Brinkert, S. Hedtfeld, A. Burhop, R. Gastmeier, P. Gad, D. Wedekind, C. Kloth, J. Rothschuh, N. Lachmann, M. Hetzel, A. Chari Jirmo, E. Lopez-Rodriguez, C. Brandenberger, G. Hansen, A. Schambach, M. Ackermann [...] S. Guan, A. Munder, S. Hedtfeld, P. Braubach, S. Glage, L. Zhang, S. Lienenklaus, A. Schultze, G. Hasenpusch, W. Garrels, F. Stanke, C. Miskey, S. M. Johler, Y. Kumar, B. Tümmler, C. Rudolph, Z. Ivics, [...] Ackermann, B. Tümmler, A. Munder. Mol Ther 2020:S1525-0016(20)30660-2. Why? -Successful Pseudomonas aeruginosa clones with a focus on clone. C. Lee, J. Klockgether, S. Fischer, J. Trcek, B. Tümmler, U. Römling

of the Work Group Lochner Most important publications: Beckstette M, C Lu, S Herppich, EC Diem, A Ntalli, A Ochel, F Kruse F, B Pietzsch, K Neumann, J Huehn, S Floess, M Lochner. 2022. Profiling of epigenetic [...] Fohse, I Prinz, J Pezoldt, S Suerbaum, T Sparwasser, A Hamann, S Floess, J Huehn, M Lochner. 2016. Foxp3(+) T cells expressing RORgammat represent a stable regulatory T-cell effector lineage with enhanced [...] Trends Immunol. 36(2):81-91. Wang, Z, C Friedrich, SC Hagemann, WH Korte, N Goharani, S Cording, G Eberl, T Sparwasser, M Lochner. 2014. Regulatory T cells promote a protective Th17-associated immune response

inflammasome activation through a microtubule-dependent mechanism. Li X, Thome S, Ma X, Amrute-Nayak M , Finigan A, Kitt L, Masters L, James JR, Shi Y, Meng G, Mallat Z. Nat Commun. 2017 Jun 28;8:15986 [...] Chen X, Amrute-Nayak M , Allgeyer E, Zhao A, Chenoweth H, Clement M, Harrison J, Doreth C, Sirinakis G, Krieg T, Zhou H, Huang H, Tokuraku K, Johnston DS, Mallat Z, Li X. Nature. 2021 May 26. doi: 10.103 [...] 31141694; PubMed Transformation of the Nonprocessive Fast Skeletal Myosin II into a Processive Motor. Amrute-Nayak M , Nayak A, Steffen W, Tsiavaliaris G, Scholz T, Brenner B. Small. 2019 Feb;15(7):e1804313

humanen Adenovirustypen, einschließlich der vor kurzem entdeckten neuen Typen bzw. Subtypen 14p1 und 21a (Pneumonie und ARDS assoziiert), 52 (der neuen Spezies G) und des neuen Keratokonjunktivitiseregers [...] komplett genomisch zu sequenzieren („next generation sequencing“). Dies ist ein großer Fortschritt, wenn z. B. ein Adenovirusisolat nicht typisierbar ist, für ein Krankheitsbild ungewöhnliche Typisierungsergebnisse [...] assoziierten Adenovirustypen gehört, Typ 70, außerdem der wahrscheinlich besonders virulente Subtyp 21a. Forschungsprojekte sind die Evolution der humanen der Adenoviren, ihre pathogenetischen Mechanismen

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Salazar A, Chercoles AG, Palom A, Ruiz A, Garcia-Fernandez AE, Blanco-Grau A, Mantovani A, Zanella A, Holten AR, Mayer A, Bandera A, Cherubini A, Protti A, Aghemo A, Gerussi A, Ramirez A, Braun A, Nebel [...] Nebel A, Barreira A, Lleo A, Teles A, Kildal AB, Biondi A, Caballero-Garralda A, Ganna A, Gori A, Gluck A, Lind A, Tanck A, Hinney A, Nolla AC, Fracanzani AL, Peschuck A, Cavallero A, Dyrhol-Riise AM, Ruello [...] Sharma AR, Elkady A, Negro A, Günther A, Gutschalk A, Schönenberger S, Buture A, Murphy S, Paiva Nunes A, Tiede A, Puthuppallil Philip A, Mengel A, Medina A, Hellstrom Vogel A, Tawa A, Aujayeb A, Casolla B,

Stimulation.Lenz, M., Eichler, A., Kruse, P., Strehl, A., Rodriguez-Rozada, S., Goren, I., Yogev, N., Frank, S., Waisman, A., Deller, T., Jung, S., Maggio, N., & Vlachos, A. (2020). Frontiers in Immunology [...] at Hippocampal Mossy Fiber Synapses. Kruse, P., Brandes, G., Hemeling, H., Huang, Z., Wrede, C., Hegermann, J., Vlachos, A., & Lenz, M. (2024). Cells , 13(2), 114. https://doi.org/10.3390/cells13020114 The [...] Perforant Path Synapses. Lenz, M., Eichler, A., Kruse, P., Galanis, C., Kleidonas, D., Andrieux, G., Boerries, M., Jedlicka, P., Müller, U., Deller, T., & Vlachos, A. (2023). The Journal of Neuroscience : The

Leffler A, Spohn M, Brown RJP, Kropp KA, Kaever V , Ha TC, Narayanan P, Grundhoff A, Förster R, Schambach A, Verjans GMGM, Schmidt M, Kispert A, Cantz T, Gomis A, Wegner F, Viejo-Borbolla A. Generation [...] Microbiomes 2022; 8: 39. doi: 10.1038/s41522-022-00294-z. Mederacke I, Filliol A, Affo S, Nair A, Hernandez C, Sun Q, Hamberger F, Brundu F, Chen Y, Ravichandra A, Huebener P, Anke H, Shi H, Martínez García de [...] Bähre H , Geffers R, Seifert R , Møller JE, Wende AR, Bauersachs J, Schäfer A. miRNA-200b-A Potential Biomarker Identified in a Porcine Model of Cardiogenic Shock and Mechanical Unloading. Front Cardiovasc

N, Moin M, Pourpak Z, Ramyar A, Izadyar M, Chavoshzadeh Z, Sherkat R, Aghamohammadi A, Yeganeh M, Mahmoudi M, Mahjoub F, Germeshausen M, Grudzien M, Horwitz MS, Klein C, Farhoudi A. J Clin Immunol. 2007 [...] Epub 2013 Apr 2. PMID: 23463630 A novel G6PC3 gene mutation in a patient with severe congenital neutropenia. Aytekin C, Germeshausen M, Tuygun N, Dogu F, Ikinciogullari A. J Pediatr Hematol Oncol. 2013 [...] thrombocytopenias, ANKRD26-related Thrombocytopenia and MYH9-related diseases. Balduini A, Raslova H, Di Buduo CA, Donada A, Ballmaier M, Germeshausen M, Balduini CL. Eur J Med Genet. 2018 Nov;61(11):715-722

F, van Meel M, Groenevelt T, Tieken I, Ankerst D, Renders L, Novotny A, Hartmann D, Jell A, Rahmel A, Wahba R, Mühlfeld A, Bouts A, Ysebaert D, Globke B, Jacobs-Tulleneers-Thevissen D, Piros L, Stippel [...] Ivanecz A, Choi SH, Lee JH, Gastaca M, Vivarelli M, Giuliante F, Ruzzenente A, Yong CC, Yin M, Fondevila C, Efanov M, Morise Z, Di Benedetto F, Brustia R, Valle RD, Boggi U, Geller D, Belli A, Memeo R [...] Amiot BP, Felgendreff L, Minshew A, Sultan A, Ahmadzada B, Rahe MC, Nyberg SL. Clinical characterization of a hypersensitivity mixed bacterial and fungal dermatitis in a translational model of porcine NASH