Research Clinic for Pediatric Pneumology, Allergology and Neonatology Our research groups are based in the state-of-the-art Pediatric Research Center with 4,500 sqm of research space directly adjacent

Research Center for Translational Regenerative Medicine (Formerly REBIRTH - From Regenerative Biology to Reconstructive Therapy) Description The center was funded from 2006 to 2019 as the Cluster of E

Director Prof. Dr. med. Thomas Werfel Clinic director Secretary 0511 532 7654 0511 532 18854 Derma @ mh-hannover.de To the profile Attending physicians Prof. Dr. med. Bettina Wedi Deputy Clinic Direct

Quality management Darja Holavko, B.A. Management Assistant/Quality Management Officer

Cytoskeleton in Human Diseases Dr. Johannes Greve Medizinische Hochschule Hannover Gebäude I4, Ebene S0 Carl-Neuberg-Str. 1 30625 Hannover Tel: +49-511-532-3706 Mail: greve.johannes @ mh-hannover.de R

Methods Molecular biology Protein production in bacterial and eukaryotic expression systems Protein purification Steady-state and transient kinetics (high-throughput plate-reader assays, stopped-flow)

Current Projects Molecular dissection of mutations in ACTB and ACTG1 causing non-muscle actinopathies Functional characterizations of mutations in non-muscle myosin-2A causing MYH9 -related disorders

Cooperations Nataliya Di Donato (Medizinische Hochschule Hannover, Hannover, Germany) (Project: Actinopathies) Anne-Cécile Reymann (IGBMC, Strasbourg, France) (Project: Actinopathies) Pasquale Bianco

Group Members Group Members Dr. rer. nat Johannes N. Greve Abdul Rahman (PhD student) Alumni Dagmar Abdalla (lab internship, 2025) Marlene Luise Vogelsang (B.Sc. Biology, 2025) Thore Wiebe (B.Sc. Bioc

Teaching Lectures, Practical courses and seminars for biochemistry students (Module: Biophysical Chemistry) Practical courses and seminars for medical students (Module: Biochemistry) Bachelor thesis,