Conference Presentations (Selection) - Dr. Manuel Taft Conference Presentations 2022 - September: Invited Talk “The role of class-18 myosins in the assembly, organization and regulation of muscle stre

Structural and Functional Analysis of Disease Relevant Proteins Copyright: Nico Herzog Fotografie PD Dr. rer. nat. Susanne Eschenburg Institute for Biophysical Chemistry, OE4350 Hannover Medical Schoo

Methods Macromolecular X-ray crystallography State-of-the-art molecular biological and cell biological techniques Heterologous protein expression in prokaryotic and eukaryotic hosts Protein purificati

Methods Our group employs a combinatory approach of biochemistry, biophysics, TIRF imaging with purified proteins, genome editing and cell biology to better understand the molecular basis of a number

Teaching Bachelor of Science Biochemistry: Molecular Biochemistry and Methods (BCB P 15) Master of Science Biochemistry: Instrumental techniques (BCM WP 41) Human Medicine and Dentistry: Biochemistry/

Current Projects Analyses of actin-binding proteins in motility, phagocytosis and regulation of the cell cortex

Alumni Graduate Students Graduate Students Dr. Steve Ludbrook (1993-1996 PhD in the Eccleston and Manstein groups) Director Molecular Pharmacology, Bicycle Therapeutics, Cambridge, England, United Kin

Methods Methods Molecular and Cell Biology: mammalian cell cultures; human oocytes; primary neuronal and glial cells; D. discoideum ; immunohictochemistry; transfection Spectroscopy: Absorption and Fl

Research Interests Actin Myosin Dynamin Tropomyosin Cell motility and cytoskeletal dynamics Intracellular pathogen sensors Protein structure, dynamics, reaction mechanisms, and allostery Small-molecul

Scientific Achievements Total synthesis of FAD and FMN analogues and their application for probing stereo-specificities of flavin cofactors in enzymatic reactions. Pioneering work on the molecular gen