says Professor Claus. Next, the research team therefore wants to investigate an improved therapy and search for further molecular switches. SERVICE: For further information , please contact Professor Dr [...] still unclear how exactly the loss of motor neurones occurs. An international research team led by Professor Dr. Peter Claus, molecular biologist at the Institute of Neuroanatomy and Cell Biology at the Hannover [...] switch that is important for processing certain molecular signals in the motor nerve cells," says Professor Claus. The switch is called B-Raf and is a linchpin of the disease. "As the centre of an extensive

the stem cells come from a donor person, i.e. a relative or an anonymous person. Clinic Director Professor Dr. Arnold Ganser is pleased about the record: "We were able to help many affected people, although [...] are leukaemias, i.e. blood cancers, or lymphomas, i.e. tumours in the lymphatic tissue," explains Professor Dr Matthias Eder, Vice Clinic Director. Stem cell transplantation is indicated, for example, when [...] right time. "It could be that the person in question has Corona or is in quarantine," explains Professor Eder. "Then we would have conditioned the patient or the patient and the urgently needed donor stem

outside on the weakened heart muscle. "This is a kind of gentle, permanent cardiac massage," explains Professor Dr. Arjang Ruhparwar, Director of the Clinic for Cardiac, Thoracic, Transplantation and Vascular [...] of the continuously running pumps, the pulsatility is maintained with this new device," explains Professor Arjang Ruhparwar, "moreover, it does not come into contact with the patient's blood. Patients don't [...] the new system for 45 minutes beforehand during the operation. The team from Great Britain led by Professor Stephan Schueler also came to Hanover for the first operation of this kind worldwide. In the meantime

tool in which all of this is stored and can be retrieved in a complete and structured way," says Professor Dr. Udo Bavendiek, senior physician at the Department of Cardiology and Angiology at the MHH, giving [...] want to record the risk parameters directly when patients take their medical history," explains Professor Bavendiek. Risk parameters for cardiovascular diseases include blood pressure, blood sugar, tobacco [...] easier for those treating the patient. "Less 'text work' means more time for patients," emphasizes Professor Bavendiek. However, the structured medical history also has advantages for patients. With the data

by Professor Dr Johann Bauersachs. "In heart failure, the weakened heart tries to compensate for its reduced pumping capacity by increasing muscle mass, i.e. by growing larger," explains Professor Wollert [...] the suspicion that the inflammation might also have its good side. Now, a research team led by Professor Dr. Kai Wollert, Head of Molecular and Translational Cardiology at the Department of Cardiology [...] inflammation must be considered when thinking about anti-inflammatory therapies for heart failure, Professor Wollert and his team emphasise. Moreover, the growth factor MYGDF could possibly be administered

University of Veterinary Medicine Hannover (Professor Dr Asisa Volz, Professor Dr Maren von Köckritz-Blickwede, Professor Dr Wolfgang Baumgärtner) and TWINCORE (Professor Dr Ulrich Kalinke), a joint facility [...] Amanakis, assistant physician at the Department of Cardiology and Angiology under the direction of Professor Dr Johann Bauersachs , wants to elucidate the mechanisms by which the coronavirus influences the

The Johann Georg Zimmermann Medal 2020 / 2021 will be awarded to Professor Dr. Konstanze Döhner and Professor Dr. Hartmut Döhner. Professor Konstanze Döhner has been Clinical Senior Physician and Head of [...] with regard to the reality of care for oncological patients. "Due to the special merits of Professor and Professor Döhner, we have decided this year to award the Johann Georg Zimmermann Medal jointly to two [...] Leukemias (AML) in the Department of Internal Medicine III at Ulm University Hospital since 2000. Professor Hartmut Döhner has been Medical Director of the Clinic for Internal Medicine III since 1999 and

MHH President Professor Dr. Michael P. Manns again personally presented the doctoral certificates to the doctoral candidates during a ceremony at the university. Together with Professor Dr. Frank Bengel [...] Bengel, Dean of Research at the university, Professor Dr. Siegfried Piepenbrock, Chairman of the Society of Friends of the MHH e.V., awarded the two doctoral prize winners: Christian Niehaus, MD, MHH Clinic [...] submitted his dissertation "Mucosal-associated invariant T cells in patients with liver cirrhosis" to Professor Markus Cornberg, MD, Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology

neurodegenerative diseases such as Alzheimer's and frontotemporal dementia. A research team led by Professor Dr Evgeni Ponimaskin, a scientist at the MHH Institute of Neurophysiology , has already discovered [...] are increasingly found in brain regions that are affected in dementia. For the receptor 5-HT7R, Professor Ponimaskin has already found a high basal activity in previous studies. "This means that the receptor [...] potent inverse 5-HT7R receptor agonist," notes Dr Josephine Labus, who conducted this study with Professor Ponimaskin. It is true that dead nerve cells could not be repaired. However, in the early stages

to death within a few weeks. Already last year, an international study with the participation of Professor Dr. Michael Heuser, Senior Physician at the Department of Hematology, Hemostaseology, Oncology and [...] over four years. Combination therapy to inhibit cancer development In the earlier clinical trial, Professor Heuser, who also heads the Research Strategy and Translational Research department at the CCC Hannover [...] with IDH1-mutated AML who have already received ineffective pretreatment or have relapsed," says Professor Heuser. The first phase will determine the optimal dosage of molidustat. In the second phase, the