world's most respected science journals. New mechanism of cell communication found The focus of the study is the receptor KIT. The protein is produced by various cells, including the haematopoietic stem cells [...] Marc Reboll, research associate in Molecular and Translational Cardiology and first author of the study. The KIT-positive vascular cells ensure that new heart vessels form after a heart attack. However [...] cells produce METRNL, which stimulates the KIT-positive vascular cells to form new blood vessels." Studies in the mouse model showed that without METRNL, heart repair no longer worked. In contrast, when mice
Medical School (MHH), has now found an important molecular cause for the course of the disease. The study has been published in the renowned interdisciplinary journal Proceedings of the National Academy of [...] investigate what happens when we reactivate the switch," says Dr. Niko Hensel, first author of the study. To do this, the scientists silenced the SMN gene in the nematode Caenorhabditis elegans, which is [...] However, they do not work equally well at every point of treatment and for all those affected. "Our study could help to expand the therapy options and thus achieve better results," says Professor Claus. Next
"Our study is the first to clarify whether regular endoscopic cleaning of the bile duct system actually improves or worsens the course of SSC-CIP," emphasises the physician. The aim of the study is to [...] recommendations for diagnosis and therapy. This gap is now to be closed by a multicentre clinical study led by PD Dr. Torsten Voigtländer, Senior Consultant Endoscopist at the Clinic for Gastroenterology
programmes are now available in Germany, they are only used by less than one percent of those affected. A study led by Professor Dr. Kai G. Kahl, Managing Senior Physician at the Department of Psychiatry, Social [...] School (MHH), is now seeking to clarify why this is so and how the services can be improved. The study is supported by the state of Lower Saxony and the Volkswagen Foundation with half a million euros [...] face-to-face psychotherapy." Nevertheless, the acceptance of these free offers is low, he says. The study will now show which reasons play a role in this, for example whether too few general practitioners
are included in the study About 1,000 patients will be recruited for P4D at the five participating university hospitals in Hanover, Kiel, Greifswald, Würzburg and Frankfurt. The study is characterised by [...] ilfe (German Depression Aid Foundation) and the Bavarian company BioVariance are involved in the study, which is funded by the Federal Ministry of Education and Research (BMBF) with ten million euros over [...] neurobiological level, the clinical picture "depression" conceals different diseases. The aim of the study is to identify these diseases underlying depression in a first step. In a second step, specific biomarkers
For the receptor 5-HT7R, Professor Ponimaskin has already found a high basal activity in previous studies. "This means that the receptor is permanently active, even without serotonin binding to it," explains [...] found to be a potent inverse 5-HT7R receptor agonist," notes Dr Josephine Labus, who conducted this study with Professor Ponimaskin. It is true that dead nerve cells could not be repaired. However, in the [...] effect of amisulpride in the treatment of patients with dementia," explains Professor Ponimaskin. The study is to start before the end of this year. Text: Kirsten Pötzke
an exact diagnosis. "With our study, standardised reference values are now available that can support the diagnosis of blood and immune system diseases worldwide." The study is a cooperation project between [...] new standard values that should help to reliably distinguish between sick and healthy people. The study has been published in the renowned scientific journal "Leukemia". New standard values for twelve
also no reliable animal model on which to scientifically study responses to the virus. Developing a new treatment approach "With the multicentre study, we will then be able to access data and biosamples from [...] and the Helmholtz Centre for Infection Research (HZI) in Braunschweig, the research team wants to study a large multicentre cohort of hepatitis D patients to better understand which personal characteristics
published in the scientific journal Blood Advances. Cell clones indicate response to infusion "In our study, we looked at a very specific subset of lymphocytes, namely CD8+ cytotoxic T cells," says Dr Schu [...] leukaemia is returning or not," explains Professor Könecke. These changes were already detected in the study 11 months before the clinical diagnosis of leukaemia relapse. Biomarker also helps prevent overtreatment [...] can be detected, further donor lymphocyte administration may not be necessary. "The results of the study offer a molecular biological approach that shows whether the immunological effect of the donor lymphocytes
in midwifery in excellent quality," said the Minister on site. There are currently 61 young women studying midwifery science at MHH. MHH President Professor Dr Michael Manns and Professor Dr Mechthild Groß [...] semester, there has been a dedicated SkillsLab for midwives, as it was made compulsory for midwifery studies in the Midwives Act of 2019. This means that students have access to a fully equipped delivery room [...] dual Bachelor's degree program has been available at the MHH since the winter semester 2021/22. The study program lasts three and a half years. The entry requirement for midwifery training is a twelve-year