storage. The center's own animal husbandry area is operated in close coordination with the central animal laboratory (ZTL) of the MHH and is used for temporary animal husbandry. Animals from the center are [...] tion hybrid system for integrated positron emission tomography and computer tomography in small animals. In the coupled multimodal system, PET and CT components can either be docked or operated separately

Wohlergehen – mit Schwerpunkt auf Nutztieren [What is 'good' for animals? Ethical positions on animal welfare - with a focus on farm animals] (co-authored by Marcel Mertz) Ist das Tierrecht widersprüchlich [...] ch? Kritik an der Stellung von Tieren im Recht [Is animal law contradictory? Critical perspectives on the position of animals in law] (co-authored by Andrea Nelke) Ist die Zukunft vegan? Einstellungen [...] towards animals in the light of philosophical theories of moral progress] (co-authored by Tatiana Hetzel and Marcel Mertz) Nutztiere im Kontext von One Health. Eine ethische Betrachtung [Farm animals in the

state of research, these tests cannot be performed in small animals like mice or rats. Though these animals are well suited for many other animal studies, their hearts vary immensely from the human heart [...] performed. Here you can find further information regarding the importance of animal experiments with monkeys (German only): Animal experiments with monkeys – important questions and answers Aims of the project [...] close collaboration with their scientists, veterinarians and animal caretakers and under strict obedience of legal requirements and animal welfare. Anesthetic procedures for primates established at the

integrity of research. In this context, the Working Group also addresses issues related to the ethics of animal experimentation and the ethics of translational research . Members of the working group also research [...] Recent Publications → Pre-edited version: REIGN Framework → Open Educational Resources (OER) on animal ethics Research Team

of the area is complemented by additional rooms for data processing, project meetings, storage and animal husbandry. The supply of radiopharmaceuticals for various examinations, as well as quality control [...] Protection/Medical Physics Unit . The department is operated in close coordination with the central animal laboratory of the MHH . A permanent staff (laboratory manager, technical assistants, laboratory

Leibniz University Hannover Additional Qualifications 2024 Laboratory Animal Science (requirements comply with Annex 1 of the Animal Welfare Act, 2013, and Annex V of Directive 2010/63/EU) 2012 Gene Technology [...] Culture Models : Biomimetic 3D models of neurodegenerative diseases Development of humanized and animal-free models in order to investigate new therapeutics for neurodegenerative diseases Integration of

therapeutic application of human cardiac muscle cells, small animal models are unfortunately unsuitable, since the heart rate in these animals is much higher than in humans, and transplanted human muscle [...] Center. Here you can find further information regarding the importance of animal experiments with monkeys (German only): Animal experiments with monkeys – important questions and answers Aims of the project [...] concepts, a review of the data from in vitro studies in the living organism is inevitable. Only suitable animal models allow such therapeutic applications to be optimized and risks to be minimized before the step

s are required. These methods should allow for the tracking of the cells in not only preclinical animal models but later also in patients. In the present study, the research team led by Professor Dr. Ulrich [...] this might allow for the monitoring of survival and distribution of transplanted stem cells in both animal model and patients. In fact, using modern clinical imaging methods, these modified iPS cells could

available at our center (additional techniques can be implemented by mutual agreement): Examples of small animal PET-CT examinations: Serial 3D whole-body examination of glucose metabolism in tumor-bearing mice [...] images. Validation by ex vivo autoradiography / biodistribution measurements . Examples of small animal SPECT-CT examinations: Dopamine receptor SPECT of the basal ganglia (top left), ECG-triggered contrast

prospective recipient’s own endothelial cells. The engineered tissues being produced are tested in large animal models. Vascularized Trachea Replacements At present, there is no suitable material for repairing [...] myocardial patches are being implanted into fibrotic myocardial scar tissue. Both, small and large animal models are used for testing the practicality of this alternative approach.