dose e.V.”, technologies are currently being developed to correct the underlying gene defect in patient-derived iPSCs prior to differentiation into the desired respiratory cell type (see also RG Martin

Learning booths Learning management system (ILIAS) Learning program AMBOSS Lending period Library for patients and MHH members Literature Administration Programs and Citation Regulations Lockers LUIS manuals

N , Meyer B, Heidrich B, Wedemeyer H, Maasoumy B, Tergast TL. Comparison of clinical outcomes in patients with refractory ascites treated with either TIPS, tunneled peritoneal catheter, or ascites pump [...] Hahn T, Wedemeyer H, Seeliger B, Lenzen H, Stahl K. Percutaneous transhepatic biliary drainage in patients with cholestasis following liver transplantation. Abdom Radiol (NY). 2024 Nov 5. doi: 10.1007/s [...] Luetkens J, Kalff JC, Strassburg CP, González-Carmona MA. The impact of lenvatinib on sarcopenia in patients with advanced unresectable hepatocellular carcinoma. Sci Rep. 2024 Sep 27;14(1):22146. doi: 10.

es with students. "RNA therapeutics are the drugs of the future and have several advantages for patients, such as safety and efficacy compared to other approaches," explains Professor Sharma. Keyword

expression of mutated and wild-type protein in the individual cardiomyocytes of heterozygous HCM patients leads to a functional imbalance between the cardiomyocytes in the syncytium of the heart muscle

in vitro models to study hypertrophy and fibrosis. Currently, we have extended this model using patient-specific iPSCs for disease modeling to investigate genetic causes of cardiovascular diseases and

myopathies including cancer cachexia, prevalent in nearly 80% of cancer patients with reported mortality rate in more than 30% patients. The major focus of our group is understand how SUMO (Small Ubiquitin-like

A, Wollert KC. Plasma concentrations of myeloid-derived growth factor in healthy individuals and patients with acute myocardial infarction as assessed by multiple reaction monitoring-mass spectrometry. [...] induced pluripotent stem cell-derived cardiomyocytes generated from duchenne muscular dystrophy patients. J Cell Mol Med. 2019;23:2125-2135. https://pubmed.ncbi.nlm.nih.gov/30618214 Sonnenschein K, Wilczek [...] Veltmann C, Hilfiker-Kleiner D, Bauersachs J. Long-term follow-up in peripartum cardiomyopathy patients with contemporary treatment: Low mortality, high cardiac recovery, but significant cardiovascular

Methylation of the t-PA Gene Differs Between Various Immune Cell Subtypes Isolated From Depressed Patients Receiving Electroconvulsive Therapy. Moschny N, Jahn K, Bajbouj M, Maier HB, Ballmaier M, Khan AQ [...] immune cell ratios, and their association with seizure quality and clinical outcome in depressed patients. Moschny N, Jahn K, Maier HB, Khan AQ, Ballmaier M, Liepach K, Sack M, Skripuletz T, Bleich S, Frieling [...] PMID: 18712725 A new population of myeloid-derived suppressor cells in hepatocellular carcinoma patients induces CD4(+)CD25(+)Foxp3(+) T cells. Hoechst B, Ormandy LA, Ballmaier M, Lehner F, Krüger C, Manns

l characterization of myofibrils from human embryonic and induced pluripotent stem cells of FHC-patients”, Institute of Molecular and Cell Physiology, Hannover Medical School (funding: DFG) 2013-2014 : [...] guinea-pig, rabbit, zebra-fish); (2) Sarcomeric proteins and functional phenotype in pediatric patients with conotruncal congenital heart defects; (3) Establishment of the small-perturbational sinusoidal [...] of the Agronomic Sciences and Veterinary Medicine, Bucharest) Publications / Original Research Patient-specific hiPSC-derived cardiomyocytes indicate allelic and contractile imbalance as pathogenic factor