logy, Hepatology and Endocrinology at the MHH. As a Clinical Scientist at the interface between patient care and basic research, she significantly advances the further development of therapeutic approaches [...] innere Medizin" (Internal Medicine) and of the first guide to cancer immunotherapy. Treating cancer patients in an appropriate way Cancers of the bile ducts and liver are the special field of PD Dr. Anna [...] challenges of a "dual career" in science and research: on the one hand, she is involved in the care of patients with gastrointestinal tumour diseases as a doctor, and on the other, she heads a basic science research
single-chamber heart with three million euros for three years. Such an implant could, for example, help patients with congenital heart defects in whom only one chamber of the heart works for hereditary reasons [...] ventricle is present or functional from birth, it supplies both the body and lung arteries. "These patients have mixed blood in the heart and have to undergo a so-called Fontan operation in childhood, in [...] ventricle is present or functional from birth, it supplies both the body and lung arteries. "These patients have mixed blood in the heart and have to undergo a so-called Fontan operation in childhood, in
airway microbiology, electrophysiology and genetics in patients with CF (see publications ). Through our many years of clinical work with CF patients, we have long-term histories and biomaterial collections [...] pathways triggered by them could represent promising targets for new therapeutic approaches in CF patients, for example. Innate lymphoid cells (ILCs) localized in the airway mucosa play a critical role in [...] we are investigating the composition, phenotype and function of ILCs in lung tissue from human CF patients and in a mouse model of CF-like disease (bENaC mice) using advanced deep phenotyping methods such
university and non-university research institutions in the field of pneumology. Basic, disease-, and patient-oriented research in the field of lung diseases is supposed to be coordinated based on the centre [...] efficiently the translation of basal scientific findings into clinical concepts for the improvement of patient care. The network of the three research institutions is located in Hannover and is going to bear
ific mutations in patient-derived iPSCs. This method is not only of utmost importance for the investigation of disease mechanisms and for the generation of disease-corrected, patient-derived iPSC lines
parents. Our highly specialized and dedicated team of doctors and pediatric nurses take care of the patients with a lot of experience and intensive attention. The latest technology and modern equipment on [...] on the ward ensure first-class medical and highly competent care. When treating the little patients, we work together with the other clinics and institutes of the Hannover Medical School, such as Pediatric
myopathies including cancer cachexia, prevalent in nearly 80% of cancer patients with reported mortality rate in more than 30% patients. The major focus of our group is understand how SUMO (Small Ubiquitin-like [...] extent of functional changes caused by HCM mutations in cardiomyocytes of affected heterozygous patients is very different among cardiomyocytes isolated from the same tissue. For example, some cardiomyocytes [...] show for β-cardiac myosin heavy chain (β-MyHC) and cardiac troponin I (cTnI) that in each of the patients studied, individual cardiomyocytes from the same tissue express very different proportions of mutated
clinical and epidemiological methods to further improve early diagnosis and quality-based treatment of patients with acute kidney or kidney transplant disease. We pay special attention to the exploitation, c [...] goal is to use the knowledge gained to improve prediction, clinical classification, and therapy in patients* with kidney disease. Cooperation partners Institut für Sozialmedizin, Gesundheitssystemforschung [...] ChAd/BNT compared with homologous BNT/BNT and ChAd/ChAd SARS-CoV-2 vaccination in hemodialysis patients: A multicenter prospective observational study. Journal of Nephrology, 35,1467-1478, 2022. Haarhaus
School (MHH) wants to change this situation. The Amyloidosis Centre Lower Saxony founded there offers patients diagnostics, care and therapy at one location. Many experts work together on an interdisciplinary [...] the Centre for Rare Diseases (ZSE) at the MHH. It was founded at the end of 2020, and around 200 patients with amyloidosis are now being cared for there. Since the centre was founded, the numbers and referrals [...] investigating the causes of amyloidosis, the effect of drugs against the disease and the development of patients during therapy," explains Professor Skripuletz. Contact: Hanover Medical School, Centre for Rare
in advanced organ failure and thus improve patient care. Current therapies are symptomatic, and the lack of donor organs places an additional burden on patients and their families. R-CUBE will develop multimodal [...] know the patients' situation very well, and the researchers, who are investigating the fundamentals in order to enable better prevention, diagnosis and treatment. In order to be able to help patients, basic [...] regeneration and repair and offer novel strategies for organ replacement. As world-leading center for patients with organ diseases, the transplantation spectrum of MHH ranges from abdominal and thoracic organs