14.12.2021 Detecting lung cancer at an early stage: the HANSE Study, sponsored by the German Center for Lung Research (DZL) and the Lung Ambition Alliance, as the largest German early detection program [...] the ages of 55 and 79 years to attend a lung screening. Prerequisite: an elevated risk profile for lung cancer. Since then, over 600 people have been tested for lung cancer at the Hannover site. One of these [...] the symptoms for lung cancer. „I felt physically fit, there were no signs of lung cancer. However, after the HANSE CT examination, I learned that I already had an early stage of lung cancer“, says the

low-dose CT can detect lung tumours early and thus reduce lung cancer mortality. "With our HANSE Lung Check as a pilot study, we want to prove that a holistic and effective lung cancer screening programme [...] for participation. Registration for the free lung check is already possible online at www.hanse-lungencheck.de. Early lung cancer detection in Germany Lung cancer often causes no symptoms in its early [...] July, the largest German programme to date for the early detection of lung cancer starts with over 12,000 test persons. Three lung centres in northern Germany and the prominent doctor and patron of the

2021 For people with severe lung diseases, transplantation of a healthy organ is often the only chance of survival. But donor lungs are in short supply. A new artificial lung could provide relief. Since [...] an implantable lung". The aim is to develop an artificial lung that can be permanently implanted as an alternative to a donor organ. Hannover Medical School (MHH), Europe's largest lung transplant center [...] is working to combine lung and kidney support in a single device. "This so-called lung-kidney crosstalk is another aspect for the development of an individualized implantable lung," Dr. Wiegmann emphasizes

Pneumology, Allergology and Lung Transplantation in 2008. His clinical and scientific specialties include the diagnosis and therapy of rare lung scaffold diseases (interstitial lung diseases), the treatment [...] respiratory tract and lungs, and lung transplantation in children and adolescents. Dr. Schwerk was instrumental in establishing an international registry for children with interstitial lung diseases. The Hannover [...] certain diseases have been gained. In addition, controlled studies on the drug therapy of interstitial lung diseases were designed and conducted for the first time. These findings have been published in numerous

Lung transplantation for children and adolescents In the Clinic for Pediatric Pneumology, Allergology and Neonatology children and adolescents are cared for before and after lung and heart/lung transplantation [...] most common diseases leading to lung transplantation in childhood and adolescence are cystic fibrosis, pulmonary hypertension and various forms of childhood interstitial lung disease (ChILD). After successful [...] presentation before a possible transplantation takes place on an inpatient basis in our pediatric lung ward 63. At the Hannover Medical School, an average of eight to ten children from zero to 17 years

working group at the German Centre for Lung Research (DZL) at the BREATH Hannover site, will focus on interstitial lung diseases. This disparate group of different lung diseases affects tissue around the alveoli [...] many rheumatic diseases and after lung transplantation. The lung tissue becomes increasingly scarred and in many cases leads to pulmonary fibrosis, in which the lungs harden and no longer function properly [...] groups that only exist in diseased lung tissue, but not in healthy lungs. He now wants to use the new methods to find and test biomarkers for the early detection of lung diseases, the assessment of disease

was already described about 40 years ago as a cell type of its own in rat lungs. Whether such cells also exist in the human lung remained controversial in science. Now, a research team led by Professor [...] elasticity and stability of the lungs. Lipofibroblasts offer important therapeutic approaches However, myofibroblasts can also produce excessive amounts of collagen, hardening the lung tissue and thus triggering [...] important therapeutic approaches for the treatment of various lung diseases," explains the physician - but only if the findings from lung research on rodents can actually be applied to humans. Final proof

the lung expert. Especially at the beginning of COPD, the lung function is often not yet so severely damaged, so that the disease is then overlooked. "We have to look earlier, pay attention to lung health [...] of the 1960s." According to the lung expert, this is also due to the fact that COPD is a very comprehensive and multi-layered disease that encompasses a wide range of lung dysfunctions and can show itself [...] concomitant diseases. "In COPD lungs, we see different degrees of vascular remodelling, inflammation, mucus formation, and tissue destruction up to the overinflation of entire lung areas," the pulmonologist

Professor Tümmler. Therefore, most studies had only examined the microbiology of the lungs in acute infections or chronic lung diseases. "In our work, we collected cough swabs from healthy children aged three [...] high-performance computing technology. Healthy and sick children have the same lung microbiome at times The scientists found that the lung biome of healthy and sick children hardly differed from each other during [...] e and chronically settle in the lungs and the sensitive network breaks down. In healthy children, on the other hand, the network remains stable even though their lungs have a much higher bacterial load

gained a high expertise in complex endpoints for lung disease in cystic fibrosis, such as washout lung functions (MBW) and MRI examinations of the lung, which we perform in our clinical study center and [...] Inflammatory lung diseases in childhood Research focus Cystic fibrosis Cystic fibrosis (CF) is the most common monogenetically inherited inflammatory lung disease. About every 2000th newborn child in Germany [...] first line of defense against lung pathogens by producing pro-inflammatory cytokines in response to airway epithelial signals. We have recently shown that ILCs in human CF lungs produce the pro-inflammatory