Immunology and Infectiology
Prof. Dr. med. Ulrich Baumann
Managing Senior Physician
Hannover Medical School
Center Pediatrics and Adolescent Medicine
Clinic for Pediatric Pneumology, Allergology and Neonatology
OE 6710, Carl-Neuberg-Str. 1, 30625 Hanover
Tel.: +49 511 532-3280
Email: Ulrich Baumann
Pulmonary diseases are the most common complications in patients with congenital disorders of the immune system (immunodeficiencies) and in cystic fibrosis. Increased bacterial infections contribute significantly to the increasing destruction of the airways. We are working to improve the diagnosis of lung diseases using imaging (computed tomography) and functional (Multiple Breath Washout, MBW) techniques. We are developing a functional test to diagnose susceptibility to infections with encapsulated pathogens (e.g. pneumococci). To prevent infection of the lungs with pseudomonas aeruginosa, we are developing a vaccine designed to protect the respiratory tract in particular. To assist patients with everyday problems caused by their primary immunodeficiency, we are developing a structured patient education program and investigating their quality of life.
Assessment of pulmonary antibodies with induced sputum and bronchoalveolar lavage induced by nasal vaccination against Pseudomonas aeruginosa: a clinical phase I/II study.
U. Baumann, K.n Göcke, B. Gewecke, J. Freihorst, B. Ulrich von Specht. Respir Res. 2007 Aug 5;8(1):57.
Immune responses in the airways by nasal vaccination with systemic boosting against Pseudomonas aeruginosa in chronic lung disease.
S. Sorichter, U. Baumann, A. Baumgart, S. Walterspacher, B.-U. von Specht. Vaccine. 2009 May 11;27(21):2755-9.
Systemic, nasal and oral live vaccines against Pseudomonas aeruginosa: A clinical trial of immunogenicity in lower airways of human volunteers.
D. Bumann, C. Behre, K. Behre, S. Herz, B. Gewecke, J. Engelbert Gessner, B.-U. von Specht, U. Baumann. Vaccine. 2010 Jan 8;28(3):707-13.
- EURO-PADnet EU
- BMBF / PID-Net
- BMBF / Kompetenznetz HIV
- Chest CT in ADS Group EU
- The Bindung Site
- BMG / Kompetenznetz
- EU FP7 Programm
- The Binding Site
- Britta Gewecke
- Florian Wölbeling
- Imke Glass
- Marzena Schaefer
- Norbert Gebert