Institute for Biophysical Chemistry and Division of Structural Biochemistry
Master Thesis Projects
We are looking for motivated biochemistry students interested in combining protein biochemistry with structural biology and computational analysis to work on one of the following topics:
Isoform-specific modulation of cytoskeletal actin dynamics by tropomyosins
Functional characterization of disease-related mutations in cytoskeletal actin and myosin isoforms
You will learn and use the following methods:
-Recombinant production and purification of human proteins
-In vitro reconstitution and analysis of cytoskeletal actin dynamics using multicolour TIRF-microscopy and reconstituted systems from purified proteins
-Steady-state and transient kinetic approaches
-Molecular dynamics simulations
-Next-generation software for the visualization and analysis of molecular structures
Dr. Johannes Greve
I4,S0,R1020
Tel.: 0511-532-3706
Robin Heiringhoff
I4,S0,R1090
Tel.: 0511-532-5174
