advanced protocol for the generation of heart-forming organoids from human pluripotent stem cells Heart-forming organoids (HFOs) derived from human pluripotent stem cells are a complex, highly structured in vitro [...] vitro model of early heart, foregut and vasculature development. In the human embryo, these tissues emerge in close proximity to each other and rely on signal exchange for proper development. HFOs represent

specialist in laboratory medicine, together with Marie she is also working on better characterization of human immune cells. Nils Funk Funk.Nils @ mh-hannover.de MD Student Nils is an MD student who is working [...] senescence. Andreas Penndorf andreas.penndorf @ stud.uni-hannover.de MSc Student Andreas studies human natural killer cell immunity in close collaboration with the central laboratory of Hannover Medical [...] stud.mh-hannover.de MD Student Marie is an MD student who is working on better characterization of human immune cells.

Analysis of connexin 43, connexin 45 and N-cadherin in the human sertoli cell line FS1 and the human seminoma-like cell line TCam-2 in comparison with human testicular biopsies. Schulz B., Schumacher V., Ngezahayo [...] Cell Dev. Biol., Volume 8 – 2020, DOI: 10.3389/fcell.2020.00869. Concatenation of human connexin26 (hCx26) and human connexin46 (hCx46) for the analysis of heteromeric gap junction hemichannels and h [...] Advanced Tissue Culture Models : Biomimetic 3D models of neurodegenerative diseases Development of humanized and animal-free models in order to investigate new therapeutics for neurodegenerative diseases

onal human pluripotent stem cell-derived cardiomyocyte models for investigating cardiac hypertrophy” Wiebke Triebert (RG Zweigerdt): “Bioprocess development for GMP-compliant production of human pluripotent [...] cell-derived cardiomyocytes” Kevin Ullmann (RG Zweigerdt): “Physical and Physiological Control of Human Pluripotent Stem Cells Culture” Mark-Christian Jaboreck (RG Martin): “Development of a hiPSC-based

05/04/2023 The Department of Human Genetics of Hannover Medical School (MHH) has a new director: Professor Dr. Nataliya Di Donato took over the management of Professor Dr. Brigitte Schlegelberger at the [...] the beginning of the month. The 43-year-old specialist in human genetics previously worked as deputy director of the Institute of Clinical Genetics at the University Hospital of the Technical University [...] University of Dresden. "We are pleased that we were able to win such a proven human geneticist for this management task and to strengthen our priorities," emphasizes MHH President Professor Dr. Michael Manns. "We

Archive HEAL Project Graduation 2023 Winter TACTiC Project Graduation 2022 Summer Generation of human induced pluripotent stem cell lines - Encoding for genetically encoded calcium indicators RCaMP1h and [...] organoids - New publication on a detailed protocol for the production of heart-forming organoids from human pluripotent stem cells Teaching Award of the Student Body 2021 - Outstanding Commitment in Teaching [...] research group can replicate early heart development in the cell culture dish for the first time using human stem cells Scalable Process for Differentiation of Pluripotent Stem Cells into Definitive Endoderm

Infektiologie und Endokrinologie ‘Generation of multicellular human liver microtissue models using organoid-derived and direct reprogrammed human hepatocyte-like cells’ Fawaz Ahmad Saleh from the Department [...] Biotechnology & Artificial Organs (LEBAO) ‘Establishing a scalable bioreactor platform to generate human iPSC-derived hematopoietic cell types for regenerative applications’ Ana-Maria Zamfirescu from the

composition of sarcomeric proteins. Subcellular myofibrils can be obtained from human (e.g., biopsies), human-derived and non-human cardiac and skeletal small muscle samples (e.g., mouse, rat, rabbit, zebrafish [...] maturation of human pluripotent stem cell-derived cardiomyocytes; (2) Understanding the effects of missense mutations in sarcomeric proteins on the subcellular and cellular contractile function in human cardiac [...] School; Research topics: Force-related kinetic studies with subcellular myofibrils using human myocardial samples and human embryonic/induced pluripotent stem cell-derived cardiomyocytes. 2011-2013 : Junior

MZP Cardiomyocytes from human induced pluripotent stem cells as a cellular model for hypertrophic cardiomyopathy Researc h focus The focus of our research is the analysis of human induced pluripotent stem [...] β-Myosin heavy chain isoform-expressing myofibrils within human ESC-derived cardiomyocytes recapitulate the contractile features of adult human ventricular myofibrils?, J. Muscle Res. Cell. Motil., 2017 [...] Martin U, Zweigerdt R, Kraft T , Brenner B. Differences in Contractile Function of Myofibrils within Human Embryonic Stem Cell-Derived Cardiomyocytes vs. Adult Ventricular Myofibrils Are Related to Distinct

is a lack of nationwide access to human genetic care, especially in rural areas.The innovation fund project "OnkoRiskNET", led by a team from the MHH Institute of Human Genetics, has tackled this problem [...] Director of the Institute of Human Genetics until May 2023, adds: "We see that cancer patients in this stressful situation often cannot find the long way to an institute of human genetics. It was therefore [...] cancer and can lead to the development of tumors," says Professor Dr. Anke Bergmann, specialist in human genetics and head of the OnkoRiskNET project. "With this project, we want to ensure access to genetic