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Welcome to the MHH
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TACTIC

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for individualized Cell Therapy with iPSC-derived Cardiomyocytes Preclinical evaluation in a non-human primate model and a roadmap for clinical application The Federal Ministry of Education and Research

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Projects

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Mikrobiom e.V. - "Therapeutic immunization against commensal microbiota to attenuate GvHD in mice and humans" Applicant: PD Dr. Christian Könecke Cooperation with Prof. Dr. O. Pabst, RWTH Aachen 09/2013 - 08/2016

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Zhong Huang MD, PhD

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engineering. Huang Z, Powell R, Phillips J B, et al. Cells, 2020, 9(11): 2497. Culture Conditions for Human Induced Pluripotent Stem Cell-Derived Schwann Cells: A Two-Centre StudyHuang, Z., Powell, R, Kankowski

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10th German Pharm-Tox Summit

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March 27th 2025 from 14.00 – 14.50 in lecture hall A by Prof. Koos Burggraaf from the Center for Human Drug Research (CHDR) in Leiden, the first academic-led center for early clinical drug development

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[Translate to Englisch:] AG Voss (Emmy Noether Nachwuchsgruppe)

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alveolar lung organoids obtained either from murine adult stem cells or via directed differentiation of human iPS cells into functional type 2 alveolar epithelial cells. By co-culturing immune and structural [...] H. B. 2020. Alveolar regeneration through a Krt8+ transitional stem cell state that persists in human lung fibrosis. Nat Commun 11, no. 1:3559. https://doi.org/10.1038/s41467-020-17358-3 .

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Students 2023

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Ganbat Research Topic: Immunosuppressive effects of the RL11 family glycoproteins pUL11 and pUL10 from Human Cytomegalovirus Supervisor: Dr. Penelope Kay-Fedorov, Institute of Virology, MHH Academic Background: [...] Topic: Functional and phenotypical characterization of peptide-specific PLZF+ innate-like T cells in humans Supervisor: Dr. Hristo Georgiev, Institute of Immunology, MHH Academic Background: Biochemistry,

News

Biological heart chamber from the laboratory

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support system. So-called induced pluripotent stem cells (iPS cells) from genetically reprogrammed human tissue cells are used to produce heart muscle cells and blood vessel-lining endothelial cells. These [...] emphasises. Later clinical studies will then show whether the heart prosthesis from the MHH also works in humans. Who does what? For the 3D Heart 2B project, an interdisciplinary team from the fields of biology

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Research focus

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pro-inflammatory cytokines in response to airway epithelial signals. We have recently shown that ILCs in human CF lungs produce the pro-inflammatory cytokine IL17A. In a murine model of CF-like lung disease, we [...] this end, we are investigating the composition, phenotype and function of ILCs in lung tissue from human CF patients and in a mouse model of CF-like disease (bENaC mice) using advanced deep phenotyping methods

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Year 2017

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Final exam November 2022. Janin Bublitz GERMANY Supervisor: Prof. Dr. Doris Steinemann, Institute of Human Genetics, OE 6300 Project: Nachweis und Bedeutung von strukturellen Genom-Varianten beim familiären [...] Department of Pneumology, OE 6870 Project:Characterization and modulation of the systemic and pulmonary human immune response after allergic, inflammatory and infectious provocation. Final exam November 2021

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Research projects

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and rehabilitation. On the other hand, digital bioethics, in analogy to the digital/computational humanities, means the use of digital methods in bioethical research: digital bioethics uses digital tools [...] S (2025): Metaphors in Digital Radiology: Ethical Implications for responsibility assignments of Human-AI Imaginaries. AI & Society (accepted). Hologram techniques for Digital Surgery: An Analysis of Ethical

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The MHH Hospital is a maximum care hospital with a nationwide catchment area. The university teaches medicine, dentistry, biochemistry, biomedicine, midwifery and health sciences. The main research areas are Transplantation and Stem Cell Research / Regenerative Medicine, Infection and Immunology Research, Biomedical Engineering and Implant Research.

   

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