Cancer Society (DKG). In addition to the treatment of soft tissue tumors, the center was also recognized for the treatment of bone tumors. The certificate attests that the center works according to current [...] therapy depending on the individual tumor situation," says Professor Dr. Mohamed Omar, medical director of the Sarcoma Center and division head of musculoskeletal tumor surgery at the MHH Department of Trauma [...] with the in-house molecular tumor board. The disease-specific range of treatments is supplemented by aftercare and supportive multiprofessional care services. Bone tumors: special implants using 3D technology

in the formation of a microenvironment conducive to tumor growth and are expressed not only on tumor cells but also on tumor-associated immune cells such as T cells, macrophages, and myeloid-derived suppressor [...] The Role of Purinergic Immune Regulation in the Peritoneal Tumor Microenvironment Purinergic signaling pathways, which include the ectonucleotidases ENTPD1 (CD39) and ENTPD3, are critically involved in [...] characterize the role of CD39 and ENTPD3 expressing immune cells in the context of metastasis of various tumor entities. Team PD Dr. med. Linda Feldbrügge Vincent Wolf Felix Gronau Prof. Dr. med. Beate Rau

markers for gastrointestinal tumor metastasis The diagnosis of metastatic tumors often requires invasive procedures such as biopsy, endoscopy, or diagnostic laparoscopy. However, tumors at different stages of [...] immune system in different ways. Therefore, the release of vesicles and second messengers into the tumor microenvironment may provide information about disease extent or entity through a simple blood draw [...] using microparticles and cell-free DNA. The goal is to improve the early detection of metastatic tumors in the gastrointestinal tract and to predict the success of therapy. Team PD Dr. med. Linda Feldbrügge

the invaders. Standard immunotherapies against tumors target the acquired immune system, which is weakened by the cancer. This is because although some tumors are teeming with immune cells, they do not attack [...] interested in the influence of fatty liver disease on the immune response in liver tumors and the role of ILCs in the immediate tumor environment. "The therapeutic potential of ILCs for immunotherapy is still [...] defense and how they communicate with cells of the acquired immune system in the HCC tumor. To do this, samples of human tumor tissue are compared with healthy liver tissue and analyzed to determine which immune

Molecular markers for gastrointestinal tumor metastasis Molecular markers for gastrointestinal tumor metastasis The Role of Purinergic Immune Regulation in the Peritoneal Tumor Microenvironment The Role of Purinergic [...] Purinergic Immune Regulation in the Peritoneal Tumor Microenvironment

to structures that are mainly located on the tumor cell, but not on the patient’s immune cells,” says Professor Schambach. Soften immunosuppression in tumor environment However, the CAR-NK cells have a [...] microenvironment softens the immunosuppressive effect in the area of the solid tumor, which further improves the destruction of the tumor cells,” explains Professor Schambach. If suitable candidates for the immune [...] are part of the first line of defense of our immune system. They eliminate virus-infested cells and tumor cells. This makes NK cells interesting helpers in cancer therapy. Professor Dr. Dr. Axel Schambach

Malignant tumors of the esophagus or stomach (e.g., esophageal and gastric carcinoma). Malignant tumors of the liver (e.g., hepatocellular or cholangiocellular carcinoma or metastases from other tumors) Benign [...] Benign and malignant tumors of the pancreas (e.g. pancreatic carcinoma) Benign and malignant tumors of the colon and rectum (e.g. ulcerative colitis, colon or rectal carcinoma) The robot does not replace

immediate reconstruction. Skin tumors Basal Cell Carcinoma Squamous cell carcinoma Melanoma Other malignant skin tumors Soft tissue tumors Lipoma Malignant soft tissue tumors, such as Liposarcoma Fibrosarcoma [...] Fibrosarcoma Locally aggressive tumors: Demoid, aggressive fibromatosis Palliative Surgery Peripheral nerve surgery Peripheral nerve surgery Peripheral Nerve Surgery at Hannover Medical School’s Department of

provide state-of-the-art treatment of malignant tumors, including advanced tumor stadiums with limited metastases, in an interdisciplinary manner coordinated in tumor boards. The 2022 annual report of the German

allows us to provide state-of-the-art treatment of malignant tumors and their metastases in an interdisciplinary coordinated manner in tumor boards. The annual report 2022 of the German Cancer Society (DKG) [...] complex. As the largest transplant center in Germany, we also examine alternatives to resection in tumor boards, e.g. the option of liver transplantation. An individually tailored surgical preparation and