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[Translate to Englisch:] Nationales Konsiliarlaboratorium für Adenoviren

Relevance: 86%
 

iagnostik war die Entwicklung eines quantitativen PCR Verfahrens für humane Adenoviren, das heute als einfaches und schnelles Verfahren zum Adenovirusnachweis verwendet wird. Diese quantitative PCR erfasst [...] molekulare Typisierungsverfahren (Sequenzierung der Neutralisations Determinante), entwickelt, die heute als Routineverfahren zum Einsatz kommen. Zusätzlich besteht heute die Möglichkeit, Adenoviren komplett

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Recommendations for teaching materials

Relevance: 83%
 

Robert Zimmermann Urban & Fischer, 2015, 7. Auflage Cellular and Molecular Immunology Abdul K. Abbas et al. Elsevier, 2017, 9. Edition Basic Immunology: Functions and Disorders of the Immune System Abdul K

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Gnotobiology

Relevance: 82%
 

M., Navarre, W.W., Kiessling, F., Horz, H.P., Torow, N., Cerovic, V., Stecher, B., Strowig, T., et al. (2022). Enhanced cultured diversity of the mouse gut microbiota enables custom-made synthetic communities [...] Basic, M. , Hasler, R., Schmitz, R.A., Krautwald, S., Wolf, A., Stecher, B., Schmitt-Kopplin, P., et al. (2021). Microbial regulation of hexokinase 2 links mitochondrial metabolism and cell death in colitis [...] Rohlfs, M., Klein, C., Muise, A.M., Warner, N., Nambu, R., Mayerle, J., Torok, H.P., … Bleich, A. , et al. (2021). Deficiency in X-linked inhibitor of apoptosis protein promotes susceptibility to microbial

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Aktuelles

Relevance: 81%
 

ihrer Expertise als Partner mitwirken können. Während des Meetings sollen die Projektvorschläge („Gesuche“) vorgestellt werden und sich passende Projektpartner („Angebote“) finden. Als Nebeneffekt der [...] ihrer Expertise als Partner mitwirken können. Während des Meetings sollen die Projektvorschläge („Gesuche“) vorgestellt werden und sich passende Projektpartner („Angebote“) finden. Als Nebeneffekt der

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Methods

Relevance: 80%
 

BR photocycle (Chizhov et al. 1996 ). Note that the ultrafast pump-probe experiments detect another three rate constants in the femto- and picosecond time domains (Dobler et al. 1988 ), thus giving 11 [...] allows transient kinetics to be recorded with a time resolution of few femtoseconds (e.g., Huber et al. 2002 ). The dual pulse method (now is known as pump-probe spectroscopy), initially proposed by Porter [...] mechanism of the actomyosin reaction contains 15 states and 44 rate constants between them (Geeves et al. 1984 ). Most of the kinetic investigations of this reaction were performed using rapid mixing technique

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Funded by the European Research Council

Relevance: 80%
 

SARS-CoV-2 induced pneumonia (Ackermann et al. 2020) ) onto COVID-19 and espcecially their potential long-time consequences. Ackermann M, Verleden SE, Kuehnel M et al (2020) Pulmonary Vascular Endothelialitis

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Scalable process for differentiating pluripotent stem cells into definitive endoderm

Relevance: 77%
 

journal “Nature Protocols” can be found here . Open Access: Sahabian, A., Dahlmann, J., Martin, U. et al. Production and cryopreservation of definitive endoderm from human pluripotent stem cells under defined

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Perner Group

Relevance: 77%
 

studied the interface of the neuropeptide Substance P and skin resident innate immune cells (Perner C. et al. Immunity 2020). With this study they added to an arising field of peripheral neuroimmunology, proving

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Allostery for Medicine

Relevance: 77%
 

and allosteric regulation of UDP-glucose pyrophosphorylase (UGP) [Translate to Englisch:] Cramer et al. (2018) ACS Catalysis. 8:2683-2692. Allosteric mechanisms underlying the enzymatic cycle and catalysis [...] al therapies. Allosteric modulation of innate immune sensors [Translate to Englisch:] Lohöfener et al. (2015) Structure. 23(5):851-862. The innate immune sensors activate interferon-driven antiviral responses

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Methods

Relevance: 77%
 

rational method to discover, validate, and target specific allosteric regulation sites (Cramer et al. , 2018, ACS Catalysis. 8 :2683-2692), which has been successfully applied in our projects. This method

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The MHH Hospital is a maximum care hospital with a nationwide catchment area. The university teaches medicine, dentistry, biochemistry, biomedicine, midwifery and health sciences. The main research areas are Transplantation and Stem Cell Research / Regenerative Medicine, Infection and Immunology Research, Biomedical Engineering and Implant Research.

   

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