Paper in Stem Cell Reports “Efficient designer nuclease-based homologous recombination enables direct PCR screening for footprintless targeted human pluripotent stem cells”, Stem Cell Reports 2014 Genetic [...] Genetic engineering of human induced pluripotent stem cells (hiPSCs) via customized designer nucleases has been shown to be significantly more efficient than conventional gene targeting, but still typically [...] Dreyer, A. K., Schwanke, K., Meyer, J., Gohring, G., Cathomen, T., and Martin, U. 2014. Efficient designer nuclease-based homologous recombination enables direct PCR screening for footprintless targeted

products and cell-based immunotherapies within the project. Designer immune cells can be used in many ways And the potential of such designer immune cells is huge: for example, they can be genetically modified [...] the efficacy and safety of drugs. For this project, he is also building the project "IMMUNITY - Designer Cells: New immune cell platforms for health research", which is being supported by the Fraunhof

and coffee 09:00 – 10:00 | Design of a clinical trial protocol for MRD guided clinical trials in AML (Michael Heuser, All) 10:00 – 10:15 | Coffee break 10:15 – 11:15 | Design of a clinical trial protocol [...] collaborations in the future and co-ordinate harmozined MRD assessment across Europe. TOP 1 How to design clinical trials in AML or CLL using MRD as a surrogate endpoint or starting point? TOP 2 How to achieve [...] for MRD guided clinical trials in CLL (Paolo Ghia, Lydia Scarfó, All) 11:15 – 12:00 | Statistical design of MRD guided clinical trials (Axel Benner, Georgios Karakatsoulis) 12:00 – 13:00 | Lunch break 13:00

external auditory canal featuring drug release benefits. The implant is 3D printed and additionally designed to continuously and locally release an active ingredient to accelerate healing. "We have thus opened [...] Dr. Verena Scheper, whose team from the Otolaryngology Clinic's Inner Ear Pharmacology Department designed the implant and manufactured it using the 3D-Bioplotter Manufacturing Series Background: The MHH

manipulated. We connect basic and translational research in the fields of infection research, vaccine design, and immune therapies. In our research we employ state-of-the-art technologies such as 2-photon- [...] g of T cell responses in the setting of immune therapies and susceptible patient groups, and the design of new vaccine strategies. The Institute of Immunology is embedded and contributes to the strong

actually be used on patients one day has accompanied me my entire professional life," he notes. A designer protein he has been involved in developing for more than ten years is currently undergoing clinical [...] and has recently successfully completed two phase II trials. He is currently developing several designer proteins in order to be able to intervene therapeutically in other diseases as well. The biochemist

in Motor Proteins Cytoskeleton Dynamics and Motility of Cellular Systems Protein Engineering and Design of Tunable Biohybrid Systems Allosteric Effector Molecules in Cancer and Cardiovascular Diseases

structural biology, with topics including, amongst others, molecular motors, cell movement and drug design. The following positions are currently vacant:

carefully planned experimental study design. Therefore, the planning stage is the ideal time to get in contact with us. Manuals Introduction to experimental Microarray designs PDF Introduction to standard Excel

experimental design and the correct analysis strategy for a research project. In cooperation projects, the institute supports the grant application with an elaborated statistical test design. In clinical [...] services in the areas of project management, medical writing, regulatory affairs, data management (eCRF design using Marvin or SecuTrial, data validation) and monitoring. Phase 1 studies can be conducted in the [...] already in the planning stage in questions regarding research proposals, adequate experimental designs and suitable methodological approaches as well as in the selection of appropriate data processing