in the blood of AIH patients. "They have the special property of being able to bind with very many human proteins," explains the gastroenterologist. New test closes diagnostic gap These so-called polyreactive
to evaluate data," says Dr Jack. However, medical decisions are not made by the system, but by the human being, the physician emphasises. "ELISE is just a kind of co-pilot that, as a digital companion, frees
sms of hypertrophic cardiomyopathy, physiology and pathophysiology of skeletal muscle fibers and human cardiomyocytes, molecular aspects of contraction and motility
Hereditary Chronic Pancreatitis and Their Families: A Qualitative Triangulation. European Journal of Human Genetics 29(1):29-38. Seidlein AH*, Hannich A*, Nowak A, Gründling M, Salloch S (2020): Ethical aspects
huge impact for both the optimization of differentiation protocols as well as for drug-screening are human iPS reporter cell lines which are generated using TALEN-based homologues recombination ( RG Martin
Shaheed IB, Mosimann C, Diecke S, Schmidt-Ott KM . The centrosomal protein 83 (CEP83) regulates human pluripotent stem cell differentiation toward the kidney lineage. Elife, 11:e80165, 2022. Hinze C, [...] Rajewsky N, Schmidt-Ott KM . Single-cell transcriptomics reveals common epithelial response patterns in human acute kidney injury. Genome Medicine, 14:103, 2022. Hinze C, Karaiskos N, Boltengagen A, Walentin
levels have been shown to decrease as the disease progresses. "In studies on the mouse model and in human liver cells, we have already been able to show that the therapeutic mRNA can be used to restore HFN4α
transferable as possible for widespread use. However, the chip systems will not only be equipped with human stem cells. The researchers also want to replicate animal models. "Many very fundamental investigations
ducts and gallbladder. BCTs are rare and account for less than one percent of malignant neoplasms in humans. Overall, BCT have a poor prognosis. Five years after diagnosis, only 10 to 20 percent of those affected
nephrology, gastroenterology, immunology, nuclear medicine, pathology, plastic surgery, paediatrics, human genetics and radiology. All those involved work in close cooperation. "The diagnosis and treatment