Transfusion Medicine and Transplant Engineering . Hereditary primary haemochromatosis is one of the most common inborn errors of metabolism in Europe. The cause is a genetic defect that disturbs the regulation [...] approach, but also for translational application in other monogenetic diseases and those in which genetic effectors play a central role. The prize was awarded on 1 July during the 19th HepNet Symposium.

by Professor Dr Rainer Blasczyk, head of the Institute for Transfusion Medicine and Transplant Engineering at the Medical School (MHH), wants to solve this problem. The aim is to use molecular biological [...] research team produces them in cell culture from induced pluripotent stem cells (IPSC). These are genetically reprogrammed body cells that have similar properties to embryonic stem cells, i.e. they can develop [...] Figueiredo, senior scientist at the Institute and deputy project leader. In addition, the scientist genetically modified the iPSC and also switched off the HLA characteristics of the cells. The result is a kind

Bettina Wiegmann, who heads three of the four MHH projects at the Lower Saxony Center for Biomedical Engineering, Implant Research and Development (NIFE). The scientist hopes to prevent this thrombus formation [...] g endothelial cells. "These endothelial cells, which are not endogenous to the body, are also genetically modified so that they are virtually invisible to the patient's immune system and are therefore [...] Dr. Constanca Ferreira de Figueiredo from the Institute of Transfusion Medicine and Transplant Engineering. A fourth is based at the Leibniz Research Laboratories for Biotechnology and Artificial Organs

percent of all people worldwide without most even noticing it. But once it enters the body, the genetic material of the pathogen remains dormant there. If the immune system is weakened or shut down by [...] Dr. Britta Eiz-Vesper, immunologist at the MHH Institute of Transfusion Medicine and Transplant Engineering . Because the institute is not only one of Germany's leading producer for virus-specific T cells [...] Neurology with Clinical Neurophysiology, the Institute for Transfusion Medicine and Transplant Engineering, the Institute for Diagnostic and Interventional Radiology , the Department of Paediatric Haematology

applied stem cell-based therapies and has extensive expertise in somatic cell reprogramming, genetic engineering, bioprocessing and preclinical testing, particularly in the areas of heart, liver and lung

all people worldwide without most of them even noticing it. But once it has entered the body, the genetic material of the pathogen remains dormant. If the immune system is weakened or shut down by a serious [...] Britta Eiz-Vesper, immunologist at the MHH Institute for Transfusion Medicine and Transplant Engineering. As the institute is not only one of Germany's leading manufacturing sites for virus-specific T [...] Neurology with Clinical Neurophysiology, the Institute of Transfusion Medicine and Transplant Engineering, the Department of Paediatric Haematology and Oncology, the Department of Pneumology and the Institute

Institute of Genetics at the Faculty of Natural Sciences at the University of Bonn, where he habilitated in genetics and immunology in 1993. In the same year, he was appointed Professor of Tumour Genetics at the [...] succeeded in casting the initial idea of a directed T-cell response into a solid concept of "CAR engineering", which has been taken up by many groups at home and abroad and is constantly being further developed

vectors dock onto the body cell via the vector envelope, the so-called capsid, and transfer their genetic cargo into the cell interior. There it is read and converted into the corresponding protein according [...] Christian Bär, baer.christian@mh-hannover.de , phone (0511) 532-2883. The original paper "AAV capsid engineering identified two novel variants with improved in vivo tropism for cardiomyocytes" can be found here

team led by Dr Anna Christina Dragon from the Institute of Transfusion Medicine and Transplant Engineering at Hannover Medical School (MHH) is now developing a new type of cell therapy to preserve organ [...] immune cells of the patient – the so-called T cells – which we convert into killer cells through genetic modification so that they precisely eliminate the responsible B cells that would otherwise produce