Pneumology at the Hannover Medical School (MHH) has now taken a decisive step forward in this regard: The team found out that smoking probably plays a causal role in the development of a particularly severe form [...] the Department of Pneumology. Researchers compared three different patient groups In the study, the team compared three different patient groups. The first group consisted of patients with IPAH who had smoked [...] younger, responded better to drug therapies and had a significantly longer life expectancy. The study team concluded that patients with a diagnosis of IPAH and a history of smoking, as well as severely impaired

transplant. For successful treatment, the disease must be detected as early as possible. A research team led by Dr. Richard Taubert, senior physician at the Department of Gastroenterology, Hepatology and [...] another, they can also be detected in other diseases and are therefore not specific. The research team therefore set out to find precise autoantibodies that are typical for AIH and differ from the markers [...] half a day, numerous patients with liver disease could be spared a liver biopsy. The MHH research team has already been able to test the reliability of the new test on several hundred blood samples from

based on many years of research in their respective fields. Two complementary teams, the "Team Transcriptomics" and the "Team Genomics", are in charge of your respective projects. As a central research facility

as informative as possible, and the radiation exposure for patients should be as low as possible. A team from the Institute of Diagnostic and Interventional Radiology at the Hannover Medical School (MHH) [...] this also means additional radiation exposure. The newly developed CT protocol of Professor Shin's team, on the other hand, provides all the information in just one step. To do this, the experts use ph [...] patients in Lower Saxony, who also benefit from the lower radiation exposure of modern CT. The research teams in radiology are working intensively to identify further potential applications, for example in cancer

Whether such cells also exist in the human lung remained controversial in science. Now, a research team led by Professor Dr. Christian Mühlfeld, acting head of the Institute of Functional and Applied Anatomy [...] humans. Final proof through a combination of different detection methods To answer that, the research team took an unusual step. "We combined the different detection methods from various research publications [...] healthy, fibrotic or damaged (emphysematous) human lung tissue provided by Professor Dr. Danny Jonigk's team from the MHH-Institute of Pathology. Dr. Julia Schipke used various markers to highlight different

seriously ill children be improved by rapid genetic diagnosis? This question is being investigated by a team from Pediatrics and Human Genetics at Hannover Medical School (MHH) in the "Baby Lion" study. The [...] rare after all," says Dr. Bernd Auber of the Institute of Human Genetics. For the study, he and his team are focusing on a special patient group: children in their first weeks and -months of life who are [...] Suffering paths can be shortened and unnecessary therapies and examinations can be avoided. Dr. Auber's team now wants to find out whether these findings can also be transferred to the German healthcare system

for drugs." Chemotherapy damages the heart In the REVERSE project, Professor Thum and his research team will first look for circRNAs that control the cardiac remodelling process. This side effect on the [...] selected RNA structures actually control the cardiac remodelling in each case. To do this, the research team uses the method of "living heart slices". These are wafer-thin slices of damaged heart muscle tissue [...] our circRNA candidates in the living heart slices," says the scientist. In a next step, the research team then wants to investigate how they can stop the two different forms of cardiotoxicity. In this way

Team Bachelor of Science in Midwifery Simone Bätge Britta Berkau Ute Borrmann Sarah Faubel Theresa Happe Damaris Lahmann Evelyn Lesta Anne Christine Manawa Ina Mühlmeister Ann-Christine Rengbers Kerstin [...] Kerstin Schulze Frederike Schwark Ulrike Voigt Team at MHH Midwifery Research and Education Unit Prof. Dr. Mechthild Groß, Midwife Director of the Midwifery Research and Education Unit Director of the Midwifery

receiving a further 2.5 million euros for the further development of new antiviral agents. The research team led by Professor Dr Dr Axel Schambach, Head of the Institute of Experimental Haematology at Hannover [...] against emerging infectious diseases. Targeted blocking of virus replication The iGUARD research team is focussing on the parainfluenza virus, which primarily affects the lower respiratory tract in children [...] viruses, so to speak. With the help of artificial intelligence, so-called in-silico design, the research team searched gene databases primarily for "conserved" regions. These are essential for the virus and are

ion between neurones is disrupted. Treatment options are limited and there is no cure. A research team from the Institute of Clinical Biochemistry at Hannover Medical School (MHH) has discovered that the [...] different lengths. Until now, it was unclear whether these also have different functions. The research team is focussing on the short-chain polymers, for which it has been shown that they play an important [...] junctions." The consequences are forgetfulness and dementia. In preliminary studies, the research team was already able to show in a mouse model of Alzheimer's disease that short-chain PolySia of a very