can bind precisely to a protein called P2Y14 as so-called ligands. "We have found the P2Y14 receptor primarily in the liver stellate cells," explains the physician. P2Y14 receptor as a link between cell death [...] signalling pathway between P2Y14 ligands and receptor. An increased release of these activated sugar molecules led to the activation of stellate cells. Inactivation of the P2Y14 receptor, on the other [...] other hand, reduced fibrosis formation. "We were also able to detect the P2Y14 receptor in human hepatic stellate cells using special antibodies," says the hepatologist. The connection between cell death of
together for the research project, critically accompanies P4D and contributes the view of those affected. Huge amounts of data have to be analysed P4D not only collects, stores and evaluates huge amounts [...] Preventive Medicine to Improve Early Detection, Diagnosis, Therapy and Prevention of Depressive Disorders" (P4D), aims to develop individualised treatment approaches using biomarkers, but also magnetic resonance [...] diagnostics. While patients with depression have so far all been treated according to the same regimen, P4D aims to determine exactly which therapy is the right one for whom. Seven universities (MHH, Leibniz
visiting regulations will apply: One visitor per patient on for one hour in the period from 2 p.m. to 7 p.m. is possible. Visits must be registered at the Service Points. All visitors need a current test
following new visiting regulations will apply: - One visitor per day for one hour in the time from 2 p.m. to 6 p.m. is possible. - Visits must either be pre-registered online (see here) or at the service points
what he wants.” The first concert will take place on 2 July, 6 p.m. at the Stephansstift in Hanover, the second concert on July 3 starts at 8 p.m. in lecture hall F in the MHH.
In the study results now published, the researchers were able to prove that the portal cap protein (pORF19) also pentamerises in solution and provide insights into how pentamerisation might be triggered [...] triggered in infected cells. Furthermore, structure-based mutagenesis on the lateral contact sites of this pORF19 pentamer, resulting in a blockade of pentamerisation, revealed severely impaired production of [...] paper "Assembly of infectious Kaposi’s sarcoma-associated herpesvirus progeny requires formation of a pORF19 pentamer" can be found here .
standard surgical method for benign prostate enlargement is transurethral resection of the prostate (TUR-P). "The prostate is scraped out with the help of a wire loop and high-frequency current," explains senior [...] Department of Urology and Urological Oncology. Aquablation: New robot-assisted therapy method But TUR-P is not the best method for all patients. "There are very good alternatives. The choice of method should [...] Urological Oncology also offers all other therapies for patients with prostate problems, for example TUR-P and laser enucleation. This makes the MHH one of the few clinics in Germany that offers the entire spectrum
treat them or prevent them altogether through preventive action," emphasises Professor Dr. Michael P. Manns, President of Hannover Medical School (MHH), who co-chaired the Liver Commission. The report [...] the field of liver diseases. SERVICE: For further information , please contact Professor Dr. Michael P. Manns, manns.michael@mh-hannover.de , telephone (0511) 532-6001. The original paper “The EASL–Lancet
care systems. This is now to change. An international panel of experts led by Professor Dr. Dr. Mike P. Wattjes from the Institute for Diagnostic and Interventional Neuroradiology at the Hannover Medical [...] development of the disease. SERVICE: For further information, please contact Professor Dr. Dr. Mike P. Wattjes, wattjes.mike@mh-hannover.de, telephone (0511) 532-2061. You can find the original paper here
the gastroenterologist. New test closes diagnostic gap These so-called polyreactive immunoglobulins (pIgG) attach themselves, among other things, to a certain protein called HIP1R, which is found throughout [...] Compared to the conventional autoantibodies that have been used to date for the diagnosis of AIH, the pIgGs are much more accurate. This means that even AIH sufferers who do not form classic autoantibodies