Ausgewählte Publikationen

 

2019

 

The Role of TTP Phosphorylation in the Regulation of Inflammatory Cytokine Production by MK2/3

Ronkina N, Shushakova N, Tiedje C, Yakovleva T, Tollenaere MAX, Scott A, Batth TS, Olsen JV, Helmke A, Bekker-Jensen SH, Clark AR, Kotlyarov A, Gaestel M.

J Immunol. 2019 Oct 15;203(8):2291-2300. doi: 10.4049/jimmunol.1801221.

 

Germline deletion reveals a non-essential role of the atypical MAPK6/ERK3

Natalia Ronkina, Karin Schuster-Gossler, Florian Hansmann, Heike Kunze-Schumacher, Inga Sandrock, Tatiana Yakovleva, Juri Lafera, Wolfgang Baumgärtner, Andreas Krueger, Immo Prinz, Achim Gossler, Alexey Kotlyarov, Matthias Gaestel

bioRxiv 467597; doi: doi.org/10.1101/467597

Now published in Molecular and Cellular Biology doi: 10.1128/mcb.00516-18

 

Alternative translation initiation generates a functionally distinct isoform of the stress-activated kinase MK2

Philipp Trulley, Goda Snieckute, Dorte Bekker-Jensen, Manoj B. Menon, Robert Freund, Alexey Kotlyarov, Jesper V. Olsen, Manuel D. Diaz-Munoz, Martin Turner, Simon Bekker-Jensen, Matthias Gaestel, Christopher Tiedje

bioRxiv 429696; doi: doi.org/10.1101/429696

Now published in Cell Reports doi: 10.1016/j.celrep.2019.05.024

 

2018

 

MK2-TNF-Signaling Comes Full Circle

Menon MB, Gaestel M.

Trends Biochem Sci. 43, 158-167.

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2017

 

p38 MAPK/MK2-dependent phosphorylation controls cytotoxic RIPK1 signaling in inflammation and infection

Menon MB*, Gropengießer J*, Fischer J, Novikova L, Deuretzbacher A, Lafera J, Schimmeck H, Czymmeck N, Ronkina N, Kotlyarov A, Aepfelbacher M, Gaestel M* & Ruckdeschel K* (2017)(* equal contribution)

Nat Cell Biol. 19:1248-59.

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