11.05.2023 How do human cells defend themselves against adenoviruses? The team of RESIST Professor Dr. Sabrina Schreiner from the Institute of Virology at the Hannover Medical School (MHH) has come a good [...] and Dr Christina Weiß from the Institute of Virology at the Technical University of Munich from Professor Schreiner's research group there. The team of authors also includes Dr Samuel Hofmann from the MHH [...] example. They can also die from such an infection. Cells defend themselves with the protein Apobec3A Professor Schreiner's team has now found that human cells defend themselves against adenovirus infection with

heart muscle because connective tissue cells are deposited, the so-called fibrosis. For years, Professor Dr. Dr. Thomas Thum, head of the Institute for Molecular and Translational Therapy Strategies at [...] and fill the heart chambers with enough blood. So far, this cardiac fibrosis is hardly treatable. Professor Thum and his research team are focusing on so-called long non-coding RNAs (lncRNA). These are building [...] Meg3 inhibitor in animal models for efficacy safety in order to reach clinical maturity," explains Professor Thum. For this phase of drug development, it is usually very difficult to get the necessary financial

" emphasises Professor Kratz, who, besides others, was in involved in the development of the Li-Fraumeni spectrum classification. SERVICE: For further information , please contact Professor Dr. Christian [...] for the first time using data from the German Cancer Predisposition Registry. In the study led by Professor Dr. Christian Kratz, Director of the Department of Paediatric Haematology and Oncology at Hannover [...] prediction," says Penkert from the Institute of Human Genetics, who is currently conducting research in Professor Kratz's team. A total of 141 people from 94 families with disease-causing TP53 variants were analysed

employer for the brightest minds," emphasises MHH President Professor Dr. Michael P. Manns. SERVICE: For further information, please contact Professor Dr. Dr. Anette Melk, melk.anette@mh-hannover.de or visit [...] scientific training, the content of which is precisely tailored to the individual participants," says Professor Dr. Dr. Anette Melk, spokesperson for the programme. The three-year funding period is professionally [...] career in academic medicine, but at the same time increases the quality of patient care," explains Professor Melk. The programme builds on successful career programmes for clinician scientists developed at

School (MHH) are now using a new treatment procedure for severe heart attacks. The team led by Professor Dr. Andreas Schäfer, Head of Cardiovascular Intensive Care Medicine, is using - for the first time [...] survive it develop severe heart failure due to the large scarring of the heart muscle," explains Professor Schäfer. These patients can benefit from SSO2 therapy. It is used in the event of an acute heart [...] muscles were only minor, and the pumping capacity of the heart showed no relevant limitations," says Professor Johann Bauersachs, M.D., Director of the Department of Cardiology and Angiology. SSO2 therapy improves

MHH President Professor Dr. Michael Manns is one of the best researchers in the world. This is the result of the second edition of a ranking that has just been published by the academic platform Research [...] Scientists in the World 2023" ranking includes leading scientists from all important research areas. "Professor Manns is one of the most cited researchers in Europe and worldwide and has received numerous awards [...] we have one of the most renowned physicians in Lower Saxony." Ranked 40th in Germany Apart from Professor Manns, there are only 47 other researchers in the whole of Germany who are listed internationally

outside on the weakened heart muscle. "This is a kind of gentle, permanent cardiac massage," explains Professor Dr. Arjang Ruhparwar, Director of the Clinic for Cardiac, Thoracic, Transplantation and Vascular [...] of the continuously running pumps, the pulsatility is maintained with this new device," explains Professor Arjang Ruhparwar, "moreover, it does not come into contact with the patient's blood. Patients don't [...] the new system for 45 minutes beforehand during the operation. The team from Great Britain led by Professor Stephan Schueler also came to Hanover for the first operation of this kind worldwide. In the meantime

University of Veterinary Medicine Hannover (Professor Dr Asisa Volz, Professor Dr Maren von Köckritz-Blickwede, Professor Dr Wolfgang Baumgärtner) and TWINCORE (Professor Dr Ulrich Kalinke), a joint facility [...] Amanakis, assistant physician at the Department of Cardiology and Angiology under the direction of Professor Dr Johann Bauersachs , wants to elucidate the mechanisms by which the coronavirus influences the

tool in which all of this is stored and can be retrieved in a complete and structured way," says Professor Dr. Udo Bavendiek, senior physician at the Department of Cardiology and Angiology at the MHH, giving [...] want to record the risk parameters directly when patients take their medical history," explains Professor Bavendiek. Risk parameters for cardiovascular diseases include blood pressure, blood sugar, tobacco [...] easier for those treating the patient. "Less 'text work' means more time for patients," emphasizes Professor Bavendiek. However, the structured medical history also has advantages for patients. With the data

by Professor Dr Johann Bauersachs. "In heart failure, the weakened heart tries to compensate for its reduced pumping capacity by increasing muscle mass, i.e. by growing larger," explains Professor Wollert [...] the suspicion that the inflammation might also have its good side. Now, a research team led by Professor Dr. Kai Wollert, Head of Molecular and Translational Cardiology at the Department of Cardiology [...] inflammation must be considered when thinking about anti-inflammatory therapies for heart failure, Professor Wollert and his team emphasise. Moreover, the growth factor MYGDF could possibly be administered