Status: 11 February 2021 On average, a human being consists of about 30 trillion body cells - and just as many bacteria. Without them, we would not be able to live. Not only in the intestine, on our skin [...] the renowned journal Biofilms and Microbiomes. Microorganisms form a community "Until recently, the human lower respiratory tract was considered sterile," explains Professor Tümmler. Therefore, most studies [...] assign it correctly. "The respective secretion samples contained only a few billionths of a gram of genetic material and about 90 per cent of that came from the children and only ten per cent from the mic

clinics and institutes are also on board. These include experts from haematology, nephrology, gastroenterology, immunology, nuclear medicine, pathology, plastic surgery, paediatrics, human genetics and radiology

23.09.2022 Li-Fraumeni syndrome (LFS) is a rare genetic disorder associated with a greatly increased risk of various types of cancer. The genetic defect can lead to multiple occurrences of malignant tumors [...] LFS-CPS@mh-hannover.de or by phone at (0511) 532-9037. Whole-body MRI examinations are performed at the Institute for Diagnostic and Interventional Radiology (Director: Professor Dr. Frank Wacker), where the contact [...] Radiology. Li-Fraumeni syndrome is one of the cancer disposition syndromes and is caused by a hereditary genetic alteration in the TP53 gene. Professor Kratz has been working on Li-Fraumeni syndrome for many years

ducts and gallbladder. BCTs are rare and account for less than one percent of malignant neoplasms in humans. Overall, BCT have a poor prognosis. Five years after diagnosis, only 10 to 20 percent of those affected [...] n from the European Medicines Agency (EMA). Breakthrough in molecular sequencing The search for genetic alterations using molecular sequencing has led to significant successes in the treatment of cancer [...] for biliary tumours," Vogel points out. "Almost 40 per cent of patients with biliary tumours have genetic alterations that are potential targets for precision medicine and for which we now have targeted

German Tumour Centre, he moved in 1987 to the Institute of Genetics at the Faculty of Natural Sciences at the University of Bonn, where he habilitated in genetics and immunology in 1993. In the same year, [...] their home institutes. In 2018, Prof. Abken moved to the University of Regensburg, where he holds the Chair of Gene Immunotherapy, has played a major role in establishing the Leibniz Institute for Immunotherapy [...] associate at the LOEWE centre Frankfurt Cancer Institute. Since 2021, the 39-year-old has headed his own research group at the Pharmacological Institute of the Department of Medicine at Philipps University

spectrum in children and adolescents.” Early genetic testing is not necessary According to the paediatric oncologist, there is no need to adapt current genetic tests or surveillance practices: "In children [...] in an affected child with cancer also offers adult family members the opportunity for genetic counselling and genetic testing to clarify their own risk of developing the disease." SERVICE: For further i [...] Professor Christian Kratz, initiator of the study published in the Journal of the National Cancer Institute. "A statistically significant association with malignant diseases of the blood system, such as

computer-assisted and statistical approaches to investigate the effect of genetic factors - at a variety of molecular levels (e.g. genetics, metabolomics), immunological parameters and functions as well as infectious [...] sciences. The "Who's Who" of science also provides information about the countries and research institutions in which the scientific elite work. 336 of these experts work in Germany, putting it in fourth [...] pulmonary hypertension, i.e. pulmonary hypertension. Professor Dr Thomas Thum is Director of the MHH Institute for Molecular and Translational Therapy Strategies. For many years, the cardiologist and bioscientist

at the Institute of Transfusion Medicine and Transplant Engineering . Hereditary primary haemochromatosis is one of the most common inborn errors of metabolism in Europe. The cause is a genetic defect [...] approach, but also for translational application in other monogenetic diseases and those in which genetic effectors play a central role. The prize was awarded on 1 July during the 19th HepNet Symposium.

study in humans The combination has already been shown to work in human AML cell cultures and in mouse models. Now the efficacy, safety and tolerability of the new therapy are to be tested in a human clinical [...] cells of the hematopoietic system proliferate uncontrollably. This form of blood cancer is caused by genetic changes in the bone marrow that occur in the course of life. It is therefore mainly older people

and thus trigger leukaemia. Now, an international research team led by Dr. Michael Rothe from the Institute of Experimental Haematology at the Hannover Medical School (MHH) has developed a safety test that [...] studies, however, individual patients developed leukaemia after they had been transplanted with the genetically modified blood stem cells. "This happens when the vector inserts itself near cancer genes and activates [...] conclusive," the scientist emphasises. The IVIM (In Vitro Immortalisation) test developed at the Institute of Professor Dr Axel Schambach several years ago and approved in the USA, Canada, Australia and