developed standard procedures for the isolation, activation and propagation of T and NK cells of the human immune system, which we make available to researchers at the MHH as well as to external companies [...] types and capture it in a time-lapse video. A look into the microscope, for example, shows whether human T cells such as CARs and TRUCKs, which have been genetically modified in the laboratory, actually

they communicate with cells of the acquired immune system in the HCC tumor. To do this, samples of human tumor tissue are compared with healthy liver tissue and analyzed to determine which immune cells are [...] response. If the therapeutic approaches work in the mouse model, they could then be tested in a human clinical trial. "This is an ambitious four-year program," Dr. Heinrich admits. "However, we hope to

Hypertrophic Cardiomyopathy: Contractile Imbalance as a central pathomechanism? Investigations on human myocardium and cellular models. Research focus One of our central goals is to elucidate how mutations [...] of the institute Teaching Lecture in "Physiology and Physical Basics of Medicine" for students of human medicine (HM) and dentistry (ZM) in the 1st and 2nd year of study on the topics of skeletal muscle

Haverich, A., and Hilfiker, A. 2018. Human adipose tissue-derived stromal cells in combination with exogenous stimuli facilitate three-dimensional network formation of human endothelial cells derived from various [...] H., and Hilfiker, A. 2020. Dot blots of solubilized extracellular matrix allow quantification of human antibodies bound to epitopes present in decellularized porcine pulmonary heart valves. Xenotransp [...] three-dimensional tubular endothelial cell networks under defined serum-free cell culture conditions in human collagen hydrogels, in: Scientific Reports 9, Article number: 5437 Sarikouch S, Theodoridis K, Hilfiker

where mutations in the C-mannosyltransferase gene lead to a temperature-sensitive DumPY phenotype. In humans there are four homologs of DPY-19, which are called DPY19L1, DPY19L2, DPY19L3, and DPY19L4.

xander-University of Erlangen-Nürnberg (FAU) Integrative bioinformatics analysis and modeling of human physiology 18 June 2020 Prof. Christian Wahl-Schott, MHH (Institute of Neurophysiology) Second me

A., Dahlmann, J., Martin, U. et al. Production and cryopreservation of definitive endoderm from human pluripotent stem cells under defined and scalable culture conditions. Nat Protoc 16, 1581–1599 (2021)

students of Life Sciences, Medicine and Engineering (Biology, Biochemistry, Biotechnology, Biomedicine, Human Biology, Medicine, Veterinary Medicine, Pharmacology) with strong interest in Immunology - basic sciences

biohybrid devices. Structural characterization of the actomyosin complexes produced in Dictyostelium and human cells and elucidation of their involvement in cytokinesis and cell motility. Structure-based iden

longterm EMBO Fellow (1988-90) and Clinical Research Scientist (1990-1995), where he worked on the human retroviruses HIV-1, HIV-2 and HTLV-1, and, from 1994 onwards, on KSHV/HHV8. He was appointed as full [...] Guigen, PhD Schulz lab Main research topic KSHV lab Kaposi Sarcoma-associated Herpesvirus (KSHV), or Human Herpesvirus 8 (HHV8), is the infectious cause of Kaposi’s sarcoma (KS), an endothelial cell – derived [...] associated with AIDS. KSHV was discovered by Yuan Chang and Pat Moore in 1994 and is one of the seven human cancer viruses recognized by the International Agency for Research against Cancer (IARC), a WHO agency