immune system within the body are different. Biologically young animals with long telomeres receive the bone marrow of biologically old animals with shortened telomeres, so that they now have young organs

brain abnormalities in humans. We found that stress induces muscle degeneration even in wild type animals and accelerates age-dependent muscular dystrophy and that miRNAs are involved in this process. Future

students). Heads the research commission of the MHH (FoKo) Heads the MHH advisory board for the central animal facility, currently represented by Prof. Dr. Reinhold Förster. Cooperation with the Ombudsperson

Hospital Hygiene Institute of Virology Institute of Immunology Institute for Laboratory Animal Science and Central Animal Laboratory Institute of Molecular Biology Institute for Transfusion Medicine Institute

Miniature hearts for research Replacing animal experiments: an MHH research team has succeeded in producing a haematopoietic heart organoid for the first time. Robert Zweigerdt, Miriana Dardano, Lika Drakhlis [...] also suitable for testing pharmacological agents. ‘In some cases, this works even better than in animal models, for example, because these are subject to other biological influences and the results can

patients with CF. Complementary to standard antimicrobial chemotherapy, we are exploring options in animal models to prevent lower respiratory tract infections via local transfer of macrophages, CFTR gene [...] Pseudomonas Genomics Pseudomonas aeruginosa lives in soil, fresh and salt water and colonizes plant and animal surfaces. In humans, P. aeruginosa has become one of the most common bacterial pathogens of local

research group of PD Dr. Nayak, Institute of Molecular and Cell Physiology, Hannover 2022-2024 M.Sc „Animal Biology and Biomedical Sciences”, University of Veterinary Medicine Hannover 2019-2022 B.Sc “Forensic

PhD students are fully financed for 3-4 years. Courses available outside the curriculum include: Animal Handling Gene Technology Omics and Bioinformatics Good Scientific Practise Master Class Lectures

successfully prove that the cell clumps actually grow in the heart tissue and improve organ function in animal models as part of the iCARE project coordinated by Professor Martin. In the new research project [...] biologist. The researchers want to investigate the possible side effect of arrhythmias in a large animal model, which reacts particularly sensitively to disturbances caused by the foreign cardiomyocytes

published study demonstrated the correction of the rare metabolic disease tyrosinemia in experimental animals by injecting adeno-associated viruses (AAV) as a vehicle for CRISPR-Cas9. Various variants of the [...] development. They investigate novel therapeutic concepts in different in vitro , organoids, and small animal model systems to identify effective therapeutic targets for this largely intractable cancer. Research