2122467120 A specific, non-immune system-related isoform of the human inducible nitric oxide synthase is expressed during differentiation of human stem cells into various cell types. Gather F, Ihrig-Biedert [...] Gather F, Vogel T (2022) Int J Mol Sci. 23(2):954. https//doi.org/10.3390/ijms23020954 Regulation of human inducible nitric oxide synthase expression by an upstream open reading frame. Gather F, Schmitz K

the human induced pluripotent stem cell derived cardiomyocytes (hiPSC-CMs) and further validate these findings in living myocardial slices isolated from left ventricular specimens of failing human hearts [...] the hiPSC-CMs and live human myocardial slices with the SARS-CoV-2 virus and analyze the transcriptome to identify potential non-coding RNAs involved in this process. Impact of human glycosylation on the [...] protein levels in rat primary cardiomyocytes. More importantly these findings were also translated into human induced pluripotent stem cell derived cardiomyocytes. We reported the first miRNA candidate that can

Berechnung von Pflegeunterstützungsgeld bei kurzzeitiger Arbeitsverhinderung ) Support from Human Resources Human Resources, service agreements, collective agreements The Service agreements of MHH (e.g. [...] The collective agreements are available on the forms page of Human Resources. If you have further questions, the contact person in Human Resources are happy to assist you. A family member needs care — [...] — what now? An overview is provided on the family page of Human Resources with information on maternity protection, parental leave, and caregiving situations. For any questions related to balancing work

are using heart muscle cells from human induced pluripotent stem cells. These are "reprogrammed" body cells from adults that can give rise to any cell type in the human body - including heart muscle cells [...] platform with which a COVID course can be generated that is similar and thus comparable to that of humans. The results should then explain in more detail which mechanisms the corona virus uses to weaken

library among more than one million AAV variants, which function both in mouse liver cells and in human liver cells. "This cross-species application possibility is very important for the development of [...] necessary preclinical trials in the mouse model and their transfer to the later clinical trials in humans," explains the molecular biotechnologist. AAV vector variants already successful in mice against [...] have to be confirmed in further studies in large animal models and later also in clinical studies in humans. More than 400 monogenetic diseases are known for the liver. So there could be many more transport

anti-infectives. Microbial metagenome of the respiratory tract The Human Microbiome Project has characterized the microbiome of healthy humans in numerous organs, but has left out the lower respiratory tract [...] Pseudomonas aeruginosa lives in soil, fresh and salt water and colonizes plant and animal surfaces. In humans, P. aeruginosa has become one of the most common bacterial pathogens of local infections of the eye

accumulation of mutations in somatic cells. For the first time in Germany, iPS cells were generated from human cord blood and differentiated into functional cardiomyocytes. In comparison to iPS cells derived from [...] within the scope of the annual general meeting of the GdF for their publication of iPS cells from human cord blood in the renowned journal Cell Stem Cell (Haase et al. 2009). Once a year, excellent researchers

Teilprojekt B1 Visualization of herpesviral infections and the immune response and modulation The humane cytomegalovirus (HCMV) causes, in particular in immunosuppressed patients, significant clinical diseases [...] with the murine CMV (MCMV) in the mouse, however, shows many similarities to the HCMV infection in human beings. Although comprehensive infection experiments with MCMV were carried out, the exact processes

Linden, Ricklingerstr. 5, 30449 Hannover, project: Regulation of chemokine receptor expression on human eosinophils Final exam on November 7th, 2003 (Dr.rer.nat.) Veit Erpenbeck GERMANY (Dr. med.) supervisor: [...] Sellge GERMANY supervisor: Prof. Dr. Bischoff, Gastroenterology and Hepatology, OE 6810, project: Human intestinal mast cells: versatile cells of the intestinal immune system Final exam on November 7th

processing of fresh human tissue and body fluids, as well as biobanking and long-term storage. We are thus generating readily available, expert-assessed and extremely valuable tissues from human and animal hearts [...] LV-endomyocardial biopsies from the DETECT-ID registry. We will characterize the function of isolated human cardiomyocytes from hearts with dilated cardiomyopathy with and without ID. In a new mouse model of [...] repair during cardiac remodeling The aim in the second funding period is to translate these results to human ex-vivo models and to the porcine TAC model as a clinically relevant animal model, to study the in