Analysis of connexin 43, connexin 45 and N-cadherin in the human sertoli cell line FS1 and the human seminoma-like cell line TCam-2 in comparison with human testicular biopsies. Schulz B., Schumacher V., Ngezahayo [...] Cell Dev. Biol., Volume 8 – 2020, DOI: 10.3389/fcell.2020.00869. Concatenation of human connexin26 (hCx26) and human connexin46 (hCx46) for the analysis of heteromeric gap junction hemichannels and h [...] Advanced Tissue Culture Models : Biomimetic 3D models of neurodegenerative diseases Development of humanized and animal-free models in order to investigate new therapeutics for neurodegenerative diseases

onal human pluripotent stem cell-derived cardiomyocyte models for investigating cardiac hypertrophy” Wiebke Triebert (RG Zweigerdt): “Bioprocess development for GMP-compliant production of human pluripotent [...] cell-derived cardiomyocytes” Kevin Ullmann (RG Zweigerdt): “Physical and Physiological Control of Human Pluripotent Stem Cells Culture” Mark-Christian Jaboreck (RG Martin): “Development of a hiPSC-based

Archive HEAL Project Graduation 2023 Winter TACTiC Project Graduation 2022 Summer Generation of human induced pluripotent stem cell lines - Encoding for genetically encoded calcium indicators RCaMP1h and [...] organoids - New publication on a detailed protocol for the production of heart-forming organoids from human pluripotent stem cells Teaching Award of the Student Body 2021 - Outstanding Commitment in Teaching [...] research group can replicate early heart development in the cell culture dish for the first time using human stem cells Scalable Process for Differentiation of Pluripotent Stem Cells into Definitive Endoderm

Infektiologie und Endokrinologie ‘Generation of multicellular human liver microtissue models using organoid-derived and direct reprogrammed human hepatocyte-like cells’ Fawaz Ahmad Saleh from the Department [...] Biotechnology & Artificial Organs (LEBAO) ‘Establishing a scalable bioreactor platform to generate human iPSC-derived hematopoietic cell types for regenerative applications’ Ana-Maria Zamfirescu from the

composition of sarcomeric proteins. Subcellular myofibrils can be obtained from human (e.g., biopsies), human-derived and non-human cardiac and skeletal small muscle samples (e.g., mouse, rat, rabbit, zebrafish [...] maturation of human pluripotent stem cell-derived cardiomyocytes; (2) Understanding the effects of missense mutations in sarcomeric proteins on the subcellular and cellular contractile function in human cardiac [...] School; Research topics: Force-related kinetic studies with subcellular myofibrils using human myocardial samples and human embryonic/induced pluripotent stem cell-derived cardiomyocytes. 2011-2013 : Junior

MZP Cardiomyocytes from human induced pluripotent stem cells as a cellular model for hypertrophic cardiomyopathy Researc h focus The focus of our research is the analysis of human induced pluripotent stem [...] β-Myosin heavy chain isoform-expressing myofibrils within human ESC-derived cardiomyocytes recapitulate the contractile features of adult human ventricular myofibrils?, J. Muscle Res. Cell. Motil., 2017 [...] Martin U, Zweigerdt R, Kraft T , Brenner B. Differences in Contractile Function of Myofibrils within Human Embryonic Stem Cell-Derived Cardiomyocytes vs. Adult Ventricular Myofibrils Are Related to Distinct

g communities in humans: an overview using Omics data. mSystems 00130-17. Rath S, Heidrich B, Pieper DH, Vital M (2017). Uncovering the trimethylamine-producing bacteria of the human gut microbiota. Microbiome [...] are colonized by a myriad of microorganisms including bacteria, fungi and viruses – the so-called “human microbiota”. Research efforts in the last decade revealed an important role of microbiota for our [...] we apply “Next- and Third-Generation” Sequencing (NGS) techniques aiming to elucidate the role of human microbiota in health and disease. Bioinformatics and statistical analyses are in focus and coupled

Pharmacology and Toxicology organizes/holds the following courses: MSE_P_301 Pharmacology and Toxicology human medicine, 3rd year of study Organized by: Prof. Dr. rer. nat. Harald Genth (Prof. Dr. med. Ingo Just) [...] of Pharmacology Curriculum Lecture materials MSE_P_509 Clinical Pharmacology and Pharmacotherapy human medicine, 5rd year of study Organized by: Prof. Dr. med. Dirk.O. Stichtenoth, Institute of Clinical [...] Clinical Pharmacology Curriculum more details MSE_P_312 Block internship in internal medicine human medicine, 3rd year of study Organized by: Prof. Dr. Kai Schmidt-Ott, OE 6840, Department of Nephrology and

02.02.2022 Generation of human induced pluripotent stem cell lines Encoding for genetically encoded calcium indicators RCaMP1h and GCaMP6f Calcium plays a key role in cardiomyocytes (CMs) for the translation [...] not-invasive fluorescence imaging technology allows for the monitoring of calcium transients in human induced pluripotent stem cell derived-cardiomyocytes (hiPSC-CMs) to investigate the cardiac elect [...] Bakar, Sylvia Merkert, Alexandra Haase, Ulrich Martin (LEBAO, MHH) Gudrun Göhring (Department of Human Genetics, MHH) The original paper on ScienceDirect.com Further LEBAO Publications For more information

Paper in European Heart Journal Murine and human pluripotent stem cell-derived cardiac bodies form contractile myocardial tissue in vitro, European Heart Journal 2013 For the first time, the team of Ina [...] dimensional cardiomyocyte aggregates, so-called cardiac bodies (CBs), that are based on murine and human pluripotent stem cells. The LEBAO team optimized the processes and investigated the role of fibroblasts [...] S., Krause, A., Drager, G., Ochs, M., Haverich, A., Gruh, I.#, and Martin, U.#. 2013. Murine and human pluripotent stem cell-derived cardiac bodies form contractile myocardial tissue in vitro. European