patients with progressive myocardial insufficiency because of myocardial infarction. In previous studies, the cells were injected manually into the recipient heart. In order to allow an optimized and b [...] the preclinical implementation of new cell therapy concepts, a review of the data from in vitro studies in the living organism is inevitable. Only suitable animal models allow such therapeutic applications [...] knowledge, preclinical testing of our therapeutic concept is only possible in non-human primates. Our studies in rhesus monkeys will be performed at the German Primate Center in Göttingen according to strict
(SC)-based approaches have been proposed for heart repair, but a multitude of experimental and clinical studies applying various adult stem cells have not achieved functional improvement, or showed only minor [...] implant-related arrhythmias could be controlled through technical pacemaker devices. A promising study (published in 2014) demonstrated, for the first time, the formation and functional coupling of large [...] Old Word monkeys and are frequently used in pharmaceutical industry, e.g. for safety and efficacy studies for certain drug approval. Preclinical assessment of our cell therapy concept is crucial to cover
fellows in the nextGENERATION program Agnes Bonifacius (Dr. rer. nat.) Year 2023 Dr. Agnes Bonifacius studied human biology (Bachelor of Science, Master of Science) at the University of Greifswald. She then
Chief of the Department of Nephrology and Hypertension at Hannover Medical School. Kai Schmidt-Ott studied medicine in Berlin and New York. He began his clinical training in 2001, performing his medical residency
for anti-inflammatory therapies as well as targets for preventive measures for these diseases. By studying in vitro models, mouse models, and patient material we identify and characterize the immunologi
survival time of patients with newly diagnosed AML. This was the result of an international clinical study with the participation of Professor Dr. Michael Heuser, Senior Physician at the Department of Haematology
also possible. How common is an allergy? Allergies have been known since ancient times. Various studies from England show that the incidence of allergies has been steadily increasing, especially in recent
reasons for this and the strategies that can be used to overcome resistance to molecular treatment. The study has been published in the renowned journal "Hepatology". The first author is PhD student Gajanan Kendre
sustainably. We develop knowledge in exchange with the best This means for us In patient care, clinical studies and in research and teaching, we work together with the best in their field. To do this, we network
Analytik. Tierärztliche Hochschule Hannover (TiHo) „Use of Trichoplax adhaerens as model system for studying transcriptional regulation and principles of cytoskeleton function in Metazoa” Prof. Dr. Bernd