the network is establishing new tools and expertise for accelerating the development of advanced human induced pluripotent stem cell (iPSC)-based therapies. The project also aims for overcoming scientific [...] to initiate a first-in-man (FIM) clinical trial for the therapeutic administration of allogeneic, human leukocyte antigen (HLA)-homozygous iPSC-cardiomyocyte aggregates, for improving the function of damaged
visceral surgery, radiotherapy, nuclear medicine, (interventional) radiology as well as pathology and human genetics, we consistently discuss every patient with gastrointestinal tumor disease when diagnostic [...] fields of gastroenterology, visceral surgery, radiology, pathology, radiotherapy, nuclear medicine and human genetics Surgical therapies (e.g. laparoscopic and/or robotic resections) by the visceral surgery [...] fields of gastroenterology, visceral surgery, radiology, pathology, radiotherapy, nuclear medicine and human genetics Surgical therapies (e.g. laparoscopic and/or robotic resections) by the visceral surgery
anti-infectives. Microbial metagenome of the respiratory tract The Human Microbiome Project has characterized the microbiome of healthy humans in numerous organs, but has left out the lower respiratory tract [...] Pseudomonas aeruginosa lives in soil, fresh and salt water and colonizes plant and animal surfaces. In humans, P. aeruginosa has become one of the most common bacterial pathogens of local infections of the eye
development of human, stem cell-derived cardiomyocytes (hPSC-CMs) Characterization and further maturation of human, stem cell-derived cardiomyocytes (hPSC-CMs) in direct comparison with human, adult card
accumulation of mutations in somatic cells. For the first time in Germany, iPS cells were generated from human cord blood and differentiated into functional cardiomyocytes. In comparison to iPS cells derived from [...] within the scope of the annual general meeting of the GdF for their publication of iPS cells from human cord blood in the renowned journal Cell Stem Cell (Haase et al. 2009). Once a year, excellent researchers
Linden, Ricklingerstr. 5, 30449 Hannover, project: Regulation of chemokine receptor expression on human eosinophils Final exam on November 7th, 2003 (Dr.rer.nat.) Veit Erpenbeck GERMANY (Dr. med.) supervisor: [...] Sellge GERMANY supervisor: Prof. Dr. Bischoff, Gastroenterology and Hepatology, OE 6810, project: Human intestinal mast cells: versatile cells of the intestinal immune system Final exam on November 7th
Teilprojekt B1 Visualization of herpesviral infections and the immune response and modulation The humane cytomegalovirus (HCMV) causes, in particular in immunosuppressed patients, significant clinical diseases [...] with the murine CMV (MCMV) in the mouse, however, shows many similarities to the HCMV infection in human beings. Although comprehensive infection experiments with MCMV were carried out, the exact processes
Bošnjak Group 07/2023 – 06/2024 RESIST FlexFunds “Deciphering phenotypes, function, and repertoire of human cytomegalovirus-specific CD8+ T cells in elderly”
Biochemistry and Methods (BCB P 15) Master of Science Biochemistry: Instrumental techniques (BCM WP 41) Human Medicine and Dentistry: Biochemistry/Molecular Biology
AG Zweigerdt Zweigerdt Lab Applying human pluripotent stem cells (hPSCs) , we are working on aspects of developmental biology and regenerative medicine focused on the heart as well other tissues and lineages [...] Modulation of Histone Acetyl Transferases (IQ-1) and Wnt pathway (CHIR), synergistically stabilize human cardiac progenitors. SCPs depend on NR2F2 to sustain their progenitor phenotype. Upon removal of the [...] foregut endoderm tissues and a vascular network (Figure 3). Besides deciphering complex mechanisms of human organogenesis in a dish , the HFO model can also be used for replacing animal studies in the process