Current Projects Currently, we aim to elucidate the structural determinants of the immune defense mechanisms by NODlike receptors (NLRs) in infectious processes. Moreover, we want to analyse how patho

Conference Presentations (Selection) - Dr. Manuel Taft Conference Presentations 2022 - September: Invited Talk “The role of class-18 myosins in the assembly, organization and regulation of muscle stre

Structural and Functional Analysis of Disease Relevant Proteins Copyright: Nico Herzog Fotografie PD Dr. rer. nat. Susanne Eschenburg Institute for Biophysical Chemistry, OE4350 Hannover Medical Schoo

Methods Macromolecular X-ray crystallography State-of-the-art molecular biological and cell biological techniques Heterologous protein expression in prokaryotic and eukaryotic hosts Protein purificati

Methods Our group employs a combinatory approach of biochemistry, biophysics, TIRF imaging with purified proteins, genome editing and cell biology to better understand the molecular basis of a number

Teaching Bachelor of Science Biochemistry: Molecular Biochemistry and Methods (BCB P 15) Master of Science Biochemistry: Instrumental techniques (BCM WP 41) Human Medicine and Dentistry: Biochemistry/

Current Projects Analyses of actin-binding proteins in motility, phagocytosis and regulation of the cell cortex

Alumni Graduate Students Graduate Students Dr. Steve Ludbrook (1993-1996 PhD in the Eccleston and Manstein groups) Director Molecular Pharmacology, Bicycle Therapeutics, Cambridge, England, United Kin

Methods Methods Molecular and Cell Biology: mammalian cell cultures; human oocytes; primary neuronal and glial cells; D. discoideum ; immunohictochemistry; transfection Spectroscopy: Absorption and Fl

Research Interests Actin Myosin Dynamin Tropomyosin Cell motility and cytoskeletal dynamics Intracellular pathogen sensors Protein structure, dynamics, reaction mechanisms, and allostery Small-molecul