brain abnormalities in humans. We found that stress induces muscle degeneration even in wild type animals and accelerates age-dependent muscular dystrophy and that miRNAs are involved in this process. Future
students). Heads the research commission of the MHH (FoKo) Heads the MHH advisory board for the central animal facility, currently represented by Prof. Dr. Reinhold Förster. Cooperation with the Ombudsperson
PhD students are fully financed for 3-4 years. Courses available outside the curriculum include: Animal Handling Gene Technology Omics and Bioinformatics Good Scientific Practise Master Class Lectures
ce in-situ hybridization (FISH) in the diagnosis of hematological diseases Animal experimental methods (introduction) Animal experimental methods (specific courses) 2.2 Special Seminars: Molecular biological [...] as ‘Presentation techniques', ‘Scientific writing', ‘Research ethics', ‘Gene technology safety', ‘Animal experiments' as well as career perspectives. Excursions to industry also take place regularly. See [...] institutes to provide up-to-date technologies and support (e. g. gene expression profiling, experimental animal work, confocal microscopy for in vivo imaging, and proteomics). A huge library with relevant textbooks
transporter – in experimental colitis Supervisor: Prof. André Bleich, PhD, Institute for Laboratory Animal Science, MHH Academic Background: Biotechnology Medical Specialty, University of Pécs, Medical School [...] soluble CD14 in mouse colitis models Supervisor: Prof. André Bleich, PhD, Institute for Laboratory Animal Science, MHH Academic Background: Veterinary Medicine, TiHo Mareike Schubert Research Topic: Mechanisms
investigation of subcellular GCPR signaling in cell culture, organotypic environment and in living animals Characterization of specific G-proteins and downstream effectors involved in GPCR-mediated signal [...] allows functional studies in primary culture, organotypic and acute slices as well as in living animals. PI: Dr. F.E. Müller , Dr. A. Zeug Recent publications: Induced Remodelling of Astrocytes In Vitro
Institute ITEM Project: Mechanisms to prevent RSV-mediated Asthma onset and exacerbations Manfred Anim GHANA anim.manfred @ mh-hannover.de Supervisors: Dr. F. Atschekzei / Prof. Dr. reihold e. Schmidt, Department
significance and better establishment of organotypic in vitro systems, which are alternatives to animal testing based on the 3R principle (Replace, Reduce, Refine), in inhalation toxicology. Before moving
organisms with a fully known microbial status including germ-free animals, which are devoid of all living microorganisms, and animals colonized with specific microbial species. The insights gained from [...] Multiple diseases have been associated with shifts in microbial composition and function. Gnotobiotic animals are valuable experimental model to investigate the function and the role of the intestinal microbiota [...] ranges of diseases and health conditions. To ensure their strict microbiological status, gnotobiotic animals are housed in specialized equipment such as isolators. The Gnotobiotic unit is a state-of-the-art
710-990 nm Transmitted light imaging DIC, phase contrast Imaging a different sample sizes From animals, organs, tissues to cells and molecules Live cell imaging Temperature, humidity, and CO2 regulation