consist of more than 20 different cell types. Disorders of embryonic development of the kidney due to genetic or environmental factors lead to congenital defects of the kidney and the urinary tract, arterial [...] for repair, this regenerative potential is significantly impaired in aging and in individuals with genetic or developmental predisposition or comorbidities such as diabetes or hypertension. The situation [...] targeted therapies. Our group investigates the molecular and cellular basis of developmental and genetic injury susceptibility, injury response and repair of epithelial cells within the kidney and allograft

research focuses on advanced lung organoids, which are three-dimensional microtissue models derived from human induced pluripotent stem cells (hiPSC) that replicate the properties of the lower airways in vitro [...] pollutants and beyond. The disease-relevant signatures in the lung will also be correlated with genetic predisposition, biological sex, and epigenetic regulation. These patient-specific, hiPSC-derived

cardiac support system. With the help of induced pluripotent stem cells (iPS cells) from genetically reprogrammed human tissue cells, heart muscle cells can be produced. These should form the basic building

Conventional Imaging Nuclear imaging CT/MRI-guided biopsy procedures Pathological diagnostics Human genetic diagnostics Surgical therapy Resecting procedures (musculoskeletal, visceral and thoracic sarcomas

subgroups are mostly diseases whose genetic basis is not yet known. For this reason, future patient groups with a significant number of cases will be examineded for common genetic alterations. Accurate phenotyping [...] results a continuation of the project is planned involving further internal and external research institutions. On the basis of the results of the retrospective study previously published, various subgroups

2014 – January 2020: PostDoc at the Institute for Clinical Biochemistry (formerly Institute for Cellular Chemistry), MHH June 2010 – July 2014: PhD at the Institute for Clinical Biochemistry Doktorarbeit [...] on the (Glyco-) Proteome of Human Pluripotent Stem Cells“ 2010: diploma thesis at the Diplomarbeit Institute for Clinical Biochemistry, MHH in cooperation with the Institute of Microbiology, University [...] g-Str.1 building J03, floor 03, room 1330 Curriculum Vitae Since December 2021: PostDoc at the Institute for Molecular and Cell Physiology, Hannover Medical School (MHH), Hannover, Germany February 2020

anti-infectives. Microbial metagenome of the respiratory tract The Human Microbiome Project has characterized the microbiome of healthy humans in numerous organs, but has left out the lower respiratory tract [...] use p.Phe508del homozygous CF patients as an example to test which environmental factors and which genetic factors outside the causally affected gene modulate the severity of the clinical picture in a congenital [...] Pseudomonas aeruginosa lives in soil, fresh and salt water and colonizes plant and animal surfaces. In humans, P. aeruginosa has become one of the most common bacterial pathogens of local infections of the eye

leader “Synaptic plasticity” at the Institute for Neuroanatomy and Cell Biology at the MHH (Head: Prof. Dr. med. M. Lenz) 2016 - 2023 Academic Councilor at the Institute for Neuroanatomy and Cell Biology [...] (Head: Prof.in Dr. rer. nat. C. Grothe) 1998 – 2016 Research Associate / Academic Councilor at the Institute for Cell Biology in the Center for Anatomy at the MHH (headed by Prof. Dr. rer. nat. E. Ungewickell) [...] substances with activities up to 105 times the exemption limit 1998 Expertise for project managers of genetic engineering work and representatives for biological safety Since 1998 Appointed examiner in the subject

Analysis of connexin 43, connexin 45 and N-cadherin in the human sertoli cell line FS1 and the human seminoma-like cell line TCam-2 in comparison with human testicular biopsies. Schulz B., Schumacher V., Ngezahayo [...] Advanced Tissue Culture Models at the Institute of Neuroanatomy and Cell Biology, Hannover Medical School 2019-2024 Research scientist/postdoctoral fellow at the Institute of Cell Biology and Biophysics, Department [...] hD candidate at the Institute of Cell Biology and Biophysics, Department of Biophysics, Gottfried Wilhelm Leibniz University Hannover 2012-2014 Research Assistant at the Institute of Cell Biology and

biological heart support system. So-called induced pluripotent stem cells (iPS cells) from genetically reprogrammed human tissue cells can be used to produce heart muscle cells. These will now form the basic