family. The name DPY-19 comes from the worm C. elegans, where mutations in the C-mannosyltransferase gene lead to a temperature-sensitive DumPY phenotype. In humans there are four homologs of DPY-19, which

European Commission funded consortium: H2020-MSCA-ITN-MATURE-NK Cluster for Future: Saxocell “Cell and gene therapy”

have developed state-of-the-art next generation sequencing and systems biology approaches to examine gene expression patterns and γδ TCR repertoire information, revealing adaptive-like expansions of post

induces cachexia by impeding transcriptional signaling of the SET1/MLL complex on muscle-specific genes . iScience 27: 110913 Wang T, Nayak A , Kraft T, Amrute-Nayak M (2024) Single-Molecule Investigation [...] S (2017) Flightless-I governs cell fate by recruiting the SUMO isopeptidase SENP3 to distinct HOX genes. Epigenetics Chromatin 10: 15 Jung J, Nayak A , Schaeffer V, Starzetz T, Kirsch AK, Muller S, Dikic [...] (2017) Multiplex image-based autophagy RNAi screening identifies SMCR8 as ULK1 kinase activity and gene expression regulator. Elife 6 Brandes RP, Harenkamp S, Schurmann C, Josipovic I, Rashid B, Rezende

(Experimental Hematology) Project: Development of novel tissue-specific AAV vectors for neuromuscular gene therapies Subham Rana , INDIA, Subham.Rana @ mh-hannover.de Supervisor: Prof. Dr. Christian Bär / [...] Lily@mh-hannover.de Supervisor: Prof. Dr. Ruthhild Weber (Human Genetics) Project: Ribosomal biogenesis genes and predisposition to brain tumors Tirthankar Saha , INDIA, Saha.Tirthankar@mh-hannover.de Supervisor:

Azriel S, Rokney A, Valinsky L, Rahav G, Grassl GA*, Gal-Mor O*.Differences in the expression of SPI-1 genes pathogenicity and epidemiology between the emerging Salmonella enterica serovar Infantis and the model [...] Bleich A, Johnsen JM, Vallance BA, Baines JF, Grassl GA. 2015. Expression of the blood-group-related gene B4galnt2 alters susceptibility to Salmonella infection. PLoS Pathogens. 11 e1005008. Grassl GA*, Valdez

REBIRTH, OE 8882, project: Transgenic expression of cytidine deaminase (CDD) and multidrug resistance gene 1 (MDR1) to optimise treatment strategies for acute leukemias and the myelodysplastic syndrome (MDS) [...] Dr. Anuhar Chaturvedi, Molecular Therapy, OE 6864, project: Transcriptional control of MN1 target genes Final exam June 2016. Eileen Hübschen (nee Frenzel) GERMANY supervisor: Prof. Dr. Janciauskiene,

Institute for Toxicology and Experimental Medicine, the Universities of Dresden and Aarhus (Denmark), Gene Center in München, the Institute of Protein Research (Russian Academy of Science), the synchrotron

are fully financed for 3-4 years. Courses available outside the curriculum include: Animal Handling Gene Technology Omics and Bioinformatics Good Scientific Practise Master Class Lectures, Symposia LISA

Ferreira de Figueiredo (Transfusion Medicine) Project: Correction of monogenetic kidney diseases using a gene therapeutic approach Aavani Biju Sindhu INDIA; Sindhu.Aavani @ mh-hannover.de Supervisor: Prof. Dr [...] Felix @ mh-hannover.de Supervisor: Prof. Dr. Axel Schambach (Experimental Hematology) Project: Novel gene therapy strategies for inherited inner ear defects Lena Willmer GERMANY; lena.willmer @ item.fraunhofer