elucidation of the molecular mechanisms of proteins whose function is vital for the health of the human organism. Combining leading techniques for structure determination with state-of-the-art cell biological

establish an ex vivo organ-/immune-system interface simulating immune responses after engraftment of human donor livers. Precision-cut slices of donor livers performed prior engraftment serve as a three-d

Project leader: Prof. Dr. Danny D Jonigk, FRCPath Department / Institute: Institute of Pathology Human Non neoplastic interstitial lung diseases are complex, ill understood and consist of >120 defined [...] rypsin (A1AT) is an acute-phase glycoprotein and one of the most abundant protease inhibitors in humans. A1AT is also characterized as a protein with broad immunomodulatory and immunosuppressive capacities

The aorta is the largest blood vessel in the human body. It originates in the heart and carries oxygen-rich blood to all parts of the body. The most common disease of the aorta that requires treatment [...] by it reflexively. The silk is extremely thin and tear-resistant and completely degradable in the human body. Using a special apparatus that assistant physician Dr Helms constructed himself, the thread

"We have successfully tested the efficacy of our RNAi candidates on human lung tissue sections as well as in 3D cell cultures from human lung epithelium," explains Professor Dr. Armin Braun, Head of Preclinical

treated for six months a total of five times with mesenchymal stem cell products obtained from a human umbilical cord. "The treatment led to a significant improvement in growth, exercise tolerance and [...] stem cell therapy is based on cells from the umbilical cord of newborns and is also called HUCMSC (human umbilical cord mesenchymal stem cell). The researchers' analyses showed that the products of these

Korf-Klingebiel, biologist and first author of the study. Whether all of this is also significant for humans was investigated by the team in patients with heart failure due to aortic stenosis. In this disease [...] laboratory, the MYGDF level dropped to normal. Pressure overload thus also leads to MYDGF release in humans. The work shows that the positive aspects of inflammation must be considered when thinking about

infection of iPSC-derived human peripheral neurons available in the laboratory. The two main objectives of this project are: (i) To investigate SARS-CoV-2 replication and transport in human peripheral neurons [...] gram-negative pathogens in hospital settings iNeuronS / Infection, transport and degeneration of human neurons caused by severe acute respiratory syndrome coronavirus 2 Project leader: Prof. Dr. Abel

Application for a place to study at 1st semester in human medicine or dentistry International applicants Copyright: Gordon Johnson/Pixabay Applicants from non-EU countries must apply via the agency uni-assist [...] 01 . for the Studienkolleg in the summer term (Please, choose the degree programm "Studienkolleg Human-, Zahnmedizin und Hebammenwissenschaft) You can check here whether you can study directly in Germany [...] in the respective federal state. In order to be able to apply for a place to study at the MHH in Human Medicine or Dentistry after successful completion of the Studienkolleg, you must attend the so-called

cells in neonates and further characterize this newly described innate-like T cell population in humans.