for his research on human macrophages in the amount of 1.5 million euros over five years. Human immune cells - produced in the laboratory Professor Lachmann's method is based on human cells of the immune [...] adequately reflect human physiology in some cases and because the European authorities will no longer accept them from 2026. The MAT based on donated blood cells better reflects human physiology, but is [...] down to the smallest detail. RESIST consists of six partner institutions. The spokesperson is Professor Dr Thomas Schulz, head of the MHH Institute of Virology. RESIST is funded by the German Research Foundation

mellitus, and even to scarring of the liver tissue (liver cirrhosis) and liver cancer. The cause is a genetic defect that disrupts the regulation of iron absorption via the mucous membrane of the small intestine [...] injection, the rate of gene correction was twelve percent. "This is a great success, because most genetic diseases can already be controlled if five percent of the cells have the correct gene," emphasises [...] to 30 to 40 per cent," Dr. Krooss hopes. If this succeeds and the application then also works in humans, a single injection could in future save people suffering severely from haemochromatosis from liver

mouse model, for example, Dr Saborowski is researching the influence of certain genetic modifications on a tumour. Is the genetic modification suitable as a target structure for drug therapy approaches? Can [...] Medical Centre Mainz for almost 20 years - under his aegis it became an internationally leading institution for the treatment of malignant blood and tumour diseases and a centre for stem cell transplantation [...] international research funding organisations and as a scientific advisor in major German research institutions such as the German Cancer Research Center in Heidelberg, the GSF Research Center for Environment

women between 25 and 35 years of age. The main risk factor for developing cervical cancer is the human papillomavirus (HPV). Surgery is the treatment of choice. However, such an operation is problematic [...] colloquially known as "tumour suppressor genes". Methylation acts like a cap that sits on top of the genetic material and blocks the gene. The HP virus thus has an easy game and can drive cancer development

vectors are often used as gene shuttles because they do not cause any diseases themselves and their genetic material is rarely incorporated non-specifically into the genome of the host cell. However, because [...] much smaller than 100 nanometres, i.e. smaller than 100 millionths of a millimetre. By comparison, a human hair is about 70,000 nanometres thick. The tiny particles are easily absorbed into body cells, making

two female dentists, eleven male and three female natural scientists, four male and three female human biologists, and two female doctoral students in population medicine (public health). A total of 17 [...] Mycobacterial Disease (MSMD) Liart Pollmann, MD, PhD , has completed his doctoral thesis entitled "Human Lentiviral Gene Therapy Restores the Cellular Phenotype of Autosomal Recessive CompleteIFN-γR1 Deficiency" [...] ferries. In doing so, he successfully demonstrated the correction of the IFN-γR1 signaling protein in human target cells. In addition to mycobacteria causing tuberculosis, so-called non-tuberculous mycobacteria

well-educated engineers, scientists, and clinicians To advance regenerative medicine to repair the human body following injury or disease, there is a critical need for well-educated engineers, scientists [...] , and clinicians to work jointly to translate applied research to clinical treatments to improve human health. “MHH has built a unique environment to bring all these facets together. In particular knowledge [...] Artificial Organs (LEBAO) , the Clinic for Pediatric Pneumology, Allergology and Neonatology , and the Institute of Quantum Optics (Leibniz University) at the NIFE are at the forefront in this research area. By

explains Professor Dr. Britta Eiz-Vesper, immunologist at the MHH Institute for Transfusion Medicine and Transplant Engineering. As the institute is not only one of Germany's leading manufacturing sites for [...] Neurophysiology, the Institute of Transfusion Medicine and Transplant Engineering, the Department of Paediatric Haematology and Oncology, the Department of Pneumology and the Institute of Diagnostic and [...] all people worldwide without most of them even noticing it. But once it has entered the body, the genetic material of the pathogen remains dormant. If the immune system is weakened or shut down by a serious

biological heart support system. So-called induced pluripotent stem cells (iPS cells) from genetically reprogrammed human tissue cells are used to produce heart muscle cells and blood vessel-lining endothelial [...] emphasises. Later clinical studies will then show whether the heart prosthesis from the MHH also works in humans. Who does what? For the 3D Heart 2B project, an interdisciplinary team from the fields of biology

severe diseases such as meningitis and blood poisoning in young children. Researchers from the MHH Institute of Clinical Biochemistry have deciphered the pathway of the bacterial capsule and thus created the [...] Hib vaccine inexpensive and safe. The bacterium Haemophilus influenzae type b (Hib) inhabits the human nasal cavity. It causes infections of the upper and lower respiratory tract, especially in infants [...] polymers, the bacterium protects itself against the host's immune system and can thus survive in the human body. Vaccines against Hib are available, which contain the sugar polymers in the capsule and train