purpose, the initially deregulated ncRNA candidates will be validated by quantitative real-time PCR (qRT-PCR) and correlated with specific patient data. Förderstiftung MHHPlus Hannover IRMI-19 / Immunprofile [...] are included who want to participate in a pulmonary function diagnosis and a fitness test, i.e. a 6-minute walk test, give a blood sample for the definition of their immune profile and answer a questionnaire [...] questionnaire (Fatigue Assessment Scale, FAS). In addition a testing of lung function and endurance (6-MWT) will be performed, as well a blood testing (FACS, ELISA, Neurodisorder assay) to quantify immunologic
e residual disease, or MRD) using the sensitive technique of multi-color flow cytometry (MFC) or qPCR to better predict prognosis. While MRD is widely utilized in leukemia diagnosis and subtype differentiation [...] ELN-DAVID, to implement harmonized MRD assessment practices across Europe, building off of existing MRD testing infrastructure in place in many countries for other leukemias. We will collaborate with colleagues
K., Kempf, H., Zweigerdt, R. , and Mandenius, C. F. 2016. A Microfluidic Bioreactor for Toxicity Testing of Stem Cell Derived 3D Cardiac Bodies. Methods Mol Biol 1502:159. https://doi.org/10.1007/7651_2016_340 [...] 2015. Stem cell derived in vivo-like human cardiac bodies in a microfluidic device for toxicity testing by beating frequency imaging. Lab Chip 15, no. 15:3242. *Authors contributed equally. Effenberg, [...] T., and Martin, U. 2014. Efficient designer nuclease-based homologous recombination enables direct PCR screening for footprint less targeted human pluripotent stem cell clones. Stem Cell Reports 2, no.
COVID-19 / SARS-CoV-2 Research at the MHH Research group of Prof. Dr. Reinhold Förster develops a simple test to detect protective neutralizing antibodies. COVID-19 / SARS-CoV-2 Research at the MHH From basic [...] A, Pink I, Witte T, Wetzke M, Ernst D, Jablonka A, Happle C. Strategic Anti-SARS-CoV-2 Serology Testing in a Low Prevalence Setting: The COVID-19 Contact (CoCo) Study in Healthcare Professionals. Infect [...] nández M, Kaiser FK, Rimmelzwaan G, Osterhaus A, Blume C. Combined Prospective Seroconversion and PCR Data of Selected Cohorts Indicate a High Rate of Subclinical SARS-CoV-2 Infections-an Open Observational