Triple (GGTA1, CMAH, B2M) modified pigs expressing an SLA class-Ilow phenotype - effects on immune status and susceptibility to human immune responses.
Hein R, Sake HJ, Pokoyski C, Hundrieser J, Brinkmann A, Baars W, Nowak-Imialek M, Lucas-Hahn A, Figueiredo C, Schuberth HJ, Niemann H, Petersen B, Schwinzer R.
Am J Transplant. 2019 Nov 15. doi: 10.1111/ajt.15710. [Epub ahead of print]

Viable pigs after simultaneous inactivation of porcine MHC class I and three xenoreactive antigen genes GGTA1, CMAH and B4GALNT2.
Fischer K, Rieblinger B, Hein R, Sfriso R, Zuber J, Fischer A, Klinger B, Liang W, Flisikowski K, Kurome M, Zakhartchenko V, Kessler B, Wolf E, Rieben R, Schwinzer R, Kind A, Schnieke A.
Xenotransplantation. 2019 Oct 8:e12560. doi: 10.1111/xen.12560. [Epub ahead of print]

Possible detrimental effects of beta-2-microglobulin knockout in pigs.
Sake HJ, Frenzel A, Lucas-Hahn A, Nowak-Imialek M, Hassel P, Hadeler KG, Hermann D, Becker R, Eylers H, Hein R, Baars W, Brinkmann A, Schwinzer R, Niemann H, Petersen B.
Xenotransplantation. 2019 May 22:e12525. doi: 10.1111/xen.12525. [Epub ahead of print]

Role of human and porcine MHC DRB1 alleles in determining the intensity of individual human anti-pig T-cell responses.
Hundrieser J, Hein R, Pokoyski C, Brinkmann A, Düvel H, Dinkel A, Trautewig B, Siegert JF, Römermann D, Petersen B, Schwinzer R.
Xenotransplantation. 2019 Jul;26(4):e12523. doi: 10.1111/xen.12523. Epub 2019 May 9.

Pigs expressing the human inhibitory ligand PD-L1 (CD 274) provide a new source of xenogeneic cells and tissues with low immunogenic properties.
Buermann A, Petkov S, Petersen B, Hein R, Lucas-Hahn A, Baars W, Brinkmann A, Niemann H, Schwinzer R.
Xenotransplantation. 2018 Sep;25(5):e12387. doi: 10.1111/xen.12387. Epub 2018 Feb 15.