single-cell analysis, and on the other hand, the analysis of complex metagenomes based on different human tissues and body fluids using optimized laboratory processes and an analysis pipeline developed in-house

huge impact for both the optimization of differentiation protocols as well as for drug-screening are human iPS reporter cell lines which are generated using TALEN-based homologues recombination ( RG Martin

Theresia Kraft, Molecular and Cellular Physiology, OE 4210, project: Cardiomyocytes derived from human induced pluripotent stem cells as an in vitro model for Familial Hypertrophic Cardiomyopathy Natalie

Forensics and Genetics Center for Pathology, Forensics and Genetics Institute of Pathology Institute of Human Genetics Institute of Legal Medicine Center for Pharmacology and Toxicology Center for Pharmacology

Shaheed IB, Mosimann C, Diecke S, Schmidt-Ott KM . The centrosomal protein 83 (CEP83) regulates human pluripotent stem cell differentiation toward the kidney lineage. Elife, 11:e80165, 2022. Hinze C, [...] Rajewsky N, Schmidt-Ott KM . Single-cell transcriptomics reveals common epithelial response patterns in human acute kidney injury. Genome Medicine, 14:103, 2022. Hinze C, Karaiskos N, Boltengagen A, Walentin

011-0205-9. Epub 2011 Jul 19. PMID: 21769673 Quantification of Mutant versus Wild-Type Myosin in Human Muscle Biopsies Using Nano-LC/ESI-MS, Edgar Becker , Francisco Navarro-López, Antonio Francino, Bernhard

complications caused by herpesviruses such as cytomegalovirus (CMV), Epstein-Barr virus (EBV) and human herpesvirus (HHV)-6 as well as by lytic viruses such as adenovirus (ADV) are the most common causes

Roeles, J. and Tsiavaliaris, G. (2019). Actin-microtubule interplay coordinates spindle assembly in human oocytes. Nat. Comm. 10:4651. https://doi.org/10.1038/s41467-019-12674-9 . Transformation of the n [...] gene mutation confers diabetogenic susceptibility in the LEW.1AR1/Ztm-iddm rat, an animal model of human type 1 diabetes. Arndt, T., Wedekind, D., Jörns, A., Tsiavaliaris, G., Cuppen, E., Hedrich, H.-J. [...] 2536-2541. DOI: https://10.1073/pnas.1316390111 Inactivation of hepatitis C virus infectivity by human breast milk. Pfaender, S., Heyden, J., Friesland, M., Ciesek, S., Ejaz, A., Steinmann, J., Steinmann

Ethics and Philosophy of Medicine, Hannover Medical School 2012-2017: Doctorate (German Institute of Human Nutrition / KU Leuven) Dissertation: "Decision to participate in cohort studies with biobanks: an

disease models Final exam November 2005 Krishna Kumar Singh INDIA supervisor: Prof. Dr. Schmidtke, Human Genetics, OE 6300, project: Disease related variants of ARMD and functional implications Final exam