risk of cancer in the affected children compared to the general population. Study results support patient counselling "Based on our results, the risk of developing cancer before the age of 18 is 11 per cent [...] Prevention/Predisposition at the Comprehensive Cancer Center (CCC) Hannover of MHH. Data from 581 patients analysed In total, data from 581 affected individuals diagnosed between the years 1973 and 2020 [...] disorders in Würzburg (FA and AT) and Hannover (AT) were analysed. The researchers identified 421 patients with FA and 160 with AT. With the help of an encryption algorithm to pseudonymise the data, a comparison

project relies on so-called induced pluripotent stem cells (iPS cells), which can be obtained from patients’ somatic cells by a technology known as “somatic cell reprogramming”. The special feature of the [...] be used to generate specific replacement cells in a dish, which subsequently can be returned to a patient as a cure. MHH scientists have recently enabled continuous production of iPS cell-derived functional [...] eliminate disease-causing bacteria. Therefore, they have the great potential, for example, for treating patients with severe bacterial infection of the lungs (pneumonia), which do not respond to antibiotics. "The

analysed 225 scientific publications for their article. "Gene therapies are increasingly reaching patients, as the many clinical studies that we have analysed show," explains Professor Büning. But this is [...] particularly important to the authors that the approved gene therapies are then also accessible to patients. "Unfortunately, this has not yet been ensured," emphasises Professor Schambach. Success is based [...] interdisciplinary collaboration between doctors, researchers, ethicists, regulatory authorities and patient organisations," Professor Schambach is certain. It is also always necessary to critically assess

a new electrophysiology laboratory: this is a cardiac catheterisation laboratory especially for patients with cardiac arrhythmias. The modern facility offers all diagnostic and therapeutic possibilities [...] Examination with the aid of magnetic field navigation There are many proven treatment options for patients with cardiac arrhythmias. They range from medication to catheter ablation, i.e. the obliteration [...] the new procedure as a great gain. "It is gentler and faster and thus offers more safety for our patients." The HHC is the first facility in Hanover to offer pulsed field ablation. New opportunities for

logy, Hepatology and Endocrinology at the MHH. As a Clinical Scientist at the interface between patient care and basic research, she significantly advances the further development of therapeutic approaches [...] innere Medizin" (Internal Medicine) and of the first guide to cancer immunotherapy. Treating cancer patients in an appropriate way Cancers of the bile ducts and liver are the special field of PD Dr. Anna [...] challenges of a "dual career" in science and research: on the one hand, she is involved in the care of patients with gastrointestinal tumour diseases as a doctor, and on the other, she heads a basic science research

single-chamber heart with three million euros for three years. Such an implant could, for example, help patients with congenital heart defects in whom only one chamber of the heart works for hereditary reasons [...] ventricle is present or functional from birth, it supplies both the body and lung arteries. "These patients have mixed blood in the heart and have to undergo a so-called Fontan operation in childhood, in [...] ventricle is present or functional from birth, it supplies both the body and lung arteries. "These patients have mixed blood in the heart and have to undergo a so-called Fontan operation in childhood, in

School (MHH) wants to change this situation. The Amyloidosis Centre Lower Saxony founded there offers patients diagnostics, care and therapy at one location. Many experts work together on an interdisciplinary [...] the Centre for Rare Diseases (ZSE) at the MHH. It was founded at the end of 2020, and around 200 patients with amyloidosis are now being cared for there. Since the centre was founded, the numbers and referrals [...] investigating the causes of amyloidosis, the effect of drugs against the disease and the development of patients during therapy," explains Professor Skripuletz. Contact: Hanover Medical School, Centre for Rare

seven years after diagnosis. New hope has now been given by an international clinical trial in which patients were treated with the new drug Sotatercept in addition to their existing therapy. "We were able [...] performance as well as a reduction in blood pressure in the lungs. At the same time, the risk of the patients' condition worsening or dying decreased by more than 80 per cent compared to standard therapy. "Some [...] Olsson, senior physician at the MHH clinic and co-author of the study. "We were even able to take patients off the transplant list who were already scheduled for a lung transplant." In most cases, pulmonary

1968. In 1975, Borst's team had treated more than 1,000 patients with the support of the heart-lung machine, and by 1986 the number of patients had risen to 10,000. By this time, the MHH had already developed [...] Dr. Rudolf Zenker was one of the first in the German-speaking area to successfully operate on a patient's open heart with its help at the University Hospital in Marburg. At the MHH, Professor Borst first

increased pressure. Blood samples from these patients showed significantly elevated levels of MYDGF. When an artificial heart valve was implanted in the patients in the cardiac catheterisation laboratory [...] of the study. Whether all of this is also significant for humans was investigated by the team in patients with heart failure due to aortic stenosis. In this disease, the heart valve between the ventricle