through the birth. This is possible thanks to the long-standing cooperation of a multidisciplinary team and the development of care standards. Very high risks during pregnancy Pulmonary hypertension is [...] closely together," explains Professor Olsson. "We are a highly professional, extremely well-coordinated team." For example, up to 20 experts from different disciplines are involved in a birth. The technical [...] section in the 36th to 38th week of pregnancy and is meticulously discussed and planned by the entire team before the operation. However, the care of the expectant mother begins months beforehand. For the

while at the same time the age group over 60 has the highest consumption of blood products. A research team led by Professor Dr Rainer Blasczyk, head of the Institute for Transfusion Medicine and Transplant [...] in the bone marrow and develop into platelets, which are important for blood clotting. The research team produces them in cell culture from induced pluripotent stem cells (IPSC). These are genetically r [...] thus produce platelets undisturbed without the body forming antibodies against them. The research team has already proven that the approach works in the mouse model. "Just one hour after the transfusion

development of neurodegenerative diseases such as Alzheimer's and frontotemporal dementia. A research team led by Professor Dr Evgeni Ponimaskin, a scientist at the MHH Institute of Neurophysiology , has already [...] plays a crucial role in this process. Now, in collaboration with international scientists, the MHH team has investigated the effect of the antipsychotic amisulpride on the receptor. The drug, which is approved [...] agonists, to block the receptor's signal transmission. Antipsychotic as a possible therapy The research team had already patented the substance class of inverse agonists for the treatment of dementia. However

stellate cells (HSCs) are massively involved in this tissue remodelling. An international research team led by Professor Dr. Ingmar Mederacke, Managing Senior Physician at the Department of Gastroenterology [...] exactly these molecules are related to fibrosis formation," says Professor Mederacke. The research team found out that certain stored, activated sugar molecules (UDP-glucose and UDP-galactose) are released [...] P2Y14 receptor as a link between cell death and fibrosis formation In the mouse model, the research team examined the signalling pathway between P2Y14 ligands and receptor. An increased release of these

based on the individual analysis of each cell," says Professor Ravens. Using this technology, the team studied gamma-delta T cells in cord blood samples as well as from adult blood samples. "Interestingly [...] persist as innate immune cells throughout life in humans," reports Dr Fichtner. Only recently, the team was able to show that certain gamma-delta T cells proliferate expansively directly after birth and [...] Cluster of Excellence RESIST (Resolving Infection Susceptibility), led by the MHH, about 50 research teams are working towards one goal: they want to make it possible for particularly vulnerable people to

17.02.2022 Infection research is about more than just corona viruses - also in the RESIST team, a Cluster of Excellence led by Hannover Medical School (MHH). The approximately 50 scientists are looking [...] Weakest In the Cluster of Excellence RESIST (Resolving Infection Susceptibility), about 50 research teams are working on one goal: they want to better protect particularly vulnerable people from infections

Pneumology at the Hannover Medical School (MHH) has now taken a decisive step forward in this regard: The team found out that smoking probably plays a causal role in the development of a particularly severe form [...] the Department of Pneumology. Researchers compared three different patient groups In the study, the team compared three different patient groups. The first group consisted of patients with IPAH who had smoked [...] younger, responded better to drug therapies and had a significantly longer life expectancy. The study team concluded that patients with a diagnosis of IPAH and a history of smoking, as well as severely impaired

transplant. For successful treatment, the disease must be detected as early as possible. A research team led by Dr. Richard Taubert, senior physician at the Department of Gastroenterology, Hepatology and [...] another, they can also be detected in other diseases and are therefore not specific. The research team therefore set out to find precise autoantibodies that are typical for AIH and differ from the markers [...] half a day, numerous patients with liver disease could be spared a liver biopsy. The MHH research team has already been able to test the reliability of the new test on several hundred blood samples from

as informative as possible, and the radiation exposure for patients should be as low as possible. A team from the Institute of Diagnostic and Interventional Radiology at the Hannover Medical School (MHH) [...] this also means additional radiation exposure. The newly developed CT protocol of Professor Shin's team, on the other hand, provides all the information in just one step. To do this, the experts use ph [...] patients in Lower Saxony, who also benefit from the lower radiation exposure of modern CT. The research teams in radiology are working intensively to identify further potential applications, for example in cancer

Whether such cells also exist in the human lung remained controversial in science. Now, a research team led by Professor Dr. Christian Mühlfeld, acting head of the Institute of Functional and Applied Anatomy [...] humans. Final proof through a combination of different detection methods To answer that, the research team took an unusual step. "We combined the different detection methods from various research publications [...] healthy, fibrotic or damaged (emphysematous) human lung tissue provided by Professor Dr. Danny Jonigk's team from the MHH-Institute of Pathology. Dr. Julia Schipke used various markers to highlight different