affected. If left untreated, AML leads to death within a few weeks. Already last year, an international study with the participation of Professor Dr. Michael Heuser, Senior Physician at the Department of Hematology [...] of AML patients. Now the hematologist wants to investigate a similar approach in a new multicenter study. This will involve combining one of the drugs already being tested with another agent that has so [...] with chronic kidney disease. Volunteers are still being sought who would like to take part in the study. German Cancer Aid is funding the project with one million euros over four years. Combination therapy

boys. Researchers at the Hannover Medical School (MHH) have now been able to show this in a European study. Although the mortality rate in children after kidney transplantation has fallen in recent decades [...] explain the higher mortality of girls with kidney failure," says Dr Rizky Sugianto, lead author of the study. "We show that girls with advanced chronic kidney disease are more prone to developing vascular stiffness [...] suffer more from limited kidney function and the waiting time for an organ, according to a European study they are also less likely than boys to receive a pre-emptive transplant, i.e. a transplant before

a comparative value for other studies in the future. "So far, only the findings of children with different diseases could be compared," explains the scientist. The study also gives a decisive indication [...] (mucoviscidosis) and found out how a healthy microbiome of the lower respiratory tract develops. The study was published in the renowned journal Biofilms and Microbiomes. Microorganisms form a community "Until [...] human lower respiratory tract was considered sterile," explains Professor Tümmler. Therefore, most studies had only examined the microbiology of the lungs in acute infections or chronic lung diseases. "In

people affected to be higher. "We get a new case every week," he says. Larger studies necessary to confirm data In the CLEAN-PCD study, the researchers tried to restore the osmotic effect of saline and increase [...] into the blood via the so-called epithelial sodium channel (ENaC). In the transatlantic CLEAN-PCD study, an international team led Dr Felix Ringshausen, senior physician at the Department of Pneumology [...] transported away more easily, which measurably improved lung function in the patients. The results of the study are published in the journal The Lancet Respiratory Medicine. Difficult to diagnose "PCD is a severe

Department of Pneumology and Infectious Diseases at Hannover Medical School (MHH), which supervised the study as the lead centre. The results have been published in the New England Journal of Medicine , a leading [...] hypertension decreases significantly More than 320 people with PAH from 20 countries took part in the study. More than half of them suffered from severe symptoms despite maximum therapy with three drugs. The [...] worsening or dying decreased by more than 80 per cent compared to standard therapy. "Some of our study participants were able to leave the intensive care unit after treatment with Sotatercept and resume

well as the Pathology Institute of the University Hospital Heidelberg cooperated for the study. The study was funded, among others, by the German Research Foundation, the Niedersächsische Krebsgesellschaft [...] cholangiocarcinoma (CCA), have been inadequate, while the number of new cases has been rising. A study by researchers at the Hannover Medical School (MHH) and the Helmholtz Centre for Infection Research [...] keeps the growth of the liver tumour under control," explains Dr Tetyana Yevsa, coordinator of the study and head of the research group in the Department of Gastroenterology, Hepatology and Endocrinology

Children With Fanconi Anemia and Ataxia-Telangiectasia - A Nationwide Register-Based Cohort Study in Germany". The study was supported by the Federal Ministry of Education and Research (BMBF), the German Childhood [...] University Mainz and the University Hospital Freiburg now conducted a nationwide register-based cohort study to precisely determine the risk of cancer in children with FA and AT. The team observed a drastically [...] drastically increased risk of cancer in the affected children compared to the general population. Study results support patient counselling "Based on our results, the risk of developing cancer before the age

the systemic effects and implications that the anti-ageing effect of spermidine can lead to. The study in cooperation with the University of Graz has been published in the scientific journal GeroScience [...] substance that occurs in every cell. With age, its concentration in the cells decreases. "In our study, we investigated how prolonged spermidine administration affects organs commonly affected by age and [...] The research group of neurophysiologists, nuclear medicine specialists and molecular biologists studied the effects in aged mice and gave the animals spermidine through their drinking water for six months

loses its function. In a European study, researchers have now developed an index that can be used to predict the risk of cirrhosis or other serious liver diseases. The study was conducted as part of the " [...] Frank Lammert, Vice President of the Hannover Medical School (MHH) and one of the authors of the study, which has just been published in The Lancet, a leading medical journal worldwide. Early risk assessment [...] cancer and die from the disease," says Professor Dr Michael Manns, MHH President and co-author of the study. "By calculating the risk early, preventive measures such as exercise and a healthy diet can help

hypothesis of the study. "If we know these mediators and their concentration in the blood, new therapeutic preventive approaches could be developed specifically." 5,000 blood samples will be studied The three [...] Gerrit Große from the Department of Neurology at Hannover Medical School (MHH) is coordinating the study. The project is funded by the European research network ERA-NET NEURON with 770,000 euros for three [...] three consortium partners are contributing their specific methodological expertise to the study and will evaluate blood samples from a total of 5,000 patients. In doing so, they will focus on a large number