immune system within the body are different. Biologically young animals with long telomeres receive the bone marrow of biologically old animals with shortened telomeres, so that they now have young organs
Hospital Hygiene Institute of Virology Institute of Immunology Institute for Laboratory Animal Science and Central Animal Laboratory Institute of Molecular Biology Institute for Transfusion Medicine Institute
in association with the program Practical Courses: Application of Real-time PCR Basic Laboratory Animal Science Bio Informatics CRISPR/Cas9 gene editing in primary T cells Digital Fluorescence microscopy
Miniature hearts for research Replacing animal experiments: an MHH research team has succeeded in producing a haematopoietic heart organoid for the first time. Robert Zweigerdt, Miriana Dardano, Lika Drakhlis [...] also suitable for testing pharmacological agents. ‘In some cases, this works even better than in animal models, for example, because these are subject to other biological influences and the results can
patients with CF. Complementary to standard antimicrobial chemotherapy, we are exploring options in animal models to prevent lower respiratory tract infections via local transfer of macrophages, CFTR gene [...] Pseudomonas Genomics Pseudomonas aeruginosa lives in soil, fresh and salt water and colonizes plant and animal surfaces. In humans, P. aeruginosa has become one of the most common bacterial pathogens of local
brain abnormalities in humans. We found that stress induces muscle degeneration even in wild type animals and accelerates age-dependent muscular dystrophy and that miRNAs are involved in this process. Future
students). Heads the research commission of the MHH (FoKo) Heads the MHH advisory board for the central animal facility, currently represented by Prof. Dr. Reinhold Förster. Cooperation with the Ombudsperson
successfully prove that the cell clumps actually grow in the heart tissue and improve organ function in animal models as part of the iCARE project coordinated by Professor Martin. In the new research project [...] biologist. The researchers want to investigate the possible side effect of arrhythmias in a large animal model, which reacts particularly sensitively to disturbances caused by the foreign cardiomyocytes
PhD students are fully financed for 3-4 years. Courses available outside the curriculum include: Animal Handling Gene Technology Omics and Bioinformatics Good Scientific Practise Master Class Lectures
ce in-situ hybridization (FISH) in the diagnosis of hematological diseases Animal experimental methods (introduction) Animal experimental methods (specific courses) 2.2 Special Seminars: Molecular biological [...] as ‘Presentation techniques', ‘Scientific writing', ‘Research ethics', ‘Gene technology safety', ‘Animal experiments' as well as career perspectives. Excursions to industry also take place regularly. See [...] institutes to provide up-to-date technologies and support (e. g. gene expression profiling, experimental animal work, confocal microscopy for in vivo imaging, and proteomics). A huge library with relevant textbooks