expression in single cardiomyocytes from cryosections of HCM patients and heart-healthy controls and in human induced pluripotent stem cells. We could show that individual cardiomyocytes express highly divergent [...] Montag J., Weber N., Kowalski K. , Mayer A.-K., Iorga B., Brunkhorst A., Zweigerdt R., Kraft T., Human pluripotent stem cell-derived cardiomyocytes mimic intercellular heterogeneity as pathomechanism in [...] Thiemann S., Schwanke K., Lingk A., Krumm U., Piep B., Martin U., Zweigerdt R., Brenner B., Kraft T., In human embryonic stem cell-derived cardiomyocytes twitsch kinetics, action potential parameters and MyH-mRNA

semester, Modul BCM P 04) Lab internships and Master thesis (scheduled individually) Medicine („Human- und Zahnmedizin“): Seminars in Biochemistry /Molecular Biology („Nukleinsäuren 1&2“) Practical course

Thum (IMTTS and Fraunhofer ITEM) Project: Investigating cardiac diseases in miniaturized LMS from human cardiac samples Marco is class speaker! Katja Bezjak SLOVENIA Bezjak.Katja @ mh-hannover.de Supervisor: [...] erology/ Hepatology/ Endocrinology and Twincore) Project: Identification and characterization of human monoclonal antibodies neutralizing Hepatitis E Virus Eline Gall GERMANY Gall.Eline @ mh-hannover.de [...] ogy) Project: Defining the nutritional components and factors that exacerbate steatohepatitis in human hepatocytes with PNPLA3-148M Chiara Malinconico ITALY Malinconico.Chiara @ mh-hannover.de Supervisor:

Frontiers ► Research Gate Differential impact of substrates on myosin heavy and light chain expression in human stem cell-derived cardiomyocytes at single-cell level, Felix Osten, Alea K Bodenschatz, Karina Ivaskevica [...] abstract available., PMID: 29992791, PubMed Differences in Contractile Function of Myofibrils within Human Embryonic Stem Cell-Derived Cardiomyocytes vs. Adult Ventricular Myofibrils Are Related to Distinct [...] PMID: 29403388, PubMed Stiff matrix induces switch to pure β-cardiac myosin heavy chain expression in human ESC-derived cardiomyocytes., Weber N, Schwanke K, Greten S, Wendland M, Iorga B, Fischer M, Geers-Knörr

organoid for the first time. Robert Zweigerdt, Miriana Dardano, Lika Drakhlis (from left) How do human organs develop and what happens to them when they become diseased? To answer these questions, researchers [...] therapy for regenerating damaged hearts. HEAL Project Page TACTiC Preclinical evaluation in a non-human primate model and a roadmap for clinical application The Federal Ministry of Education and Research [...] system. With the help of induced pluripotent stem cells (iPS cells) from genetically reprogrammed human tissue cells, heart muscle cells can be produced. These should form the basic building block for a

Gruh research group took place on June 6th. Sara successfully defended her dissertation titled ' Human induced pluripotent stem cell-based 3D engineered tissue models of cardiac fibrosis' . We wish Sara

animals to humans and have caused two epidemics including the current COVID-19 pandemic. The treatment options against these viruses are very limited. The ways corona viruses are transmitted to humans as well [...] status in addition to results from serology testing for antibodies against SARS-CoV-2. Development of human neutralizing monoclonal antibodies against SARS-CoV-2 Project leader: Prof. Dr. med. Thomas F. Schulz [...] Department / Institute: Institute of Virology We want to generate broadly neutralizing, i.e. protective, human monoclonal antibodies as recombinant proteins for a future antiviral treatment in the early phases

Cluster of Excellence REBIRTH. In the LEBAO, represented by Prof. Ulrich Martin and Dr. Ina Gruh, human stem cell derived cardiac muscle cells were presented.

Your career with us Scientific programs The clinic regularly offers doctoral programs for human or dental medicine graduates as well as for natural science graduates. After completion of the doctorate

Toxicology and Experimental Medicine ( ITEM ), Hannover Project: Air-Liquid Interface cultures of human primary distal respiratory epithelial for in vitro modelling of SARS-CoV2 infections To investigate [...] project we will first establish methods for isolating and expanding distal epithelial cells from human lung explants and differentiate these into AT1 cells in air-liquid interface cultures that can serve