approach is the direct transfer or repair of the gene affected by a mutation. Numerous clinical studies are currently investigating the transfer of "healthy" genes using viral vectors that are taken up [...] then be repaired by homologous recombination with a "healthy" DNA sequence. A recently published study demonstrated the correction of the rare metabolic disease tyrosinemia in experimental animals by injecting [...] understand the molecular complexities of liver cancer development, progression, and regression. They study how small non-coding RNAs such as microRNAs affect genes and cancer metabolism during liver tumor

Project Requests Concerning project requests and questions about: Study support Sample storage Sample processing DNA isolation of biospecimen please contact: Prof. Dr. Thomas Illig Scientific Head of HUB

German) Trial contact form (in German) Contact information: Telephone registration for patients: Study Phone: 0511 532 5086 Registration only by medical practices or in case of medical queries: Phone:

Annual Meeting 2025. With her poster ‘Organotypic in vitro model of the human lung using hiPSCs to study epithelial-macrophage interactions and bacterial infections in the microenvironment of the upper

International Master study programme "Infectious Diseases - One Health (IDOH)" Module: Infectious Diseases and Diagnostics Module coordinators: Prof. Dr. Abel Viejo-Borbolla, Dr. Nishanth Gopala Krishna

https://www.fli.de/en/home/ Living in Germany DAAD http://www.daad.de/deutschland/en/ Studying in Germany http://www.studying-in-germany.org/phd-in-germany/ Make it in Germany (how to make a career in Germany

cGAS/OAS innate immune sensors using time-resolved serial crystallography and high-pressure synchrotron studies In this project, the kinetic states and conformational changes associated with substrate binding [...] methodologies: time-resolved serial femtosecond crystallography, on-chip substrate or product binding studies, and high-pressure crystallography. The obtained mechanistic information will be used to develop

the dermatology-allergology laboratory Medical quality management representative PI in clinical studies Contact E-mail Phone: 0511 532-0 Fax: 0511 532-161013 Qualifications Specialist in dermatology and [...] in allergology (12 months, Lower Saxony Medical Association) Principal Investigator in clinical studies Clinical and scientific focus All forms of urticaria and angioedema, hereditary angioedema, drug

create a scientific infrastructure dedicated to the generation of in vivo systems enabling infection studies and long-term antiviral drug evaluation. Thus, the unit recently has merged with the Humanized Mouse [...] UKE to serve as a new competitive technological platform enabling in vitro and in vivo infection studies with human hepatotropic viruses and preclinical evaluation of new therapeutic concepts within the

limited efficacy in only a subset of patients. The role of the immune system in HDV infection has been studied incompletely. We have been able to map CD8+ T-cell epitopes in chronic HDV infection and characterize [...] while T cells with viral eliminating capacities are chronically activated and prone to apoptosis. By studying immune responses in the liver we could demonstrate that the phenotype of CD8+ T cells is influenced