protein kinases mediate recruitment of CREB-binding protein to preserve fast myosin heavy chain IId/x gene activity in myotubes. J. Biol. Chem., 282, 7265-7275. da Costa, N., Edgar, J., Ooi, P.-T., Su, Y. [...] Meissner, J.D. , and Chang, K.-C., 2007. Calcineurin differentially regulates fast myosin heavy chain genes in oxidative muscle fibre type conversion. Cell Tissue Res., 329, 515-27. Hanke, N., Meissner, J.D [...] Manukjan, G., Ewers, D., Umeda, P.K., Chang, K.-C., Kubis, H.P., Gros, G., and Meissner, J.D. , 2011. Gene regulation mediating fibre-type transformation in skeletal muscle cells is partly glucose- and Ch
awarded to Prof. Dr Hinrich Abken, Director at the Leibniz Institute for Immunotherapy and Chair of Gene Immunotherapy at the University of Regensburg, for his services to the immunotherapy of oncological [...] institutes. In 2018, Prof. Abken moved to the University of Regensburg, where he holds the Chair of Gene Immunotherapy, has played a major role in establishing the Leibniz Institute for Immunotherapy (LIT)
Kotlyarov, A., and Gaestel, M. (2011). Stress induced gene expression: a direct role for MAPKAP kinases in transcriptional activation of immediate early genes. Nucleic Acids Res 39, 2503-2518. 168. Rump, A. [...] Kotlyarov, A., and Gaestel, M. (2011). Stress induced gene expression: a direct role for MAPKAP kinases in transcriptional activation of immediate early genes. Nucleic Acids Res 39, 2503-2518. 244. Rump, A. [...] Kubsch, T., Keyser, K. A., Binz, A., Bauerfeind, R., Sodeik, B., Cicin-Sain, L., et al. (2017). The M25 gene products are critical for the cytopathic effect of mouse cytomegalovirus. Sci Rep 7, 15588. 19. Luo
attributed to the activation of Siglec-16 by polysialic acid." "Remarkably, due to a naturally occurring gene mutation, only part of the population is able to produce Siglec-16, while polysialic acid could be
induces a massive reduction of the expression of CCR7 on infected dendritic cells (DC). The viral genes responsible for this process shall therefore be identified and the cellular mechanisms mediating the
research on the topic of " Gene correction of human induced pluripotent stem cells repairs the cellular phenotype in Pulmonary Alveolar Proteinosis ". They are working on a new gene therapy for the rare, [...] Dr. Gesine Hansen and Professor Dr. Thomas Moritz for the development of an innovative approach to gene therapy for pulmonary alveolar proteinosis. Christiane Herzog Center for Cystic Fibrosis opened Internists [...] Pneumology (GPP) in Graz on April 2, 2012. Sven Michel for a poster entitled "Unifying Candidate Genes and GWAS Approaches in Asthma", and Solveig Kristin Gleicher for her poster "Role of alveolar macrophages
.ppat.1008560. eCollection 2020 Jul. PMID: 32667948 Free PMC article. DNA Methylation of the t-PA Gene Differs Between Various Immune Cell Subtypes Isolated From Depressed Patients Receiving Electroconvulsive [...] Jul;36:18-28. doi: 10.1016/j.euroneuro.2020.03.019. Epub 2020 May 21. PMID: 32446707 Mutations of the gene FNIP1 associated with a syndromic autosomal recessive immunodeficiency with cardiomyopathy and pr [...] Down-regulation of the fetal stem cell factor SOX17 by H33342: a mechanism responsible for differential gene expression in breast cancer side population cells. Christgen M, Geffers R, Ballmaier M, Christgen
assessment of cells’ genetic stability. Moreover, a genetic rescue tool in the form of a biallelic suicide gene for inducing a controlled, programmed cell death will be established as another addition to the safety [...] 2: Immunogenicity of HLA homozygous iPS-cardiomyocytes WP 3: Safety, genetic integrity, and suicide gene technologies WP 4: Regulations and Advanced Therapy Medicinal Product (ATMP) development WP 5: Cost
a future key role in translational medicine. The technical focus is generally on cell-based and/or gene therapy therapies . The organ or disease system is open and can therefore include, for example, infections [...] cardiovascular-, chronic inflammatory diseases as well as congenital disorders and beyond. Cell- and gene-based therapies, ranging from the transplantation of classical hematopoietic- or mesenchymal stem
Advanced Tissue Culture Models, biomimetic 3D models of neurodegenerative diseases, CRISPR/Cas-based gene editing, 3D bioprinting +49(0)511 532 2911 Schadzek.Nadine @ mh-hannover.de Expert profile Dr. rer