Translational Vectorology Research Unit (TVRU), and to establish and manage the Vector and Genome Engineering Facility (VGEF). His research concentrates on the studies of AAV biology and vectorology, and [...] a number of gene therapy programs that aim to develop novel advanced therapeutics for paediatric genetic disorders affecting the CNS, lungs, liver and other organs.

Biotechnology and Genetic Engineering, Islamic University Kushtia, Bangladesh Sultan Ahmed Research Topic: Role and signature of naturally occurring, adoptively transferred and genetically modified herpe [...] recipients Supervisor: Prof. Dr. Britta Eiz-Vesper, Institute of Transfusion Medicine and Transplant Engineering, MHH Academic Background: Biotechnology, University of Hyderabad, India Vicente Almeida Research

by Professor Dr Rainer Blasczyk, head of the Institute for Transfusion Medicine and Transplant Engineering at the Medical School (MHH), wants to solve this problem. The aim is to use molecular biological [...] research team produces them in cell culture from induced pluripotent stem cells (IPSC). These are genetically reprogrammed body cells that have similar properties to embryonic stem cells, i.e. they can develop [...] Figueiredo, senior scientist at the Institute and deputy project leader. In addition, the scientist genetically modified the iPSC and also switched off the HLA characteristics of the cells. The result is a kind

so-called "gene editing" for the targeted genetic modification of cells, scalable bioreactor systems for stem cell expansion and differentiation, or tissue engineering for production of cardiovascular tissue [...] r Implants (Medimplant), Leibniz Universität Hannover, the Lower Saxony Center for Biomedical Engineering, Implant Research and Development (NIFE), Fraunhofer ITEM, the German Primate Center, corlife oHG

experiments with special requirements regarding (a) biological safety (infectious samples, genetic engineered organisms of biosafety level S2) or (b) complexity of the staining (multicolor experiments [...] intended for cell sorting with special requirements regarding (a) biosafety (infectious samples, genetically modified organisms of biosafety level S2) or (b) complexity of the staining (multicolor experiments

Reimann , GERMANY, Reimann.Pia @ mh-hannover.de Supervisor: Prof. Dr. med. Nataliya Di Donato (Human Genetics) Project: The clinical relevance of copy number variation and transcriptional dysregulation of actin [...] mh-hannover.de Supervisor: Prof. Dr. rer. nat. Britta Eiz-Vesper (Transfusion Medicine and Transplant Engineering) Project: Exploiting Glycosylated Tumor Antigens for CAR-T-Cell Therapy in Hematological and Solid [...] stud.mh-hannover.de Supervisor: PD Dr. Georgios Sogkas (Rheumatology and Immunology) Project: Novel genetic causes of immunodeficiency and immune dysregulation Maja Stankewitz , GERMANY, Stankewitz.Maja @

various diseases. 3. Genetic modification of iPS cells and iPS cell-derived cell types Many cardiovascular diseases, e.g. of the heart or the respiratory tract, are associated with genetic defects or mutations [...] which patient-specific cells are obtained, reprogrammed into iPS cells , and then genetically corrected . So far, genetic modifications of stem cells have primarily been performed using randomly integrating [...] system. These enzymes can be engineered to insert a DNA double/single-strand break in a specific locus, allowing for the targeted modification of the genome and correction of genetic defects with the help of

reprogram the replication machinery of the virus so that the virus only replicates in cells that exhibit genetic changes characteristic of tumors, such as p53 dysfunction or telomerase activation. We have already [...] approach. Research projects Generation of conditionally replicating (oncolytic) adenoviruses through genetic modification Development of in-situ vaccination concepts through the use of cytokine-armed oncolytic [...] oncolytic viruses Understanding the induction of antitumor immune responses by oncolytic virotherapy Genetic modification of adenovirus capsid proteins for improved infection of tumors Development of predictive

online lecture) ‘Genetic engineering of organs to support graft survival after transplantation’ Prof. Dr. Constanca Figueiredo, Institute of Transfusion Medicine and Transplant Engineering, MHH ‘Of drugs [...] learned from lung fibrosis’ Dr. Jonas Christian Schupp, Clinic of Pneumology and Infectiology, MHH ´Genetic skewing of macrophage function to enhance the therapeutic properties’ Schifaa Abdin (Group of Prof [...] on, MHH: ‘Rebirth of translational immune oncology for leukemias and lymphomas: from the cell engineering, disease models and GMP towards the patients’ 15.12.2021 REBIRTH Kolloquium (1 pm s.t., online

Bettina Wiegmann, who heads three of the four MHH projects at the Lower Saxony Center for Biomedical Engineering, Implant Research and Development (NIFE). The scientist hopes to prevent this thrombus formation [...] g endothelial cells. "These endothelial cells, which are not endogenous to the body, are also genetically modified so that they are virtually invisible to the patient's immune system and are therefore [...] Dr. Constanca Ferreira de Figueiredo from the Institute of Transfusion Medicine and Transplant Engineering. A fourth is based at the Leibniz Research Laboratories for Biotechnology and Artificial Organs