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Welcome to the MHH News
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News

CT of the lungs: new method makes structure and function visible at the same time

Relevance: 89%
 

step "Computed tomography is the imaging technique of choice for analysing lung diseases," says Professor Dr Hoen-oh Shin, senior physician at the Department of Diagnostic and Interventional Radiology and [...] For patients, this also means additional radiation exposure. The newly developed CT protocol of Professor Shin's team, on the other hand, provides all the information in just one step. To do this, the experts [...] two millimetres. "The quality of the images is clearly superior to that of a standard CT," notes Professor Dr Shin. With the new imaging options, there are better diagnostic possibilities, for example in

News

Search for alternatives to animal testing in research continues to be promoted

Relevance: 89%
 

e Systems" research network led by Professor Dr. André Bleich, Director of the Institute of Laboratory Animal Science at Hannover Medical School (MHH), and Professor Dr. Maren von Köckritz-Blickwede from [...] experiments has been constant for years, while they are declining in other research areas," explains Professor Bleich. However, interdisciplinary collaboration has already enabled various alternative models [...] oxygen conditions in the intestine are different from those in the lung tissue in the breath," says Professor von Köckritz-Blickwede. "It's important that we can perform the studies under realistic conditions

News

Exploring the role of organ and immune ageing in heart and lung diseases

Relevance: 89%
 

diseases. However, little is known about the molecular biological causes. A research team led by Professor Dr. Christian Bär from the Institute of Molecular and Translational Therapy Strategies of the Hannover [...] ability to divide completely. “Telomer lengths are therefore biological markers of age,” explains Professor Bär. Chimeric mouse models with different organ and immune ages The research team will first investigate [...] but also to examine the influence of telomere shortening and telomere damage in detail,” says Professor Bär. Gene therapy could improve organ regeneration The studies are also intended to lay the foundation

News

MHH researcher wants to develop gene therapy against hearing and balance disorders

Relevance: 89%
 

children and adults from hereditary deafness with the help of gene therapy is one of the goals of Professor Dr. Dr. Axel Schambach, head of the Institute for Experimental Haematology at Hannover Medical School [...] a loss of vision and balance. Responsible for this is a mutation in a gene called MYO7A, which Professor Schambach and his team are focusing on. If a person inherits the damaged gene from both father and [...] . "Since MYO7A is a very large gene, we need a gene taxi with a large boot, so to speak," says Professor Schambach. The research team therefore uses lentiviral vectors (LV), which can carry a large amount

News

MHH fills important gap in lung research

Relevance: 89%
 

cells also exist in the human lung remained controversial in science. Now, a research team led by Professor Dr. Christian Mühlfeld, acting head of the Institute of Functional and Applied Anatomy at the Hannover [...] rats, it was found that this cell type influences several important functions in the lungs," says Professor Mühlfeld. For example, the cell plays an important role as a vitamin A store in the development [...] tissue sections from healthy, fibrotic or damaged (emphysematous) human lung tissue provided by Professor Dr. Danny Jonigk's team from the MHH-Institute of Pathology. Dr. Julia Schipke used various markers

News

Baby bliss despite severe illness

Relevance: 89%
 

are well controlled and stabilised with medication, they can live with it for a long time," says Professor Dr Karen Olsson, senior physician in the Department of Pneumology. "Many of the affected women lead [...] possible counselling and care, even if the desire to have a child is not always feasible," explains Professor Olsson. The senior physician has been working on this issue for 15 years. It started with a scientific [...] as cardiac, thoracic, transplantation and vascular surgery work very closely together," explains Professor Olsson. "We are a highly professional, extremely well-coordinated team." For example, up to 20 experts

News

NMOSD patients: Less cognitive impairment than previously assumed

Relevance: 88%
 

CogniNMO study. A total of 17 treatment centers specialised in the disease in Germany took part. Professor Dr Corinna Trebst and Dr Martin Hümmert from the Department of Neurology at the Hannover Medical [...] been clear until now. Studies had delivered different and partly contradictory results on this," Professor Trebst describes the initial situation. Cognitive abilities are various processes that serve the [...] percent in at least two cognition tests, is much lower than assumed from previous studies," explains Professor Trebst. The cognitive impairments are not related to disease relapses or to the presence of an antibody

News

Using immune cells to develop new active substances and improve the efficacy and safety of drugs

Relevance: 88%
 

cells and immune cell preparations are playing an increasingly important role in modern medicine. Professor Dr. Nico Lachmann, research group leader at the Clinic for Paediatric Pneumology, Allergology and [...] different. "This is a major problem for the health industry and massively slows down innovation," Professor Lachmann points out. In order to meet the steadily growing demand, biomedical research is therefore [...] and drugs. Based on this key technology for the continuous production of macrophages from iPSC, Professor Lachmann's team also wants to develop new manufacturing processes for different fully standardised

News

Variants in BRCA1/2 and MMR genes in children with cancer

Relevance: 88%
 

or MMR gene variants were mainly affected by brain tumours but also other solid tumours," says Professor Christian Kratz, initiator of the study published in the Journal of the National Cancer Institute [...] such a variant in a healthy child would currently not justify any immediate medical consequences," Professor Kratz emphasises. "Our results therefore give no reason to change the current practice of predictive [...] treating a child with cancer and the type of follow-up care after treatment has been completed," says Professor Kratz. "The detection of BRCA1/2 or MMR gene variants in an affected child with cancer also offers

News

Drug combination triples survival time with blood cancer

Relevance: 88%
 

diagnosed AML. This was the result of an international clinical study with the participation of Professor Dr. Michael Heuser, Senior Physician at the Department of Haematology, Haemostaseology, Oncology [...] compounds in the mouse model a few years ago and observed significant synergistic effects," says Professor Heuser. In the clinical trial, the researchers were now also able to demonstrate this effect in [...] for patients for whom intensive chemotherapy to fight the tumour is out of the question," says Professor Heuser. Another advantage is that undesirable side effects such as infections, pneumonia or blood

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The MHH Hospital is a maximum care hospital with a nationwide catchment area. The university teaches medicine, dentistry, biochemistry, biomedicine, midwifery and health sciences. The main research areas are Transplantation and Stem Cell Research / Regenerative Medicine, Infection and Immunology Research, Biomedical Engineering and Implant Research.

   

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