workgroup aims to establish and characterize primary cholangiocyte cultures from murine, porcine and human extra- and intrahepatic tissue. Furthermore, threedimensional cholangiocyte organoids are being e

Dr. med. Christian Dopfer is a specialist in pediatrics and adolescent medicine. He studied human medicine at the Eberhard-Karls-University in Tübingen. He completed further training as a specialist at

cells in neonates and further characterize this newly described innate-like T cell population in humans.

hepatic diseases and make them the target of innovative treatment strategies. To this end, we use human induced pluripotent stem cells (iPS cells) in many projects in order to have patient-specific stem [...] genome editing procedures, we are involved in interdisciplinary discourse with partners in the humanities. Research projects Induced Pluripotent Stem Cell-Derived Hepatobiliary Organoids for Studies of [...] Advena-Regnery B, Dederer HG, Enghofer F, Cantz T , Heinemann T. Framing the ethical and legal issues of human artificial gametes in research, therapy, and assisted reproduction: A German perspective (2018). Bioethics

organoid for the first time. Robert Zweigerdt, Miriana Dardano, Lika Drakhlis (from left) How do human organs develop and what happens to them when they become diseased? To answer these questions, researchers [...] therapy for regenerating damaged hearts. HEAL Project Page TACTiC Preclinical evaluation in a non-human primate model and a roadmap for clinical application The Federal Ministry of Education and Research [...] system. With the help of induced pluripotent stem cells (iPS cells) from genetically reprogrammed human tissue cells, heart muscle cells can be produced. These should form the basic building block for a

Thum (IMTTS and Fraunhofer ITEM) Project: Investigating cardiac diseases in miniaturized LMS from human cardiac samples Marco is class speaker! Katja Bezjak SLOVENIA Bezjak.Katja @ mh-hannover.de Supervisor: [...] erology/ Hepatology/ Endocrinology and Twincore) Project: Identification and characterization of human monoclonal antibodies neutralizing Hepatitis E Virus Eline Gall GERMANY Gall.Eline @ mh-hannover.de [...] ogy) Project: Defining the nutritional components and factors that exacerbate steatohepatitis in human hepatocytes with PNPLA3-148M Chiara Malinconico ITALY Malinconico.Chiara @ mh-hannover.de Supervisor:

Frontiers ► Research Gate Differential impact of substrates on myosin heavy and light chain expression in human stem cell-derived cardiomyocytes at single-cell level, Felix Osten, Alea K Bodenschatz, Karina Ivaskevica [...] abstract available., PMID: 29992791, PubMed Differences in Contractile Function of Myofibrils within Human Embryonic Stem Cell-Derived Cardiomyocytes vs. Adult Ventricular Myofibrils Are Related to Distinct [...] PMID: 29403388, PubMed Stiff matrix induces switch to pure β-cardiac myosin heavy chain expression in human ESC-derived cardiomyocytes., Weber N, Schwanke K, Greten S, Wendland M, Iorga B, Fischer M, Geers-Knörr

Biofilms and Microbiomes. 2020. Publisher's page Heparin Anticoagulant for Human Bone Marrow Does Not Influence In Vitro Performance of Human Mesenchymal Stromal Cells. Roger, Yvonne, Burmeister, Laura, Hamm, [...] Joachim; Chemnitz, Jan. PLOS ONE. 2024. Publisher's page Transient stabilization of human cardiovascular progenitor cells from human pluripotent stem cells in vitro reflects stage-specific heart development in [...] ient humans with urinary tract anomalies Christians, Anne, Weiss, Anna-Carina, Martens, Helge, Klopf, Maximilian Georg, Hennies, Imke, Haffner, Dieter, Kispert, Andreas; Weber, Ruthild G.. Human Molecular

Techniken” (Modul BCM WP 41) Lab internships and Master thesis (scheduled individually) Medicine („Human- und Zahnmedizin“): Seminars in biochemistry/molecular biology („Nukleinsäuren und Lipide“) Practical

Toxicology and Experimental Medicine ( ITEM ), Hannover Project: Air-Liquid Interface cultures of human primary distal respiratory epithelial for in vitro modelling of SARS-CoV2 infections To investigate [...] project we will first establish methods for isolating and expanding distal epithelial cells from human lung explants and differentiate these into AT1 cells in air-liquid interface cultures that can serve