viral hepatitis, autoimmune diseases of the liver, hepatocellular carcinoma, transplantation and regenerative medicine. Professor Manns has been MHH President and Head of Research and Teaching since 2019
[“Molecular Medicine”, “Infection Biology”(& DEWIN: Dynamik der Erreger-Wirt Interaktionen), “Regenerative Sciences”, "Auditory Sciences", "Epidemiology" and "BIOMEDAS - Biomedical Data Sciences"]. There
Project leaders: Daphne DeTemple / Stefan Kalies (NIFE) The liver is known to possess extensive regenerative capabilities, the processes and pathways of which are not fully understood. In order to gain a
tool for the development of new therapies, for example to repair damaged hearts with the help of regenerative medicine. How the many different cell types develop step by step during heart development and
formation of inner hair cells is therefore an important building block for the development of regenerative therapies for the treatment of hearing loss. SERVICE: The original paper "TBX2 specifies and maintains
close collaborations with other projects within the MHH and the Research Center for Translational Regenerative Medicine REBIRTH as well as with the Competence Center for Cardiovascular Implants (Medimplant)
supra-regional catchment area. Its research focuses on transplantation and stem cell research/regenerative medicine, infection and immunity research as well as biomedical technology and implant research
of iPS cells. To guarantee the safety of potential future clinical applications of iPSC-based regenerative cell therapies, we improve our manufacturing protocols for GMP-compatible iPS cell products c [...] heart or the respiratory tract, are associated with genetic defects or mutations. In principle, regenerative therapies are conceivable, in which patient-specific cells are obtained, reprogrammed into iPS [...] optimized for their use in organotypic disease models and screening systems, as well as in cell-based regenerative therapies. Even though extensive information about developmental biology is already accessible
REBIRTH , and receives ongoing support from the 'REBIRTH - Research Center for Translational Regenerative Medicine'. Heart muscle tissue for therapeutic application For a number of cardiovascular diseases
functionality of hPSC-derived cardiomyocytes as test systems and disease models as well as in regenerative medicine? How do hPSC-CMs develop in surrounding tissue in terms of maturation and integration