093/eurheartj/ehq226. (Impact Factor 2013: 14.097 / 5-year Impact Factor: 11.991)

 

Jonigk D, Theophile K, Hussein K, Bock O, Lehmann U, Bockmeyer CL, Gottlieb J, Fischer S, Simon A, Welte T, Maegel L, Kreipe H, Laenger F. Obliterative airway remodelling in transplanted and non-transplanted lungs. Virchows Arch 2010; 457(3): 369-80. doi: 10.1007/s00428-010-0949-x. (Impact Factor 2013: 2.676 / 5-year Impact Factor: 2.655)

 

Kocks JR, Adler H, Danzer H, Hoffmann K, Jonigk D, Lehmann U, Forster R. Chemokine receptor CCR7 contributes to a rapid and efficient clearance of lytic murine gamma-herpes virus 68 from the lung, whereas bronchus-associated lymphoid tissue harbors virus during latency. J Immunol 2009; 182(11): 6861-9. doi: 10.4049/jimmunol.0801826. (Impact Factor 2013: 5.52 / 5-year Impact Factor: 5.673)

 

Hussein K, Bock O, Theophile K, Schulz-Bischof K, Porwit A, Schlue J, Jonigk D, Kreipe H. MPLW515L mutation in acute megakaryoblastic leukaemia. Leukemia 2009; 23(5): 852-5. doi: 10.1038/leu.2008.371. (Impact Factor 2013: 10.164 / 5-year Impact Factor: 8.692)

 

Theophile K, Jonigk D, Kreipe H, Bock O. Amplification of mRNA from laser-microdissected single or clustered cells in formalin-fixed and paraffin-embedded tissues for application in quantitative real-time PCR. Diagn Mol Pathol 2008; 17(2): 101-6. doi: 10.1097/PDM.0b013e318163f26e. (Impact Factor 2013: 1.861 / 5-year Impact Factor: 1.818)

 

Stuht S, Gwinner W, Franz I, Schwarz A, Jonigk D, Kreipe H, Kerjaschki D, Haller H, Mengel M. Lymphatic neoangiogenesis in human renal allografts: results from sequential protocol biopsies. Am J Transplant 2007; 7(2): 377-84. doi: 10.1111/j.1600-6143.2006.01638.x. (Impact Factor 2013: 6.192 / 5-year Impact Factor: 6.014)

 

Jonigk D, Lehmann U, Stuht S, Wilhelmi M, Haverich A, Kreipe H, Mengel M. Recipient-derived neoangiogenesis of arterioles and lymphatics in quilty lesions of cardiac allografts. Transplantation 2007; 84(10): 1335-42. doi: 10.1097/01.tp.0000287458.72440.75. (Impact Factor 2013: 3.781 / 5-year Impact Factor: 3.548)

 

Mengel M, Jonigk D, Wilkens L, Radermacher J, von Wasielewski R, Lehmann U, Haller H, Mihatsch M, Kreipe H. Chimerism of metanephric adenoma but not of carcinoma in kidney transplants. Am J Pathol 2004; 165(6): 2079-85. doi: 10.1016/S0002-9440(10)63258-0. (Impact Factor 2013: 4.522 / 5-year Impact Factor: 5.327)

 

Mengel M, Jonigk D, Marwedel M, Kleeberger W, Bredt M, Bock O, Lehmann U, Gwinner W, Haller H, Kreipe H. Tubular chimerism occurs regularly in renal allografts and is not correlated to outcome. J Am Soc Nephrol 2004; 15(4): 978-86. doi: 10.1097/01.ASN.0000120369.92378.54. (Impact Factor 2013: 8.987 / 5-year Impact Factor: 8.477)            

 

 

 

 

 

Übersichtsartikel – peer-reviewed

 

Laenger F, Stark H, Braubach P, Ackermann A, Hussein K, Teiken K, Maegel, Kuehnel M, Jonigk D. Injury patterns in interstitial lung diseases. Pathologe 2018; 39(Suppl 2): 262-271. doi: 10.1007/s00292-018-0503-1. (Impact Factor 2013: 0.621 / 5-year Impact Factor: 0.6)

 

Wohlschlaeger J, Laenger F, Gottlieb J, Thomas Hager T, Seidel A, Jonigk D. Lungentransplantation: Histomorphologische Diagnostik und klinische Aspekte. Der Pathologe 2019; 40(3): 281-291. doi: 10.1007/s00292-019-0598-z. (Impact Factor 2013: 0.621 / 5-year Impact Factor: 0.6)

 

Olschewski A, Berghausen EM, Eichstaedt CA, Fleischmann BK, Grünig E, Grünig G, Hansmann G, Harbaum L, Hennigs JK, Jonigk D, Kübler WM, Kwapiszewska G, Pullamsetti SS, Stacher E, Weissmann N, Wenzel D, Schermuly RT. Pathobiologie, Pathologie und Genetik der pulmonalen Hypertonie: Empfehlungen der Kölner Konsensus-Konferenz 2016 [Pathobiology, pathology and genetics of pulmonary hypertension: Recommendations of the Cologne Consensus Conference 2016]. Dtsch med Wochenschr 2016; 141(S 01): S4-S9. doi: 10.1055/s-0042-114520. (Impact Factor 2015: 0.162 / 5-year Impact Factor: n.a.)

 

Kuehnel M, Maegel L, Vogel-Claussen J, Robertus JL, Jonigk D. Airway remodelling in the transplanted lung. Cell and Tissue Research. 2017; 367(3):663-675. doi: 10.1007/s00441-016-2529-0. (Impact Factor 2017: 3.043 / 5-year Impact Factor: 3.329)

 

Hussein K, Brix A, Matin E, Jonigk D. Tod am Nil. Ärzte Woche 2015 (Impact Factor 2015: n.a. / 5-year Impact Factor: n.a.)

 

Giagnorio R, Deindl P, Maiweg E, Ehrenberg K, Jonigk D, Hansmann G. Persistierende pulmonale Hypertonie des Neugeborenen und chronisch progressive pulmonale Hypertonie im ersten Lebensjahr. Kinder- und Jugendmedizin 2015; 15(05): 362-373.doi: 10.1055/s-0038-1629283. (Impact Factor 2015: n.a. / 5-year Impact Factor: n.a.)

 

Jonigk D. Aberrierender reparativer Gewebeumbau: Histopathologie und Molekularpathologie [Aberrant reparative tissue remodeling: Histopathology and molecular pathology]. Pathologe 2014; 35 Suppl 2: 254-63. doi: 10.1007/s00292-014-1955-6. (Impact Factor 2013: 0.621 / 5-year Impact Factor: 0.6)

 

Hussein K, Brix A, Matin E, Jonigk D. Tutanchamun: Evidenzbasierte Paleopathologie versus "Fluch des Pharao". Pathologe 2014; 36(2): 186-92. doi: 10.1007/s00292-014-1940-0. (Impact Factor 2014: 0.406 / 5-year Impact Factor: 0.6)

 

Jonigk D, Hoeper MM, Kreipe H, Laenger F. Histopathological aspects of pulmonary hypertension. Pathologe 2012; 33(3): 183-91. doi: 10.1007/s00292-011-1560-x. (Impact Factor 2013: 0.621 / 5-year Impact Factor: 0.6)

 

Wohlschlager J, Sommerwerck U, Jonigk D, Rische J, Baba HA, Mueller KM. Lung transplantation and rejection. Basic principles, clinical aspects and histomorphology. Pathologe 2011; 32(2): 104-12. doi: 10.1007/s00292-010-1403-1. (Impact Factor 2011: 0.669 / 5-year Impact Factor: n.a.)

 

Janciauskiene S, Ferrarotti I, Laenger F, Jonigk D, Luisetti M. Clinical utility gene card for: alpha-1-antitrypsin deficiency. Eur J Hum Genet 2011; 19(5). doi: 10.1038/ejhg.2010.246. (Impact Factor 2013: 4.319 / 5-year Impact Factor: 3.923)

 

Soudah B, Schirakowski A, Jonigk D. Zytologie der Lunge und Differentialdiagnose der Lungentumoren. Lungentumoren Cyto-Info 2011; 30(3): 75-81 (Impact Factor 2015: n.a. / 5-year Impact Factor: n.a.)

 

 

Buchkapitel – peer-reviewed und PubMed gelistet

 

1.            Bockmeyer CL, Jonigk D, Kreipe H, Lehmann U. MicroRNA profiling using RNA from microdissected immunostained tissue. Methods Mol Biol 2011

 

2.            Jonigk D, Modde F, Bockmeyer CL, Becker JU, Lehmann U. Optimized RNA extraction from non-deparaffinized, laser-microdissected material. Methods Mol Biol 2011

 

Wissenschaftliche Präsentationen

 

Jonigk D, Stark H, Neubert L, Schubert S, Borchert P, Linz F, Wagner WL, Stiller W, Wielpütz M, Hoefer A, Haverich A, Mentzer SJ, Shah HR, Welte T, Kuehnel M, Ackermann M. Morphomolecular motifs of pulmonary neoangiogenesis in interstitial lung diseases. ATS 2020, Philadelphia.

 

Kuehnel M, Plucinsky E, Stark H, Haverich A, Shah HR, Welte T, Jonigk D. Pollution particle analysis from idiopathic pulmonary fibrosis lungs and their effect on macrophages. ATS 2020, Philadelphia.

 

Engel B, Höfer A, Jonigk D, Hartleben B, Manns MP, Jäckel E, Taubert R. Antibodies against huntingtin interacting protein 1-related protein are more prevalent in patients with antibody mediated rejection after liver transplantation. EASL-ILC 2020, London.

 

Derben FC, Engel B, Hartl J, Jonigk D, Geffers R, Lohse AW, Manns MP, Schramm C, Jaeckel E, Taubert R. Distinct intrahepatic molecular signature between relapse and sustained remission of autoimmune hepatitis before initiation of immunosuppression withdrawal. EASL-ILC 2020, London.

 

Höfer A, Werlein C, Volk V, Feuerhake F, Kühnel M, Jonigk D. Multiplex Immunohistochemistry as a new tool to analyze cell composition of ILDs. DZL Annual Meeting 2020, Travemünde.

 

Hesse C, Wollin SL, Leeming DJ, Sand JMB, Rønnow SR, Konzok S, Niehof M, Braubach P, Jonigk D, Kühnel M, Warnecke G, Pfennig O, Fieguth H-G, Braun A, Sewald K. Nintedanib mediates effective modulation of relevant pro-fibrotic biomarkers ex vivo. DZL Annual Meeting 2020, Travemünde.

 

Beneke V, Cleeves S,  Grahl N, Danov O, Führing J, Konzok S, Braubach P, Jonigk D, Warnecke G, Zardo P, Wilkens L, Fieguth H-G, Braun A, Sewald K, Häußler S,  Wronski S. Pseudomonas aeruginosa flagellin and UGP are determinants of bacterial virulence in an ex vivo model of lung infection. DGP Herbsttagung 2019, Berlin.

 

Kreutzer FP, Meinecke A, Mitzka S, Schmidt K, Perbellini F, Beneke V, Konzok S, Hesse C, Sewald K, Jonigk D, Warnecke G, Terracciano CM, Fiedler J, Thum T.  Treatment of cardiac fibrosis with anti-proliferative small molecules. 86. Annual Meeting DGK 2020, Mannheim.

 

Theobald V, Grünig E, Benjamin N, Egenlauf B, Gall H, Halank M, Harutyunova S, Hoeper M, Jonigk D, Seyfahrt HJ, Xanthouli P, Muckenthale MU, Eichstaedt CA. Association between BMPR2 mutations and iron metabolism in pulmonary arterial hypertension patients. 86. Annual Meeting DGK 2020, Mannheim.

 

Khan P, Roux J, Savic  S, Knudsen L, Jonigk D, Kuehnel MP, Gazdhar A, Geiser T, Tamm M, Hostettler KE. Fibrosis specific KRT5+ progenitor cells in peripheral IPF lung: Characteristics and potential role. ATS conference 2020, Philadelphia.

 

Beneke V, Grahl N, Danov O, Konzok S, Braubach P, Jonigk D, Warnecke G, Pfennig O, Fieguth HG, Braun A, Sewald K, Häußler S, Wronski S. Pseudomonas aeruginosa flagellin modulates the immune response in ex vivo lung tissue slices. ERS Congress 2019, Madrid.

 

Mischak-Weissinger E, Metzger, Schleuning M, Schmid C, Messinger D, Beutel G, Wagner E, Schetelig J, Baurmann H, Rank A, Stoelzl F, Schaefer-Eckart K, Bethge W, Harsdorf S, Bunjes D, Heidenreich D, Klein S, Holler E, Kreipe H, Jonigk D, Tueruechanow I, Raad, Papkalla, Vdleyen, Iyashamwi, Ehrlich S, Krauter J, Stadler M, Ganser A. Proteomic monitoring and pre-emptive therapy of patients with acute GVHD: results from a prospective, randomized, placebo-controlled, multicentre pre-GVHD trial. COSTEM Congress 2019, Berlin.

 

Theobald V, Benjamin N, Egenlauf B, Gall H, Grünig E, Halank M, Harutyunova S, Hoeper M, Jonigk D, Seyfahrt HJ, Xanthouli P, Muckenthaler M, Eichstaedt C.A. Association between BMPR2 mutations and iron metabolism in pulmonary arterial hypertension patients. DGP Kongress 2020, Leibzig.

 

Länger F, Seidel A, Warnecke G, Gottlieb J, Werlein C, Jonigk D. Histomorphology and molecular mechanisms in acute and chronic lung allograft dysfunction. 28. Jahrestagung der Deutschen Transplantationsgesellschaft 2019, Hannover.

 

Höfer A, Taubert R, Hubscher SG, Klawonn F, Jonigk D, Manns M, Verboom M, Hartleben B, Jäckel E, Hallensleben M, Geffers R. Molecular classifier for T cell-mediated and antibody-mediated rejection after liver transplantation. 28. Jahrestagung der Deutschen Transplantationsgesellschaft 2019, Hannover.

 

Bellmas Sanz R, Falk C, Haverich A, Hitz AM, Bläsing KA,  Tudorache I, Jonigk D, Ius F, Warnecke G, Knöfel AK. Donor T and NK cells are derived from the donor lung parenchyma and represent a subset of tissue-resident memory cells. 28. Jahrestagung der Deutschen Transplantationsgesellschaft 2019, Hannover.

 

Höfer A, Verboom M, Hartleben B, Jäckel E, Hallensleben M, Geffers R, Taubert R, Hubscher SG, Klawonn F, Jonigk D, Manns M. Molecular fingerprint of T cell-mediated and antibody-mediated rejection after liver transplantation. 28. Jahrestagung der Deutschen Transplantationsgesellschaft 2019, Hannover.

 

Strauß RD, Große G, Schrimpf C, Weißenborn K, Gabriel MM, Neubert L, Kühnel MP, Jonigk D, Wilhelmi M, Falk C. Die Rolle chemotaktischer Zytokine als mögliche Biomarker zur Identifikation vulnerabler Stenosen der Arteria carotis interna. DGN 2019, Stuttgart.

 

Werlein C, Seidel A, Warnecke G, Gottlieb J, Laenger F, Jonigk D. Histomorphology and molecular mechanisms in acute and chronic lung allograft dysfunction. DTG 2019, Hannover

 

Höfer A, Jonigk D, Hartleben B, Geffers R, Klawonn F, Verboom M, Hallensleben M, S. G. Hübscher SG, Manns MP, Jäckel E, Taubert R. Molecular fingerprint of T cell-mediated

and antibody-mediated rejection after liver transplantation. DTG 2019, Hannover.

 

Pirr S, Bickes MS, Heinemann AS, Fehlhaber B, Halle S, Völlger L, Willers M, Richter M, Böhne C, Albrecht M, Langer  M, Pfeifer S,  Jonigk D, Vieten G, Ure B, von Kaisenberg C, Förster R, von Köckritz-Blickwede M, Hansen G, Viemann D. TNF-α ist essentieller Mediator der postnatalen Einwanderung von Leukozyten in Organe und Grenzflächen. DGKJ 2019, München.

 

Jonigk D. Intersitial lung-diseases – comprehensive approchaes. Böhringer Ingelheim 2019, Ingelheim am Rhein.

 

Jonigk D. Pathologie der EAA. Allergieakademie der DGAKI, Exogene allergische Alveolitis 2019, Königswinter.

 

Stauß RD, Große GM, Neubert L, Falk CS, Jonigk D, Kühnel MP, Gabriel MM, Wilhelmi M, Weissenborn K, Schrimpf C. Die Rolle chemotaktischer Zytokine als mögliche Biomarker zur Identifikation vulnerabler Stenosen der Arteria carotis interna. Deutschen Gesellschaft für Neurologie (DGN) 2019, Stuttgart.

 

Stauß RD, Große GM, Neubert L, Falk CS, Jonigk D, Kühnel MP, Gabriel MM, Wilhelmi M, Weissenborn K, Schrimpf C. Die Rolle chemotaktischer Zytokine als mögliche Biomarker zur Identifikation vulnerabler Stenosen der Arteria carotis interna. Deutschen Gesellschaft für Gefäßchirurgie (DGG) 2019, Mannheim.

 

Jonigk D. Interstitial Lung Diseases, ILD Workshop 2019, Kathmandu University.

 

Jonigk D. Diagnose Worshop ILD 2019, Braunschweig.

 

Jonigk D. Comprehensive approaches to pulmonary pathology. Translational lung research center (TLRC) 2019, Heidelberg.

 

Jonigk D. Interstitielle Lungenerkrankungen aus Sicht des Pathologen. Roche Diagnose Workshop ILD 2019, Berlin.

 

Jonigk D. Molecular background of pulmonary patterns. Boehringer Ingelheim 2019, Biberach.

 

Beneke V, Grahl N, Danov O, Konzok S, Braubach P, Jonigk D, Warnecke G, Pfennig O, Fieguth HG, Braun A, Sewald K, Häußler S, Wronski S. Pseudomonas aeruginosa flagellin modulates the immune response in ex vivo lung tissue slices. ERS 2019, Madrid.

 

Khan P, Boesch M, Fang L, Knudsen L, Savic S, Jonigk D, Kühnel M, Tamm M, Brutsche M, Baty F, Hostettler KE. IPF lung resident mesenchymal stem cells differentiate into epithelial cells displaying a disease-specific transcriptome. ERS 2019, Madrid.

 

Jonigk D. Interstitielle Lungenerkrankungen. Forum Lungenfibrose 2019, Radebeul.

 

Jonigk D. (Molecular) Diagnostic at interstitial Lung Diseases. 18th Fraunhofer Seminar "Models of Lung Disease" 2019, Hannover.

 

Obernolte H, Ritter D, Knebel J, Niehof M, Braubach P, Jonigk D, Warnecke G, Zardo P, Fieguth HG, Pfennig O, Braun A, Sewald K. Induction of pathophysiological changes in the extracellular matrix but not inflammation as early events of cigarette smoking in fresh human lung tissue. DZL Annual Meeting 2019, Mannheim.

 

Höfer A, Jonigk D, Hartleben B, Geffers R, Klawonn F, Verboom M, Hallensleben M, Hübscher SG, Manns MP, Jaeckel E, Taubert R. Molecular classifier for T cell-mediated and antibody-mediated rejection after liver transplantation. EASL/ILC2019, Vienna.

 

Sewald K, Braun A, Braubach P, Jonigk D. Integrating Human Tissue into Research and Development: Fresh Lung Tissue for Basic and Applied Research. DZL Annual Meeting 2019, Mannheim.

 

Braubach P, Neubert L, Kühnel MP, Welte T, Gottlieb J, Warnecke G, Haverich A, Jonigk D. Hannover Lung Tissue Bank – Report 2018. DZL Annual Meeting 2019, Mannheim.

 

Neubert L, Borchert P, Shin H-O, Linz F, Wagner WL, Warnecke G, Laenger F, Haverich A, Stark H, Hoeper MM, Kuehnel MP, Ackermann M, Jonigk D. Comprehensive Three-dimensional Morphology of Neoangiogenesis in Pulmonary Veno-occlusive Disease and Pulmonary Capillary Hemangiomatosis. DZL Annual Meeting 2019, Mannheim.

 

Braubach P, Märzke I, Länger F, Kühnel MP, Jonigk D. Alveolar fibroelastosis – a proposition for a comprehensive histopathological definition. DZL Annual Meeting 2019, Mannheim.

 

Danov O, Greif A, Gael M, Bailly B, Braubach P, Jonigk D, Fieguth HG, Warnecke G, von Itzstein M, Sewald K, Wronski S, Braun A. Immune response to pandemic H1N1 Influenza virus infection in human precision-cut lung slices. 29th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 2019, Amsterdam.

 

Kamp J-C, Tudorache I, Jonigk D, Länger F, Haverich A, Welte T, Prasse A, Hoeper M, Warnecke G. ISHLT Konferenz 2019, Orlando, Florida/USA.

 

Schaadt N, Jonigk D. HiLF 2018, MHH Hanover.

 

Stanke F, Tamm S, Braubach P, Schreck F, Wyrwoll M, Jonigk D, Janciauskiene S. Analysis of alpha-1-antitrypsin as a modifying agent of CFTR Expression. DZL Annual Meeting 2018, Bad Nauheim.

 

Krupar R, Watermann C, Paternack H, Ribbat-Idel J, Kuehnel M, Jonigk D. Primary and Recurrent Head and Neck Squamous Carcinomas are Strkingly Different Regarding their Immun Microenviroment. 1st Symposium on Cancer-Immuno-Oncology 2018, Lübeck.

 

Jonigk D. Translation in Transplantation. Sechenov University 260th Anniversary Celebration Moskau/Russland 2018.

 

Jonigk D. Diagnosting interstitial lung disease. German-Mazedonian tutorial on updates in pathology 2018, Skopje.

 

Höfer A, Jonigk D, Hartleben B, Verboom M, Hallensleben M, Hübscher S, Manns M, Jaeckel E, Taubert R. Donor Specific Antibodies are Associated with more Inflammation, More Fibrosis and Higher Expression of Rejection Associated Transcripts in Subclinically Rejected Liver Allografts. TTS 2018, Madrid 2018.

 

Höfer A, Hartleben B, Jonigk D, Schlue J, Verboom M, Hallensleben M, Hübscher S, Manns M, Jaeckel E, Taubert R. Prospective Evaluation of Noninvasive Cell Death Marker and Donor Specific Antibodies as Predictors of Subclinical Graft Inflammation and Graft Fibrosis. Transplantation. TTS 2018, Madrid

 

Jonigk D. Histopathologische Aspekte interstitieller Lungenerkrankungen. DZL Expertenforum Lungenfibrose, Hannover 2018.

 

Jonigk D. Interstitielle Lungenerkrankungen aus Sicht der Pathologie.Roche Diagnoseworkshop interstitielle Lungenerkrankungen 2018, Berlin.

 

Borchert P, Mägel L, Stark H, Köper M, Hussein K, Kühnel M, Jonigk D. Pulmonary veno-occlusive disease: Reevaluation von 68 Fällen. DGP 2018.

 

Jonigk D. Interstitial lung diseases. DGP 2018.

 

Hesse C, Mang S, Wollin L, Niehof M, Braubach P, Jonigk D, Kühnel M, Warnecke G, Pfennig O, Fieguth H-G, Braun A, Sewald K. Unravelling specific mechanisms of wound healing and pulmonary fibrosis in human ex vivo lung tissue slices. ERS 2018.

 

Legchenko E, Chouvarine P, Borchert P, Fernandez-Gonzalez A, Snay E, Meier M, Maegel L, Mitsialis S.A, Rog-Zielinska E, Kourembanas S, Jonigk D, Hansmann G. The PPAR? Agonist Pioglitazone Reverses Pulmonary Arterial Hypertension (PAH) and Prevents Right Heart Failure through Fatty Acid Oxidation (FAO). 2018.

 

Twisterling E S, Dahlmann F, Dehmel S, Wronski S, Braubach P, Jonigk D, Warnecke G, Krüger M, Zardo P, Sewald K, Braun A. Comparison of IP-10 production induced by ex-vivo stimulation with Respiratory Syncytial Virus (RSV) and the TLR3 agonist Poly I:C in human and non-human primate lung tissues. EAACI Congress 2018.

 

Obernolte H, Braubach P, Jonigk D, Beinke S, Belyaev N N, Lennon M, Warnecke G, Fieguth H, Hessel E M, Braun A, Sewald K, Wronski S. Transcriptomic analyses reveal anti-viral responses of epithelial cells and multiple immune cell types in HRV infected human lung tissue. EAACI Congress 2018.

 

Hesse C, Mang S, Niehof M, Braubach P, Jonigk D, Warnecke G, Pfennig O, Fieguth HG, Braun A, Sewald K. Specific induction of pro-fibrotic biomarker in human ex vivo lung tissue slices. DZL annual meeting 2018.

 

Hesse C, Mang S, Wollin L, Hoymann HG, Niehof M, Braubach P, Jonigk D, Kühnel MP, Warnecke G, Pfennig O, Fieguth HG, Braun A, Sewald K. Pirfenidone attenuates pro-fibrotic biomarker in ex vivo lung tissue slices. ATS meeting 2018.

 

Albrecht M, Oluwaseun DI, Pallenberg S, Camargo-Neumann J, Witt M, Jonigk D, Braubauch P, Warnecke G, Hansen G, Dittrich AM. IL-17A producing lymphocytes in end stage lung disease. DZL Jahresmeeting 2018.

 

Diestelhorst J, Junge N, Jonigk D, Schlue J, Falk CS, Manns MP, Baumann U, Jaeckel E, Taubert R. Baseline IgG, AIH score and IL2 can predict subsequent biochemical remission in paediatric autoimmune hepatitis. 2017.

 

Wrede C, Knudsen L, Schneider JP, Faßbender S, Jonigk D, Mühlfeld C, Ochs M, Hegermann J. Volume Electron Microscopy of Human Lung Tissue. DZL 2017.

 

Teiken K, Kühnel M, Mägel L, Braubach P, Welte T, Gottlieb J, Warnecke G, Haverich A, Kreipe H, Jonigk D. Inflammation and fibrogenesis in early lesions of chronic lung allograft dysfunction. SFB International Symposium: Cellular and Molecular Mechanisms and New Therapeutic Concepts in Transplantation 2017.

 

Jonigk D (Invited Speaker). Morphological and molecular injury patterns of the transplanted lung. International Symposium: Cellular and Molecular Mechanisms and New Therapeutic Concepts in Transplantation. SFB International Symposium: Cellular and Molecular Mechanisms and New Therapeutic Concepts in Transplantation 2017.

 

Mikosz A, Strange C, Janciauskiene S, Stolk J, Braubach P, Jonigk D, Sandhaus R, Petrache I, Serban KA. Lectin complement pathway activation in COPD and alpha-1 antitrypsin (A1AT) deficiency. Abstract ATS 2018.

 

Jonigk D. Interstitial lung disease: The view of the pathologist. Roche Workshop: idiopathic pulmonary fibrosis. Berlin 2017.

 

Weissinger EM, Metzger J, Schleuning M, Schmid C, Messinger D, Beutel G, Wagner E, Schetelig J, Baurmann H, Rank A, Stölzl F, Schäfer-Eckhard K, Westphal K, Bethge W, Bunjes D, Heidenreich D, Klein S, Wolf D, Holler E, Kreipe H, Jonigk D, Türüchanow I, Rothmann C, Raad J, Durban A, Hamwi I, Erhlich S, Schweier P, Ihlenburg-Scharz D, Krauter J, Stadler M, Ganser A. Multicentre, double-blind, placebo-controlled clinical trial (Pre-GvHD) for prediction and pre-emptive treatment of acute GvHD. ASH 2017, Atlanta.

 

Lam J, Neehus A, Haake K, Merkert S, Mucci A, Ackermann M, Schubert M, Happle C, Kühnel MP, Goethe R, Jonigk D, Martin U, Baumann U, Schambach A, Roesler J, Lachmann N. Impaired IFNγ-Signaling and Mycobacterial Clearance in IFNγR1 Deficient Human iPSC-Derived Macrophages. European Students' Conference 2017.

 

Obernolte H, Ritter D, Knebel J, Braubach P, Jonigk D, Warnecke G, Zardo P, Fieguth H, Pfennig O, Braun A, Sewald K. Cigarette smoke induces biomarkers of COPD in fresh human lung tissue. 10th World Congress “Alternatives and Animal use in the Life Sciences” 2017.

 

Hesse C, Mang S, Hoymann HG, Niehof M, Braubach P, Jonigk D, Kühnel M, Warnecke G, Pfennig O, Fieguth HG, Braun A, Sewald K. Description of a pro-fibrotic biomarker pattern in ex vivo lung tissue slices with high clinical relevance. 10th World Congress “Alternatives and Animal Use In the Life Sciences” 2017.

 

Mitschke K, Mägel L, Müller Brechlin A, Engelhardt R, Izykowski N, Kühnel M, Kreipe H, Länger F, Hussein K, Jonigk D. NanoString nCounter™ gene expression analysis of tumour stem cell factors in EBV+ post-transplant smooth muscle tumours (PTSMT) and EBV angioleiomyomas show similar expression profiles. DGP 2017.

 

Obernolte H, Braubach P, Jonigk D, Beinke S, Belyaev NN, Lennon M, Fieguth H, Hessel EM, Braun A, Sewald K, Wronski S. Transcriptomic analyses reveal anti-viral responses of epithelial cells and multiple immune cell types in HRV infected human lung tissue. ERS 2017.

 

Braubach P, Rath B, Izykowski N, Länger F, Kühnel M, Jonigk D. Systematic evaluation of reference genes for non-neoplastic pulmonary diseases with RT-qPCR and nCounter technology. DGP 2017.

 

Jonigk D, Mägel L, Mitschke K, Braubach B, Golpon H, Welte T, Janciauskiene S, Gottlieb J, Eder M, Stadler M, Warnecke G, Haverich A, Kreipe H, Kühnel M, Länger F. Similar molecular subtypes of lung injury patterns in interstitial lung disease, stem cell and lung transplantation. 58. Kongress der Deutschen Gesellschaft für Pneumologie und Beatmungsmedizin e.V. 2017.

 

Hesse C, Mang S, Hoymann HG, Niehof M, Braubach P, Jonigk D, Kühnel M, Warnecke G, Pfennig O, Fieguth HG, Braun A, Sewald K. Description of a pro-fibrotic biomarker pattern in precision-cut lung slices (PCLS). JRS 2017.

 

Hesse C, Mang S, Hoymann HG, Niehof M, Braubach P, Jonigk D, Kühnel M, Warnecke G, Pfennig O, Fieguth HG, Braun A, Sewald K. Description of a pro-fibrotic biomarker pattern in precision-cut lung slices (PCLS). DZL Jahrestreffen 2017, Munich.

 

Höfer A, Verboom M, Hallensleben M, Hartleben B, Jonigk D, Schlue J, Lehner F, Hübscher S, Manns MP, Jaeckel E, Taubert R. Donor specific antibodies are associated with higher inflammatory activity, more fibrosis and higher expression of rejection associated transcripts in human liver allografts with subclinical rejection. International Liver Congress 2017, Amsterdam.

 

Höfer A, Verboom M, Hallensleben M, Hartleben B, Jonigk D, Schlue J, Lehner F, Hübscher S, Manns M, Jaeckel E, Taubert R. Donor specific antibodies are associated with higher inflammatory activity, more fibrosis and higher expression of rejection associated transcripts in subclinical rejected human liver allografts. Abstracts of the 26th Annual Meeting of the German Transplantation Society 2017.

 

Hesse C, Mang S, Hoymann HG, Niehof M, Braubach P, Jonigk D, Kühnel M, Warnecke G, Pfennig O, Fieguth HG, Braun A, Sewald K. Identification of pro-fibrotic biomarkers in precision-cut lung slices (PCLS). ATS 2017, Washington, DC.

 

Jonigk D, Rath B, Borchert P, Braubach P, Maegel L, Izykowski N, Warnecke G, Sommer W, Kreipe H, Blach R, Anklamm A, Haverich A, Eder M, Stadler M, Welte T, Gottlieb J, Kuehnel M, Laenger F. Alveolar fibroelastosis and bronchiolitis obliterans after lung and stem cell transplantation: comparative analysis of morphological and molecular motifs. ATS 2017, Washington, DC.

 

Maegel L, Kuehnel M, Ludewig B, Borchert P, Rafikova O, Janciausciene S, Warnecke G, Hoeper MM, Black SM, Jonigk D. Histomorphological and molecular characterization of human and Sugen 5416/hypoxia induced plexiform vasculopathy. ATS 2017, Washington, DC.

 

Jonigk D. Translational reasearch in lung diseases. DGP-Nachwuchsakademie 2016, Geisenheim (Rheingau).

 

Jonigk D. Lungenfibrose aus Sicht der Pathologie. 2. DZL Expertenforum Lungenfibrose 2016, Hanover.

 

Hesse C, Mang S, Hoymann HG, Niehof M, Braubach P, Jonigk D, Warnecke G, Pfennig O, Fieguth HG, Braun A, Sewald K. Identification of pro-fibrotic biomarkers in precision-cut lung slices (PCLS).EUSAAT 2016, Linz.

 

Besa V, Hager T, Länger F, Ennekes V, Jonigk D, Theegarten D. Classification of rejection in lung transplantation: Experience of second opinion evaluation. Deutsche Transplantationsgesellschaft 2016, Essen.

 

Jonigk D. Dissecting the pulmonary vasculature in PAH. Pulmonary Hypertension Symposium - Update 2016, Hanover.

 

Weissinger E, Metzger J, Schleuning M, Schmid C, Beutel G, Rank A, Wager E, Schetelig J, Stöltzl F, Schäfer-Eckhard K, Bethge W, Bunjes D, Heindenreich D, Holler E, Niederwieser D, Kreipe H, Westphal K, Wolff D, Rothmann C, Schweier P, Tueruechanow I, Ihlenburg-Schwarz D, Durban A, Raad J, Dakna M, Jonigk D, Hamwi I, Hambach L, Krauter J, Stadler M, Ganser A. First Analysis of the multicentre, blinded, Placebo-controlled PRE-GvHD crinical-trial for prediction and pre-emptive treatment of acute GvHD in 210 of 260 patients. EHA 2016, Copenhagen.

 

Hesse C, Mang S, Hoymann HG, Niehof M, Braubach P, Jonigk D, Warnecke G, Pfennig O, Hieguth HG, Braun A, Sewald K. Induction of pro-fibrotic biomarkers in precision-cut lung slices (PCLS). ERS 2016, London.

 

Obernolte H, Braubach P, Jonigk D, Fieguth HG, Braun A, Wronski S, Sewald K. Rhinovirus infection in human lung slices is reduced by Rupintrivir. ERS 2016, London.

 

Wichmann J, Jiménez-Delgado S, Curths C, Schmitt A, Dunker S, Jonigk D, Braubach P, Kaup F-J, Braun A, Dahlmann F, Eggel A, Sewald K, Knauf S. Non-human primate and human precision-cut lung slices: a model to study efficacy of a novel disruptive IgE inhibitor. WIRM 2016, Davos.

 

Wichmann J, Jiménez-Delgado S, Curths C, Schmitt A, Dunker S, Jonigk D, Braubach P, Kaup F-J, Braun A, Eggel A, Sewald K , Dahlmann F, Knauf S. Efficacy assessment of a novel disruptive IgE inhibitor in non-human primate and human precision-cut lung slices. ATS 2016, San Francisco.

 

Weissinger EM, Metzger J, Schleuning M, Schmid C, Rank A, Beutel G, Wagner E, Schetelig J, Stölzl F, Schäfer-Eckhard K, Westphal K, Bethge W, Bunjes D, Wolf D, Holler E, Niederwieser D, Kreipe H, Jonigk D, Hamwi I, Hambach L, Schweier P, Türüchanow I, Rothmann C, Ihlenburg-Scharz D, Papkalla A, Raad J, Durban A, Dakna M, Krauter J, Stadler M, Ganser A. Urine proteomics (aGvHD_MS17) predicts acute GvHD and non-relapse mortality (interim-analyses of Pre-GvHD-trial. 42nd Annual Meeting of the European Society for Blood and Marrow Transplantation 2016, Valencia (Spain).

 

Jonigk D, Rath B, Maegel L, Golpon H, Izykowski N, Welte T, Janciauskiene S, Gottlieb J, Warnecke G, Haverich A, Kreipe H, Kuehnel M, Laenger F. Remodelling-related molecular profiles in different subforms of chronic lung allograft dysfunction. DZL Annual Meeting 2016, Hanover.

 

Wichmann J, Jiménez-Delgado S, Curths C, Schmitt A, Dunker S, Jonigk D, Braubach P, Kaup F-J, Braun A, Dahlmann F, Eggel A, Sewald K, Knauf S. A novel disruptive IgE inhibitor: Efficacy assessment in non-human primate and human precision-cut lung slices. DZL Annual Meeting 2016, Hanover.

 

Konzok S, Jonigk D, Peter D, Braubach P, Pfennig O, Fieguth H-G, Braun A, Sewald K. Bacterial and viral PAMPs and cellular DAMPs lead to activation of the inflammasome in human lung tissue ex-vivo. DZL Annual Meeting 2016, Hanover.

 

Braubach P, Lippmann T, Kuehnel M, Häußler S, Maus U, Ding N, Lehmann U, Länger F, Kreipe H, Jonigk D. In situ molecular diagnostics of infectious diseases. DZL Annual Meeting 2016, Hanover.

 

Obernolte H, Braubach P, Jonigk D, Fieguth H-G, Müller M, Braun A, Sewald K, Wronski S. Rhinovirus infection in human Precision-Cut Lung Slices is reduced by therapeutic intervention. DZL Annual Meeting 2016, Hanover.

 

Braubach P , Schaadt N, Lippmann T, Kuehnel M, Jonigk D. Characterization of Pseudomonas aeruginosa biofilm morphology and host inflammation in explanted cystic fibrosis lungs. DZL Annual Meeting 2016, Hanover.

 

Braubach P, Lippmann T, Kuehnel M, Anagnostopoulos I, Kreipe HH, Jonigk D. Fluorescence in-situ hybridization as an aid in the diagnosis of Whipple’s disease. DGP 2016, Berlin.

 

Maegel L, Ludewig B, Borchert P, Rafikova O, Kellner M, Kuehnel M, Jonigk D. Histomorphological and molecular characterization of human plexiform vasculopathy and its Sugen (SU 5416)/hypoxia induced rat model. DGP 2016, Berlin.

 

Jonigk D, Rath B, Maegel L, Golpon H, Izykowski N, Welte T, Janciauskiene S, Gottlieb J, Warnecke G, Haverich A, Kreipe H, Kuehnel M, Laenger F. Remodelling-related molecular profiles in different subforms of chronic lung allograft dysfunction. ATS 2016, San Francisco.

 

Kuehnel M, Wehling J, Kellner M, Warnecke G, Heidrich M, Izykowski N, Grothausmann R, Knudsen L, Welte T, Haverich A, Laenger F, Kreipe H, Jonigk D. 3D MORPHOLOGY MEETS MOLECULAR PATHOLOGY: Chronic Lung Alveolar Dysfunction revisited. ATS 2016, San Francisco.

 

Laenger F, Izykowski N, Rische J, Braubach P, Gottlieb J, Welte T, Haverich A, Warnecke G, Kreipe H, Kuehnel M, Jonigk D. Prospective Molecular Profiling in Human Lung Allografts. ATS 2016, San Francisco.

 

Konzok S, Jonigk D, Peter D, Braubach P, Braun A, Sewald K. Different pathways of inflammasome activation in human Precision-Cut Lung Slices (PCLS). ATS 2016, San Francisco.

 

Wichmann J, Jiménez-Delgado S, Curths C, Schmitt A, Dunker S, Jonigk D, Braubach P, Kaup F-J, Braun A, Eggel A, Sewald K, Dahlmann F, Knauf S. Efficacy assessment of a novel disruptive IgE inhibitor in non-human primate and human precision-cut lung slices. ATS 2016, San Francisco.

 

Obernolte H, Ritter D, Knebel J, Braubach P, Jonigk D, Fieguth H-G, Braun A, Sewald K. Cigarette smoke and cigarette smoke condensate induce early biomarkers of inflammation and cytotoxicity in Precision-Cut Lung slices. ATS 2016, San Francisco.

 

Jonigk D. Companion diagnostics in Breastcancer covering all methods including IHC, CISH and FISH. Najaarscongres WIHC 2015, Netherlands.

 

Maegel L, Borchert P, Lippmann T, Hoeper M, Warnecke G, Schermuly R, Kreipe H, Kühnel M, Jonigk D. Three dimensional (3D) analysis of human plexiform vasculopathy in pulmonary hypertension. „MHH – 50 Jahre wissenschaftliche Exzellenz in der Medizin“ – Wissenschaftliches Symposium 2015.

 

Kühnel M, Kellner M, Wehling J, Warnecke G, Heidrich M, Izykowski N, Vogel-Claussen J, Lorbeer R, Antonopoulos G, Janciauskiene S, Grothausmann R, Knudsen L, Ripken T, Meyer H, Kreipe H, Ochs M, Jonigk D. Correlating 3D morphology with molecular pathology: fibrotic remodelling in human lung biopsies and animal models. „MHH – 50 Jahre wissenschaftliche Exzellenz in der Medizin“– Wissenschaftliches Symposium 2015.

 

Lippmann T, Braubach P, Müsken M, Häußler S, Kühnel M, Lehmann U, Länger F, Kreipe H, Jonigk D. In-situ Molecular Diagnostics of infectious diseases. „MHH – 50 Jahre wissenschaftliche Exzellenz in der Medizin“ – Wissenschaftliches Symposium 2015.

 

Mund E, Braubach P, Länger F, Lippmann T, Warnecke G, Haverich A, Vogel-Claussen J, Ruppert C, Seeger W, Welte T, Jonigk D. Workup and Biobanking of Fresh Human Lung Explants. „MHH – 50 Jahre wissenschaftliche Exzellenz in der Medizin“ – Wissenschaftliches Symposium 2015.

 

Maegel L, Lippmann T, Höper M, Warnecke G, Schermuly R, Kreipe H, Kühnel M, Jonigk D. Plexiforme Vaskulopathie bei pulmonaler Hypertonie. 99. Jahrestagung der DGP 2015, Frankfurt.

 

Lippmann T, Müsken M, Häußler S, Kühnel M, Lehmann U, Laenger F, Kreipe H, Jonigk D, Braubach P. In-situ Erreger Diagnostik. 99. Jahrestagung der DGP 2015, Frankfurt.

 

Braubach P, Lippmann T, Engelhardt R, Maus U, Ding N, Müsken M, Häußler S, Laenger F, Jonigk D. In situ diagnostic of bacterial infections. DZL Summer School 2015.

 

Mitschke K, Maegel L, Engelhardt R, Izykowski N, Kreipe H, Laenger F, Hussein K, Jonigk D. Molecularpathological Analysis of Angiogenesis in Angioleiomyomas. 99. Jahrestagung der DGP 2015, Frankfurt.

 

Weiss A, Gernert K, Schäfer S, Maegel L, Jonigk D, Ghofrani HA, Weissmann N, Grimminger F, Seeger W, Schermuly RT. MicroRNA-9 is a regulator of PDGFRβ expression in pulmonary arterial hypertension. TLRC Lung Conference-4th DZL International Symposium 2015.

 

Lippmann T, Braubach P, Laenger F, Mund E, Warnecke G, Haverich A, Vogel-Claussen J, Ruppert C, Ochs M, Seeger W, Welte T, Jonigk D. Workup and biobanking of fresh human lung explants. DZL-Jahrestreffen 2015, Hamburg.

 

Izykowski N, Kuehnel MP, Mund E, Ochs M, Gottlieb J, Warnecke G, Kreipe HH, Laenger F, Jonigk D. Three-dimensional (3D) reconstruction of human bronchiolitis obliterans lesions. DZL-Jahrestreffen 2015, Hamburg.

 

Lippmann T, Maegel L, Mund E, Hoeper MM, Ochs M, Warnecke G, Schermuly R, Jonigk D, Kuehnel MP. Three dimensional (3D) analysis of human plexiform vasculopathy in pulmonary hypertension. DZL-Jahrestreffen 2015, Hamburg.

 

Knöfel AK, Siemeni T, Frank N, Madrahimov N, Salman J, Sommer W, Jansson K, Jonigk D, Avsar M, Haverich A, Warnecke G. Lung transplant recipients with elevated peripheral blood counts of CD127 low, FoxP3+ and CTLA4+CD4+CD25 high T cells develop less severe donor specific transplant arteriosclerosis in humanized mice. DGTHG 2015, Freiburg.

 

Knöfel AK, Siemeni T, Frank N, Madrahimov N, Jonigk D, Salman J, Sommer W, Jansson K, Avsar M, Haverich A, Warnecke G. Elevated peripheral blood counts of CD127low, FoxP3+ CD4+CD25 high T cells in lung transplant recipients leads to less severe donor specifi transplant arteriosclerosis in humanized mice. ISHLT 2015, Nice.

 

Jonigk D. Luftwegsabstoßung und chronisches Transplantatversagen. Konsensustreffen Pathologie der Lungentransplantation 2014, Hanover.

 

Jonigk D. Myofibroblastäre genexpression bei fibrosierenden Lungengerüsterkrankungen.
20. Symposium zur Hochschulinternen Leistungsförderung (HiLF) 2014, Hanover.

 

Jonigk D. Interstitielle Lungenerkrankungen. Kasuistisches Forum Niedersächsischer Pathologen 2014, Hanover.

 

Jonigk D. Molekularpathologie des Mammakarzinoms. Internationale Akademie für Pathologie 2014, Bonn.

 

Wehling J, Kellner M, Izykowski N, Braubach P, Knudsen L, Haverich A, Warnecke G, Vogel-Claussen J, Ochs M, Laenger F, Kühnel M, Jonigk D. Integrative molekulare und anatomische Charakterisierung der idiopathischen Lungenfibrose. 98. Jahrestagung der Deutschen Gesellschaft für Pathologie 2014, Berlin.

 

Jonigk D. Aberrierender reparativer Gewebeumbau. 98. Jahrestagung der Deutschen Gesellschaft für Pathologie 2014, Berlin.

 

Izykowski N, Braubach P, Rische J, Rath B, Maegel L, Gottlieb J, Welte T, Haverich A, Kreipe H, Laenger F, Jonigk D. Molecular profiling in human pulmonary allografts. 98. Jahrestagung der Deutschen Gesellschaft für Pathologie 2014, Berlin.

 

Wehling J, Kellner M, Izykowski N, Braubach P, Knudsen L, Haverich A, Warnecke G, Vogel-Claussen J, Ochs M, Laenger F, Kühnel M, Jonigk D. Integrative molecular and anatomical characterization of idiopathic pulmonary fibrosis. Breath Lecture Series „Pneumology for lung researchers“ 2014, Hanover.

 

Danov O, Jimènez Delgado SM, Drake H, Seehase S, Hohlbaum AM, Bersch C, Jonigk D, Warnecke G, Braun A, Sewald K. IL-13 induced asthma model in human precision-cut lung slices. 9th World Congress on Alternatives and Animal Use in Life Sciences 2014, Prag.

 

McCormick Smith I., Sedlacek L, Jonigk D, Rickerts V. Identification of Scedosporium and other fungi in formalin fixed, paraffin embedded tissue from patients with cystic fibrosis by broadrange PCR and Fluorescence in situ hybridization (FISH). Uetrecht 2014.

 

Wiegmann B, Jonigk D, Maegel L, Braubach P, Höffler K, Bachmann S, Janke J, Haverich A. Miniaturization of the Organ Care System® into rat lungs for the establishment of ex-vivo therapy. Jahrestagung der DGTHG 2014.

 

Jansson K, Sommer W, Avsar M, Salman J, Knöfel A-K, Hewicker-Trautwein M, Jonigk D, Haverich A, Warnecke G. Pretreatment with donor alloantigen and anti-CD4-antibody 28 days befor lung transplantation leads to immunization rather than tolerance in miniature pigs. Jahrestagung der DGTHG 2014.

 

Wehling J, Braubach P, Kellner M, Izykowski N, Knudsen L, Meyer H, Haverich A, Warnecke G, Vogel-Claussen J, Ochs M, Kreipe H, Laenger F, Kuehnel M, Jonigk D. Integrative molecular and anatomical characterization of idiopathic pulmonary fibrosis. DZL-Jahrestreffen 2014, Heidelberg.

 

Izykowski N, Braubach P, Rische J, Rath B, Maegel L, Gottlieb J, Welte T, Haverich A, Kreipe H, Laenger F, Jonigk D. Prospective molecular profiling in human pulmonary allografts. DZL-Jahrestreffen 2014, Heidelberg.

 

Jansson K, Sommer W, Avsar M, Salman J, Knöfel A-K, Falk C, Hewicker-Trautwein M, Jonigk D, Haverich A, Warnecke G. Pretreatment with donor alloantigen and anti-CD4-antibody 28 days before lung transplantation leads to immunization rather than tolerance in miniature pigs. ISHLT 2014.

 

Fytili P, Krech T, Zell S, Bockmeyer CL, Jonigk D, Lehner F, Kreipe H, Manns MP, Becker JU, Wedemeyer H. miRNA based score for the correct diagnosis of rejection vs recurrent hepatitis C in liver transplanted patients. ILC 2014, London.

 

Ludewig B, Mägel L, Izykowski N, Rath B, Black S, Ratikova O, Haverich A, Golpon H, Warnecke G, Höper M, Kreipe H, Länger F, Jonigk D. Mechanisms of pulmonary arterial hypertension in humans and rats. DZL-Breath Retreat 2013.

 

Rath B, Ludewig B, Izykowski N, Braubach P, Golpon H, Welte T, Haverich A, Warnecke G, Gottlieb J, Kreipe H, Länger F, Jonigk D. Bronchiolitis obliterans after stem cell and lung transplantation. DZL-Breath Retreat 2013.

 

Izykowski N, Mägel L, Schormann E, Hussein K, Länger F, Kreipe H, Jonigk D. Expression profile of microRNA and angiogenesis-associated factors in Epstein-Barr virus-associated post-transplant smooth muscle tumours. DZL-Breath Retreat 2013.

 

Ludewig B, Izykowski N, Rath B, Black S.M, Rafikova O, Haverich A, Golpon H, Warnecke G, Hoeper M, Kreipe H, Länger F, Jonigk D. Experimental models of pulmonary arterial hypertension in humans. 97. Jahrestagung der Deutschen Gesellschaft für Pathologie 2013, Heidelberg.

 

Izykowski N, Jonigk D, Maegel L, Schormann E, Länger F, Kreipe H, Hussein K. MicroRNA expression profile in Epstein-Barr virus-associated posttransplanted smooth muscle tumours. 97. Jahrestagung der Deutschen Gesellschaft für Pathologie 2013, Heidelberg.

 

Rath B, Ludewig B, Izykowski N, Haverich A, Warnecke G, Gottlieb J, Kreipe H, Jonigk D, Länger F. Molecular characterization of bronchiolitis obliterans after stem cell transplantation as a manifestation of GvHD. 97. Jahrestagung der Deutschen Gesellschaft für Pathologie 2013, Heidelberg.

 

Jonigk D, Rische J, Izykowski N, Maegel L, Gottlieb J, Welte T, Haverich A, Kreipe H, Laenger F. Molecular profiling in human pulmonary allografts. 97. Jahrestagung der Deutschen Gesellschaft für Pathologie 2013, Heidelberg.

 

Länger F, Golpon H, Dickgreber N, Haverich A, Krüger M, Schormann E, Rath B, Jonigk D, Kreipe H, Lehmann U. Comparative analysis of detection methods of EML4-ALK translocation in NSCLC. 97. Jahrestagung der Deutschen Gesellschaft für Pathologie 2013, Heidelberg.

 

Krech T, Fytili P, Zell S, Bockmeyer C, Jonigk D, Wedemeyer HH, Kreipe H, Becker JU. Differentially expressed microRNAs as a prognostic marker of liver allograft survival in Hepatitis C patients. 97. Jahrestagung der Deutschen Gesellschaft für Pathologie 2013, Heidelberg.

 

Atanasova S, Evers A, Jonigk D, Wilker S, Fuchs-Moll G, Petri K, Zakrzewicz A, Fischer A, Obert M, Schmitz J, Hirschburger M, Padberg W, Grau V. Experimental chronic lung allograft damage. 15th International Congress of Immunology (ICI).

 

Zimpfer A, Wolff K, Jonigk D, Hildebrandt G, Zhivov A, Erbersdobler A, Guthoff RF. Aderhautmelanome nach fraktionierter CyberKnife Radiotherapie: eine prospektive klinisch-pathologische Studie. Deutschen Ophthalmologenkongress 2013.

 

Pilatz A, Altinkilic B, Schormann E, Maegel L, Izykowski N, Becker J, Weidner W, Kreipe H, Jonigk D. Molecular Profiling in Juvenile Phimosis. 64. Kongress der Deutschen Gesellschaft für Urologie 2012, Leipzig.

 

Boeer U, Luetzner S, Jonigk D, Klingenberg M, Haverich A, Wilhelmi M. Effect of CCN1 coating of decellularized equine carotid arteries on local biocompatibility and humoral immunogenicity in a heterogenous animal model. Biomed Tech 2012, Berlin.

 

Boeer U, Luetzner S, Jonigk D, Klingenberg M, Haverich A, Wilhelmi M. Effect of CCN1 coating of decellularized equine carotid arteries on local biocompatibility and humoral immunogenicity in a heterogenous animal model. 46th annual conference of the German Society for Biomedical Engineering 2012, Jena.

 

Jonigk D, Rische J, Maegel L, Golpon H, Izykowski N, Bockmeyer CL, Welte T, Janciauskiene S, Gottlieb J, Warnecke G, Haverich A, Kreipe H, Laenger F. Remodelling-related molecular profiles in interstitial pulmonary fibrosis. UGMLC / DZL Symposium 2012, Marburg.

 

Jonigk D, Rische J, Maegel L, Golpon H, Izykowski N, Bockmeyer CL, Welte T, Janciauskiene S, Gottlieb J, Warnecke G, Haverich A, Kreipe H, Laenger F. DGP Remodelling-related molecular profiles in interstitial pulmonary fibrosis. 96. Jahrestagung der Deutschen Gesellschaft für Pathologie 2012, Berlin.

 

Maegel L, Rische J, Tiede C, Salem J, Laenger F, Kreipe H, Hussein K, Jonigk D. Histomorphological and clinical characterization of Epstein-Barr-Virus-associated post-transplant smooth muscle tumours. 96. Jahrestagung der Deutschen Gesellschaft für Pathologie 2012, Berlin.

 

Jonigk D, Rische J, Maegel L, Golpon H, Izykowski N, Bockmeyer CL, Welte T, Janciauskiene S, Gottlieb J, Warnecke G, Haverich A, Kreipe H, Laenger F. Remodelling-related molecular profiles in interstitial pulmonary fibrosis. ATS International Conference 2012, San Francisco.

 

Rafikova O, Rafikova R, Aggarwal S, Jonigk D, Black SM. Ligand-independent EGFR activation in the development of pulmonary hypertension. ATS International Conference 2012, San Francisco.

 

Ueberberg B, Janze AK, Steinwede R, Maus R, Maegel L, Hoyman HG, Braun A, Laenger F, Jonigk D, Kolb M, Gauldie J, Welte T, Maus UA. Bacterial infection triggers exacerbation of established pulmonary fibrosis in mice: impact on lung protective immunity. ATS International Conference 2012, San Francisco.

 

Buechler G, Knoefel AK, Madrahimov N, Dreckmann K, Avsar M, Sommer M, Ziehme P, Jonigk D, Laenger F, Gottlieb J, Haverich A, Strueber M, Warnecke G. The induction of stable peripheral tolerance is a result of alloantigen priming and independent from pretransplant T cells in a porcine lung transplantation model. TTS 2012, Berlin.

 

Jonigk D, Rische J, Maegel L, Bockmeyer CL, Gottlieb J, Golpon H, Hoeper MM, Welte T, Haverich A, Lehmann U, Bock O, Kreipe H, Laenger F. Longitudinal molecular profiling in human pulmonary allografts. 95. Jahrestagung der Deutschen Gesellschaft für Pathologie 2011, Leipzig.

 

Bockmeyer CL, Maegel L, Rische J, Lehmann U, Nickel N, Hoeper MM, Golpon H, Kreipe H, Laenger F, Jonigk D. Expression der miRNA 143/145 und glattmuskulärer Marker in vaskulären Strukturen bei Patienten mit pulmonaler Hypertonie. 95. Jahrestagung der Deutschen Gesellschaft für Pathologie 2011, Leipzig.

 

Laenger F, Golpon H, Dickgreber N, Jonigk D, Kreipe H, Lehmann U. Heterogenität prognostischer und prädiktiver Marker im NSCLC in In-Situ-Läsionen, invasiven Karzinomen und Metastasen. 95. Jahrestagung der Deutschen Gesellschaft für Pathologie 2011, Leipzig.

 

Jonigk D, Rische J, Maegel L, Bockmeyer CL, Gottlieb J, Golpon H, Hoeper M, Welte T, Haverich A, Lehmann U, Bock O, Kreipe H, Laenger F. Longitudinal Profiling in Human Allografts. ATS International Conference 2011, Denver (USA).

 

Bockmeyer CL, Maegel L, Rische J, Lehmann U, Nickel N, Hoeper MM, Golpon H, Kreipe H, Laenger F, Jonigk, D. Expression of miR 143 / 145 and smooth muscle differentiation markers in vascular compartments of pulmonary hypertension. ATS International Conference 2011, Denver (USA).

 

Jonigk D, Bockmeyer CL, Maegel L, Nickel N, Gottlieb J, Welte T, Hoeper MM, Laenger F, Golpon H. Comparison of plexiform lesions in PAH and glomeruloid vascular structures in glioblastoma multiforme. ATS International Conference 2011, Denver (USA).

 

Nickel N, Jonigk D, Maegel L, Welte T, Hoeper MM, Laenger F, Golpon H. GDF-15 is abundantly expressed in plexiform lesions in patients with pulmonary arterial hypertension and affects proliferation and apoptosis of endothelial cells in vitro. ATS International Conference 2011, Denver (USA).

 

Knoefel AK, Madrahimov N, Dreckmann K, Avsar M, Sommer W, Jonigk D, Haverich A, Strueber M, Warnecke G. Rejection of bronchus transplants in third-party porcinized mice is regulated by allogenic CD4+ CD 25+ T cells. ISHL 31st Annual Meeting and Scientific Sessions 2011, San Diego (USA).

 

Jonigk D, Bockmeyer CL, Maegel L, Nickel N, Golpon H, Kreipe H, Laenger F. Angiogenic microenvironment / vascular remodelling in hypertensive pulmonary disease. ATS International Conference 2010, New Orleans (USA).

 

Jonigk D, Theophile K, Hussein K, Merk M, Maegel L, Lehmann U, Kreipe H, Laenger F. Aberrant Expression of TGF-β Superfamily Members in Fibrotic Airway Remodelling. ATS International Conference 2010, New Orleans (USA).

 

Laenger F, Jonigk D, Dickgreber N, Fischer S, Kreipe H, Lehmann. EGFR-Mutations in non-small cell lung cancer – prevalence, correlation with other biomarkers and intratumoral heterogeneity. 94. Jahrestagung der Deutschen Gesellschaft für Pathologie 2010, Berlin.

 

Bockmeyer CL, Jonigk D, Maegel L, Nickel N, Golpon H, Lehmann U, Kreipe H, Laenger F. MicroRNAs regulating neo-angiogenesis and vascular smooth muscle cell proliferation are differentially expressed in plexiform lesions of pulmonary arterial hypertension. 94. Jahrestagung der Deutschen Gesellschaft für Pathologie 2010, Berlin.

 

Jonigk D, Bockmeyer CL, Maegel L, Nickel N, Golpon H, Kreipe H, Laenger F. Angiogenic (micro)environment and vascular remodeling in high grade hypertensive pulmonary disease. 94. Jahrestagung der Deutschen Gesellschaft für Pathologie 2010, Berlin.

 

Schwerk N, Metzelder M, Weidemann J, Jonigk D, Hansen G, Dingemann J, Nustede R. Seltene Ursache eines persistierenden Stridors bei einem Kleinkind. 31. Jahrestagung der Gesellschaft für Pädiatrische Pneumologie 2009, Düsseldorf.

 

Jonigk D, Mark M, Theophile K, Laenger F, Hussein K, Bock O, Lehmann U, Kreipe H. Functional Compartments in diffuse fibrotic lung disease. 93. Jahrestagung der Deutschen Gesellschaft für Pathologie 2009, Freiburg.

 

Jonigk D, Theophile K, Hussein K, Lehmann U, Laenger F, Kreipe H. Recruitment and activation of (myo)fibroblasts in lung allografts undergoing chronic injury. 92. Jahrestagung der Deutschen Gesellschaft für Pathologie 2008, Berlin.

 

Jonigk D, Stuht S, Gwinner W, Franz I, Schwarz A, Kreipe H, Kerjaschki D, Hall H, Mengel M. Lymphatic Neoangiogenesis in Human Renal Allografts. 91. Jahrestagung der Deutschen Gesellschaft für Pathologie 2007, Magdeburg.

 

Jonigk D, Lehmann U, Stuht S, Wilhelmi M, Haverich A, Kreipe H, Mengel M. VEGF-alpha promotes recipient derived neoangiogenesis in inflammatory lesions in cardiac allograf. 91. Jahrestagung der Deutschen Gesellschaft für Pathologie 2007, Magdeburg.

 

Jonigk D, Lehmann U, Broecker V, Kreipe H, Mengel, M. Chimeric neoangiogenesis in recipient derived quilty lesions of the heart – Poster of Distinction. World Transplant Congress 2006, Boston.

 

Jonigk D, Mengel M, Lehmann U, Kreipe H. Quilty Lesions in Cardiac Allografts. 90. Jahrestagung der Deutschen Gesellschaft für Pathologie 2006, Berlin.